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Glycoside Hydrolase Family 47

Activities in FamilyMannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113);
Mechanism Inverting a
3D Structure Status( α / α ) 7 barrel
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Statistics GenBank accession (3084); Uniprot accession (69); PDB accession (23); 3D entries (6); cryst (0)
Summary
Download GH47 (9509) Taxonomic display Structure (6) Characterized (38)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-mannosidase (CkGH47;Caul_4035) 3.2.1.113 pubmed
 Caulobacter sp. K31 ABZ73160.1 B0SWV2 4AYO[A]
4AYP[A]
4AYQ[A]
4AYR[A]
5MEH[A]
5NE5[A]
8B5M[A]
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-1,2-mannosidase (Mns5;At1g27520) 3.2.1.113 pubmed
 Arabidopsis thaliana AAD45990.1
AAL08238.1
AAM14008.1
ADH93655.1
AEE30841.1
CAY05988.1
CAY09748.1
CAY33076.1
CAY38422.1
NP_564288.1		 D7R518
Q9SXC9		  
 α-1,2-mannosidase I (Mns3;At1g30000) (ER) 3.2.1.113 pubmed
 Arabidopsis thaliana AAK96673.1
AAG12868.1
AAG52061.1
AAM13279.1
AEE31166.1
ANM57755.1
CAY05989.1
CAY06023.1
CAY09749.1
CAY09783.1
NP_564345.1		 A0A178WR43
A0A1P8AM79
Q93Y37
Q9C8R9		  
 α-1,2-mannosidase I (Mns1;ManIb;AtMANIb;At1g51590) (Golgi) 3.2.1.113 pubmed
 Arabidopsis thaliana AAG52623.1
AAG12762.1
AAG29692.1
AAG50876.1
AAL91242.1
AAM91245.1
AEE32686.1
AEE32687.1
CAY05986.1
CAY09746.1
NP_175570.1		 A0A178W2E7
Q9C512		  
 α-1,2-mannosidase I (Mns2;ManIa;AtMANIa;At3g21160) (Golgi) 3.2.1.113 pubmed
 Arabidopsis thaliana AAN41293.1
AAK92711.1
AEE76468.1
ANM65156.1
BAB01459.1
BAF01772.1
CAY05990.1
CAY06022.1
CAY09750.1
CAY09782.1
NP_566675.1		 A0A1I9LRE8
Q0WM84
Q8H116
Q94A04
Q9LJB6		  
 α-1,2-mannosidase (Mns4;At5g43710) 3.2.1.113 pubmed
 Arabidopsis thaliana AAK43943.1
AAK64102.1
AED94999.1
ANM69209.1
ANM69210.1
BAB11298.1
CAY05987.1
CAY09747.1
CAY33075.1
CAY38421.1
NP_199184.1		 A0A1P8BC88
A0A1P8BC90
Q9FG93		  
 α-1,2-mannosidase (ManA;fManIB;AO090003000476) 3.2.1.113 pubmed
 Aspergillus oryzae RIB40 BAE57653.1
BAC07247.1		 Q2ULB2  
 α-1,2-mannosidase (MsdS) 3.2.1.113 pubmed
 Aspergillus phoenicis ATCC 14332 BAA08634.1 Q12563  
 α-1,2-mannosidase I (MANS-3;T03G11.4) (possible fragment) 3.2.1.113 pubmed
 Caenorhabditis elegans Bristol N2 AAA82446.2
CCD68813.1
NP_508877.1		 Q22120  
 α-1,2-mannosidase I (MANS-2;C52E4.5) 3.2.1.113 pubmed
 Caenorhabditis elegans Bristol N2 CAB01415.1
CBW48349.1
NP_506006.1		 Q18788  
 α-1,2-mannosidase I (Mans1;MANS-1;D2030.1) 3.2.1.113 pubmed
 Caenorhabditis elegans Bristol N2 CAA98114.1
NP_492116.1		 P90787  
 α-1,2-mannosidase I (MANS-4;ZC410.3) 3.2.1.113 pubmed
