Glycoside Hydrolase Family 35

Activities in Familyβ-galactosidase (EC 3.2.1.23); exo-β-glucosaminidase (EC 3.2.1.165); exo-β-1,4-galactanase (EC 3.2.1.-); β-1,3-galactosidase (EC 3.2.1.-)
Mechanism Retaining (inferred)
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2771); Uniprot accession (531); PDB accession (27); 3D entries (12); cryst (0)
All (1923) Archaea (22) Bacteria (1438) Eukaryota (459) unclassified (4) Structure (12) Characterized (72)
| 1 | 2 | 3 | 4 | 5 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-galactosidase 3   Camellia sinensis AHC32021.1    
 Bgal2   Camellia sinensis AHG94611.1    
 Bgal3   Camellia sinensis AHG94612.1    
 Bgal4   Camellia sinensis AHG94613.1    
 β-galactosidase (Glb1) 3.2.1.23 Canis lupus familiaris AAE53102.1
AAB50770.1
AAC12775.1
AAT65211.1
AAU05604.1
AAU05608.1
AAU05610.1
AAV32505.1
ABA43388.1
Q9TRY9  
 β-galactosidase (Pbg1;Bg1) 3.2.1.23 Capsicum annuum AAK40304.1
BAC10578.2
CAW89031.1
CAW89047.1
CAW93291.1
CAW93305.1
CAW98532.1
CAW98546.1
CAX05350.1
CAX05363.1
CBD12123.1
CBD12135.1
Q8LP12
Q93XM4
 
 β-galactosidase 3.2.1.23 Carica papaya AAC77377.1
ABH99893.1
ABI12870.1
ACC78255.1
CAD44519.1
CAW88925.1
CAW93193.1
CAW98423.1
CAX05300.1
CBD12037.1
Q9ZP30  
 β-galactosidase (fragment)   Carica papaya CAA10064.1 Q9ZRW7  
 β-galactosidase (fragment)   Carica papaya AAC28739.1 O81611  
 β-galactosidase pBG(b)   Carica papaya ACP18874.1 C3VDH8  
 β-galactosidase pBG(a)   Carica papaya ACP18875.1 C3VDH9  
 β-galactosidase (fragment)   Carica papaya AAY18074.1 Q52H50  
 β-galactosidase (fragment)   Carica papaya AAY18075.1 Q52H49  
 β-galactosidase (CpGAL;CanBGal-5) 3.2.1.23 Cicer arietinum CAA10128.1 Q9ZRV9  
 β-galactosidase (?III-Gal;CanBGal-3) 3.2.1.23 Cicer arietinum CAA06309.1 O65736  
 β-galactosidase (CanBGal-4) 3.2.1.23 Cicer arietinum CAA09457.1 O82670  
 β-galactosidase (CanBGal-2) (fragment)   Cicer arietinum CAA06310.1 O65737  
 β-galactosidase (BgaL;?I-Gal;CanBGal-1)   Cicer arietinum CAA07236.2
CAA07236.1
O65761  
 β-galactosidase 3.2.1.23 Citrus sinensis AAK31801.1
CAW89029.1
CAW93289.1
CAW98530.1
CAX05348.1
CBD12121.1
Q8L5Q9  
 β-galactosidase (BgaL) 3.2.1.23 Coffea arabica ADX59436.1    
 CYME_CMP078C   Cyanidioschyzon merolae strain 10D BAM81731.1    
 Unknown (protein for MGC:110823)   Danio rerio AAH92166.1
AAI65636.1
CAM14065.1
Q56A50  
 DKEY-224E22.2-001   Danio rerio CAM13012.1
CAM13013.1
A2BIK1  
 MGC:175208 IMAGE:8999016 (Glb1L)   Danio rerio AAI66043.1 B2GTW9  
 ORF (fragment)   Dendrobium hybrid cultivar AIZ46896.1    
 unknown   Dendroctonus ponderosae AEE62912.1    
 unknown   Dendroctonus ponderosae AEE63027.1    
 unknown   Dendroctonus ponderosae AEE63211.1    
 β-galactosidase (SR12) 3.2.1.23 Dianthus caryophyllus AAE35914.1
CAA40459.1
Q00662  
 β-galactosidase (Gal3)   Diospyros kaki AJQ19480.1    
 β-galactosidase (Gal1)   Diospyros kaki AJQ19478.1    
 β-galactosidase, partial (Gal4) (fragment)   Diospyros kaki AJQ19481.1
AOR05807.1
   
