Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (18870); Uniprot accession (2560); PDB accession (114); 3D entries (37); cryst (4)
All (18004) Archaea (96) Bacteria (16777) Eukaryota (1029) Viruses (1) unclassified (101) Structure (37 - 4 cryst) Characterized (297)
| 1 | ... | 149 | 150 | 151 | 152 | 153 | 154 | 155 | 156 | 157 | ... | 168 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-glucosidase, glycoside hydrolase family GH3   uncultured bacterium AOE06909.1    
 β-hexosaminidase (fragment)   uncultured bacterium AOS48146.1    
 ORF (fragment)   uncultured bacterium APO29522.1    
 ORF (fragment)   uncultured bacterium APO28697.1    
 ORF (fragment)   uncultured bacterium APO28663.1    
 GH3   uncultured bacterium AQQ74489.1    
 GH3   uncultured bacterium AQQ74457.1    
 Periplasmic β-glucosidase precursor   uncultured bacterium SIP56336.1    
 Periplasmic β-glucosidase precursor   uncultured bacterium SIP56417.1    
 Periplasmic β-glucosidase precursor   uncultured bacterium SIP56440.1    
 Periplasmic β-glucosidase precursor   uncultured bacterium SIP56345.1    
 Periplasmic β-glucosidase precursor   uncultured bacterium SIP56394.1    
 β-glucosidase, partial (fragment)   uncultured bacterium ARR75609.1    
 D79   uncultured bacterium ART37136.1    
 glycosyl hydrolase, partial   uncultured bacterium ASV47093.1    
 glycoside hydrolase   uncultured bacterium ASV46736.1    
 β-glucosidase, partial (fragment)   uncultured bacterium AUB45103.1    
 β-glucoside phosphorylase BglP 2.4.1.- uncultured bacterium AUG44408.1
AUG44422.1
  5VQD[A]
5VQE[A]
 β-glucosidase YNBG3, partial   uncultured bacterium AUR45174.1    
 β-glucosidase (PB16D15)   uncultured bacterium ADF43753.1 D5LNJ0  
 β-glucosidase (Bgl2;BGL4A6-ORF17) 3.2.1.21 uncultured bacterium AEV59721.1    
 β-glucosidase (Bgl1;BGL02B4-ORF21) 3.2.1.21 uncultured bacterium AEV59720.1    
 BGL04B5-ORF15 (Bgl4)   uncultured bacterium AEV59733.1    
 β-glucosidase (UmBgl3A) 3.2.1.21 uncultured bacterium AAZ32298.1 Q461Q3  
 β-glucosidase (UmBgl3B;RG2) 3.2.1.21 uncultured bacterium ABA42186.1 Q3HXC2  
 β-glucosidase (UmBgl3C;RG3) 3.2.1.21 uncultured bacterium ABA42187.1 Q3HXC1  
 BGL4 (Bgl6)   uncultured bacterium AFH08276.1    
 β-glucosidase (BGL5;Bgl7O16) 3.2.1.21 uncultured bacterium AFH08277.1    
 BGL6 (Bgl8)   uncultured bacterium AFH08278.1    
 β-glucosidase (BGL7;Bgl9) 3.2.1.21 uncultured bacterium AFH08279.1    
 BGL8 (Bgl10)   uncultured bacterium AFH08280.1    
 β-glucosidase (BGL9;Bgl11) 3.2.1.21 uncultured bacterium AFH08281.1    
 BGL2 (Bgl2) (partial)   uncultured bacterium AFH08274.1    
 endo-1,4-β-glucanase (UmBgl3A)   uncultured bacterium ABB51613.1 Q308B5  
 β-glucosidase   uncultured bacterium AFU63316.1    
 β-glucosidase   uncultured bacterium AFU63317.1    
 β-glucosidase (UmBgl3D) 3.2.1.21 uncultured bacterium ABE60716.1 Q1PDD6  
 orf101   uncultured bacterium AGD93197.1    
 BgGlu1-1GH3_2   uncultured bacterium AGN70394.1    
 BgGlu1-1GH3   uncultured bacterium AGN70393.1    
 β-glucosidase (RG11) 3.2.1.21 uncultured bacterium ABI94087.1 Q06B36  
 β-glucosidase (RG12) 3.2.1.21 uncultured bacterium ABI94088.1 Q06B35  
 β-glucosidase (RG14) 3.2.1.21 uncultured bacterium ABI94089.1 Q06B34  
 β-glucosidase (RG20) 3.2.1.21 uncultured bacterium ABI94090.1 Q06B33  
 β-glucosidase (RG25) 3.2.1.21 uncultured bacterium ABI94091.1 Q06B32  
 MetaPbio_Contig3_70c--XOS   uncultured bacterium CCG34879.1    
