Glycoside Hydrolase Family 47

Activities in Familyα-mannosidase (EC 3.2.1.113)
Mechanism Inverting
3D Structure Status( α / α ) 7
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Statistics GenBank accession (1482); Uniprot accession (225); PDB accession (22); 3D entries (6); cryst (0)
All (938) Bacteria (18) Eukaryota (920) Structure (6) Characterized (43)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-mannosidase (CkGH47;Caul_4035) 3.2.1.113 Caulobacter sp. K31 ABZ73160.1 B0SWV2 4AYO[A]
4AYP[A]
4AYQ[A]
4AYR[A]
5MEH[A]
5NE5[A]
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-1,2-mannosidase (Mns5;At1g27520) 3.2.1.113 Arabidopsis thaliana AAD45990.1
AAL08238.1
AAM14008.1
ADH93655.1
AEE30841.1
CAY05988.1
CAY09748.1
CAY33076.1
CAY38422.1
NP_564288.1
Q9SXC9  
 α-1,2-mannosidase I (Mns3;At1g30000) (ER) 3.2.1.113 Arabidopsis thaliana AAK96673.1
AAG12868.1
AAG52061.1
AAM13279.1
AEE31166.1
ANM57755.1
CAY05989.1
CAY06023.1
CAY09749.1
CAY09783.1
NP_564345.1
Q93Y37
Q9C8R9
 
 α-1,2-mannosidase I (Mns1;ManIb;AtMANIb;At1g51590) (Golgi) 3.2.1.113 Arabidopsis thaliana AAG52623.1
AAG12762.1
AAG29692.1
AAG50876.1
AAL91242.1
AAM91245.1
AEE32686.1
AEE32687.1
CAY05986.1
CAY09746.1
NP_175570.1
Q9C512  
 α-1,2-mannosidase I (Mns2;ManIa;AtMANIa;At3g21160) (Golgi) 3.2.1.113 Arabidopsis thaliana AAN41293.1
AAK92711.1
AEE76468.1
ANM65156.1
BAB01459.1
BAF01772.1
CAY05990.1
CAY06022.1
CAY09750.1
CAY09782.1
NP_566675.1
Q8H116
Q94A04
Q9LJB6
 
 α-1,2-mannosidase (Mns4;At5g43710) 3.2.1.113 Arabidopsis thaliana AAK43943.1
AAK64102.1
AED94999.1
ANM69209.1
ANM69210.1
BAB11298.1
CAY05987.1
CAY09747.1
CAY33075.1
CAY38421.1
NP_199184.1
Q9FG93  
 α-1,2-mannosidase (ManA;fManIB;AO090003000476) 3.2.1.113 Aspergillus oryzae RIB40 BAE57653.1
BAC07247.1
Q2ULB2  
 α-1,2-mannosidase (MsdS) 3.2.1.113 Aspergillus phoenicis ATCC 14332 BAA08634.1 Q12563  
 α-1,2-mannosidase I (MANS-3;T03G11.4) (possible fragment) 3.2.1.113 Caenorhabditis elegans Bristol N2 AAA82446.2
CCD68813.1
NP_508877.1
Q22120  
 α-1,2-mannosidase I (MANS-2;C52E4.5) 3.2.1.113 Caenorhabditis elegans Bristol N2 CAB01415.1
CBW48349.1
NP_506006.1
Q18788  
 α-1,2-mannosidase I (Mans1;MANS-1;D2030.1) 3.2.1.113 Caenorhabditis elegans Bristol N2 CAA98114.1
NP_492116.1
P90787  
 α-1,2-mannosidase I (MANS-4;ZC410.3) 3.2.1.113 Caenorhabditis elegans Bristol N2 CAA92567.1
CBK19517.1
NP_501577.1
Q23296  
 α-1,2-mannosidase (Mns1;CaMNS1) 3.2.1.113 Candida albicans ATCC 26555 AAN86059.2
AAO23958.1
Q875J2
Q8J0Q0
 