 Caenorhabditis elegans Bristol N2 CAA92567.1
CBK19517.1
NP_501577.1		 D3YT22
Q23296		  
 α-1,2-mannosidase (Mns1;CaMNS1) 3.2.1.113 pubmed
 Candida albicans ATCC 26555 AAN86059.2
AAO23958.1		 Q875J2
Q8J0Q0		  
 α-1,2-mannosidase 3.2.1.113 pubmed
 Coccidioides posadasii Silveira ABB36773.3
ABB36773.2		 E9CXX8
Q3HYC1		  
 α-mannosidase IC (Man1C1) 3.2.1.113 pubmed
 Homo sapiens AAF97058.1
AAL55860.1
BAD92512.1
CAB50704.1
CAI19713.1
CAI19714.1
NP_065112.1		 Q59G34
Q8WYU7
Q9NR34		  
 α-mannosidase IA (Man1A1) 3.2.1.113 pubmed
 Homo sapiens CAA52831.1
AAH65827.1
AAV20804.1
ACM81173.1
ACM85933.1
CAB37989.1
CAB75695.1
CAB75695.2
CAI20315.1
NP_005898.2		 P33908  
 α-mannosidase IB (Man1A2) 3.2.1.113 pubmed
 Homo sapiens AAC26169.1
AAC26200.1
AAC26201.1
AAH63300.1
ABH82306.1
ABH82332.1
ABH82333.1
ABH82334.1
ACM81248.1
ACM84625.1
BAB14518.1
BAG50997.1
CAC10451.1
CAE89930.1
CAE92341.1
CAH71079.1
CAH71080.1
CAI22315.1
CAI22316.1
CAI22317.1
CAI22318.1
NP_006690.1		 B3KMI5
O60476
Q68DE3
Q9H8T4		  
 ER mannosyl-oligosaccharide α-1,2-mannosidase I (Man1B1;ERManI;hERManI) 3.2.1.113 pubmed
 Homo sapiens AAF03215.1
AAD45504.1
AAH02953.1
AAH06079.1
AAQ88830.1
ABA31377.1
ABA36377.1
ABA37959.1
ABA68636.1
ABA69639.1
ABA70021.1
ABA70144.1
ABC03965.1
ABC16000.1
ABE23455.1
ABE26018.1
ABE26291.1
ABH64528.1
ABH64651.1
ABH64808.1
ABH66037.1
ABH70856.1
ABH70979.1
ABH72493.1
ABH75608.1
ABH99393.1
ABI02498.1
ABI07299.1
ABI10947.1
ABI12149.1
ABJ19332.1
ABJ34327.1
ABJ43225.1
ABL21769.1
ABN29858.1
ABN30045.1
ABP27825.1
ABX93887.1
ABX96180.1
ABX96490.1
ABX96800.1
ABY04954.1
ABY18690.1
ACC17223.1
ACC32395.1
ACE08681.1
ACG89592.1
ACH31821.1
ACJ99887.1
ACK30491.1
ACM94998.1
ACM96778.1
ACN08779.1
ACP73753.1
ACS06379.1
ACS08553.1
ACW23746.1
ATG31856.1
BAC11060.1
BAD92513.1
BAG51987.1
BAG54653.1
BAG54664.1
BAG60691.1
BAG61117.1
CAB53680.2
CAC27261.1
CAF85799.1
CAF86770.1
CAH72871.2
CAH72887.1
CAI12781.1
NP_009161.1
NP_057303.1
NP_057303.2		 A0A291FGE6
B3KQC5
B3KXZ1
B4DPS9
B4DR05
Q8N2P4
Q9UFZ8
Q9UKM7		 1FMI[A]
1FO2[A]
1FO3[A]
1X9D[A]
5KIJ[A]
5KK7[A,B]
 mannosyl-oligosaccharide α-1,2-mannosidase (Mns1;MNS1;PAS_chr2-1_0753) (ER) 3.2.1.113 pubmed
 Komagataella phaffii GS115 CAY69404.1
AOA68147.1		 C4R1N0  
 α-mannosidase IB (Man1A2;Man1B ) 3.2.1.113 pubmed
 Mus musculus AAB60439.1
AAB60438.1
AAC34829.1
AAH49121.1
AAH68192.1
ABH82335.1
ABH82336.1
BAE31915.1
CAI26211.1
CAI26213.1
CAI26214.1
CAM19090.1
CAM19091.1
CAM22047.1
NP_034893.1		 A2A724
P39098		  
 Golgi mannosyl-oligosaccharide 1,2-α-mannosidase IA (ManA1;Man1A;Man1A1;GMIA) 3.2.1.113 pubmed
 Mus musculus AAA17747.1
AAH15265.1
