Glycoside Hydrolase Family 39

Activities in Familyα-L-iduronidase (EC 3.2.1.76); β-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); β-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (3687); Uniprot accession (270); PDB accession (30); 3D entries (11); cryst (0)
All (3623) Archaea (13) Bacteria (3432) Eukaryota (169) Viruses (1) unclassified (8) Structure (11) Characterized (23)
| 1 | 2 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N310_10907 (fragment)   Acanthisitta chloris KFP80781.1    
 AaeL_AAEL004402   Aedes aegypti Liverpool EAT44203.1    
 RP20_CCG013405   Aedes albopictus KXJ74538.1    
 Anapl_08696   Anas platyrhynchos EOB01746.1    
 ZHAS_00005970   Anopheles sinensis KFB38594.1    
 N321_01805 (fragment)   Antrostomus carolinensis KFZ62812.1    
 AS27_05681   Aptenodytes forsteri KFM04424.1    
 AN7117.2   Aspergillus nidulans FGSC A4 EAA61322.1 C8VDB5
Q5AX63
 
 IduA (short fragment)   Balaenoptera musculus AAX07735.1 Q5EC67  
 BCIN_09g04790   Botrytis cinerea B05.10 ATZ53683.1    
 glycoside hydrolase family 39 protein (Bofut4_p013400.1)   Botrytis cinerea T4 CCD43231.1    
 N320_10126 (fragment)   Buceros rhinoceros silvestris KFO90303.1    
 ORF (fragment)   Callorhinchus milii AFP02881.1    
 N300_02283   Calypte anna KFO99894.1    
 CB1_000328007   Camelus ferus EPY86101.1    
 α-L-iduronidase (IduA) 3.2.1.76 Canis lupus familiaris AAA51455.1 Q01634  
 CAPTEDRAFT_211572   Capitella teleta I ESC-2004 ELT95325.1    
 N322_04911 (fragment)   Cariama cristata KFP62135.1    
 N323_05242   Cathartes aura KFP51699.1    
 G4228_004486   Cervus hanglu yarkandensis KAF4013231.1    
 M959_03455   Chaetura pelagica KFU91764.1    
 EXN66_Car011783   Channa argus KAF3696107.1    
 N301_08744   Charadrius vociferus KGL91902.1    
 UY3_04246   Chelonia mydas EMP38551.1    
 N325_02401   Colius striatus KFP34469.1    
 D9C73_012014   Collichthys lucidus TKS79157.1    
 CSTEINMANNI_LOCUS890697 (fragment)   Coregonus sp. balchen CAB1319923.1    
 CSTEINMANNI_LOCUS1150772 (fragment)   Coregonus sp. balchen CAB1322122.1    
 N302_05728   Corvus brachyrhynchos KFO59804.1    
 I79_008932   Cricetulus griseus EGW07987.1    
 H671_7g18125   Cricetulus griseus 17A/GY ERE68177.1    
 H671_7g18125 (fragment)   Cricetulus griseus 17A/GY ERE68178.1    
 N303_06538   Cuculus canorus KFO78976.1    
 CpipJ_CPIJ014499   Culex quinquefasciatus JHB EDS40596.1    
 CH211-12E13.9-001   Danio rerio CAM46905.1
CAM13182.1
CAM13182.2
A2ARH2  
 Dana_GF14229   Drosophila ananassae TSC#14024-0371.13 EDV32059.1    
 Dbus_chr2Lg1829   Drosophila busckii ALC39744.1    
 Dere_GG10327   Drosophila erecta TSC#14021-0224.01 EDV58924.1    
 Dere_GG10327   Drosophila erecta TSC#14021-0224.01 KQS70575.1    
 Dgri_GH11437   Drosophila grimshawi TSC#15287-2541.00 EDW03800.1    
 CG6201   Drosophila melanogaster AAF53070.2
AAQ22532.1
NP_609489.1
Q9VKJ8  
 CG6201-RA, partial   Drosophila melanogaster y; cn bw sp AOQ05154.1    
 CG6201-RA   Drosophila melanogaster y; cn bw sp AOQ10961.1    
 Dmoj_GI14757   Drosophila mojavensis TSC#15081-1352.22 EDW11292.1    
 Dper_GL18590   Drosophila persimilis MSH-3 EDW29117.1    
 Dsec_GM11156   Drosophila sechellia Rob3c EDW52562.1    
 Dsim_GD22194   Drosophila simulans mixed EDX04665.1    
 Dsimw501_GD22194 (Dsim_gd22194)   Drosophila simulans w501 KMY89699.1    
 Dsimw501_GD22194 (Dsim_gd22194)   Drosophila simulans w501 KMY89700.1    
