Glycoside Hydrolase Family 43

Activities in Familyβ-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); xylanase (EC 3.2.1.8); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); [inverting] endo-α-1,5-L-arabinanase (EC 3.2.1.99); exo-β-1,3-galactanase (EC 3.2.1.145); β-D-galactofuranosidase (EC 3.2.1.146)
Mechanism Inverting
ClanGH-F
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. 82:1686-1692 (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (16722); Uniprot accession (1416); PDB accession (101); 3D entries (46); cryst (2)
All (16079) Archaea (19) Bacteria (15399) Eukaryota (588) Viruses (5) unclassified (68) Structure (46 - 2 cryst) Characterized (182)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 ORF   feces metagenome SJX74176.1     17
 β-xylosidase (GH43(A3);BN138_18)   termite gut metagenome CCO20830.1     11
 arabinanase 43A (G12-10;GH43b(G12);BN138_172) (Abn43A) 3.2.1.99 termite gut metagenome CCO20984.1     4
 exo-α-L-1,5-arabinanase 43B (G12-19;GH43a(G12);BN138_181) (Abn43B) 3.2.1.- termite gut metagenome CCO20993.1     4
 α-L-arabinofuranosidase 51B-43C (G12-20;GH51-GH43(G12);BN138_182) (Abf51B-Abf43C) 3.2.1.55 termite gut metagenome CCO20994.1     29
 BN138_229   termite gut metagenome CCO21041.1
CCO21105.1
CCO21150.1
CCO21203.1
CCO21213.1
CCO21268.1
CCO21286.1
CCO21316.1
    1
 BN138_520   termite gut metagenome CCO21332.1     29
 BN138_521   termite gut metagenome CCO21333.1     4
 β-xylosidase / α-L-arabinofuranosidase (GH43(F3);BN138_114)   termite gut metagenome CCO20926.1     35
 BT-10   uncultured microorganism ADR64672.1 E5F2L7   19
 BT-10   uncultured microorganism ADR64672.1 E5F2L7   24
 ORF   uncultured organism ADD61475.1 D9ZDS1   12
 ORF (fragment)   uncultured organism ADD61491.1 D9ZDT7   10
 ORF   uncultured organism ADD61495.1 D9ZDU1   29
 ORF   uncultured organism ADD61498.1 D9ZDU4   10
 multimodular xylanase (fragment) 3.2.1.- uncultured organism ADD61461.1 D9ZDQ7   16
 β-xylosidase (RS223-BX) 3.2.1.37 uncultured organism AFP23142.1   4MLG[A,B,C,D,E,F,G,H,I,J,K,L] 1
 ORF   uncultured organism AGU10366.1     1
 ORF   uncultured organism AGU10579.1     12
 ORF   uncultured organism AGU10644.1     10
 ORF   uncultured organism AGU10721.1     11
 ORF   uncultured organism AGU11112.1     1
 ORF   uncultured organism AGU11239.1     11
 ORF   uncultured organism AGU11281.1     34
 ORF   uncultured organism AGU11323.1     11
 ORF   uncultured organism AGU11393.1     12
 ORF (fragment)   uncultured prokaryote CRY97816.1     18
 Sequence 28492 from patent US 7504490.   unidentified ACP96274.1     14
 GWR56_16280   unidentified QHS57021.1     26
 GWR55_15185   unidentified QHS53922.1     34
 GWR56_04565   unidentified QHS54855.1     34
 GWR56_13415   unidentified QHS56486.1     37
 GWR56_09900   unidentified QHS55828.1     28
 GWR55_01245   unidentified QHS50524.1     18
 GXP71_20025   unidentified QHT58138.1     36
 GXP71_08010   unidentified QHT56026.1     29
 GXP71_11850   unidentified QHT56702.1     4
 GXP71_03935   unidentified QHT55318.1     3
 GXP71_15950   unidentified QHT57414.1     5
 GXP71_11825   unidentified QHT58356.1     5
 GXP71_12545   unidentified QHT56822.1     29
 GXP71_05520   unidentified QHT55600.1     10
 GXP71_04195   unidentified QHT55362.1     4
 GXP67_26820   unidentified QHT70000.1     8
 GXP67_24960   unidentified QHT72158.1     33
 GXP67_26830   unidentified QHT70002.1     34
 GXP67_26845   unidentified QHT70005.1     26
 GXP67_31805   unidentified QHT70908.1     1
 GXP67_24985   unidentified QHT72160.1     26
 GXP67_24975   unidentified QHT72159.1     5
 GXP67_21490   unidentified QHT72120.1     26
 GXP67_31750   unidentified QHT70898.1     18
 GXP67_24955   unidentified QHT69665.1     17
 GXP67_21485   unidentified QHT69034.1     8
 GXP70_23045   unidentified QHT62572.1     1
 GXP70_09860   unidentified QHT60216.1     34
 GWR21_06045   unidentified QHS59163.1     33
 GWR21_24450   unidentified QHS62616.1     18
 GWR21_00815   unidentified QHS63900.1     1
 GWR21_27635   unidentified QHS63221.1     31
 GWR21_17420   unidentified QHS61312.1     26
 GWR21_06570   unidentified QHS63954.1     19
 GWR21_11360 (fragment)   unidentified QHS60175.1    
 GWR21_08140   unidentified QHS63963.1     10
 GWR21_09025 (fragment)   unidentified QHS59727.1     18
 GWR21_06000   unidentified QHS59156.1     8
 GWR21_10570   unidentified QHS60022.1     26
 GWR21_12915   unidentified QHS60460.1     34
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