Activities in Family	β-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); xylanase (EC 3.2.1.8); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); [inverting] endo-α-1,5-L-arabinanase (EC 3.2.1.99); exo-β-1,3-galactanase (EC 3.2.1.145); β-D-galactofuranosidase (EC 3.2.1.146)
Mechanism	Inverting
Clan	GH-F
3D Structure Status	5-fold β-propeller
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	Glu
Note	Many members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. 82:1686-1692 (PMID: 26729713).
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (16894); Uniprot accession (1416); PDB accession (101); 3D entries (46); cryst (2)

< | 1 | 2 | >
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
β-xylosidase (AmX;Amet_3317)	3.2.1.37	Alkaliphilus metalliredigens QYMF	ABR49445.1	A6TTC7		11
β-D-galactofuranosidase (weak activity) (AMED_5364)	3.2.1.146	Amycolatopsis mediterranei U32	ADJ47124.1	D8I4F0		37
β-xylosidase (XynB;XylBH43;BH3683)	3.2.1.37	Bacillus halodurans C-125	BAB07402.1 NP_244550.1	Q9K6P5	1YRZ[A,B]	11
BLi03029 or BL00353	3.2.1.99	Bacillus licheniformis DSM 13 = ATCC 14580	AAU41895.1 AAU24536.1	Q65GB9	6B7K[A,B,C,D]	5
endo-α-1,5-L-arabinanase (AbnA;BLABNase;BLi01295;BL02653)	3.2.1.99	Bacillus licheniformis DSM 13 = ATCC 14580	AAU40201.1 AAU22854.1 AAU22854.2	Q65L63		5
arabinoxylan α-arabinofuranosidase / AXH-m23 (XynD) (Arf43A=Axh43A)	3.2.1.55	Bacillus licheniformis SVD1	BAL45491.1			16
β-xylosidase (BpX;XynB;E-BXSEBP)	3.2.1.37	Bacillus pumilus IPO	CAA29235.1	P07129	5ZQJ[A,B] 5ZQS[A,B] 5ZQX[A,B,C,D]	11
β-xylosidase (XynB)	3.2.1.37	Bacillus pumilus PLS	AAC97375.1	Q9Z477	6IFE[A,B]	11
arabinoxylan arabinofuranohydrolase (AXH) (Axh43A)	3.2.1.55	Bacillus sp. BP-7	AKF02745.1			16
β-xylosidase (XylB)	3.2.1.37	Bacillus sp. KK-1	AAC27699.1	O52729		11
endo-α-1,5-L-arabinanase	3.2.1.99	Bacillus subtilis IFO3134	BAA20372.1	O07078		5
endo-α-1,5-L-arabinanase (Abn2;YxiA;J3A;BSU39330) (Arb43B)	3.2.1.99	Bacillus subtilis subsp. subtilis str. 168	CAB15969.2 ACB06752.1 AIY95249.1 AQR83975.1 AQR88190.1 CAB15969.1 NP_391812.1	B3FRL6 P42293	2X8F[A,B] 2X8S[A,B] 2X8T[A,B] 4COT[A]	4
endo-α-1,5-L-arabinanase (AbnA;BSU28810) (Arb43A)	3.2.1.99	Bacillus subtilis subsp. subtilis str. 168	CAA99586.1 AAV87172.1 AIY94210.1 AQR82908.1 AQR87123.1 CAB14841.1 CAB14841.2 NP_390759.1	P94522	1UV4[A]	5
β-1,4-xylosidase (BsX;XynB;YnaK;BSU17580)	3.2.1.37	Bacillus subtilis subsp. subtilis str. 168	AAB41091.1 AIY93062.1 AQR81741.1 AQR85955.1 CAB13642.1 CAB13642.2 NP_389640.1	P94489	1YIF[A,B,C,D]	11
arabinoxylan α-L-1,3-arabinofuranohydrolase (XynD;BsAXH-m23;BSU18160)	3.2.1.55	Bacillus subtilis subsp. subtilis str. 168	CAB13699.1 AIY93126.1 AQR81807.1 AQR86021.1 NP_389698.1	Q45071	3C7E[A] 3C7F[A] 3C7G[A] 3C7H[A] 3C7O[A]	16