 Dvir_GJ17170   Drosophila virilis TSC#15010-1051.87 EDW63917.2    
 Dwil_GK18445   Drosophila willistoni TSC#14030-0811.24 EDW85284.1    
 Dyak_GE13010   Drosophila yakuba Tai18E2 EDW88046.1    
 Dyak_GE13010   Drosophila yakuba Tai18E2 KRJ97538.1    
 N307_13870   Dryobates pubescens KFV75478.1    
 Z169_13157   Egretta garzetta KFP16156.1    
 B566_EDAN007593 (fragment)   Ephemera danica KAF4526099.1    
 α-L-iduronidase (IduA;IDUA) 3.2.1.76 Felis catus AIT52923.1    
 H920_12825   Fukomys damarensis KFO25689.1    
 N327_07733   Fulmarus glacialis KFW07964.1    
 HYE67_001119   Fusarium culmorum Class2-1B QPC58888.1    
 CEK26_009398   Fusarium fujikuroi Augusto2 QGI96329.1    
 CEK26_010737   Fusarium fujikuroi Augusto2 QGI97668.1    
 CEK26_011651   Fusarium fujikuroi Augusto2 QGI98582.1    
 CEK26_009253 (fragment)   Fusarium fujikuroi Augusto2 QGI96184.1    
 CEK26_002695   Fusarium fujikuroi Augusto2 QGJ01251.1    
 CEK27_009273   Fusarium fujikuroi CSV1 QGI65302.1    
 CEK27_009419   Fusarium fujikuroi CSV1 QGI65448.1    
 CEK27_002691   Fusarium fujikuroi CSV1 QGI70362.1    
 CEK27_010753 (fragment)   Fusarium fujikuroi CSV1 QGI66782.1    
 CEK27_011668   Fusarium fujikuroi CSV1 QGI67697.1    
 CEK25_009280   Fusarium fujikuroi I1.3 QGI82551.1    
 CEK25_009429   Fusarium fujikuroi I1.3 QGI82700.1    
 CEK25_011658 (fragment)   Fusarium fujikuroi I1.3 QGI84929.1    
 CEK25_002676   Fusarium fujikuroi I1.3 QGI87720.1    
 CEK25_010748 (fragment)   Fusarium fujikuroi I1.3 QGI84019.1    
 FFUJ_05361   Fusarium fujikuroi IMI 58289 CCT69473.1    
 FFUJ_05526   Fusarium fujikuroi IMI 58289 CCT69625.1    
 FFUJ_08897   Fusarium fujikuroi IMI 58289 CCT71063.1    
 FFUJ_11044   Fusarium fujikuroi IMI 58289 CCT74970.1    
 FFUJ_13957   Fusarium fujikuroi IMI 58289 CCT72047.1    
 FGRAMCML3066_01t11499.1   Fusarium graminearum CZS80807.1    
 FGRAMCML3066_01t04287.1   Fusarium graminearum CZS77201.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF77514.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF73933.1    
 FOBC_09631   Fusarium oxysporum Fo47 QKD55516.1    
 FOBC_02743   Fusarium oxysporum Fo47 QKD48733.1    
 FOBC_09480   Fusarium oxysporum Fo47 QKD55367.1    
 FOBC_14529   Fusarium oxysporum Fo47 QKD60357.1    
 HYE68_001046   Fusarium pseudograminearum Class2-1C QPC70294.1    
 HYE68_006995   Fusarium pseudograminearum Class2-1C QPC76243.1    
 FVRRES_02095   Fusarium venenatum A3/5 CEI65583.1    
 FVRRES_05719   Fusarium venenatum A3/5 CEI61283.1    
 RCJMB04_31l23   Gallus gallus CAH65418.1 Q5F366  
 N328_12113   Gavia stellata KFV58592.1    
 N329_06163 (fragment)   Haliaeetus albicilla KFP97902.1    
 HERILL_LOCUS12027   Hermetia illucens CAD7089485.1    
 HERILL_LOCUS12027   Hermetia illucens CAD7089484.1    
 α-L-iduronidase (IduA) 3.2.1.76 Homo sapiens AAA81589.1
AAA51698.1
AAE53576.1
AAE72581.1
AAH29959.1
AAN25812.1
AAQ32908.1
AAQ46779.1
AAT18792.1
AAY01759.1
ABH73761.1
ABL21590.1
ACG93377.1
ACH14961.1
ACK10791.1
AFR32586.1
ASX95248.1
ASX95249.1
BAD92138.1
BAF84505.1
BAG54168.1
NP_000194.1
XP_042678.2
P35475 B[nd]
3W81[A,B]
3W82[A]
4JXO[A,B]
4JXP[A]
4KGJ[A,B]
4KGL[A,B]
4KH2[A,B]
4MJ2[A,B]
4MJ4[A]
4OBR[A,B]
4OBS[A]
6I6R[A,B]
6I6X[A,B]
 hCG_34451 (IduA) (fragment)   Homo sapiens EAW82616.1    
 hCG_34451 (IduA) (fragment)   Homo sapiens EAW82617.1    
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