Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (18266); Uniprot accession (2560); PDB accession (110); 3D entries (35); cryst (4)
All (17410) Archaea (95) Bacteria (16189) Eukaryota (1024) Viruses (1) unclassified (101) Structure (35 - 4 cryst) Characterized (296)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 11 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-xylosidase (Xyl1) 3.2.1.37 Fragaria x ananassa AAS17751.2
CAW96536.1
CAW96699.1
CAX01913.1
CAX07267.1
CBD30903.1
Q6RXY3  
 FcFDB1_03   Fusarium camptoceras NRRL 13381 AMB48849.1    
 FFUJ_02025   Fusarium fujikuroi IMI 58289 CCT61496.1    
 FFUJ_00469   Fusarium fujikuroi IMI 58289 CCT62926.1    
 FFUJ_00226   Fusarium fujikuroi IMI 58289 CCT63152.1    
 FFUJ_00166   Fusarium fujikuroi IMI 58289 CCT63210.1    
 FFUJ_03618   Fusarium fujikuroi IMI 58289 CCT66579.1    
 FFUJ_07959   Fusarium fujikuroi IMI 58289 CCT69025.1    
 FFUJ_05366   Fusarium fujikuroi IMI 58289 CCT69478.1    
 FFUJ_06106   Fusarium fujikuroi IMI 58289 CCT70761.1    
 FFUJ_06120   Fusarium fujikuroi IMI 58289 CCT70172.1    
 FFUJ_08900   Fusarium fujikuroi IMI 58289 CCT71060.1    
 FFUJ_12674   Fusarium fujikuroi IMI 58289 CCT72781.1    
 FFUJ_09224   Fusarium fujikuroi IMI 58289 CCT73941.1    
 FFUJ_10518   Fusarium fujikuroi IMI 58289 CCT75131.1    
 FFUJ_10785   Fusarium fujikuroi IMI 58289 CCT75117.1    
 FFUJ_11101   Fusarium fujikuroi IMI 58289 CCT75026.1    
 FFUJ_11227   Fusarium fujikuroi IMI 58289 CCT75186.1    
 FFUJ_11272   Fusarium fujikuroi IMI 58289 CCT75247.1    
 FFUJ_11626   Fusarium fujikuroi IMI 58289 CCT75598.1    
 FFUJ_12047   Fusarium fujikuroi IMI 58289 CCT75990.1    
 FFUJ_03399   Fusarium fujikuroi IMI 58289 CCT66374.1    
 FFUJ_10572   Fusarium fujikuroi IMI 58289 CCT74517.1    
 FFUJ_11863   Fusarium fujikuroi IMI 58289 CCT75821.1    
 FFUJ_03922   Fusarium fujikuroi IMI 58289 CCT64822.1    
 FFUJ_03852   Fusarium fujikuroi IMI 58289 CCT64887.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78442.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76070.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF74963.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86475.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76231.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF77881.1    
 FGRAMPH1_01T12759   Fusarium graminearum PH-1 SCB65805.1
CEF78182.1
   
 unnamed protein product   Fusarium graminearum PH-1 CEF78744.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79774.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72029.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72767.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF83026.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF84532.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85991.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85907.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF87331.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76727.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76991.1    
 FGRAMPH1_01T12819   Fusarium graminearum PH-1 SCB65807.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78397.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF71930.1    
 avenacinase-like protein   Gaeumannomyces avenae ATCC 15419 AAN39015.1 Q8J2P2  
 avenacinase I 3.2.1.- Gaeumannomyces graminis AAB09777.1 Q00903  
 avenacinase II (fragment) 3.2.1.- Gaeumannomyces graminis AAA63146.1 Q00902  
 avenacinase-like protein   Gaeumannomyces graminis var. graminis ATCC 12761 AAN39016.1 Q8J2P1  
 avenacinase-like protein   Gaeumannomyces tritici GGT CB1 AAN39017.1 Q8J2P0  
 avenacinase-like protein   Gaeumannomyces tritici GGT CH1 AAN39018.1 Q8J2N9  
 avenacinase-like protein   Gaeumannomyces tritici GGT M1 AAN39019.1 Q8J2N8  
 β-glucosidase (Bgl)   Glaciozyma antarctica PI12 AFK65507.1    
 unnamed protein product   Glycine max CAW52612.1
CAW52656.1
CAW96522.1
CAW96685.1
CAX01899.1
CAX07253.1
CBC23851.1
CBD30889.1
   
