Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | ... | 58 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMEA2434623_01540 (NanB)   Streptococcus pneumoniae 2245STDY5775666 VFH89459.1    
 SAMEA2434829_01541 (Nanb_2)   Streptococcus pneumoniae 2245STDY5775874 VFH79547.1    
 SAMEA2434829_01541 (Nanb_2)   Streptococcus pneumoniae 2245STDY5775874 VFH79547.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5775874 VFH79602.1    
 SAMEA2434829_01217 (Nanb_1)   Streptococcus pneumoniae 2245STDY5775874 VFH77471.1    
 SAMEA2434829_01217 (Nanb_1)   Streptococcus pneumoniae 2245STDY5775874 VFH77471.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5868782 VFH87717.1    
 SAMEA2627289_01592 (Nanb_2)   Streptococcus pneumoniae 2245STDY5868782 VFH87674.1    
 SAMEA2627289_01592 (Nanb_2)   Streptococcus pneumoniae 2245STDY5868782 VFH87674.1    
 SAMEA2627289_01227 (Nanb_1)   Streptococcus pneumoniae 2245STDY5868782 VFH85106.1    
 SAMEA2627289_01227 (Nanb_1)   Streptococcus pneumoniae 2245STDY5868782 VFH85106.1    
 SAMEA2796698_01467 (NanB)   Streptococcus pneumoniae 2245STDY5982722 VFH80907.1    
 SAMEA2796698_01467 (NanB)   Streptococcus pneumoniae 2245STDY5982722 VFH80907.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5982722 VFH80961.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5983173 VFH88568.1    
 SAMEA2797120_01586 (NanB)   Streptococcus pneumoniae 2245STDY5983173 VFH88527.1    
 SAMEA2797120_01586 (NanB)   Streptococcus pneumoniae 2245STDY5983173 VFH88527.1    
 SAMEA3175698_01589 (NanB)   Streptococcus pneumoniae 2245STDY6020210 VFI05302.1    
 SAMEA3175698_01589 (NanB)   Streptococcus pneumoniae 2245STDY6020210 VFI05302.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6020210 VFI05353.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6020221 VFI10083.1    
 SAMEA3175709_01562 (NanB)   Streptococcus pneumoniae 2245STDY6020221 VFI10055.1    
 SAMEA3175709_01562 (NanB)   Streptococcus pneumoniae 2245STDY6020221 VFI10055.1    
 SAMEA3175728_01542 (NanB)   Streptococcus pneumoniae 2245STDY6020240 VGM75529.1    
 SAMEA3175728_01542 (NanB)   Streptococcus pneumoniae 2245STDY6020240 VGM75529.1    
 SAMEA3175728_01548 (Nana_2)   Streptococcus pneumoniae 2245STDY6020240 VGM75541.1    
 SAMEA3233211_01639 (NanB)   Streptococcus pneumoniae 2245STDY6030848 VFH95434.1    
 SAMEA3233211_01639 (NanB)   Streptococcus pneumoniae 2245STDY6030848 VFH95434.1    
 neuraminidase (Nana_4)   Streptococcus pneumoniae 2245STDY6030848 VFH95451.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6031034 VFI10264.1    
 SAMEA3233395_01583 (Nanb_2)   Streptococcus pneumoniae 2245STDY6031034 VFI10236.1    
 SAMEA3233395_01583 (Nanb_2)   Streptococcus pneumoniae 2245STDY6031034 VFI10236.1    
 SAMEA3233395_01277 (Nanb_1)   Streptococcus pneumoniae 2245STDY6031034 VFI08328.1    
 SAMEA3233395_01277 (Nanb_1)   Streptococcus pneumoniae 2245STDY6031034 VFI08328.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6031048 VFI04459.1    
 SAMEA3233409_01589 (NanB)   Streptococcus pneumoniae 2245STDY6031048 VFI04413.1    
 SAMEA3233409_01589 (NanB)   Streptococcus pneumoniae 2245STDY6031048 VFI04413.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6092581 VFI07373.1    
 SAMEA3354333_01626 (NanB)   Streptococcus pneumoniae 2245STDY6092581 VFI07325.1    
 SAMEA3354333_01626 (NanB)   Streptococcus pneumoniae 2245STDY6092581 VFI07325.1    
 SAMEA3354357_01664 (NanB)   Streptococcus pneumoniae 2245STDY6092613 VFI09961.1    
 SAMEA3354357_01664 (NanB)   Streptococcus pneumoniae 2245STDY6092613 VFI09961.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6092613 VFI09988.1    
 SAMEA3381325_01569 (NanB)   Streptococcus pneumoniae 2245STDY6092834 VFI09582.1    
 SAMEA3381325_01569 (NanB)   Streptococcus pneumoniae 2245STDY6092834 VFI09582.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6092834 VFI09620.1    
 SAMEA3381439_01658 (Nanb_2)   Streptococcus pneumoniae 2245STDY6092949 VFI28817.1    
 SAMEA3381439_01658 (Nanb_2)   Streptococcus pneumoniae 2245STDY6092949 VFI28817.1    
 SAMEA3381439_01266 (Nanb_1)   Streptococcus pneumoniae 2245STDY6092949 VFI26901.1    
 SAMEA3381439_01266 (Nanb_1)   Streptococcus pneumoniae 2245STDY6092949 VFI26901.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6092949 VFI28847.1    
