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Glycoside Hydrolase Family 44

Known Activitiesendoglucanase (EC 3.2.1.4); xyloglucanase (EC 3.2.1.151)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu
Catalytic Proton DonorGlu
Noteformerly known as cellulase family J. Note that the stereochemistry of the reaction has recently been corrected : Kitago et al., J. Biol. Chem. 282(2007)35703-11 (PMID: 17905739)
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (44); Uniprot accession (18); PDB accession (10); 3D entries (3); cryst (0)
Summary
All (33) Bacteria (32) Eukaryota (1) Structure (3 ) Characterized (10)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 Acid345_1503   Acidobacteria bacterium Ellin345 ABF40505.1 Q1IRJ5  
 Athe_1859   Anaerocellum thermophilum DSM 6725 ACM60947.1    
 β-mannanase/endo-β-1,4-glucanase (ManA) 3.2.1.4
3.2.1.78		 Caldicellulosiruptor saccharolyticus AAA71887.1 P22533.2  
 Csac_1077 (ManA)   Caldicellulosiruptor saccharolyticus DSM 8903 ABP66691.1 A4XIF6  
 CelE   Caldicellulosiruptor sp. Tok7B.1 AAK06389.1
AAK06394.1		 Q9AQG4  
 endoglucanase (EG;CAC0915) 3.2.1.4
3.2.1.8		 Clostridium acetobutylicum ATCC 824 AAK78891.1
NP_347551.1		 Q977Y3 3IK2[A]
 Ccel_0429 (P99) (Cel44O)   Clostridium cellulolyticum H10 ATCC 35319 ACL74812.1    
 Cthe_0624 (CelJ) (Cel9D+Cel44A)   Clostridium thermocellum ATCC 27405 ABN51859.1 A3DD30  
 endoglucanase (CelJ) (Cel9D-Cel44A) 3.2.1.4 Clostridium thermocellum F1 BAA12070.1 P71140 2D8G
2E0P[A]
2E4T[A]
2EEX[A]
2EJ1[A]
2EO7[A]
2EQD[A]
 Cwoe_3062   Conexibacter woesei DSM 14684 ADB51481.1    
 DICTH_1802 Fragment N-Term   Dictyoglomus thermophilum H-6-12 ATCC 35947 ACI18797.1 B5YB88  
 Dtur_0097   Dictyoglomus turgidum DSM 6724 ACK41435.1    
 Dfer_1570   Dyadobacter fermentans DSM 18053 ACT92814.1    
 Fisuc_0323   Fibrobacter succinogenes subsp. succinogenes S85 ACX73935.1    
 Sequence 15196 from patent US 6833447   Myxococcus xanthus AAW97633.1    
 MXAN_7450 (fragment)   Myxococcus xanthus DK 1622 ABF90156.1 Q1CVL8  
 DAMO_1282 (CelM)   NC10 bacterium 'Dutch sediment' CBE68342.1    
 Oter_4304   Opitutus terrae PB90-1 ACB77577.1 B1ZP88  
 endo-β-1,4-glucanase A (CelA) 3.2.1.4 Paenibacillus lautus PL236 AAA22303.1
CAA01933.1		 P29719.1  
 xyloglucanase 3.2.1.151 Paenibacillus pabuli AAW12878.1
ACE10761.1		    
 xyloglucanase 3.2.1.151 Paenibacillus polymyxa AAW12877.1
ACE10760.1		    
 xyloglucanase / mannanase (Cel44C-Man26A) 3.2.1.151
3.2.1.78		 Paenibacillus polymyxa GS01 AAW12876.1
ABC88431.1
ACE10759.1		    
 cellulase (EndB)   Ruminococcus flavefaciens 17 CAC83072.1 Q934F9  
 endo-1,4-glucanase B (CelB) 3.2.1.4 Ruminococcus flavefaciens FD-1 AAA95959.1 Q52743  
 sce1498   Sorangium cellulosum 'So ce 56' CAN91656.1 A9FCE8  
 Slin_4317   Spirosoma linguale DSM 74 ADB40299.1    
 sync_1467   Synechococcus sp. CC9311 ABI45742.1 Q0IA50  
 TERTU_4054   Teredinibacter turnerae T7901 ACR11610.1    
 TERTU_2311   Teredinibacter turnerae T7901 ACR12863.1    
 bifunctional glucanase-xylanase (CelM2) 3.2.1.4
3.2.1.8		 uncultured bacterium ABL11223.1 A1E9A6 3FW6[A]
3II1[A]
 cellulase (fragment)   uncultured bacterium AAT36619.1 Q6IZE2  
 cellulase (fragment)   uncultured bacterium AAT36618.1 Q6IZE3