 β-glucosidase 1-10 (Bgl1-10)   uncultured bacterium AHB24360.1    
 β-glucosidase 1-6 (Bgl1-6) (possible fragment)   uncultured bacterium AHB24361.1    
 β-glucosidase (AS-Esc6) 3.2.1.21 uncultured bacterium AHG23300.1    
 β-glucosidase (AmBGL17) 3.2.1.21 uncultured bacterium AHI85741.1    
 β-glucosidase (GHF3)   uncultured bacterium AGG23333.1    
 cellulase (Lc-CelI) (partial)   uncultured bacterium AHL27902.1    
 ORF (fragment)   uncultured bacterium AIA18570.1    
 β-glucosidase (BglucMM5.1;Bgluc5.1_1) (fragment)   uncultured bacterium AID58676.1    
 AS-Esc17   uncultured bacterium AIF34069.1    
 DDGL-7   uncultured bacterium AIY68304.1    
 glycosyl hydrolase family   uncultured bacterium 20 ALV86508.1    
 glycoside hydrolase family 3 protein   uncultured bacterium 253 ADC36136.1 E3T742  
 β-glucosidase (BglX) (fragment)   uncultured bacterium 5H7 ALG05359.1
ALG05361.2
   
 β-glucosidase (A1_GH3) 3.2.1.21 uncultured bacterium A1_9 AEW47937.1    
 ORF   uncultured bacterium Ad_095_K16_contig1 AIF25961.1    
 ORF   uncultured bacterium Ad_142_N07 AIF26131.1    
 AKSOIL_0254   uncultured bacterium BLR13 ACN58869.1 C0INI3  
 ORF   uncultured bacterium C2_50 AEW47950.1    
 glycosyl hydrolase family 3 N terminal domain-containing protein (fragment)   uncultured bacterium contig00003(2014) AIA99562.1    
 ORF (fragment)   uncultured bacterium contig00005(2014) AIA99566.1    
 ORF   uncultured bacterium contig00008(2014) AIA99596.1    
 ORF   uncultured bacterium contig00010(2014) AIA99571.1    
 ORF   uncultured bacterium contig00023(2014) AIA99588.1    
 ORF   uncultured bacterium contig00100(2014) AIA99581.1    
 ORF   uncultured bacterium contig00103(2014) AIA99599.1    
 ORF   uncultured bacterium contig00106(2014) AIA99602.1    
 ORF   uncultured bacterium contig00110(2014) AIA99610.1    
 ORF   uncultured bacterium contig00113(2014) AIA99613.1    
 ORF   uncultured bacterium Contig11 AHF25412.1    
 ORF (fragment)   uncultured bacterium Contig1135 AHF26863.1    
 ORF (fragment)   uncultured bacterium Contig115 AHF26464.1    
 ORF   uncultured bacterium Contig12 AHF24736.1    
 ORF   uncultured bacterium Contig13 AHF24668.1    
 ORF   uncultured bacterium Contig14 AHF25022.1    
 ORF   uncultured bacterium Contig14 AHF25020.1    
 ORF   uncultured bacterium Contig140 AHF23793.1    
 ORF (fragment)   uncultured bacterium Contig140 AHF23779.1    
 ORF   uncultured bacterium Contig1450 AHF24116.1    
 ORF   uncultured bacterium Contig15 AHF23870.1    
 ORF   uncultured bacterium Contig1500 AHF25322.1    
 ORF (fragment)   uncultured bacterium Contig1500 AHF25324.1    
 ORF   uncultured bacterium Contig1514 AHF25042.1    
 ORF   uncultured bacterium Contig1522a AHF23933.1    
 ORF   uncultured bacterium Contig1529 AHF24580.1    
 ORF   uncultured bacterium Contig1532b AHF23689.1    
 ORF   uncultured bacterium Contig16 AHF24000.1    
 ORF (fragment)   uncultured bacterium Contig16 AHF23977.1    
 ORF   uncultured bacterium Contig1604 AHF25260.1    
 ORF   uncultured bacterium Contig1753 AHF24972.1    
 ORF (fragment)   uncultured bacterium Contig1759 AHF23895.1    
 ORF (fragment)   uncultured bacterium Contig1759 AHF23896.1    
 ORF (fragment)   uncultured bacterium Contig1771_n_1784_cl AHF26358.1    
 ORF   uncultured bacterium Contig1777_n_1791_cl AHF26270.1    
 β-glucosidase 3.2.1.21 uncultured bacterium Contig178 AHF25279.1    
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