 β-galactosidase (Gal2)   Diospyros kaki AJQ19479.1
AOR05813.1
   
 β-galactosidase 3, partial (fragment)   Diospyros kaki AOR05808.1    
 β-galactosidase 6, partial (fragment)   Diospyros kaki AOR05811.1    
 β-galactosidase 4, partial   Diospyros kaki AOR05809.1    
 β-galactosidase 1, partial   Diospyros kaki AOR05806.1    
 β-galactosidase (fragment)   Diospyros kaki AEM72517.1    
 β-galactosidase (fragment)   Diospyros kaki AEM72518.1    
 ORF (fragment)   Dissotrocha aculeata ALG76120.1    
 Dbus_chr2Lg854   Drosophila busckii ALC38769.1    
 Dbus_chr3Rg663   Drosophila busckii ALC45913.1    
 CG3132   Drosophila melanogaster AAF54736.1
AAM50219.1
NP_650142.1
Q9VGE7  
 CG9092   Drosophila melanogaster AAM50936.1
AAF52321.2
AGB92656.1
NP_608978.2
Q9VMJ5  
 β-galactosidase (Glb1) (fragment)   Eira barbara ABV57142.1 B3FG75  
 β-galactosidase (Glb1) (fragment)   Enhydra lutris ABV57112.1 B3FG45  
 β-galactosidase (fragment)   Eurygaster integriceps AFM52338.1    
 unnamed protein product   Eutrema halophilum BAJ34544.1 E4MY61  
 β-galactosidase (Glb1;Bgal ) 3.2.1.23 Felis catus AAB81350.1
AAB86405.1
O19015  
 β-galactosidase 2 (fragment)   Ficus carica AAR27062.1 Q6RX16  
 β-galactosidase 1 (fragment)   Ficus carica AAR27061.1 Q6RX17  
 ORF   Flammulina velutipes KACC 42777 ADX07308.1    
 β-Gal1 (fragment)   Fragaria chiloensis ADW19770.1    
 β-galactosidase 4 (Fa?Gal4)   Fragaria x ananassa ALH22329.1    
 β-galactosidase 3 (Fa?Gal3) 3.2.1.23 Fragaria x ananassa CAC44502.1
CAW89039.1
CAW93298.1
CAW98540.1
CAX05357.1
CBD12129.1
Q93X56  
 β-galactosidase 2 (Fa?Gal2) 3.2.1.23 Fragaria x ananassa CAC44501.1
CAW89042.1
CAW93300.1
CAW98542.1
CAX05359.1
CBD12131.1
Q93X57  
 β-galactosidase 1 (Fa?Gal1) 3.2.1.23 Fragaria x ananassa CAC44500.1
CAW89045.1
CAW93302.1
CAW98544.1
CAX05361.1
CBD12133.1
Q93X58  
 FFUJ_09341   Fusarium fujikuroi IMI 58289 CCT73835.1    
 FFUJ_10776   Fusarium fujikuroi IMI 58289 CCT74713.1    
 FGRAMPH1_01T12655   Fusarium graminearum PH-1 SCB65799.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86341.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78802.1    
 β-galactosidase (Glb1) (fragment)   Galictis cuja ABV57145.1 B3FG78  
 β-galactosidase (Glb1) (fragment)   Galictis vittata ABV57144.1 B3FG77  
 RCJMB04_5i4 (fragment)   Gallus gallus CAG31369.1 Q5ZLM4  
 β-galactosidase   Glossina morsitans morsitans ADD18655.1 D3TLS7  
 unnamed protein product   Glycine max CAW94407.1
CAX00843.1
CBD03819.1
   
 unnamed protein product   Glycine max CAW89092.1
CAW93347.1
CAX05401.1
CBD12171.1
   
 β-galactosidase   Glycine max ACF22882.1 C6F122  
 unknown   Glycine max ACU17905.1 C6T7V3  
 unnamed protein product   Glycine max CBD34629.1    
 ORF   Glycine max AAQ62586.1
CAW89023.1
CAW93284.1
CAW98525.1
CAX05344.1
CBD12117.1
Q6X0N7  
 ORF   Glycine max CAM55725.1
CAW94414.1
CAX00851.1
CBD03826.1
CBD34628.1
CBD34630.1
CBD34631.1
   
 ORF   Glycine max CAM55756.1    
 ORF   Glycine max CAM55758.1    
 β-galactosidase (Gal1)   Gossypium hirsutum AAS76480.1
CAC84109.1
A4D0F8
Q8W4Z8
 
