Glycoside Hydrolase Family 43 / Subf 12

Activities in Familyβ-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); arabinanase (EC 3.2.1.99); xylanase (EC 3.2.1.8); galactan 1,3-β-galactosidase (EC 3.2.1.145); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Inverting
ClanGH-F
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. 82:1686-1692 (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (751); Uniprot accession (106); PDB accession (8); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 arabinoxylan arabinofuranohydrolase (ORF2351) (Ara43A) 3.2.1.55 Prevotella bryantii B14 ADI70680.1 D7SFH6   12
 Prede_1758   Prevotella dentalis DSM 3688 AGB29055.1     12
 PSM36_3304   Proteiniphilum saccharofermentans SCD22089.1     12
 PSM36_3304   Proteiniphilum saccharofermentans SCD22089.1     12
 Achl_0430   Pseudarthrobacter chlorophenolicus A6 ACL38429.1 B8HAG8   12
 SAMN04489743_0689   Pseudarthrobacter equi IMMIB L-1606 SDS71896.1     12
 Patl_0842   Pseudoalteromonas atlantica T6c ABG39370.1 Q15XL8   12
 Pedsa_2580   Pseudopedobacter saltans DSM 12145 ADY53124.1     12
 Pedsa_2709   Pseudopedobacter saltans DSM 12145 ADY53251.1     12
 Psesu_2924   Pseudoxanthomonas suwonensis 11-1 ADV28748.1     12
 WQ53_05955   Pseudoxanthomonas suwonensis J1 AKC86381.1     12
 RHOM_05750   Roseburia hominis A2-183 AEN96269.1     12
 ROI_22640   Roseburia intestinalis M50/1 CBL09263.1 D4KQW1   12
 ROI_23910   Roseburia intestinalis M50/1 CBL09363.1 D4KR61   12
 ROI_37890   Roseburia intestinalis M50/1 CBL10563.1 D4KJN3   12
 RO1_13630   Roseburia intestinalis XB6B4 CBL11992.1 D4KXA2   12
 RO1_14860   Roseburia intestinalis XB6B4 CBL12098.1 D4KXK8   12
 RO1_26390   Roseburia intestinalis XB6B4 CBL13089.1 D4L0E9   12
 TH63_14725   Rufibacter sp. DG31D AKQ46600.1     12
 TH63_05320   Rufibacter sp. DG31D AKQ45183.1     12
 DC20_00465   Rufibacter tibetensis strain 1351 ALJ01084.1     12
 A4V00_07760   Ruminiclostridium sp. KB18 ANU53929.1     12
 RBI_I00435   Ruminococcus bicirculans 80/3 CCO04163.1     12
 Runsl_5735   Runella slithyformis DSM 19594 AEI52020.1     12
 Sde_0598 (Arb43H)   Saccharophagus degradans 2-40 ABD79862.1 Q21N67   12
 Sde_1655 (Arb43I)   Saccharophagus degradans 2-40 ABD80915.1 Q21K64   12
 AO058_06975   Salegentibacter sp. T436 APS38645.1     12
 AO058_07135   Salegentibacter sp. T436 APS38672.1     12
 Sked_21180   Sanguibacter keddieii DSM 10542 ACZ22038.1 D1BHW8   12
 Sked_20520   Sanguibacter keddieii DSM 10542 ACZ21974.1 D1BHQ4   12
 SCIP_1188   Scardovia inopinata JCM 12537 BAR07255.1     12
 SOCE26_001300   Sorangium cellulosum So ce26 AUX38752.1     12
 SpiGrapes_1804   Sphaerochaeta pleomorpha str. Grapes AEV29600.1     12
 Sph21_2647   Sphingobacterium sp. 21 ADZ79196.1     12
 Sph21_2653   Sphingobacterium sp. 21 ADZ79202.1     12
 BN1088_1430379   Sphingobacterium sp. PM2-P1-29 CDS91975.1     12
 BN1088_1430453   Sphingobacterium sp. PM2-P1-29 CDS92049.1     12
 GH43A19   Sphingobacterium sp. TN19 ACX30649.1 D8L2X9   12
 SJA_C2-02360 (XynB)   Sphingobium japonicum UT26S UT26S (= NBRC 101211) BAI98599.1 D4Z7Y0   12
 K663_01060   Sphingobium sp. MI1205 AMK16605.1     12
 BSY17_3564   Sphingobium sp. RAC03 AOF94978.1     12
 TZ53_09705   Sphingobium sp. YBL2 AJR26300.1     12
 YGS_C2P0910   Sphingobium sp. YG1 BBD02896.1     12
 A6768_02665   Sphingobium yanoikuyae S72 ATI79016.1     12
 A6768_12765   Sphingobium yanoikuyae S72 ATI83297.1     12
 BV87_09920   Sphingobium yanoikuyae SHJ ATP18685.1     12
 TS85_11255   Sphingomonas hengshuiensis WHSC-8 AJP74447.1     12