 unnamed protein product   Glycine max CAW52611.1
CAW96521.1
CAW96684.1
CAX01898.1
CAX07252.1
CBC23849.1
CBD30888.1
CBD33476.1
   
 unnamed protein product   Glycine max CAW52651.1
CBC23933.1
CBD35271.1
   
 unnamed protein product   Glycine max CAW52657.1
CAW96541.1
CAW96704.1
CAX01918.1
CAX07272.1
CBC23945.1
CBD30908.1
CBD33477.1
   
 unnamed protein product   Glycine max CBD33472.1    
 unnamed protein product   Glycine max CBD33473.1    
 unnamed protein product   Glycine max CBD33478.1    
 ORF (fragment)   Glycine max AAQ57197.1 Q6V491  
 β-glucosidase (fragment)   Glycine max AAD09291.1 Q9ZU04  
 β-glucosidase (Bgl;GmBGL) 3.2.1.21 Glycine max AIO11756.1    
 β-1,4-glucanase   Gossypium aridum AEP33579.1    
 β-1,4-glucanase   Gossypium armourianum AEP33575.1    
 BG   Gossypium barbadense ADZ16108.1    
 β-1,4-glucanase   Gossypium barbadense var. brasiliense AEP33571.1    
 β-1,4-glucanase   Gossypium barbadense var. brasiliense AEP33570.1    
 β-1,4-glucanase   Gossypium barbadense var. peruvianum AEP33573.1    
 β-1,4-glucanase   Gossypium barbadense var. peruvianum AEP33572.1    
 β-1,4-glucanase   Gossypium darwinii AEP33567.1    
 β-1,4-glucanase   Gossypium darwinii AEP33566.1    
 β-1,4-glucanase   Gossypium davidsonii AEP33577.1    
 β-1,4-glucanase   Gossypium gossypioides AEP33580.1    
 β-1,4-glucanase   Gossypium harknessii AEP33576.1    
 BG   Gossypium herbaceum subsp. africanum ADZ16109.1    
 β-glucosidase (BG;GhBH)   Gossypium hirsutum AAZ15705.1
ADZ16111.1
Q4F885  
 ORF   Gossypium hirsutum ACALA MAXXA AAQ17461.1 Q7XAS3  
 β-1,4-glucanase   Gossypium hirsutum subsp. latifolium AEP33574.1    
 β-1,4-glucanase   Gossypium klotzschianum AEP33578.1    
 β-1,4-glucanase   Gossypium laxum AEP33561.1    
 β-1,4-glucanase   Gossypium lobatum AEP33581.1    
 β-1,4-glucanase   Gossypium mustelinum AEP33565.1    
 β-1,4-glucanase   Gossypium mustelinum AEP33564.1    
 BG   Gossypium raimondii ADZ16110.1    
 β-1,4-glucanase   Gossypium schwendimanii AEP33562.1    
 β-1,4-glucanase   Gossypium thurberi AEP33560.1    
 β-1,4-glucanase   Gossypium tomentosum AEP33569.1    
 β-1,4-glucanase   Gossypium tomentosum AEP33568.1    
 β-1,4-glucanase   Gossypium trilobum AEP33582.1    
 β-1,4-glucanase   Gossypium turneri AEP33563.1    
 ORF (fragment)   Heterocapsa triquetra AAW79377.1 Q5ENL6  
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09944.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09913.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09936.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09916.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09947.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09912.1    
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