Glycoside Hydrolase Family 36

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); stachyose synthase (EC 2.4.1.67); raffinose synthase (EC 2.4.1.82)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
NoteMechanistic commonality with family GH27 demonstrated by Comfort et al. (2007) Biochemistry, 46: 3319-3330 (PMID: 17323919)
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3496); Uniprot accession (584); PDB accession (17); 3D entries (6); cryst (0)
All (3274) Archaea (31) Bacteria (3057) Eukaryota (185) unclassified (1) Structure (6) Characterized (66)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Ahos_0347   Acidianus hospitalis W1 AEE93238.1    
 B6F84_04940   Acidianus manzaensis YN-25 ARM75438.1    
 ASAC_0639   Acidilobus saccharovorans 345-15 ADL19045.1 D9Q157  
 Cmaq_1025   Caldivirga maquilingensis IC-167 ABW01856.1 A8MDK0  
 CPM_0103   Cuniculiplasma divulgatum PM4 (=JCM 30641; =VKM B-2940) SJK83998.1    
 CSP5_0133   Cuniculiplasma divulgatum S5(T) (=JCM 30642; =VKM B-2941) SIM32630.1    
 DKAM_0710   Desulfurococcus amylolyticus 1221n ACL11036.1 B8D4K5  
 Desfe_0800   Desulfurococcus amylolyticus DSM 16532 AFL66691.1    
 Hlac_2869   Halorubrum lacusprofundi ATCC 49239 ACM58429.1 B9LW39  
 Igag_0311   Ignisphaera aggregans DSM 17230 ADM27157.1 E0SQT3  
 SiH_2182   Sulfolobus islandicus HVE10/4 ADX83523.1    
 LD85_2513   Sulfolobus islandicus L.D.8.5 ADB88150.1 D2PFN4  
 LS215_2406   Sulfolobus islandicus L.S.2.15 ACP36380.1 C3MKK9  
 SiL_2087   Sulfolobus islandicus LAL14/1 AGJ63530.1    
 M1425_2239   Sulfolobus islandicus M.14.25 ACP38972.1 C3MS29  
 M1627_2318   Sulfolobus islandicus M.16.27 ACP56177.1 C3N1F0  
 M164_2240   Sulfolobus islandicus M.16.4 ACR42842.1 C4KKI0  
 SiRe_2123   Sulfolobus islandicus REY15A ADX86179.1    
 YG5714_2372   Sulfolobus islandicus Y.G.57.14 ACP46618.1 C3N9P6  
 YN1551_0536   Sulfolobus islandicus Y.N.15.51 ACP47682.1 C3NLT4  
 Ssol_0866   Sulfolobus solfataricus 98/2 ACX91112.1 D0KQU3  
 SULC_0903   Sulfolobus solfataricus 98/2 SULC AKA75954.1    
 SSOP1_3215   Sulfolobus solfataricus P1 SAI86769.1    
 α-galactosidase (SSO3127) 3.2.1.22 Sulfolobus solfataricus P2 AAK43227.1
CAC24100.1
NP_344437.1
Q97U94  
 SULA_0902   Sulfolobus solfataricus SULA AKA78647.1    
 SULB_0904   Sulfolobus solfataricus SULB AKA73255.1    
 BFU36_06315   Sulfolobus sp. A20 AOL16378.1    
 α-galactosidase (ST2554) 3.2.1.22 Sulfolobus tokodaii str. 7 BAB67666.1
BAK54821.1
NP_378557.1
Q96XG2  
 TUZN_1456   Thermoproteus uzoniensis 768-20 AEA12928.1    
 Vdis_0070   Vulcanisaeta distributa DSM 14429 ADN49485.1 E1QS92  
 VMUT_0953   Vulcanisaeta moutnovskia 768-28 ADY01163.1    
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