Glycoside Hydrolase Family 43

Activities in Familyβ-xylosidase (EC; α-L-arabinofuranosidase (EC; xylanase (EC; α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); [inverting] endo-α-1,5-L-arabinanase (EC; exo-β-1,3-galactanase (EC; β-D-galactofuranosidase (EC
Mechanism Inverting
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. 82:1686-1692 (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (18998); Uniprot accession (1416); PDB accession (101); 3D entries (46); cryst (2)
All (18353) Archaea (26) Bacteria (17633) Eukaryota (661) Viruses (5) unclassified (28) Structure (46 - 2 cryst) Characterized (183)
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 ORF   feces metagenome SJX74176.1     17
 β-xylosidase (GH43(A3);BN138_18)   termite gut metagenome CCO20830.1     11
 arabinanase 43A (G12-10;GH43b(G12);BN138_172) (Abn43A) termite gut metagenome CCO20984.1     4
 exo-α-L-1,5-arabinanase 43B (G12-19;GH43a(G12);BN138_181) (Abn43B) 3.2.1.- termite gut metagenome CCO20993.1     4
 α-L-arabinofuranosidase 51B-43C (G12-20;GH51-GH43(G12);BN138_182) (Abf51B-Abf43C) termite gut metagenome CCO20994.1     29
 BN138_229   termite gut metagenome CCO21041.1
 BN138_520   termite gut metagenome CCO21332.1     29
 BN138_521   termite gut metagenome CCO21333.1     4
 β-xylosidase / α-L-arabinofuranosidase (GH43(F3);BN138_114)
termite gut metagenome CCO20926.1     35
 BT-10   uncultured microorganism ADR64672.1 E5F2L7   19
 BT-10   uncultured microorganism ADR64672.1 E5F2L7   24
 ORF   uncultured organism ADD61475.1 D9ZDS1   12
 ORF (fragment)   uncultured organism ADD61491.1 D9ZDT7   10
 ORF   uncultured organism ADD61495.1 D9ZDU1   29
 ORF   uncultured organism ADD61498.1 D9ZDU4   10
 multimodular xylanase (fragment) 3.2.1.- uncultured organism ADD61461.1 D9ZDQ7   16
 β-xylosidase (RS223-BX) uncultured organism AFP23142.1   4MLG[A,B,C,D,E,F,G,H,I,J,K,L] 1
 ORF   uncultured organism AGU10366.1     1
 ORF   uncultured organism AGU10579.1     12
 ORF   uncultured organism AGU10644.1     10
 ORF   uncultured organism AGU10721.1     11
 ORF   uncultured organism AGU11112.1     1
 ORF   uncultured organism AGU11239.1     11
 ORF   uncultured organism AGU11281.1     34
 ORF   uncultured organism AGU11323.1     11
 ORF   uncultured organism AGU11393.1     12
 ORF (fragment)   uncultured prokaryote CRY97816.1     18
 Sequence 28492 from patent US 7504490.   unidentified ACP96274.1     14

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