 α-1,2-mannosidase 3.2.1.113 Coccidioides posadasii Silveira ABB36773.3
ABB36773.2
Q3HYC1  
 α-1,2-mannosidase I (Mas-1;Mas1;Dmel_CG42275) 3.2.1.113 Drosophila melanogaster AAF46570.1
AAR30196.1
AAS65302.1
AAS65303.1
AAS65304.1
AAS65305.1
AAS65306.1
CAA57962.1
NP_727407.1
NP_996395.1
NP_996396.1
NP_996397.1
NP_996398.1
NP_996399.1
P53624  
 α-mannosidase 2 (α-Man-1;Mas-1;Dmel_CG32684) 3.2.1.113 Drosophila melanogaster CAA57963.1
AAF46571.3
AGB95245.1
NP_511105.2
P53625
P53625
 
 mannosyl-oligosaccharide 1,2-α-mannosidase (Man1) 3.2.1.113 Glycine max AAF16414.1
CAY06026.1
CAY09786.1
Q9SEH8  
 α-mannosidase IC (Man1C1) 3.2.1.113 Homo sapiens AAF97058.1
AAL55860.1
BAD92512.1
CAB50704.1
CAI19713.1
CAI19714.1
NP_065112.1
Q9NR34  
 α-mannosidase IA (Man1A1) 3.2.1.113 Homo sapiens CAA52831.1
AAH65827.1
AAV20804.1
ACM81173.1
ACM85933.1
CAB37989.1
CAB75695.1
CAB75695.2
CAI20315.1
NP_005898.2
P33908  
 α-mannosidase IB (Man1A2) 3.2.1.113 Homo sapiens AAC26169.1
AAC26200.1
AAC26201.1
AAH63300.1
ABH82306.1
ABH82332.1
ABH82333.1
ABH82334.1
ACM81248.1
ACM84625.1
BAB14518.1
BAG50997.1
CAC10451.1
CAE89930.1
CAE92341.1
CAH71079.1
CAH71080.1
CAI22315.1
CAI22316.1
CAI22317.1
CAI22318.1
NP_006690.1
O60476
Q9H8T4
 
 ER mannosyl-oligosaccharide α-1,2-mannosidase I (Man1B1;ERManI;hERManI) 3.2.1.113 Homo sapiens AAF03215.1
AAD45504.1
AAH02953.1
AAH06079.1
AAQ88830.1
ABA31377.1
ABA36377.1
ABA37959.1
ABA68636.1
ABA69639.1
ABA70021.1
ABA70144.1
ABC03965.1
ABC16000.1
ABE23455.1
ABE26018.1
ABE26291.1
ABH64528.1
ABH64651.1
ABH64808.1
ABH66037.1
ABH70856.1
ABH70979.1
ABH72493.1
ABH75608.1
ABH99393.1
ABI02498.1
ABI07299.1
ABI10947.1
ABI12149.1
ABJ19332.1
ABJ34327.1
ABJ43225.1
ABL21769.1
ABN29858.1
ABN30045.1
ABP27825.1
ABX93887.1
ABX96180.1
ABX96490.1
ABX96800.1
ABY04954.1
ABY18690.1
ACC17223.1
ACC32395.1
ACE08681.1
ACG89592.1
ACH31821.1
ACJ99887.1
ACK30491.1
ACM94998.1
ACM96778.1
ACN08779.1
ACP73753.1
ACS06379.1
ACS08553.1
ACW23746.1
ATG31856.1
BAC11060.1
BAD92513.1
BAG51987.1
BAG54653.1
BAG54664.1
BAG60691.1
BAG61117.1
CAB53680.2
CAC27261.1
CAF85799.1
CAF86770.1
CAH72871.2
CAH72887.1
CAI12781.1
NP_009161.1
NP_057303.1
NP_057303.2
Q8N2P4
Q9UFZ8
Q9UKM7
1FMI[A]
1FO2[A]
1FO3[A]
1X9D[A]
5KIJ[A]
5KK7[A,B]
 mannosyl-oligosaccharide α-1,2-mannosidase (Mns1;MNS1;PAS_chr2-1_0753) (ER) 3.2.1.113 Komagataella phaffii GS115 CAY69404.1
AOA68147.1
C4R1N0  
 α-1,2-mannosidase (MG00994.4;MGG_00994.6) 3.2.1.113 Magnaporthe oryzae 70-15 EDK02328.1
CAY05993.1
CAY09753.1
XP_368250.1
   
 α-mannosidase IB (Man1A2;Man1B ) 3.2.1.113 Mus musculus AAB60439.1
AAB60438.1
AAC34829.1
AAH49121.1
AAH68192.1
ABH82335.1
ABH82336.1
BAE31915.1
CAI26211.1
CAI26213.1
CAI26214.1
CAM19090.1
CAM19091.1
CAM22047.1
NP_034893.1
A2A724
P39098
 