α-L-arabinofuranosidase (BcellWH2_01652)	3.2.1.55	Bacteroides cellulosilyticus WH2	ALJ58905.1			19
α-L-arabinofuranosidase (BcellWH2_01652)	3.2.1.55	Bacteroides cellulosilyticus WH2	ALJ58905.1			34
β-D-galactofuranosidase (BcellWH2_02640;BACWH2_2462;Arba_1)	3.2.1.146	Bacteroides cellulosilyticus WH2	ALJ59879.1 WP_007211145.1			3
α-L-arabinofuranosidase (BcellWH2_04906;BACWH2_4625)	3.2.1.55	Bacteroides cellulosilyticus WH2	ALJ62115.1 WP_029328006.1			18
α-L-arabinofuranoside (weak activity) (BcellWH2_03560; BACWH2_3333)	3.2.1.55	Bacteroides cellulosilyticus WH2	ALJ60783.1 WP_029427512.1			18
β-xylosidase (BiXyl43A;BACINT_04203) (Xyl43A)	3.2.1.37	Bacteroides intestinalis DSM 17393	EDV05060.1			1
bifunctional endo-β-1,4-xylanase / α-L-arabinofuranosidase (BiXyn10B/BiAra43A;BACINT_04202) (Xyn10B/Ara43A)	3.2.1.55 3.2.1.8	Bacteroides intestinalis DSM 17393	EDV05059.1			12
α-L-arabinofuranosidase (BACOVA_03421;Bovatus_03717)	3.2.1.55	Bacteroides ovatus ATCC 8483	ALJ48322.1 EDO10788.1			12
α-L-arabinofuranosidase (BACOVA_03425;Bovatus_03721)	3.2.1.55	Bacteroides ovatus ATCC 8483	ALJ48326.1 EDO10792.1			12
double substituted xylan α-1,3-L-arabinofuranosidase (Bovatus_03715; Xynb_6; BACOVA_03417)	3.2.1.55	Bacteroides ovatus ATCC 8483	ALJ48320.1			10
α-L-arabinofuranoside (Xynb_4;BoGH43A;BACOVA_02654;Bovatus_03073)	3.2.1.55	Bacteroides ovatus ATCC 8483	ALJ47681.1		5JOW[A,B] 5JOX[A,B] 5JOY[A,B]	12
β-D-galactofuranosidase (Xsa_3;Bovatus_03644; revised model of BACOVA_03336 ZP_02066340.1)	3.2.1.146	Bacteroides ovatus ATCC 8483	ALJ48250.1			34
α-L-arabinofuranoside (Xynb_5;BoGH43B;BACOVA_02656;Bovatus_03074)	3.2.1.55	Bacteroides ovatus ATCC 8483	ALJ47682.1		5JOZ[A,B]	12
β-xylosidase / α-L-arabinofuranosidase (Xsa;XSA)	3.2.1.37 3.2.1.55	Bacteroides ovatus V975	AAB08024.1 ACA34973.1	B2KZK6 P49943		1
β-D-galactofuranosidase (HMPREF1071_01763)	3.2.1.146	Bacteroides salyersiae CL02T12C01	EIY66405.1			8
endo-α-1,5-L-arabinanase (BT0360;BT_0360) (branched arabinan specific)	3.2.1.99	Bacteroides thetaiotaomicron VPI-5482	AAO75467.1 NP_809273.1	Q8AAV4		4
endo-α-1,5-L-arabinanase (BT0367;BT_0367) (linear arabinan-specific)	3.2.1.99	Bacteroides thetaiotaomicron VPI-5482	AAO75474.1 NP_809280.1	Q8AAU7		4
α-L-arabinofuranosidase (BT3675;BT_3675)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO78780.1 NP_812586.1	Q8A1I6	3QZ4[A,B]	34
α-L-arabinofuranosidase (Bt3655;BT_3655) (single substitution specific)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO78760.1 NP_812566.1	Q8A1K6		19
exo-β-1,3-galactanase (BT0265;BT_0265)	3.2.1.145	Bacteroides thetaiotaomicron VPI-5482	AAO75372.1 NP_809178.1	Q8AB46	6EUF[A,B,C,D] 6EUJ[A,B,C,D]	24