 AWL63_09465   Sphingomonas panacis DCY99 AOH84161.1     12
 NX02_07595   Sphingomonas sanxanigenens DSM 19645 = NX02 AHE53244.1     12
 CVN68_09105   Sphingomonas sp. Cra20 ATY32112.1     12
 AV944_11925   Sphingomonas sp. LK11 APX66421.1     12
 BXU08_08465   Sphingomonas sp. LM7 AQR73665.1     12
 MC45_12705   Sphingomonas taxi ATCC 55669 AIT07089.1     12
 BWQ93_10720   Sphingopyxis sp. QXT-31 AQA00798.1     12
 Slin_1423   Spirosoma linguale DSM 74 ADB37473.1 D2QMY9   12
 SD10_01815   Spirosoma radiotolerans DG5A AKD53825.1     12
 CWM47_18485   Spirosoma sp. HA7 AUD07371.1     12
 B7H26_11395   Stenotrophomonas maltophilia AB550 AWB78505.1     12
 SMD_2233 (XynB)   Stenotrophomonas maltophilia D457 CCH12774.1     12
 YH67_10540   Stenotrophomonas maltophilia ISMMS2 ALA86681.1     12
 YH68_10540   Stenotrophomonas maltophilia ISMMS2R ALA90637.1     12
 DX03_09880   Stenotrophomonas rhizophila DSM 14405 AHY58977.1     12
 BAY15_2020   Stenotrophomonas rhizophila QL-P4 AOA72454.1     12
 AXG53_00475   Stenotrophomonas sp. KCTC 12332 YM1 AMJ58542.1     12
 C7M71_009150   Streptacidiphilus sp. DSM 106435 AXI77583.1     12
 BTR42_08375   Streptococcus gallolyticus subsp. gallolyticus DSM 16831 AQP42647.1     12
 Spaf_1780   Streptococcus parasanguinis FW213 AFJ26729.1     12
 DMT42_32550   Streptomyces actuosus ATCC 25421 AWT46561.1     12
 DMT42_37190   Streptomyces actuosus ATCC 25421 AWT47330.1     12
 SBI_09922   Streptomyces bingchenggensis BCW-1 ADI13040.1 D7CDJ8   12
 SCO0118 or SCJ11.47   Streptomyces coelicolor A3(2) CAB52932.1
NP_624458.1
Q9RI60   12
 TU94_03450   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP00691.1     12
 SGLAU_05460   Streptomyces glaucescens GLA.O AIR97118.1     12
 SHJG_2787 (fragment)   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY88061.1     12
 SHJGH_2551 (fragment)   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF62217.1     12
 SHL15_1337   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO92507.1     12
 ABB07_01170   Streptomyces incarnatus NRRL 8089 AKJ08698.1     12
 Sle_62040   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR65659.1     12
 SLCG_1545 (fragment)   Streptomyces lincolnensis LC-G AXG52700.1     12
 SLCG_1545 (fragment)   Streptomyces lincolnensis LC-G AXG52700.1     12
 SLINC_8187   Streptomyces lincolnensis NRRL 2936 ANS70411.1     12
 SLINC_8279   Streptomyces lincolnensis NRRL 2936 ANS70503.1     12
 SLINC_1553   Streptomyces lincolnensis NRRL 2936 ANS63777.1     12
 SLIV_37325   Streptomyces lividans TK24 AIJ18335.1     12
 SNOD_31970   Streptomyces nodosus ATCC 14899 AJE44102.1     12
 Sfla_0360   Streptomyces pratensis ATCC 33331 ADW01826.1 C9N8E8   12
 TUE45_01764 (Xynb_1)   Streptomyces reticuli CUW27051.1     12
 A4G23_00448 (Xynb_1)   Streptomyces rubrolavendulae MJM4426 AOT57658.1     12
 SCAB_86491   Streptomyces scabiei 87.22 CBG75590.1 C9Z369   12
 SAMN05428941_0171   Streptomyces sp. 2114.2 SDS26986.1     12
 SAMN05444521_0297   Streptomyces sp. 3214.6 SHH37594.1     12
 ASR50_27450   Streptomyces sp. 4F ALV52787.1     12
 C2142_36730   Streptomyces sp. CB01881 AUY53506.1     12
 NI25_00470   Streptomyces sp. CCM_MD2014 AIV32177.1     12
 AS200_05360   Streptomyces sp. CdTB01 ALV31539.1     12
 AA958_29795   Streptomyces sp. CNQ-509 AKH85723.1     12
 SAM9427_28835   Streptomyces sp. ETH9427 AXI89335.1     12
 C1703_36995 (Xynb4)   Streptomyces sp. Go-475 AXE90647.1     12
 C1703_35930 (Xynb3)   Streptomyces sp. Go-475 AXE90435.1     12
 DVK44_08215   Streptomyces sp. GSSD-12 AXG77685.1     12
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