Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17817); Uniprot accession (2560); PDB accession (106); 3D entries (34); cryst (4)
All (16969) Archaea (94) Bacteria (15784) Eukaryota (990) Viruses (1) unclassified (100) Structure (34 - 4 cryst) Characterized (295)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 THITE_2119055   Thielavia terrestris NRRL 8126 AEO69052.1    
 THITE_122652   Thielavia terrestris NRRL 8126 AEO70559.1    
 THITE_2107118 (fragment)   Thielavia terrestris NRRL 8126 AEO62672.1    
 THITE_2107120 (fragment)   Thielavia terrestris NRRL 8126 AEO62673.1    
 THITE_2108759 (fragment)   Thielavia terrestris NRRL 8126 AEO63458.1    
 THITE_125239   Thielavia terrestris NRRL 8126 AEO68026.1    
 THITE_2031888 (short fragment)   Thielavia terrestris NRRL 8126 AEO69750.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55676.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55594.1    
 secreted protein (fragment)   Thraustotheca clavata ATCC 34112 AIG55725.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55751.1    
 β-glucosidase (TkBgl3A) (Bgl3A) 3.2.1.21 Trichoderma koningiopsis FCD3-1 AIB10099.1    
 β-xylosidase (Bxl1) (Xyl3A) 3.2.1.37 Trichoderma reesei CAA93248.1
CAW52645.1
CBC23920.1
Q92458 5A7M[A,B]
5AE6[A,B]
 TRIREDRAFT_79669 (Nag3)   Trichoderma reesei QM6a EGR47352.1    
 β-glucosidase (Cel3B)   Trichoderma reesei QM6A AAP57755.1
ABE16061.1
Q7Z9M5  
 Cel3c (Cel3C)   Trichoderma reesei QM6A AAP57756.1
ABH82050.1
Q7Z9M4  
 Cel3d (fragment) (Cel3D)   Trichoderma reesei QM6A AAP57759.1 Q7Z9M1  
 Cel3e (Cel3E)   Trichoderma reesei QM6A AAP57760.1
ACH26685.1
Q7Z9M0  
 β-glucosidase 1 (Bgl1;Bgl-1;TrBGL1) (Cel3A) 3.2.1.21 Trichoderma reesei QM9414 AAA18473.1 Q12715 3ZYZ[A]
4I8D[A,B]
 β-glucosidase (Cel3D)   Trichoderma reesei QM9414 BAP59014.1    
 β-glucosidase (Cel3G)   Trichoderma reesei QM9414 BAP59015.1    
 ORF   Trichoderma reesei QM9414 BAP59016.1    
 β-glucosidase   Trichoderma sp. SSL ACH92574.1 B5TYI5  
 β-glucosidase (epB-BGL) 3.2.1.21 Trichoderma sp. W63 / CGMCC 5209 AJC01624.1    
 β-N-acetylglucosaminidase (Nag3)   Trichoderma virens ACH72647.1 B5M694  
 xln   Trichoderma virens AMP44571.1    
 β-glucosidase I (Bgl1;BGL1;VbglI) 3.2.1.21 Trichoderma viride AS 3.3711 ACS93768.1 C6GGC9  
 β-glucosidase (Bgl1)   Trichoderma viride AS 3.3711 AAQ76093.1 Q6UJY0  
 β-glucosidase   Trigonella foenum-graecum AQY19164.1    
 β-glucosidase   Trigonella foenum-graecum AQY19164.1    
 β-D-glucan exohydrolase   Triticum aestivum AAM13694.1 Q8RWR5  
 unnamed protein product   Triticum aestivum CAW52652.1
CBC23934.1
CBD35273.1
   
 unnamed protein product   Triticum aestivum CAW52653.1
CBC23936.1
CBD35274.1
   
 ORF (fragment)   Triticum aestivum BAD06320.1 Q75RZ3  
 TRAES_3BF074800100CFD_c1   Triticum aestivum CDM84404.1    
 β-glucosidase 3.2.1.21 Tropaeolum majus CAA07070.1 O82074  
 β-glucosidase, partial (fragment)   uncultured fungus AKI33967.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33959.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33966.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33971.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33963.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33964.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33958.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33969.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33965.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33962.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33960.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33968.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33970.1    
 β-glucosidase, partial (fragment)   uncultured fungus AKI33961.1    
 β-glucosidase, partial (fragment)   uncultured fungus ARQ32329.1    
 β-glucosidase, partial (fragment)   uncultured fungus ARQ32330.1
ARU79426.1
   
