Known Activities	endoglucanase (EC 3.2.1.4); xyloglucanase (EC 3.2.1.151)
Mechanism	Retaining
3D Structure Status	( β / α ) 8
Catalytic Nucleophile/Base	Glu
Catalytic Proton Donor	Glu
Note	formerly known as cellulase family J. Note that the stereochemistry of the reaction has recently been corrected : Kitago et al., J. Biol. Chem. 282(2007)35703-11 (PMID: 17905739)
External resources	CAZypedia;
Commercial Enzyme Provider(s)	NZYTech; PROZOMIX;
Statistics	GenBank accession (70); Uniprot accession (39); PDB accession (14); 3D entries (4); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
RAM_40260		Amycolatopsis mediterranei S699	AEK46519.1
RAM_40220		Amycolatopsis mediterranei S699	AEK46511.1
AMED_7833		Amycolatopsis mediterranei U32	ADJ49540.1	D8HQB6
AMED_7825		Amycolatopsis mediterranei U32	ADJ49533.1	D8HQA9
Athe_1859		Anaerocellum thermophilum DSM 6725	ACM60947.1	B9MKT9
Calkr_0017		Caldicellulosiruptor kristjanssonii 177R1B	ADQ39606.1	E4S5E5
Calkro_0851		Caldicellulosiruptor kronotskyensis 2002	ADQ45728.1	E4SDB9
Calla_0017		Caldicellulosiruptor lactoaceticus 6A	AEM72713.1
bifunctional β-mannanase / endo-β-1,4-glucanase (ManA)	3.2.1.78	Caldicellulosiruptor saccharolyticus	AAA71887.1	P22533.2
Csac_1077 (ManA)		Caldicellulosiruptor saccharolyticus DSM 8903	ABP66691.1	A4XIF6
CelE		Caldicellulosiruptor sp. Tok7B.1	AAK06389.1 AAK06394.1	Q9AQG4
Acid345_1503		Candidatus Koribacter versatilis Ellin345	ABF40505.1	Q1IRJ5
endoglucanase (EG;CAC0915)	3.2.1.4 3.2.1.8	Clostridium acetobutylicum ATCC 824	AAK78891.1 NP_347551.1	Q977Y3	3IK2[A]
SMB_G0932 (CelA)		Clostridium acetobutylicum DSM 1731	AEI34285.1
CEA_G0927		Clostridium acetobutylicum EA 2018	ADZ19966.1
Ccel_0429 (P99) (Cel44O)		Clostridium cellulolyticum H10 ATCC 35319	ACL74812.1	B8I5Z5
Clocel_3650		Clostridium cellulovorans 743B	ADL53320.1	D9SWN8
Clocl_1564		Clostridium clariflavum DSM 19732	AEV68200.1
Clo1100_1420		Clostridium sp. BNL1100	AEY65654.1
Cthe_0624 (CelJ) (Cel9D+Cel44A)		Clostridium thermocellum ATCC 27405	ABN51859.1	A3DD30
Clo1313_1604		Clostridium thermocellum DSM 1313	ADU74665.1
endoglucanase (CelJ) (Cel9D-Cel44A)	3.2.1.4	Clostridium thermocellum F1	BAA12070.1	P71140	2D8G 2E0P[A] 2E4T[A] 2EEX[A] 2EJ1[A] 2EO7[A] 2EQD[A]
Cwoe_3062		Conexibacter woesei DSM 14684	ADB51481.1	D3FCW9
DICTH_1802 Fragment N-Term		Dictyoglomus thermophilum H-6-12 ATCC 35947	ACI18797.1	B5YB88
Dtur_0097		Dictyoglomus turgidum DSM 6724	ACK41435.1	B8DYQ3
Dfer_1570		Dyadobacter fermentans DSM 18053	ACT92814.1	C6VSJ2
Fisuc_0323 / FSU_0738		Fibrobacter succinogenes subsp. succinogenes S85	ACX73935.1 ADL25160.1	C9RKK7
LILAB_09075		Myxococcus fulvus HW-1	AEI63726.1
Sequence 15196 from patent US 6833447		Myxococcus xanthus	AAW97633.1
MXAN_7450 (fragment)		Myxococcus xanthus DK 1622	ABF90156.1	Q1CVL8
DAMO_1282 (CelM)		NC10 bacterium 'Dutch sediment'	CBE68342.1	D5MF13
Niako_2423		Niastella koreensis GR20-10	AEV98765.1
Oter_4304		Opitutus terrae PB90-1	ACB77577.1	B1ZP88
endo-β-1,4-glucanase A (CelA)	3.2.1.4	Paenibacillus lautus PL236	AAA22303.1 CAA01933.1	P29719.1
xyloglucanase	3.2.1.151	Paenibacillus pabuli	AAW12878.1 ACE10761.1
xyloglucanase	3.2.1.151	Paenibacillus polymyxa	AAW12877.1 ACE10760.1
PPE_04361		Paenibacillus polymyxa E681	ADM72121.1	E0RHJ0
xyloglucanase / β-mannanase (Cel44C-Man26A)	3.2.1.4 3.2.1.78	Paenibacillus polymyxa GS01	AAW12876.1 ABC88431.1 ACE10759.1		2YIH[A] 2YJQ[A,B] 2YKK[A] 3ZQ9[A]
PPSC2_c4860		Paenibacillus polymyxa SC2	ADO58801.1	E3EAP2
HPL003_04315		Paenibacillus terrae HPL-003	AET57632.1
Rumal_1503		Ruminococcus albus 7	ADU22004.1	E0L8P0
cellulase (EndB)	3.2.1.4	Ruminococcus flavefaciens 17	CAC83072.1	Q934F9
xyloglucanase / endo-β-1,4-glucanase B (CelB)	3.2.1.151 3.2.1.4	Ruminococcus flavefaciens FD-1	AAA95959.1	Q52743
RUM_05910		Ruminococcus sp. 18P13	CBL16808.1	D4LB13
Runsl_1404		Runella slithyformis DSM 19594	AEI47830.1
sce1498		Sorangium cellulosum 'So ce 56'	CAN91656.1	A9FCE8
Slin_4317		Spirosoma linguale DSM 74	ADB40299.1	D2QLK9
STAUR_7877		Stigmatella aurantiaca DW4/3-1	ADO75632.1	E3FNF9
SBI_09199		Streptomyces bingchenggensis BCW-1	ADI12317.1	D7C3V1
sync_1467		Synechococcus sp. CC9311	ABI45742.1	Q0IA50
TERTU_4054		Teredinibacter turnerae T7901	ACR11610.1	C5BUB1
TERTU_2311		Teredinibacter turnerae T7901	ACR12863.1	C5BK65
cellulase (fragment)		uncultured bacterium	AAT36619.1	Q6IZE2
cellulase (fragment)		uncultured bacterium	AAT36618.1	Q6IZE3
bifunctional glucanase-xylanase (CelM2)	3.2.1.4 3.2.1.8	uncultured bacterium	ABL11223.1	A1E9A6	3FW6[A] 3II1[A]

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