Glycoside Hydrolase Family 42

Activities in Familyβ-galactosidase (EC 3.2.1.23); α-L-arabinopyranosidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteIdentification of the catalytic residues in doi:10.1016/j.febslet.2007.04.053
External resourcesCAZypedia;
Statistics GenBank accession (2361); Uniprot accession (355); PDB accession (16); 3D entries (9); cryst (1)
All (2302) Archaea (9) Bacteria (2287) Eukaryota (5) unclassified (1) Structure (9 - 1 cryst) Characterized (65)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-galactosidase (BgaH) 3.2.1.23 Haloferax lucentense SB1 AAB40123.2 P94804  
 β-galactosidase (Bga;Hlac_2868) 3.2.1.23 Halorubrum lacusprofundi ATCC 49239 ACM58428.1 B9LW38  
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-galactosidase (GalB;LacB;Bgly;Aaci_2891) 3.2.1.23 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV59895.1
AAZ81841.1
ABI84370.1
C8WV58
Q06GJ1
 
 β-galactosidase 3.2.1.23 Arthrobacter sp. 32c ACU00913.1 C7ASJ5  
 β-galactosidase 12 (LacG) (possible fragment) 3.2.1.23 Arthrobacter sp. B7 AAA75601.1 Q44233  
 β-galactosidase (GalB) 3.2.1.23 Arthrobacter sp. ON14 ADJ18282.1 D9IU57  
 β-galactosidase (BgaB) 3.2.1.23 Bacillus circulans G1 AAA22260.1 Q45093  
 β-galactosidase (Bcα-β-Gal) 3.2.1.23 Bacillus circulans subsp. alkalophilus     3TTS[B,C,D,E,F]
3TTY[A,B,C,D,E,F]
3TTS[A]
 β-galactosidase (LacZ) 3.2.1.23 Bacillus coagulans DSM 1 ADF47156.1 D5JGG0  
 β-galactosidase (LacA;BLi04277;BL00264) 3.2.1.23 Bacillus licheniformis DSM 13 = ATCC 14580 AAU43090.1
AAU25712.1
ACP63807.1
Q65CX4  
 β-galactosidase (BglZQ) 3.2.1.23 Bacillus licheniformis ZQ1-8 AHW49175.1    
 β-galactosidase (YesZ;BSU07080) 3.2.1.23 Bacillus subtilis subsp. subtilis str. 168 CAB12527.1
AIY91999.1
AQR80664.1
AQR84877.1
NP_388589.1
O31529  
 β-galactosidase (LacA;YvfN;BSU34130) 3.2.1.23 Bacillus subtilis subsp. subtilis str. 168 CAB15418.1
AIY94732.1
AQR83448.1
AQR87663.1
CAB08008.1
NP_391293.1
O07012  
 β-galactosidase (BgalII) 3.2.1.23 Bifidobacterium adolescentis DSM 20083 AAR24113.1 Q5J883 5VYM[A,B]
 β-galactosidase (Bg42-106) 3.2.1.23 Bifidobacterium animalis B106 AGH68883.1    
 β-1,6/β-1,3-galactosidase (BlGal42A;Balac_0484) (Gal42A) 3.2.1.23 Bifidobacterium animalis subsp. lactis Bl-04 ACS45863.1 C6A6W5 4UNI[A,B,C]
4UOQ[A,B,C]
4UOZ[A,B,C]
 α-L-arabinopyranosidase (Balac_0053) 3.2.1.- Bifidobacterium animalis subsp. lactis Bl-04 ACS45449.1 C6A5Q1 5XB7[A,B,C,D,E,F]
 β-galactosidase P2 (BbgII) 3.2.1.23 Bifidobacterium bifidum NCIMB 41171 ABP87597.1 A5A2I5  
 β-galactosidase (BbgII;LacZ2;BBIF_1313) 3.2.1.23 Bifidobacterium bifidum S17 ADO53518.1 E3EPA1 4UCF[A,B,C]
4UZS[A,B,C]
 β-galactosidase (Bgal;GalA;LacA) 3.2.1.23 Bifidobacterium breve ATCC 15698 / B24 AAU00556.1 Q68GW3  
 β-galactosidase (GalG;Lacz4;Bbr_0420_galG;Bbr_0420) 3.2.1.23 Bifidobacterium breve UCC2003 ABE95118.1
ADO51667.1
   
