Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17231); Uniprot accession (2560); PDB accession (105); 3D entries (33); cryst (4)
All (16380) Archaea (94) Bacteria (15236) Eukaryota (949) Viruses (1) unclassified (100) Structure (33 - 4 cryst) Characterized (293)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 unnamed protein product   Fusarium graminearum PH-1 CEF79774.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72029.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72767.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF83026.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF84532.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85991.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85907.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF87331.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76727.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76991.1    
 FGRAMPH1_01T12819   Fusarium graminearum PH-1 SCB65807.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78397.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF71930.1    
 avenacinase-like protein   Gaeumannomyces avenae ATCC 15419 AAN39015.1 Q8J2P2  
 avenacinase I 3.2.1.- Gaeumannomyces graminis AAB09777.1 Q00903  
 avenacinase II (fragment) 3.2.1.- Gaeumannomyces graminis AAA63146.1 Q00902  
 avenacinase-like protein   Gaeumannomyces graminis var. graminis ATCC 12761 AAN39016.1 Q8J2P1  
 avenacinase-like protein   Gaeumannomyces tritici GGT CB1 AAN39017.1 Q8J2P0  
 avenacinase-like protein   Gaeumannomyces tritici GGT CH1 AAN39018.1 Q8J2N9  
 avenacinase-like protein   Gaeumannomyces tritici GGT M1 AAN39019.1 Q8J2N8  
 β-glucosidase (Bgl)   Glaciozyma antarctica PI12 AFK65507.1    
 unnamed protein product   Glycine max CAW52612.1
CAW52656.1
CAW96522.1
CAW96685.1
CAX01899.1
CAX07253.1
CBC23851.1
CBD30889.1
   
 unnamed protein product   Glycine max CAW52611.1
CAW96521.1
CAW96684.1
CAX01898.1
CAX07252.1
CBC23849.1
CBD30888.1
CBD33476.1
   
 unnamed protein product   Glycine max CAW52651.1
CBC23933.1
CBD35271.1
   
 unnamed protein product   Glycine max CAW52657.1
CAW96541.1
CAW96704.1
CAX01918.1
CAX07272.1
CBC23945.1
CBD30908.1
CBD33477.1
   
 unnamed protein product   Glycine max CBD33472.1    
 unnamed protein product   Glycine max CBD33473.1    
 unnamed protein product   Glycine max CBD33478.1    
 ORF (fragment)   Glycine max AAQ57197.1 Q6V491  
 β-glucosidase (fragment)   Glycine max AAD09291.1 Q9ZU04  
 β-glucosidase (Bgl;GmBGL) 3.2.1.21 Glycine max AIO11756.1    
 β-1,4-glucanase   Gossypium aridum AEP33579.1    
 β-1,4-glucanase   Gossypium armourianum AEP33575.1    
 BG   Gossypium barbadense ADZ16108.1    
 β-1,4-glucanase   Gossypium barbadense var. brasiliense AEP33571.1    
 β-1,4-glucanase   Gossypium barbadense var. brasiliense AEP33570.1    
 β-1,4-glucanase   Gossypium barbadense var. peruvianum AEP33573.1    
 β-1,4-glucanase   Gossypium barbadense var. peruvianum AEP33572.1    
 β-1,4-glucanase   Gossypium darwinii AEP33567.1    
 β-1,4-glucanase   Gossypium darwinii AEP33566.1    
 β-1,4-glucanase   Gossypium davidsonii AEP33577.1    
 β-1,4-glucanase   Gossypium gossypioides AEP33580.1    
 β-1,4-glucanase   Gossypium harknessii AEP33576.1    
 BG   Gossypium herbaceum subsp. africanum ADZ16109.1    
 β-glucosidase (BG;GhBH)   Gossypium hirsutum AAZ15705.1
ADZ16111.1
Q4F885  
 ORF   Gossypium hirsutum ACALA MAXXA AAQ17461.1 Q7XAS3  
 β-1,4-glucanase   Gossypium hirsutum subsp. latifolium AEP33574.1    
 β-1,4-glucanase   Gossypium klotzschianum AEP33578.1    
 β-1,4-glucanase   Gossypium laxum AEP33561.1    
 β-1,4-glucanase   Gossypium lobatum AEP33581.1    
 β-1,4-glucanase   Gossypium mustelinum AEP33565.1    
 β-1,4-glucanase   Gossypium mustelinum AEP33564.1    
 BG   Gossypium raimondii ADZ16110.1    
 β-1,4-glucanase   Gossypium schwendimanii AEP33562.1    
 β-1,4-glucanase   Gossypium thurberi AEP33560.1    
 β-1,4-glucanase   Gossypium tomentosum AEP33569.1    
 β-1,4-glucanase   Gossypium tomentosum AEP33568.1    
 β-1,4-glucanase   Gossypium trilobum AEP33582.1    
 β-1,4-glucanase   Gossypium turneri AEP33563.1    
 ORF (fragment)   Heterocapsa triquetra AAW79377.1 Q5ENL6  
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09944.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09913.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09936.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09916.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09947.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09912.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09938.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09910.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09920.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09923.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09932.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09930.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09915.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09943.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09935.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09927.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09905.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09946.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09922.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09948.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09911.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09929.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09931.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09919.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09926.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09949.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09906.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09918.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09914.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09921.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09934.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09940.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09942.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09928.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09908.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09925.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09937.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09950.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09945.1    
 H-antigen precursor, partial (fragment)   Histoplasma capsulatum ASU09907.1    
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