α-L-arabinofuranosidase (cleaves L-Araf-α-1,3-D-GalpA; BT1021; BT_1021) (fragment)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO76128.1 NP_809934.1	Q8A8Z6		18
α-L-arabinofuranosidase (Bt2852;BT_2852) (single substitution specific)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO77958.1 NP_811764.1	Q8A3V2		10
α-1,2-L-arabinofuranosidase (BT0369;BT_0369)	3.2.1.-	Bacteroides thetaiotaomicron VPI-5482	AAO75476.1 NP_809282.1	Q8AAU5		29
(grape RGII active) α-L-arabinofuranosidase (BT3662;BT_3662)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO78767.1 NP_812573.1	Q8A1J9	5MSX[A,B,C]	34
α-L-arabinofuranosidase (Bt3094;BT_3094)	3.2.1.55	Bacteroides thetaiotaomicron VPI-5482	AAO78200.1 NP_812006.1	Q8A361
β-D-galactofuranosidase (Belba_3293)	3.2.1.146	Belliella baltica DSM 15883	AFL85801.1			31
double substituted xylan α-1,3-L-specific arabinofuranosidase d3 (AXHd3;AXH-d3;BaAXH-d3;BAD_0301;E-AFAM2)	3.2.1.55	Bifidobacterium adolescentis ATCC 15703	AAO67499.1 BAF39082.1	A1A049 Q5JB56		10
α-L-arabinofuranosidase (AXH-m;AbfA;BAD_0423)	3.2.1.55	Bifidobacterium adolescentis ATCC 15703	BAF39204.1	A1A0H1		12
β-xylosidase C (XylC;XynB;BAD_0428)	3.2.1.37	Bifidobacterium adolescentis ATCC 15703	BAF39209.1	A1A0H6		11
β-xylosidase (BAD_1527)	3.2.1.37	Bifidobacterium adolescentis ATCC 15703	BAF40308.1	A1A3M5		22
β-xylosidase (BIF_00092)	3.2.1.37	Bifidobacterium animalis subsp. lactis BB-12	ADC85541.1	D3R467		11
α-L-arabinofuranosidase (HypAA;BLLJ_0213)	3.2.1.55	Bifidobacterium longum subsp. longum JCM 1217	BAJ65883.1			29
exo-β-1,3-galactanase (BLLJ_1840)	3.2.1.145	Bifidobacterium longum subsp. longum JCM 1217	BAJ67504.1			24
α-L-arabinofuranosidase (BlArafC;BLLJ_1852)	3.2.1.55	Bifidobacterium longum subsp. longum JCM 1217	BAJ67516.1			27
α-L-arabinofuranosidase (BlArafB;BLLJ_1853)	3.2.1.55	Bifidobacterium longum subsp. longum JCM 1217	BAJ67517.1			22
α-L-arabinofuranosidase / β-xylosidase (XylB)	3.2.1.37 3.2.1.55	Butyrivibrio fibrisolvens GS 113	AAA63610.1	P45982		12
α-L-arabinofuranosidase (Xsa43E;bpr_I2319)	3.2.1.37 3.2.1.55	Butyrivibrio proteoclasticus B316	ADL35052.1	E0RYY0	4NOV[A]	29
α-L-arabinofuranosidase (Calow_2099)	3.2.1.55	Caldicellulosiruptor owensensis OL	ADQ05609.1	E4Q6K2		17
β-xylosidase / α-L-arabinofuranosidase (XynF)	3.2.1.37 3.2.1.55	Caldicellulosiruptor saccharolyticus	AAB87371.1	O30426		16
β-xylosidase / α-L-arabinofuranosidase (XynF)	3.2.1.37 3.2.1.55	Caldicellulosiruptor saccharolyticus	AAB87371.1	O30426		10
endo-α-1,5-L-arabinanase (Csac_1560)	3.2.1.99	Caldicellulosiruptor saccharolyticus DSM 8903	ABP67152.1	A4XJR7		4
bifunctional α-L-arabinofuranosidase (XynF;Csac_2411)	3.2.1.55	Caldicellulosiruptor saccharolyticus DSM 8903	ABP67988.1	A4XM53		16
