Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5098); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4861) Archaea (1) Bacteria (4415) Eukaryota (389) Viruses (34) unclassified (22) Structure (19) Characterized (96)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GH33, Sialidase   uncultured organism VDS02533.1    
 GH33, Sialidase   uncultured organism VDS02708.1    
 GH33, Sialidase   uncultured organism VDS02649.1    
 GH33, Sialidase   uncultured organism VDS02612.1    
 GH33, Sialidase   uncultured organism VDS02618.1    
 GH33, Sialidase   uncultured organism VDS02578.1    
 EYD13_14690 (Neda1)   Saccharomonospora sp. 31sw QBQ61286.1    
 EYD13_19425 (Neda2)   Saccharomonospora sp. 31sw QBQ62224.1    
 EYD13_19430 (Neda3)   Saccharomonospora sp. 31sw QBQ62225.1    
 E3D81_00315   Sphingobacterium sp. CZ-2 QBR10704.1    
 E3D81_00320   Sphingobacterium sp. CZ-2 QBR10705.1    
 E3D81_09360   Sphingobacterium sp. CZ-2 QBR12354.1    
 E3D81_00305   Sphingobacterium sp. CZ-2 QBR10702.1    
 E3Z29_19150   Pseudomonas sp. S150 QBR32490.1    
 E5N77_30665   Streptomyces sp. SS52 QCB25691.1    
 E5206_02800   Arthrobacter sp. PAMC25564 QCB95995.1    
 E7747_00390   Muribaculum sp. H5 QCD40903.1    
 E7745_02940 (fragment)   Duncaniella sp. C9 QCD38586.1    
 FCN77_06040   Arthrobacter sp. 24S4-2 QCO97358.1    
 FCN45_01955   unidentified QCP58221.1    
 EHF32_13165   unidentified QCQ18241.1    
 FDZ78_06670 (fragment)   unidentified QCP72278.1    
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