Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-); β-1,2-glucosidase (EC 3.2.1.-); β-1,3-glucosidase (EC 3.2.1.-); xyloglucan-specific exo-β-1,4-glucanase / exo-xyloglucanase (EC 3.2.1.155)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that some enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (36938); Uniprot accession (2560); PDB accession (177); 3D entries (53); cryst (4)
All (35969) Archaea (155) Bacteria (33882) Eukaryota (1822) Viruses (1) unclassified (109) Structure (53 - 4 cryst) Characterized (313)
| 1 | 2 |
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ASAC_1378   Acidilobus saccharovorans 345-15 ADL19783.1    
 Cmaq_1217   Caldivirga maquilingensis IC-167 ABW02044.1 A8ME38  
 Cmaq_1311   Caldivirga maquilingensis IC-167 ABW02138.1 A8M8R9  
 NFRAN_1601   Candidatus Nitrosocosmicus franklandus VFJ13923.1    
 DSAG12_01647   Candidatus Prometheoarchaeum syntrophicum MK-D1 QEE15820.1    
 CPM_1642   Cuniculiplasma divulgatum PM4 (=JCM 30641; =VKM B-2940) SJK85429.1    
 CSP5_1676   Cuniculiplasma divulgatum S5(T) (=JCM 30642; =VKM B-2941) SIM80601.1    
 HacjB3_02060   Halalkalicoccus jeotgali B3 ADJ13805.1 D8J5Z9  
 HacjB3_15155   Halalkalicoccus jeotgali B3 ADJ16410.1 D8J9S1  
 EFA46_010000   Halarchaeum sp. CBA1220 QLC34521.1    
 EFA46_010935 (fragment)   Halarchaeum sp. CBA1220 QLC35222.1    
 HAH_0924 (Bglx-1)   Haloarcula hispanica ATCC 33960 CGMCC 1.2049 AEM56542.1    
 HAH_1720 (Bglx-2)   Haloarcula hispanica ATCC 33960 CGMCC 1.2049 AEM57322.1    
 HAH_4339 (NagZ)   Haloarcula hispanica ATCC 33960 CGMCC 1.2049 AEM59010.1    
 HISP_16920   Haloarcula hispanica N601 AHB67706.1    
 HISP_04760   Haloarcula hispanica N601 AHB65348.1    
 HISP_08780   Haloarcula hispanica N601 AHB66088.1    
 rrnAC0173 (BglX-1)   Haloarcula marismortui ATCC 43049 AAV45239.1
QCP93018.1
Q5V5G3  
 rrnAC1113 (BglX-2)   Haloarcula marismortui ATCC 43049 AAV46070.1
QCP90833.1
Q5V332  
 SG26_12450   Haloarcula sp. CBA1115 AJF26480.1    
 SG26_00660   Haloarcula sp. CBA1115 AJF24341.1    
 SG26_16515   Haloarcula sp. CBA1115 AJF27220.1    
 G9465_07960   Haloarcula sp. JP-L23 QIO22276.1    
 G9465_13875   Haloarcula sp. JP-L23 QIO23381.1    
 BVU17_08295   Haloarcula taiwanensis AUG48874.1    
 HARCEL1_11985   Haloarculaceae archaeon HArcel1 AWB28724.1    
 HARCEL1_10310   Haloarculaceae archaeon HArcel1 AWB28071.1    
 HARCEL1_04830   Haloarculaceae archaeon HArcel1 AWB28637.1    
 HARCEL1_05365 (fragment)   Haloarculaceae archaeon HArcel1 AWB28642.1    
 HARCEL1_09785 (fragment)   Haloarculaceae archaeon HArcel1 AWB28696.1    
 HARCEL1_09015   Haloarculaceae archaeon HArcel1 AWB27841.1    
 Hhub_1804   Halobacterium hubeiense JI20-1 CQH52072.1    
 Hhub_4033   Halobacterium hubeiense JI20-1 CQH63296.1    
 HUG10_16340 (fragment)   Halobonum sp. Gai3-2 QLG29546.1    
 G3A49_13970   Haloferax alexandrinus wsp1 QIB79159.1    
 G3A49_13975   Haloferax alexandrinus wsp1 QIB79160.1    
 ABY42_15105   Haloferax gibbonsii ARA6 AKU09139.1    
 ABY42_10385   Haloferax gibbonsii ARA6 AKU08130.1    
 ABY42_10160   Haloferax gibbonsii ARA6 AKU08087.1    
 ABY42_10380   Haloferax gibbonsii ARA6 AKU08129.1    
 HfgLR_13170   Haloferax gibbonsii LR2-5 QOS12762.1    
 HfgLR_13420   Haloferax gibbonsii LR2-5 QOS12812.1    
 HfgLR_22535   Haloferax gibbonsii LR2-5 QOS13715.1    
 HfgLR_13165   Haloferax gibbonsii LR2-5 QOS12761.1    
 BM92_18860   Haloferax mediterranei ATCC 33500 AHZ24265.1    
