Glycoside Hydrolase Family 38

Activities in Familyα-mannosidase (EC 3.2.1.24); mannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-1,6-mannosidase (EC 3.2.1.114); α-2-O-mannosylglycerate hydrolase (EC 3.2.1.170); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Statusmannosidase fold
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorNot known
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7301); Uniprot accession (536); PDB accession (76); 3D entries (9); cryst (2)
All (6902) Archaea (88) Bacteria (6179) Eukaryota (633) unclassified (2) Structure (9 - 2 cryst) Characterized (44)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 neutral α-mannosidase (Man2C1;6A8;6A8B) (cytosolic) 3.2.1.24 Homo sapiens AAC00190.2
AAC00568.1
AAH50550.1
AAH80191.1
ACM82923.1
AEE61026.1
BAD92378.1
BAG62758.1
CAB66810.1
CAH33915.1
CBA12854.1
CBA34894.1
NP_006706.1
Q13358
Q9NTJ4
 
 α-1,6-mannosidase (Man2B2;KIAA0935) 3.2.1.114 Homo sapiens CAD89971.1
AAH33307.1
AAH36836.1
AAH94773.1
ADO22337.1
BAA76779.1
BAA76779.2
BAG52093.1
BAH13490.1
CAF86562.1
NP_056089.1
XP_052620.6
Q9Y2E5
Q9Y2E5
 
 ORF (fragment)   Hypocrella siamensis MTCC 10142 ANH56472.1    
 AMAN, partial (fragment)   Hyptia floridana ASN78193.1    
 AMAN, partial (fragment)   Hyptia sp. 232 ASN78175.1    
 AMAN, partial (fragment)   Hyptia sp. 487 ASN78202.1    
 AMAN, partial (fragment)   Hyptia sp. 501 ASN78205.1    
 AMAN, partial (fragment)   Hyptia sp. 511 ASN78206.1    
 ORF (Man2b1)   Ictalurus punctatus AHH39379.1    
 KAFR_0B04640 (Kafr0b04640)   Kazachstania africana CBS 2517 CCF56761.1    
 KNAG_0I00600 (Knag0i00600)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK71851.1    
 ATY40_BA7504519 (Ams1)   Komagataella pastoris ATCC 28485 ANZ77973.1    
 AT249_GQ6705181 (Ams1)   Komagataella phaffii ATCC 76273 AOA65028.1    
 PP7435_Chr4-0161 (Ams1)   Komagataella phaffii CBS 7435 CCA40336.1
SOP83089.1
   
 PAS_chr4_0790   Komagataella phaffii GS115 CAY72059.1
AOA69506.1
C4R8Y4  
 KLTH0G11000g   Lachancea thermotolerans CBS 6340 CAR25074.1    
 LSAL_LOCUS8289 (fragment)   Lactuca saligna CAB4079737.1    
 LSAL_LOCUS16422   Lactuca saligna CAB4088353.1    
 LSAL_LOCUS9073 (fragment)   Lactuca saligna CAB4080569.1    
 LSAL_LOCUS20387   Lactuca saligna CAB4092557.1    
 LSAL_LOCUS19177 (fragment)   Lactuca saligna CAB4091278.1    
 LSAL_LOCUS22820 (fragment)   Lactuca saligna CAB4095121.1    
 LSAL_LOCUS23017   Lactuca saligna CAB4095324.1    
 LSAL_LOCUS33064 (fragment)   Lactuca saligna CAB4105978.1    
 LSAL_LOCUS38830 (fragment)   Lactuca saligna CAB4112080.1    
 LSAL_LOCUS890 (fragment)   Lactuca saligna CAB4071945.1    
 LSAL_LOCUS3670   Lactuca saligna CAB4074864.1    
 LSINAPIS_LOCUS12461 (fragment)   Leptidea sinapis VUZ02239.1    
 LSINAPIS_LOCUS5147 (fragment)   Leptidea sinapis VUY92825.1    
 LSINAPIS_LOCUS6680 (fragment)   Leptidea sinapis VUY94855.1    
 LSINAPIS_LOCUS5147 (fragment)   Leptidea sinapis VUY92826.1    
 LSINAPIS_LOCUS2328   Leptidea sinapis VUY89115.1    
 LSINAPIS_LOCUS2397 (fragment)   Leptidea sinapis VUY89221.1    
 LSINAPIS_LOCUS12024 (fragment)   Leptidea sinapis VUZ01699.1    
 LSINAPIS_LOCUS6680 (fragment)   Leptidea sinapis VUY94854.1    
 LSINAPIS_LOCUS12022   Leptidea sinapis VUZ01697.1    
 LSINAPIS_LOCUS2398 (fragment)   Leptidea sinapis VUY89222.1    
 LSINAPIS_LOCUS5148 (fragment)   Leptidea sinapis VUY92827.1    
 ORF   Leptosphaeria maculans JN3 CBX95677.1 E4ZVQ1  
 LRAMOSA06239   Lichtheimia ramosa CDS14068.1    
 LRAMOSA08895   Lichtheimia ramosa CDS06367.1    
 ORF (fragment)   Linum usitatissimum ADD54604.1 D4P875  
 α-mannosidase (MAN2B1)   Macaca fascicularis BAD51966.1 Q60HE9  
 unnamed protein product (fragment)   Macaca fascicularis BAE88765.1    
 epididymis-specific α-mannosidase precursor (Man2b2)   Macaca mulatta AFE67111.1    
 α-mannosidase 2 (Man2a1)   Macaca mulatta AFE66336.1
AFH29699.1
AFI34553.1
   