BAC27225.1
BAE28536.1
BAE32852.1
CAH33904.1
CAH33939.1
CAH56918.1
CBA11298.1
CBA12843.1
CBA34883.1
NP_032574.1		 P45700
Q3UFM4
Q544T7		 1NXC[A]
5KKB[A,B]
 α-1,2-mannosidase (EDEM3;LOC66967) 3.2.1.113 pubmed
 Mus musculus XP_193956.3
AAI38660.1
AAI45358.1
AAI45359.1
BAE79485.1		 B7ZNN9
B7ZNP0
Q2HXL6		  
 α-1,2-mannosidase (Man1A1) (partial) 3.2.1.113 pubmed
 Oryctolagus cuniculus AAA17748.1 P45701  
 α-1,2-mannosidase (MsdC) 3.2.1.113 pubmed
 Penicillium citrinum BAA08275.1 P31723 1KKT[A,B]
1KRE[A,B]
1KRF[A,B]
2RI8[A,B]
2RI9[A,B]
 α-1,2-mannosidase (MG00994.4;MGG_00994.6) 3.2.1.113 pubmed
 Pyricularia oryzae 70-15 EDK02328.1
CAY05993.1
CAY09753.1
XP_368250.1		    
 ER α-mannosidase (Mns1;ERManI;YJR131w;J2110) 3.2.1.113 pubmed
 Saccharomyces cerevisiae S288c AAA34799.1
CAA89662.1
CAY05981.1
CAY09741.1
CAY09788.1
NP_012665.1		 P32906 1DL2[A]
1G6I[A]
 N-glycan α-1,2-exomannosidase / lectin (Mnl1;Htm1;EDEM;YHR204w) 3.2.1.113 pubmed
 Saccharomyces cerevisiae S288c AAB68370.1
AAV20147.1
CAY33072.1
CAY38418.1
CAY38430.1
NP_012074.1		 D3DLF3
P38888		  
 α-mannosidase (Mns1;SPAC2E1P5.01c;SPAPB1E7.13c) 3.2.1.113 pubmed
 Schizosaccharomyces pombe 972h- NP_594139.2
CAB86344.1
CAC36930.1
CAC36930.2
CAK8727290.1
CAY06027.1
CAY09787.1		 Q9P7C3  
 α-mannosidase 3.2.1.113 pubmed
 Spodoptera frugiperda AAB62720.1
AAN93483.1		 O18498  
 ER α-1,2-mannosidase (MNS1;SPSK05990;HMPREF1624_05452) 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERS98665.1 U7PW16  
 Golgi α-1,2-mannosidase IA (ManIA;SsMANIA;SPSK05081;HMPREF1624_00663) 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERT02365.1 U7Q5R2  
 Golgi α-1,2-mannosidase IB (ManIB;SsMANIB;SPSK00737;HMPREF1624_07509) 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERS95974.1 U7PMM4  
 Golgi α-1,2-mannosidase IC (ManIC;SsMANIC;SPSK06219;HMPREF1624_04865 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERS98086.1 U7PT23  
 α-1,2-mannosidase (EDEM2;SsEDEM2;SPSK08874;HMPREF1624_01595) 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERT03288.1 U7Q625  
 α-1,2-mannosidase (EDEM3;SsEDEM3;SPSK00397;HMPREF1624_00979) 3.2.1.113 pubmed
 Sporothrix schenckii ATCC 58251 ERT02678.1 U7Q496  
 α-mannosidase / Man9-mannosidase (Man1A1) 3.2.1.113 pubmed
 Sus scrofa CAA73105.1 O02773  
 α-1,2-mannosidase (MannI;TrMannI;Trire2_45717;TRIREDRAFT_45717) 3.2.1.113 pubmed
 Trichoderma reesei QM6a EGR51573.1
XP_006962575.1		 G0RBB5  
 α-1,2-mannosidase (Mds1;MDS1) (class-I) 3.2.1.113 pubmed
 Trichoderma reesei QM9414 AAF34579.1
CAY06025.1
CAY09785.1		 Q9P8T8 1HCU[A,B,C,D]
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