 Golgi mannosyl-oligosaccharide 1,2-α-mannosidase IA (ManA1;Man1A;Man1A1;GMIA) 3.2.1.113 Mus musculus AAA17747.1
AAH15265.1
BAC27225.1
BAE28536.1
BAE32852.1
CAH33904.1
CAH33939.1
CAH56918.1
CBA11298.1
CBA12843.1
CBA34883.1
NP_032574.1
P45700
Q544T7
1NXC[A]
5KKB[A,B]
 α-1,2-mannosidase (EDEM3;LOC66967) 3.2.1.113 Mus musculus XP_193956.3
AAI38660.1
AAI45358.1
AAI45359.1
BAE79485.1
Q2HXL6  
 α-mannosidase (Mns1) 3.2.1.113 Ophiostoma novo-ulmi MH75 AAG48158.1
CAY06024.1
CAY09784.1
Q9HF86  
 α-1,2-mannosidase (Man1A1) 3.2.1.113 Oryctolagus cuniculus AAA17748.1 P45701  
 α-1,2-mannosidase (MsdC) 3.2.1.113 Penicillium citrinum BAA08275.1 P31723 1KKT[A,B]
1KRE[A,B]
1KRF[A,B]
2RI8[A,B]
2RI9[A,B]
 ER α-mannosidase (Mns1;ERManI;YJR131w;J2110) 3.2.1.113 Saccharomyces cerevisiae S288c AAA34799.1
CAA89662.1
CAY05981.1
CAY09741.1
CAY09788.1
NP_012665.1
P32906 1DL2[A]
1G6I[A]
 N-glycan α-1,2-exomannosidase / lectin (Mnl1;Htm1;EDEM;YHR204w) 3.2.1.113 Saccharomyces cerevisiae S288c AAB68370.1
AAV20147.1
CAY33072.1
CAY38418.1
CAY38430.1
NP_012074.1
D3DLF3
P38888
 
 1,2-α-mannosidase (fragment) 3.2.1.113 Scherffelia dubia CAC20907.1 Q9FET4  
 α-mannosidase (Mns1;SPAC2E1P5.01c;SPAPB1E7.13c) 3.2.1.113 Schizosaccharomyces pombe 972h- NP_594139.2
CAB86344.1
CAC36930.1
CAC36930.2
CAY06027.1
CAY09787.1
Q9P7C3  
 α-mannosidase 3.2.1.113 Spodoptera frugiperda AAB62720.1
AAN93483.1
O18498  
 ER α-1,2-mannosidase (MNS1;SPSK05990;HMPREF1624_05452) 3.2.1.113 Sporothrix schenckii ATCC 58251 ERS98665.1    
 Golgi α-1,2-mannosidase IA (ManIA;SsMANIA;SPSK05081;HMPREF1624_00663) 3.2.1.113 Sporothrix schenckii ATCC 58251 ERT02365.1    
 Golgi α-1,2-mannosidase IB (ManIB;SsMANIB;SPSK00737;HMPREF1624_07509) 3.2.1.113 Sporothrix schenckii ATCC 58251 ERS95974.1    
 Golgi α-1,2-mannosidase IC (ManIC;SsMANIC;SPSK06219;HMPREF1624_04865 3.2.1.113 Sporothrix schenckii ATCC 58251 ERS98086.1    
 α-1,2-mannosidase (EDEM2;SsEDEM2;SPSK08874;HMPREF1624_01595) 3.2.1.113 Sporothrix schenckii ATCC 58251 ERT03288.1    
 α-1,2-mannosidase (EDEM3;SsEDEM3;SPSK00397;HMPREF1624_00979) 3.2.1.113 Sporothrix schenckii ATCC 58251 ERT02678.1    
 α-mannosidase / Man9-mannosidase (Man1A1) 3.2.1.113 Sus scrofa CAA73105.1 O02773  
 α-1,2-mannosidase (MannI;TrMannI;Trire2_45717;TRIREDRAFT_45717) 3.2.1.113 Trichoderma reesei QM6a EGR51573.1
XP_006962575.1
   
 α-1,2-mannosidase (Mds1;MDS1) (class-I) 3.2.1.113 Trichoderma reesei QM9414 AAF34579.1
CAY06025.1
CAY09785.1
Q9P8T8 1HCU[A,B,C,D]
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