 β-glucosidase, partial (fragment)   uncultured fungus ARQ32328.1    
 ORF (fragment)   uncultured fungus ARU79444.1    
 ORF (fragment)   uncultured fungus ARU79429.1    
 ORF (fragment)   uncultured fungus ARU79425.1    
 ORF (fragment)   uncultured fungus ARU79433.1    
 ORF (fragment)   uncultured fungus ARU79445.1    
 ORF (fragment)   uncultured fungus ARU79434.1    
 β-glucosidase (Bgl1) 3.2.1.21 Uromyces viciae-fabae CAE01320.1 Q70KQ7  
 UBRO_06098   Ustilago bromivora UB2112 SAM84689.1    
 UBRO_08622   Ustilago bromivora UB2112 SAM86201.1    
 UBRO_00702   Ustilago bromivora UB2112 SAM69052.1    
 UBRO_08981   Ustilago bromivora UB2112 SAM86449.1    
 β-glucosidase (UeBgl3A) (Bgl3A) 3.2.1.21 Ustilago esculenta NBRC 9887 BAK61808.1    
 UM04032.1 (Umay-Bgl101)   Ustilago maydis 521 EAK85129.1    
 β-glucosidase 1 (Bgl1)   Verticillium longisporum AKD01707.1    
 VIGAN_11078800 (Vigan.11g078800) (fragment)   Vigna angularis var. angularis BAU01534.1    
 VIGAN_10082600 (Vigan.10g082600)   Vigna angularis var. angularis BAT99397.1    
 VIGAN_08198200 (Vigan.08g198200)   Vigna angularis var. angularis BAT95286.1    
 VIGAN_08325800 (Vigan.08g325800)   Vigna angularis var. angularis BAT96337.1    
 VIGAN_08050800 (Vigan.08g050800)   Vigna angularis var. angularis BAT93952.1    
 VIGAN_05107000 (Vigan.05g107000)   Vigna angularis var. angularis BAT87677.1    
 VIGAN_05184700 (Vigan.05g184700)   Vigna angularis var. angularis BAT88373.1    
 VIGAN_05016500 (Vigan.05g016500)   Vigna angularis var. angularis BAT86844.1    
 VIGAN_03168600 (Vigan.03g168600)   Vigna angularis var. angularis BAT81804.1    
 VIGAN_03057800 (Vigan.03g057800)   Vigna angularis var. angularis BAT80949.1    
 VIGAN_04389700 (Vigan.04g389700) (fragment)   Vigna angularis var. angularis BAT86261.1    
 VIGAN_04243300 (Vigan.04g243300)   Vigna angularis var. angularis BAT84947.1    
 VIGAN_02332800 (Vigan.02g332800)   Vigna angularis var. angularis BAT80327.1    
 VIGAN_01157100 (Vigan.01g157100)   Vigna angularis var. angularis BAT73993.1    
 VIGAN_04243100 (Vigan.04g243100)   Vigna angularis var. angularis BAT84946.1    
 VIGAN_03130600 (Vigan.03g130600)   Vigna angularis var. angularis BAT81557.1    
 VIGAN_02123100 (Vigan.02g123100)   Vigna angularis var. angularis BAT78542.1    
 VITISV_023986 (fragment)   Vitis vinifera CAN80947.1 A5BA78  
 VITISV_007589 (fragment)   Vitis vinifera CAN77623.1 A5C5J3  
 VITISV_033721 (fragment)   Vitis vinifera CAN72807.1 A5BX38  
 VITISV_030325   Vitis vinifera CAN78858.1 A5BC37  
 VITISV_027177   Vitis vinifera CAN63654.1 A5BMI5  
 VITISV_035506   Vitis vinifera CAN82161.1 A5AHE5  
 VITISV_033665   Vitis vinifera CAN81230.1 A5BKF4  
 β-glucosidase (Bgl;BGL-II) 3.2.1.21 Volvariella volvacea V14 AAG59831.1 Q9C3Z9  
 β-glucosidase   Wickerhamomyces anomalus MDD24 AFN27527.1    
 β-glucosidase 3.2.1.21 Wickerhamomyces anomalus VAR. ACETAETHERIUS CAA26662.1 P06835  
 glycoside hydrolase family 3 protein   Xanthophyllomyces dendrorhous CED83962.1    
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CED82386.1    
 glycoside hydrolase family 3 protein   Xanthophyllomyces dendrorhous CDZ97665.1    
 YALI0D18381g   Yarrowia lipolytica CLIB122 CAG81175.1 Q6C8M9  
 YALI0B14333g   Yarrowia lipolytica CLIB122 CAG83130.1 Q6CEN3  
 YALI0E20185g   Yarrowia lipolytica CLIB122 CAG79772.1 Q6C585  
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