 SAMEA3381491_01596 (Nanb_2)   Streptococcus pneumoniae 2245STDY6093044 VFI13832.1    
 SAMEA3381491_01596 (Nanb_2)   Streptococcus pneumoniae 2245STDY6093044 VFI13832.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6093044 VFI13838.1    
 SAMEA3381491_01293 (Nanb_1)   Streptococcus pneumoniae 2245STDY6093044 VFI13537.1    
 SAMEA3381491_01293 (Nanb_1)   Streptococcus pneumoniae 2245STDY6093044 VFI13537.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6105839 VFI45434.1    
 SAMEA3389228_01536 (NanB)   Streptococcus pneumoniae 2245STDY6105839 VFI45400.1    
 SAMEA3389228_01536 (NanB)   Streptococcus pneumoniae 2245STDY6105839 VFI45400.1    
 SAMEA3389261_01464 (Nana_2)   Streptococcus pneumoniae 2245STDY6105855 VGM83091.1    
 SAMEA3389261_01458 (NanB)   Streptococcus pneumoniae 2245STDY6105855 VGM83073.1    
 SAMEA3389261_01458 (NanB)   Streptococcus pneumoniae 2245STDY6105855 VGM83073.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6106337 VFI19835.1    
 SAMEA3390054_01590 (NanB)   Streptococcus pneumoniae 2245STDY6106337 VFI19788.1    
 SAMEA3390054_01590 (NanB)   Streptococcus pneumoniae 2245STDY6106337 VFI19788.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106372 VFI27705.1    
 SAMEA3389940_01191 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106372 VFI25948.1    
 SAMEA3389940_01191 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106372 VFI25948.1    
 SAMEA3389940_01504 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106372 VFI27678.1    
 SAMEA3389940_01504 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106372 VFI27678.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106384 VFI28196.1    
 SAMEA3389963_01562 (NanB)   Streptococcus pneumoniae 2245STDY6106384 VFI28166.1    
 SAMEA3389963_01562 (NanB)   Streptococcus pneumoniae 2245STDY6106384 VFI28166.1    
 SAMEA3431348_01661 (Nana_3)   Streptococcus pneumoniae 2245STDY6106635 VGM77445.1    
 SAMEA3431348_01275 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106635 VGM77066.1    
 SAMEA3431348_01275 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106635 VGM77066.1    
 SAMEA3431348_01655 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106635 VGM77439.1    
 SAMEA3431348_01655 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106635 VGM77439.1    
 SAMEA3431351_01556 (NanB)   Streptococcus pneumoniae 2245STDY6106637 VFI28040.1    
 SAMEA3431351_01556 (NanB)   Streptococcus pneumoniae 2245STDY6106637 VFI28040.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6106637 VFI28070.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106751 VFI23650.1    
 SAMEA3431383_01533 (NanB)   Streptococcus pneumoniae 2245STDY6106751 VFI23614.1    
 SAMEA3431383_01533 (NanB)   Streptococcus pneumoniae 2245STDY6106751 VFI23614.1    
 SAMEA3713867_01281 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178787 VFI38112.1    
 SAMEA3713867_01281 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178787 VFI38112.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178787 VFI40904.1    
 SAMEA3713867_01662 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178787 VFI40858.1    
 SAMEA3713867_01662 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178787 VFI40858.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178826 VFI44829.1    
 SAMEA3713960_01711 (NanB)   Streptococcus pneumoniae 2245STDY6178826 VFI44784.1    
 SAMEA3713960_01711 (NanB)   Streptococcus pneumoniae 2245STDY6178826 VFI44784.1    
 SAMEA3713964_01314 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178828 VFI53507.1    
 SAMEA3713964_01314 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178828 VFI53507.1    
 SAMEA3713964_01618 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178828 VFI54416.1    
 SAMEA3713964_01618 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178828 VFI54416.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178828 VFI54437.1    
 SAMEA3714019_01609 (NanB)   Streptococcus pneumoniae 2245STDY6178854 VGM82218.1    
 SAMEA3714019_01609 (NanB)   Streptococcus pneumoniae 2245STDY6178854 VGM82218.1    
 SAMEA3714019_01615 (Nana_2)   Streptococcus pneumoniae 2245STDY6178854 VGM82236.1    
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