bifunctional α-L-arabinofuranosidase (XynF;Csac_2411)	3.2.1.55	Caldicellulosiruptor saccharolyticus DSM 8903	ABP67988.1	A4XM53		10
xylanase C (XynC) (multidomain protein)	3.2.1.8	Caldicellulosiruptor sp. Rt69B.1	AAB95326.1	O52374		16
bifunctional β-1,4-xylanase / α-L-arabinosidase (XynA)	3.2.1.55 3.2.1.8	Caldicellulosiruptor sp. Tok7B.1	AAD30363.1	Q9X3P5		16
bifunctional β-xylosidase I / α-L-arabinofuranosidase (XynB1;CCNA_01040)	3.2.1.37 3.2.1.55	Caulobacter vibrioides NA1000	ACL94505.1	B8H2V1		11
β-xylosidase (CGSCsYakCAS_10615) (fragment) (Xyn43A)	3.2.1.-	Cellulosilyticum ruminicola CGMCC 1.5065	ACZ98594.1	D2KFJ2		16
endo-α-1,5-L-arabinanase / exo-α-1,5-L-arabinanase 43A (ArbA;CJA_0805) (Arb43A)	3.2.1.99 3.2.1.-	Cellvibrio japonicus Ueda107	ACE84667.1 CAA71485.1	B3PKP8 P95470	1GYD[B] 1GYE[B] 1GYH[A,B,C,D,E,F]	5
β-xylosidase 43A (CJA_3070) (Xyl43A=Gly43G)	3.2.1.37	Cellvibrio japonicus Ueda107	ACE82692.1	B3PDB2		1
exo-α-1,5-L-arabinofuranosidase 43K (CJA_3012) (Abf43K)	3.2.1.-	Cellvibrio japonicus Ueda107	ACE82749.1	B3PD54		26
α-1,2-L-arabinofuranosidase 43A (CJA_3018) (arabinan-specific) (Abf43A=Gly43N)	3.2.1.-	Cellvibrio japonicus Ueda107	ACE83886.1	B3PD60	3QED[A,B,C,D] 3QEE[A,B] 3QEF[A,B]	29
exo-α-1,5-L-arabinofuranosidase 43L (CJA_0806) (Abf43L)	3.2.1.-	Cellvibrio japonicus Ueda107	ACE84379.1	B3PKP9		26
α-L-arabinofuranosidase (Cpin_4501)	3.2.1.55	Chitinophaga pinensis DSM 2588	ACU61943.1	C7PJ75		2
β-xylosidase (Xyl43)	3.2.1.37	Enterobacter sp. enrichment culture clone nf1B6	AFZ78871.1			11
arabinoxylan α-L-arabinofuranosidase (Axh1;Fisuc_1769;FSU_2269)	3.2.1.55	Fibrobacter succinogenes subsp. succinogenes S85	ACX75362.1 ADL24843.1	C9RS26		10
Fisuc_1994 / FSU_2517	3.2.1.99	Fibrobacter succinogenes subsp. succinogenes S85	ACX75582.1 ADL26080.1	C9RIW1		37
β-xylosidase (BN863_22160)	3.2.1.37	Formosa agariphila KMM 3901	CDF79928.1			10
β-xylosidase (XynB3;HUS_CDS105)	3.2.1.37	Geobacillus stearothermophilus T-6 NCIMB 40222	AAT98625.1 ABI49959.1	Q09LX0	2EXH[A,B,C,D] 2EXI[A,B,C,D] 2EXJ[A,B,C,D] 2EXK[A,B,C,D]	11
α-1,5-L-arabinanase (AbnB;HUS_CDS25) (intracellular)	3.2.1.99	Geobacillus stearothermophilus T-6 NCIMB 40222	ACE73676.1	B3EYM8	3CU9[A] 3D5Y[A] 3D5Z[A] 3D60[A] 3D61[A] 6F1G[A]	5
endo-α-1,5-L-arabinanase (AbnA) (extracellular)	3.2.1.99	Geobacillus stearothermophilus T-6 NCIMB 40222	ACE73680.1	B3EYN2	5HO0[A] 5HO2[A] 5HO9[A,B] 5HOF[A] 5HP6[A]	4
endo-α-1,5-L-arabinanase (Abn-ts)	3.2.1.99	Geobacillus thermodenitrificans TS-3	BAB64339.1	Q93HT9	1WL7[A] 6A8H[A] 6A8I[A,B]	5
β-xylosidase (Xyl;GbtXyl43A) (Xyl43A)	3.2.1.37	Geobacillus thermoleovorans IT-08	ABC75004.1	Q2I2N4	5Z5D[A] 5Z5F[A] 5Z5H[A] 5Z5I[A]	12
