Glycoside Hydrolase Family 43 / Subf 1

Activities in Family	β-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); arabinanase (EC 3.2.1.99); xylanase (EC 3.2.1.8); galactan 1,3-β-galactosidase (EC 3.2.1.145); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-)
	Activities in Sub Family
Mechanism	Inverting
Clan	GH-F
3D Structure Status	5-fold β-propeller
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	Glu
Note	Many members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. in press (PMID: 26729713).
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (678); Uniprot accession (54); PDB accession (9); 3D entries (2); cryst (0)

All (345) Bacteria (273) Eukaryota (68) unclassified (4) Structure (2) Characterized (16)

Bacteria

Protein Name

EC#

Organism

GenBank

Uniprot

PDB/3D

Carbohydrate Ligands

Resolution (Å)

Subf

β-xylosidase / α-L-arabinofuranosidase (CoXyl43)

5GLK[A,B]		1.70
5GLL[A,B]		1.80
5GLM[A,B]	β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp	1.80
5GLN[A,B]	α-D-Xylp β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp	1.70
5GLO[A,B]	α-L-Arap β-L-Araf	1.80
5GLP[A,B]	α-L-Arap	1.80
5GLQ[A,B]	β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp β-L-Araf	1.70
5GLR[A,B]	β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp β-L-Araf	1.70

unclassified