 β-galactosidase (Glb1) (fragment)   Gulo gulo ABV57141.1 B3FG74  
 unnamed protein product (fragment)   Homo sapiens BAC11155.1
CAF85896.1
NP_775852.1
Q8NCI6  
 β-galactosidase (Glb1) 3.2.1.23 Homo sapiens AAA51819.1
AAA35599.1
AAA51822.1
AAA51823.1
AAH07493.1
AAP35811.1
ACM84364.1
BAD96483.1
BAD96811.1
BAH12915.1
BAH13196.1
BAH13341.1
CBA12839.1
NP_000395.1
P16278
P16279
3THC[A,B,C,D]
3THD[A,B,C,D]
3WEZ[A,B,C,D]
3WF0[A,B,C,D]
3WF1[A,B,C,D]
3WF2[A,B,C,D]
3WF3[A,B,C,D]
3WF4[A,B,C,D]
 MGC10771   Homo sapiens CAC51167.1
AAH03523.1
AAQ89002.1
AAR67753.1
AAS23602.1
AAS33128.1
AAU96022.1
AAV25910.1
AAW11555.1
AAW13884.1
AAW14383.1
AAW18911.1
AAX07034.1
AAY11611.1
AAY73791.1
ABA68603.1
ABC13935.1
ABC14000.1
ABE12074.1
ABE14316.1
ABH71495.1
ABH98702.1
ABI01120.1
ABI12092.1
ABJ28884.1
ABL21712.1
ABX93830.1
ABX96123.1
ABX96433.1
ABX96743.1
ABY04897.1
ABY16608.1
ABY18633.1
ACC30826.1
ACC32338.1
ACC33265.1
ACC36048.1
ACC36383.1
ACE08624.1
ACG89535.1
ACJ99830.1
ACM94941.1
ACP73696.1
ACS06322.1
ACW19782.1
AEE60987.1
BAB70855.1
BAG61387.1
BAG61983.1
NP_078782.3
Q6UWU2
Q96DR0
 
 LOC89944 / BC008326 (Glb1l2)   Homo sapiens BAC11247.1
AAH08326.1
AAH40641.1
AAQ13636.1
AAQ88861.1
AAR67752.1
AAS23601.1
AAS33127.1
AAU96021.1
AAV25909.1
AAW11554.1
AAW13883.1
AAW14382.1
AAW18910.1
AAX07033.1
AAY11610.1
AAY73790.1
ABA68602.1
ABC13934.1
ABC13999.1
ABE12073.1
ABH71494.1
ABH98701.1
ABI01119.1
ABI12090.1
ABJ28883.1
ABL21710.1
ABX93828.1
ABX96121.1
ABX96431.1
ABX96741.1
ABY04895.1
ABY16607.1
ABY18631.1
ACC07446.1
ACC17164.1
ACC22976.1
ACC23545.1
ACE08622.1
ACE15069.1
ACG89533.1
ACJ99828.1
ACM94939.1
ACP73694.1
ACS06320.1
ACW19781.1
BAC11149.1
BAC11179.1
BAC11309.1
CAF86041.1
CAF86144.1
CAF86793.1
CAF86946.1
NP_612351.2
Q8IW92
Q8NCG3
 
 IMAGE 3938286 (fragment)   Homo sapiens AAH11001.1
AAH11001.2
NP_612425.1
XP_053517.1
Q8NCI6  
 B-GAL1   Hordeum vulgare CAG30724.1
CAW94435.1
CAX00873.1
CBD03844.1
Q5LJJ2  
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAJ89450.1    
 β-galactosidase (Glb1) (fragment)   Hydrictis maculicollis ABV57117.1 B3FG50  
 β-galactosidase (BgaL)   Hylocereus undatus AHL69742.1    
 Bgal1 (fragment)   Hymenaea courbaril var. stilbocarpa ABY82047.1 B0LSQ9  
 ORF   Hypocrella siamensis MTCC 10142 ANH56446.1    
 β-galactosidase (Glb1) (fragment)   Ictonyx libyca ABV57122.1 B3FG55  
 β-galactosidase (Glb1) (fragment)   Ictonyx striatus ABV57143.1 B3FG76  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX90771.1 E4ZIB0  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92575.1 E4ZMX2  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX93453.1 E4ZPR8  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97989.1 E5A3W5  
 LRAMOSA10529   Lichtheimia ramosa CDS09169.1    
 LRAMOSA00048   Lichtheimia ramosa CDS02643.1    
 β-galactosidase (Bgal1) 3.2.1.23 Linum usitatissimum AEG76892.1
AEG76893.1
   
 β-galactosidase (Glb1) (fragment)   Lontra canadensis ABV57113.1 B3FG46  
 β-galactosidase (Glb1) (fragment)   Lontra felina ABV57114.1 B3FG47  
 β-galactosidase (Glb1) (fragment)   Lontra longicaudis ABV57115.1 B3FG48  
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