 α-mannosidase 2x (Man2a2)   Macaca mulatta AFE78271.1    
 α-mannosidase 2C1, partial (Man2c1) (fragment)   Macaca mulatta AFE70405.1
AFI33686.1
   
 lysosomal α-mannosidase isoform 1 precursor (Man2b1)   Macaca mulatta AFI37135.1    
 lysosomal α-mannosidase isoform 1 precursor (Man2b1)   Macaca mulatta AFJ71498.1    
 α-D-mannosidase isoform 2, partial (fragment)   Mangifera indica AJZ77342.1    
 α-D-mannosidase isoform 3, partial (fragment)   Mangifera indica AJZ77343.1    
 α-D-mannosidase isoform 1, partial (fragment)   Mangifera indica AJZ77341.1    
 Mp_6g08660   Marchantia polymorpha subsp. ruderalis Tak-1 BBN14077.1    
 Mp_4g13950   Marchantia polymorpha subsp. ruderalis Tak-1 BBN08729.1    
 Mp_6g09110   Marchantia polymorpha subsp. ruderalis Tak-1 BBN14131.1    
 MTYFT1G-G-13 (fragment)   Medicago truncatula ACJ86251.1 B7FNB8  
 MtrDRAFT_AC141109g20v1   Medicago truncatula ABE79912.1
ABO80520.1
ABO80521.1
   
 α-1,2-mannosidase (LMann;MtLMann;MtrDRAFT_AC148217g19v1) 3.2.1.113 Medicago truncatula ABE88173.1
AIX48011.1
XP_003629280.1
G7LB83  
 BN887_02677   Melanopsichium pennsylvanicum 4 CDI51481.1    
 G6M90_00g012290 (Ams1)   Metarhizium brunneum 4556 QLI64758.1    
 METSCH_A09640 (Mpul0a09640)   Metschnikowia aff. pulcherrima APC 1.2 QBM86327.1    
 AMAN, partial (fragment)   Micrevania sp. 288 ASN78191.1    
 MICPUN_62552   Micromonas commoda sp. RCC299 ACO66199.1 C1EEA2  
 MICPUN_62591   Micromonas commoda sp. RCC299 ACO66520.1 C1EEE2  
 GNLVRS01_PISO0H05089g (Piso0_003109)   Millerozyma farinosa CBS 7064 CCE80778.1    
 GNLVRS01_PISO0G05088g (Piso0_003109)   Millerozyma farinosa CBS 7064 CCE80013.1    
 α-mannosidase (Man2c1;C330035A14;1110025H24) (cytosolic) 3.2.1.24 Mus musculus AAH16253.1
AAH39913.1
AAY53557.1
BAB23074.1
BAC33715.1
BAE32264.1
BAE42254.1
BAE42554.1
NP_082912.1
Q3ZCX9
Q80XU4
Q8BWY6
Q91W89
Q9CTD5
 