β-xylosidase / exo-xylanase (GbtXyl43B) (Xyl43B)	3.2.1.37	Geobacillus thermoleovorans IT-08	ABD48561.1	Q27R94		27
α-L-arabinofuranosidase (HoAraf43;Hore_20580)	3.2.1.55	Halothermothrix orenii H 168	ACL70803.1	B8CZV1	4QQS[A,B]	33
[arabinogalactan] exo-β-1,3-galactanase (Ct1,3Gal43A;CtGH43;Cthe_0661) (1,3Gal43A)	3.2.1.145	Hungateiclostridium thermocellum ATCC 27405	ABN51896.1	A3DD67	3VSF[A,B,C,D,E,F] 3VSZ[A,B,C,D,E,F] 3VT0[A,B,C,D,E,F] 3VT1[A,B,C,D,E,F] 3VT2[A,B,C,D,E,F]	24
α-L-arabinofuranosidase (Ct43Araf;CtAbf43A;CtGh43;Cthe_1271) (Abf43A)	3.2.1.55	Hungateiclostridium thermocellum ATCC 27405	ABN52503.1	A3DEX4	5A8C[A] 5A8D[A]	16
β-xylosidase (XynB1)	3.2.1.37	Lactobacillus brevis ATCC 14869 = DSM 20054	AGT14429.1			11
α-1,5-L-arabinofuranosidase (Abf3)	3.2.1.-	Lactobacillus brevis ATCC 14869 = DSM 20054	AGT14430.1			26
β-xylosidase 2 (XynB2)	3.2.1.37	Lactobacillus brevis ATCC 14869 = DSM 20054	AGT14431.1			11
β-xylosidase (LbX;XynB2;LVIS_2285)	3.2.1.37	Lactobacillus brevis ATCC 367	ABJ65333.1	Q03N89		11
α-L-arabinofuranosidase II (Araf43;LbAraf43;N624_1993)	3.2.1.-	Lactobacillus brevis DSM 1269 / TMW 1.313	APU52333.1 KIO95879.1		5M8B[A,B]	26
β-D-galactofuranosidase (weak activity) (SAMN04515690_3677)	3.2.1.146	Leifsonia sp. 197AMF	SDH69004.1			32
α-L-arabinofuranoside (weak activity) (A3224_13575)	3.2.1.55	Microbulbifer thermotolerans DAU221	AMX03466.1			9
α-L-arabinofuranosidase (GA0070618_4635)	3.2.1.55	Micromonospora echinospora DSM 43816	SCF26596.1			20
β-D-galactofuranosidase (GA0074704_5727)	3.2.1.146	Micromonospora siamensis DSM 45097	SCG78792.1			30
α-L-arabinofuranosidase (SAMN05216490_0716)	3.2.1.55	Mucilaginibacter mallensis MP1X4	SDS19757.1			2
α-L-arabinofuranoside (weak activity) (B160DRAFT_01699)	3.2.1.55	Niabella aurantiaca	WP_018628786.1			18
β-xylosidase/α-L-arabinofuranosidase (XynA)	3.2.1.37 3.2.1.55	Niveispirillum irakense KBC1	AAF66622.1	Q9LAE3		11
α-L-arabinofuranosidase (OB2087)	3.2.1.55	Oceanobacillus iheyensis HTE831	BAC14043.1 NP_693008.1	Q8EPL4		12
α-L-arabinofuranoside (weak activity) (OPIT5_12740)	3.2.1.55	Opitutaceae bacterium TAV5	AHF90946.1			18
β-D-galactofuranosidase (weak activity) (Oter_3903)	3.2.1.146	Opitutus terrae PB90-1	ACB77177.1	B1ZZA2		32
α-L-arabinofuranosidase 43A (XynD) (formerly xylanase D) (Xyn43A)	3.2.1.55	Paenibacillus polymyxa ATCC 842	CAA40378.1	P45796		16
endo-α-1,5-L-arabinanase (AbnZ3;YxiA3)	3.2.1.99	Paenibacillus polymyxa Z6	AHA50064.1			4
endo-α-1,5-L-arabinanase (AbnZ2;Yxia1)	3.2.1.99	Paenibacillus polymyxa Z6	AHA50063.1			4
endo-α-1,5-L-arabinanase (AbnZ1)	3.2.1.99	Paenibacillus polymyxa Z6	AHA50062.1			5
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