 β-galactosidase (GosG;Lacz5;Bbr_0529_gosG;Bbr_0529) 3.2.1.23 Bifidobacterium breve UCC2003 ABE95226.1    
 β-1,4-galactosidase (Bbry_0422) 3.2.1.23 Bifidobacterium breve Yakult BAR71185.1    
 β-galactosidase (LacA1;BLD_0926) 3.2.1.23 Bifidobacterium longum DJO10A ACD98372.1 B3DTA3  
 β-galactosidase 42A (Blon_2016) (Bga42A) 3.2.1.23 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53083.1 B7GUD7  
 β-galactosidase 42B (Blon_2123) (Bga42B) 3.2.1.23 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53184.1 B7GUN8  
 β-galactosidase 42C (Blon_2416) (Bga42C) 3.2.1.23 Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53470.1 B7GNW4  
 β-galactosidase (INF1) 3.2.1.23 Bifidobacterium longum subsp. infantis DSM20088 CAC14567.1 Q9F4C8  
 β-galactosidase III (β-GalIII) 3.2.1.23 Bifidobacterium longum subsp. infantis HL96 AAL02053.1 Q93GI5  
 β-galactosidase (BgaA) 3.2.1.23 Caldicellulosiruptor 14B CAA10365.1    
 β-galactosidase (Csac_1018) 3.2.1.23 Caldicellulosiruptor saccharolyticus DSM 8903 ABP66632.1 A4XI97  
 β-galactosidase (BgaA) 3.2.1.23 Caldicellulosiruptor sp. YI5 ABA18805.1 Q0R0N2  
 β-galactosidase (BgaB) 3.2.1.23 Carnobacterium maltaromaticum AAF16519.1 Q9RFN0  
 β-galactosidase / α-L-arabinopyranosidase (BgaA) 3.2.1.23
3.2.1.-
Clostridium cellulovorans AAN05452.1 Q8GEE3  
 β-galactosidase (Pbg) 3.2.1.23 Clostridium perfringens BAA08485.1
CAA66274.1
Q59312  
 β-galactosidase (Dgeo_2829) 3.2.1.23 Deinococcus geothermalis DSM 11300 ABF44258.1
YP_594332.1
Q1J2M6  
 β-galactosidase / exo-β-1,4-galactanase (GanB;LacB;Dda3937_02393) 3.2.1.23 Dickeya dadantii 3937 ADM99399.1    
 β-galactosidase (Dtur_0505) 3.2.1.23 Dictyoglomus turgidum DSM 6724 ACK41798.1 B8E215  
 β-galactosidase I (BgaB) 3.2.1.23 Geobacillus stearothermophilus KVE39 AAA22262.1 P19668  
 β-galactosidase (GanB;Gan42B) (intracellular) 3.2.1.23 Geobacillus stearothermophilus T-6 AEH26455.1   4OIF[A,B,C]
4OJY[A,B,C]
5DFA[A,B,C]
 β-galactosidase (thermostable) 3.2.1.23 Geobacillus thermocatenulatus KNOUC105 AAW56416.1 Q5I201  
 β-galactosidase (GalC168) 3.2.1.23 Isoptericola sp. 168 ACV30341.1 C7T4Z3  
 β-galactosidase (BgaB) 3.2.1.23 Klebsiella pneumoniae 285 AEA30144.1    
 β-galactosidase (LacZ) 3.2.1.23 Lactobacillus acidophilus ATCC 4356 ACC38288.1 Q5FJ41  
 β-galactosidase (LacA) 3.2.1.23 Lactobacillus acidophilus FUA3191 CAZ66938.1 C6H178  
 β-galactosidase (LacA;LBA1364) 3.2.1.23 Lactobacillus acidophilus NCFM AAV43189.1 Q5FJD5  
 β-galactosidase (LacZ;LBA1462) 3.2.1.23 Lactobacillus acidophilus NCFM AAV43283.1
CAN87410.1
Q5FJ41  
 β-galactosidase (bg42-164) 3.2.1.23 Lactobacillus sp. B164 AFC88544.1    
 β-galactosidase (BgaP1) 3.2.1.23 Paenibacillus sp. K1 ACE62913.1 B3VBH7  
 β-galactosidase (BgaP) 3.2.1.23 Planococcus sp. L4 ABI64125.1 Q09HN2 cryst
 β-galactosidase (BgaA) 3.2.1.23 Planococcus sp. SOS Orange AAF75984.1 Q9KI47  
 β-galactosidase (Achl_3125) 3.2.1.23 Pseudarthrobacter chlorophenolicus A6 ACL41086.1 B8HFB8  
 β-galactosidase (R-β-Gal) 3.2.1.23 Rahnella sp. R3 AJC52391.1   5E9A[A,B,C,D,E,F]
 β-galactosidase (BgalC;TM1195) 3.2.1.23 Thermotoga maritima MSB8 AAD36270.1
AAA50596.1
AGL50126.1
AHD18898.1
AKE28971.1
NP_229000.1
Q56306
Q9X0S2
 
 β-galactosidase (BgalB;TM0310) 3.2.1.23 Thermotoga maritima MSB8 AAD35398.1
AGL49234.1
AHD17926.1
AKE28111.1
NP_228122.1
Q9WYE6  
 β-galactosidase (Tnap_1577) 3.2.1.23 Thermotoga naphthophila RKU-10 ADA67652.1 D2C4J8  
 β-galactosidase (BgalA) 3.2.1.23 Thermotoga neapolitana AAC24217.1 O85248  
 β-galactosidase (BgaA) (fragment) 3.2.1.23 Thermus oshimai DSM 12092 ACV87364.1 C9EF70  
 β-galactosidase (A4-β-Gal) 3.2.1.23 Thermus sp. A4 BAA28362.1 O69315 1KWG[A]
1KWK[A]
 β-galactosidase (BgaA) 3.2.1.23 Thermus sp. IB-21 AAN05443.1 Q8GEA9  
 β-galactosidase 3.2.1.23 Thermus sp. T2 CAB07810.1 O54315  
 β-galactosidase 3.2.1.23 Thermus thermophilus KNOUC112 ABI35985.1 Q0GA06  
 β-galactosidase (Zd410) 3.2.1.23 uncultured bacterium ADD69785.1 D4NYL2  
 β-galactosidase (Gal308) (thermostable) (fragment) 3.2.1.23 uncultured bacterium AFD21844.1    
 β-galactosidase (BgaP412) 3.2.1.23 uncultured bacterium AFD29748.1    
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