Glycoside Hydrolase Family 43 / Subf 4

Activities in Familyβ-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); arabinanase (EC 3.2.1.99); xylanase (EC 3.2.1.8); galactan 1,3-β-galactosidase (EC 3.2.1.145); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Inverting
ClanGH-F
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. in press (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (462); Uniprot accession (83); PDB accession (14); 3D entries (5); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 endo-α-1,5-L-arabinanase (Abn2;YxiA;J3A;BSU39330) (Arb43B) 3.2.1.99 Bacillus subtilis subsp. subtilis str. 168 CAB15969.2
ACB06752.1
AIY95249.1
AQR83975.1
AQR88190.1
CAB15969.1
NP_391812.1
B3FRL6
P42293
2X8F[A,B]
2X8S[A,B]
2X8T[A,B]
4COT[A]
4
 endo-α-1,5-L-arabinanase (Bt0360;BT_0360) (branched arabinan specific) 3.2.1.99 Bacteroides thetaiotaomicron VPI-5482 AAO75467.1
NP_809273.1
Q8AAV4   4
 endo-α-1,5-L-arabinanase (Bt0367;BT_0367) (linear arabinan-specific) 3.2.1.99 Bacteroides thetaiotaomicron VPI-5482 AAO75474.1
NP_809280.1
Q8AAU7   4
 endo-α-1,5-L-arabinanase (Csac_1560) 3.2.1.99 Caldicellulosiruptor saccharolyticus DSM 8903 ABP67152.1 A4XJR7   4
 endo-α-1,5-L-arabinanase (AbnA) (extracellular) 3.2.1.99 Geobacillus stearothermophilus T-6 NCIMB 40222 ACE73680.1 B3EYN2 5HO0[A]
5HO2[A]
5HO9[A,B]
5HOF[A]
5HP6[A]
4
 endo-α-1,5-L-arabinanase (AbnZ3;YxiA3) 3.2.1.99 Paenibacillus polymyxa Z6 AHA50064.1     4
 endo-α-1,5-L-arabinanase (AbnZ2;Yxia1) 3.2.1.99 Paenibacillus polymyxa Z6 AHA50063.1     4
 endo-arabinanase (Abn;Tth Abn;Theth_1128) 3.2.1.99 Pseudothermotoga thermarum DSM 5069 AEH51204.1     4
 arabinanase (GH43D;RUM_09280) (Ara43D) 3.2.1.99 Ruminococcus champanellensis 18P13 = JCM 17042 CBL17100.1 D4LBV5   4
 endo-α-1,5-L-arabinanase (AbnA;TpABN;Tpet_0637) 3.2.1.99 Thermotoga petrophila RKU-1 ABQ46657.1 A5IKD4 4KC7[A,B,C]
4KC8[A,B,C]
4
 endo-α-1,5-L-arabinanase (Arn2) 3.2.1.99 uncultured bacterium ADB43998.1 D2XML7   4
 endo-α-1,5-L-arabinanase (Arn2;ARN2) (partial) 3.2.1.99 uncultured rumen bacterium     4KCA[A]
4KCA[B]
4
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 arabinanase 43A (G12-10;GH43b(G12);BN138_172) (Abn43A) 3.2.1.99 termite gut metagenome CCO20984.1     4
 exo-α-L-1,5-arabinanase 43B (G12-19;GH43a(G12);BN138_181) (Abn43B) 3.2.1.- termite gut metagenome CCO20993.1     4
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