Glycoside Hydrolase Family 43 / Subf 24

Activities in Familyβ-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); arabinanase (EC 3.2.1.99); xylanase (EC 3.2.1.8); galactan 1,3-β-galactosidase (EC 3.2.1.145); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Inverting
ClanGH-F
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. in press (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (392); Uniprot accession (82); PDB accession (7); 3D entries (4); cryst (1)
All (355) Bacteria (309) Eukaryota (45) unclassified (1) Structure (4 - 1 cryst) Characterized (9)
Bacteria
Protein Name EC# OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
Subf
 BT2959 / BT_2959   Bacteroides thetaiotaomicron VPI-5482 AAO78065.1
NP_811871.1
Q8A3J5
3NQH[A] 2.11
24
 exo-β-1,3-galactanase (BBIF_0009)   Bifidobacterium bifidum S17 ADO52214.1 E3END6
5FLW[A,B] 1.40
24
 [arabinogalactan] exo-β-1,3-galactanase (Ct1,3Gal43A;CtGH43;Cthe_0661) (1,3Gal43A) 3.2.1.145 Ruminiclostridium thermocellum ATCC 27405 ABN51896.1 A3DD67
3VSF[A,B,C,D,E,F] 2.76
3VSZ[A,B,C,D,E,F] β-D-Galp-(1-3)-β-D-Galp
β-D-Galp-(1-3)-β-D-Galp-(1-3)-β-D-Galp
2.89
3VT0[A,B,C,D,E,F] β-D-Galp-(1-4)-β-D-Glcp
2.91
3VT1[A,B,C,D,E,F] β-D-Galp
3.19
3VT2[A,B,C,D,E,F] β-D-Galp1S-(1-1)-<non_carb>
3.00
24
Eukaryota
Protein Name EC# OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
Subf
 exo-β-1,3-galactanase (Pc1,3Gal43A) (1,3Gal43A) 3.2.1.145 Phanerochaete chrysosporium BAD98241.1 Q50KB2
cryst    
24
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