Known Activities	endoglucanase (EC 3.2.1.4); xyloglucanase (EC 3.2.1.151)
Mechanism	Retaining
3D Structure Status	( β / α ) 8
Catalytic Nucleophile/Base	Glu
Catalytic Proton Donor	Glu
Note	formerly known as cellulase family J. Note that the stereochemistry of the reaction has recently been corrected : Kitago et al., J. Biol. Chem. 282(2007)35703-11 (PMID: 17905739)
Commercial Enzyme Provider(s)	NZYTech; PROZOMIX;
Statistics	GenBank accession (50); Uniprot accession (19); PDB accession (10); 3D entries (3); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
Acid345_1503		Acidobacteria bacterium Ellin345	ABF40505.1	Q1IRJ5
AMED_7825		Amycolatopsis mediterranei U32	ADJ49533.1
AMED_7833		Amycolatopsis mediterranei U32	ADJ49540.1
Athe_1859		Anaerocellum thermophilum DSM 6725	ACM60947.1
β-mannanase/endo-β-1,4-glucanase (ManA)	3.2.1.4 3.2.1.78	Caldicellulosiruptor saccharolyticus	AAA71887.1	P22533.2
Csac_1077 (ManA)		Caldicellulosiruptor saccharolyticus DSM 8903	ABP66691.1	A4XIF6
CelE		Caldicellulosiruptor sp. Tok7B.1	AAK06389.1 AAK06394.1	Q9AQG4
endoglucanase (EG;CAC0915)	3.2.1.4 3.2.1.8	Clostridium acetobutylicum ATCC 824	AAK78891.1 NP_347551.1	Q977Y3	3IK2[A]
Ccel_0429 (P99) (Cel44O)		Clostridium cellulolyticum H10 ATCC 35319	ACL74812.1
Clocel_3650		Clostridium cellulovorans 743B	ADL53320.1
Cthe_0624 (CelJ) (Cel9D+Cel44A)		Clostridium thermocellum ATCC 27405	ABN51859.1	A3DD30
endoglucanase (CelJ) (Cel9D-Cel44A)	3.2.1.4	Clostridium thermocellum F1	BAA12070.1	P71140	2D8G 2E0P[A] 2E4T[A] 2EEX[A] 2EJ1[A] 2EO7[A] 2EQD[A]
Cwoe_3062		Conexibacter woesei DSM 14684	ADB51481.1
DICTH_1802 Fragment N-Term		Dictyoglomus thermophilum H-6-12 ATCC 35947	ACI18797.1	B5YB88
Dtur_0097		Dictyoglomus turgidum DSM 6724	ACK41435.1	B8DYQ3
Dfer_1570		Dyadobacter fermentans DSM 18053	ACT92814.1
Fisuc_0323		Fibrobacter succinogenes subsp. succinogenes S85	ACX73935.1 ADL25160.1
Sequence 15196 from patent US 6833447		Myxococcus xanthus	AAW97633.1
MXAN_7450 (fragment)		Myxococcus xanthus DK 1622	ABF90156.1	Q1CVL8
DAMO_1282 (CelM)		NC10 bacterium 'Dutch sediment'	CBE68342.1
Oter_4304		Opitutus terrae PB90-1	ACB77577.1	B1ZP88
endo-β-1,4-glucanase A (CelA)	3.2.1.4	Paenibacillus lautus PL236	AAA22303.1 CAA01933.1	P29719.1
xyloglucanase	3.2.1.151	Paenibacillus pabuli	AAW12878.1 ACE10761.1
xyloglucanase	3.2.1.151	Paenibacillus polymyxa	AAW12877.1 ACE10760.1
xyloglucanase / β-mannanase (Cel44C-Man26A)	3.2.1.151 3.2.1.78	Paenibacillus polymyxa GS01	AAW12876.1 ABC88431.1 ACE10759.1
cellulase (EndB)		Ruminococcus flavefaciens 17	CAC83072.1	Q934F9
endo-1,4-glucanase B (CelB)	3.2.1.4	Ruminococcus flavefaciens FD-1	AAA95959.1	Q52743
RUM_05910		Ruminococcus sp. 18P13	CBL16808.1
sce1498		Sorangium cellulosum 'So ce 56'	CAN91656.1	A9FCE8
Slin_4317		Spirosoma linguale DSM 74	ADB40299.1
SBI_09199		Streptomyces bingchenggensis BCW-1	ADI12317.1
sync_1467		Synechococcus sp. CC9311	ABI45742.1	Q0IA50
TERTU_4054		Teredinibacter turnerae T7901	ACR11610.1
TERTU_2311		Teredinibacter turnerae T7901	ACR12863.1
bifunctional glucanase-xylanase (CelM2)	3.2.1.4 3.2.1.8	uncultured bacterium	ABL11223.1	A1E9A6	3FW6[A] 3II1[A]
cellulase (fragment)		uncultured bacterium	AAT36619.1	Q6IZE2
cellulase (fragment)		uncultured bacterium	AAT36618.1	Q6IZE3
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
endoglucanase (37GP1)	3.2.1.4	Bankia gouldi	AAM56790.1 ABW61101.1 ABY00380.1 CAH68691.1 CAT81451.1