 HFX_5029 (Amy6;GlyAHme) 3.2.1.- Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK20866.1
QCQ77294.1
   
 HVO_2087   Haloferax volcanii DS2 ADE03343.1 D4GUN5  
 HVO_2088 (XloA)   Haloferax volcanii DS2 ADE02994.1 D4GUN6  
 Hbor_33610   Halogeometricum borinquense DSM 11551 ADQ68885.1 E4NVK1  
 G3I44_09265   Halogeometricum borinquense wsp4 QIB74454.1    
 Hmuk_3174   Halomicrobium mukohataei DSM 12286 ACV49279.1 C7P2G4  
 GBQ70_03100 (NagZ)   Halomicrobium mukohataei ZPS1 QFR19486.1    
 LC1Hm_1210 (BglX)   Halomicrobium sp. LC1Hm QGA82267.1    
 LC1Hm_2617 (Bglx2)   Halomicrobium sp. LC1Hm QGA83650.1    
 LC1Hm_2524 (NagZ)   Halomicrobium sp. LC1Hm QGA83558.1    
 E5139_03100 (NagZ)   Halomicrobium sp. ZP60 QCD64679.1    
 Halxa_3779   Halopiger xanaduensis SH-6 AEH38385.1    
 Halxa_4062   Halopiger xanaduensis SH-6 AEH38667.1    
 Halxa_0372   Halopiger xanaduensis SH-6 AEH38975.1    
 Halxa_0375   Halopiger xanaduensis SH-6 AEH38978.1    
 Halxa_0663   Halopiger xanaduensis SH-6 AEH39240.1    
 Halxa_2401   Halopiger xanaduensis SH-6 AEH37020.1    
 Halxa_0358   Halopiger xanaduensis SH-6 AEH38961.1    
 Halxa_0665   Halopiger xanaduensis SH-6 AEH39242.1    
 FCF25_05110   Haloprofundus sp. MHR1 QCJ46530.1    
 Hrd1104_06775   Halorhabdus sp. CBA1104 QGN07027.1    
 Hrd1104_06085   Halorhabdus sp. CBA1104 QGN06906.1    
 Hrd1104_05760   Halorhabdus sp. CBA1104 QGN08198.1    
 HTIA_0724   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ32864.1    
 HTIA_1091   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33229.1    
 HTIA_1246   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33380.1    
 HTIA_1431   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33558.1    
 HTIA_2742   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ34845.1    
 HTIA_0904   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33043.1    
 Huta_1370   Halorhabdus utahensis DSM 12940 ACV11546.1 C7NNE6  
 Huta_2836   Halorhabdus utahensis DSM 12940 ACV12997.1 C7NQI0  
 Huta_1163   Halorhabdus utahensis DSM 12940 ACV11339.1 C7NMM6  
 Huta_1047   Halorhabdus utahensis DSM 12940 ACV11230.1 C7NVE6  
 Huta_0155   Halorhabdus utahensis DSM 12940 ACV10343.1 C7NP52  
 Huta_0867   Halorhabdus utahensis DSM 12940 ACV11050.1 C7NUF3  
 Huta_1607   Halorhabdus utahensis DSM 12940 ACV11781.1 C7NQ37  
 EO776_14550   Halorubrum ezzemoulense Fb21 QAY21131.1    
 DOS48_11575   Halorubrum sp. PV6 AZQ15935.1    
 I7X12_00395   Halosimplex litoreum YGH94 QPV63128.1    
 I7X12_15035   Halosimplex litoreum YGH94 QPV62052.1    
 I7X12_06620   Halosimplex litoreum YGH94 QPV64285.1    
 I7X12_19115 (fragment)   Halosimplex litoreum YGH94 QPV65160.1    
 HZS54_19385 (fragment)   Halosimplex pelagicum R2 QLH85055.1    
 HZS54_25055   Halosimplex pelagicum R2 QLH84710.1    
 HZS54_07195   Halosimplex pelagicum R2 QLH81423.1    
 HZS54_17355   Halosimplex pelagicum R2 QLH83290.1    
 HZS55_16585 (fragment)   Halosimplex rubrum R27 QLH80040.1    
 HZS55_21590   Halosimplex rubrum R27 QLH79724.1    
 HZS55_13380   Halosimplex rubrum R27 QLH78237.1    
 HZS55_06660   Halosimplex rubrum R27 QLH76994.1    
 HALLA_12845   Halostagnicola larsenii XH-48 AHF99545.1    
 HALLA_01775   Halostagnicola larsenii XH-48 AHG02057.1    
 HALLA_03250   Halostagnicola larsenii XH-48 AHG01417.1    
 HYG82_15735   Haloterrigena sp. YPL8 QLG51249.1    
 HYG82_03915   Haloterrigena sp. YPL8 QLG51135.1    
Top


Last update: 2021-01-11 © Copyright 1998-2021
AFMB - CNRS - Université d'Aix-Marseille