 α-mannosidase (Man2B2;Kiaa0935) 3.2.1.24 Mus musculus BAA24266.1
AAH66211.1
BAB23655.1
BAC30580.1
BAC53862.1
BAD32345.1
BAE30761.1
BAE31143.1
BAE38153.1
NP_032576.1
O54782  
 α-mannosidase (Man2b;LMann;MmLMann) (lysosomal) 3.2.1.24 Mus musculus NP_034894.2
AAC09470.1
AAC53369.1
AAC78560.1
AAH05430.1
AIX48012.1
BAB23588.1
BAE28235.1
BAE42071.1
BAE42288.1
BAE42419.1
NP_034894.1
O09159
Q3UGH3
 
 α-mannosidase II (Man2A1;ManA2) 3.2.1.114 Mus musculus CAA43480.1
AAI38373.1
BAC38329.1
CAH33910.1
CBA12849.1
CBA34889.1
NP_032575.1
P27046
Q8C4L1
 
 α-mannosidase IIx (Man2A2) 3.2.1.114 Mus musculus ABG02551.1
AAD20813.1
AAH55006.1
BAC31745.1
BAE36580.1
NP_766491.1
Q197W7
Q7TPQ0
Q8BRK9
Q9WU23
 
 ORF   Mus musculus C57BL/6J AQS27599.1    
 unnamed protein product (fragment)   Mus musculus C57BL/6J BAE23268.1 Q197W7
Q3UVK1
Q8BRK9
 
 ORF   Musca domestica ALHF AFP62178.1    
 ORF (fragment)   Musca domestica ALHF AFP62267.1    
 ORF (fragment)   Mustela putorius furo AES01501.1    
 ORF (fragment)   Mustela putorius furo AES01502.1    
 ORF (fragment)   Mustela putorius furo AES01503.1    
 ORF (fragment)   Mustela putorius furo AES01504.1    
 ORF (fragment)   Mustela putorius furo AES01506.1    
 ORF (fragment)   Mustela putorius furo AES01511.1    
 ORF (fragment)   Mustela putorius furo AES01512.1    
 ORF (fragment)   Mustela putorius furo AES01500.1    
 ORF (fragment)   Mustela putorius furo AES01505.1    
 ORF (fragment)   Mustela putorius furo AES01508.1    
 ORF (fragment)   Mustela putorius furo AES01509.1    
 NGATSA_3021300 (fragment)   Nannochloropsis gaditana CCMP526 AFJ68737.1    
 NGATSA_3022100 (fragment)   Nannochloropsis gaditana CCMP526 AFJ68858.1    
 NCAS_0D00720 (Ncas0d00720)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC69653.1    
 NDAI_0H03450 (Ndai0h03450)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD26518.1    
 ORF (fragment)   Neslia paniculata ADG39054.1 D6PRS2  
 NCU07404.1   Neurospora crassa OR74A EAA29252.1
XP_327690.1
Q7S1L0  
 ORF   Nilaparvata lugens ANJ04662.1    
 seminal fluid protein   Nilaparvata lugens APA33853.1    
 NMOB1V02_LOCUS4696 (fragment)   Notodromas monacha CAD7276953.1    
 NMOB1V02_LOCUS5732   Notodromas monacha CAD7278017.1    
 NMOB1V02_LOCUS5917 (fragment)   Notodromas monacha CAD7278206.1    
 NMOB1V02_LOCUS6672 (fragment)   Notodromas monacha CAD7278984.1    
 NMOB1V02_LOCUS6672 (fragment)   Notodromas monacha CAD7278983.1    
Top


Last update: 2021-01-11 © Copyright 1998-2021
AFMB - CNRS - Université d'Aix-Marseille