Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5538); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (5293) Archaea (1) Bacteria (4848) Eukaryota (404) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | ... | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF (fragment)   uncultured bacterium APO32020.1    
 GH33, Sialidase   uncultured bacterium VDS02392.1    
 ORF (fragment)   uncultured bacterium fosmid pJB148G3 AIF26887.1    
 sialidase   uncultured bacterium Rlip1 ACM91104.1 C0K074  
 CMV30_05015   Verrucomicrobia bacterium HZ-65 ATC63364.1    
 CMV30_08310   Verrucomicrobia bacterium HZ-65 ATC63952.1    
 IMCC26134_04605   Verrucomicrobia bacterium IMCC26134 AKC83918.1    
 PL85_10365   Vibrio anguillarum DSM 21597 AQM03037.1    
 PL85_10365   Vibrio anguillarum DSM 21597 AQM03037.1    
 PO29_12530   Vibrio anguillarum HI610 AQM17087.1    
 PO29_12530   Vibrio anguillarum HI610 AQM17087.1    
 DYL72_11630   Vibrio anguillarum J360 AZS25596.1    
 DYL72_11630   Vibrio anguillarum J360 AZS25596.1    
 CMV05_04215   Vibrio anguillarum VIB12 ATC56928.1    
 CMV05_04215   Vibrio anguillarum VIB12 ATC56928.1    
 CK207_04320   Vibrio anguillarum VIB43 ASW80374.1    
 CK207_04320   Vibrio anguillarum VIB43 ASW80374.1    
 VAB027_2456 (NanH)   Vibrio cholerae 10432-62 AKB08334.1    
 VAB027_2456 (NanH)   Vibrio cholerae 10432-62 AKB08334.1    
 neuraminidase (NanH)   Vibrio cholerae 13 AIL52586.1    
 neuraminidase (NanH)   Vibrio cholerae 13 AIL52586.1    
 NanH   Vibrio cholerae 17674 QBJ27574.1    
 NanH   Vibrio cholerae 17674 QBJ27574.1    
 NanH   Vibrio cholerae 18470 QBJ27573.1    
 NanH   Vibrio cholerae 18470 QBJ27573.1    
 EZZ25_09390   Vibrio cholerae 20000 QBJ29517.1    
 EZZ25_09390   Vibrio cholerae 20000 QBJ29517.1    
 EN18_12065   Vibrio cholerae 2012EL-2176 AIT29775.1    
 EN18_12065   Vibrio cholerae 2012EL-2176 AIT29775.1    
 BBB50_05755   Vibrio cholerae 2740-80 ANR87208.1    
 BBB50_05755   Vibrio cholerae 2740-80 ANR87208.1    
 sialidase / neuraminidase (NanH;VcNA;VCSA) 3.2.1.18 Vibrio cholerae 569B 395 AAA27546.1 P37060 1KIT[A]
1W0O[A]
1W0P[A]
6EKS[A]
6EKU[A]
 sialidase / neuraminidase (NanH;VcNA;VCSA) 3.2.1.18 Vibrio cholerae 569B 395 AAA27546.1 P37060 1KIT[A]
1W0O[A]
1W0P[A]
6EKS[A]
6EKU[A]
 C1H56_07940   Vibrio cholerae A1552 AUR70019.1    
 C1H56_07940   Vibrio cholerae A1552 AUR70019.1    
 VCA1552_01564 (NanH)   Vibrio cholerae A1552 AVL22978.1    
 VCA1552_01564 (NanH)   Vibrio cholerae A1552 AVL22978.1    
 A1552VC_01566 (NanH)   Vibrio cholerae A1552 AWB74302.1    
 A1552VC_01566 (NanH)   Vibrio cholerae A1552 AWB74302.1    
 NanH   Vibrio cholerae AMAZONIA 3509 AAW31751.2 Q5IB64
Q5IB64
 
 NanH   Vibrio cholerae AMAZONIA 3509 AAW31751.2
AAW31751.1
Q5IB64
Q5IB64
 
 neuraminidase   Vibrio cholerae C5 APF49319.1    
 neuraminidase   Vibrio cholerae C5 APF49319.1    
 ASZ81_01775   Vibrio cholerae CRC1106 APF56916.1    
 ASZ81_01775   Vibrio cholerae CRC1106 APF56916.1    
 neuraminidase   Vibrio cholerae CRC711 APF53177.1    
 neuraminidase   Vibrio cholerae CRC711 APF53177.1    
 ASZ88_01723 (NanH)   Vibrio cholerae E1320 APF68105.1    
 ASZ88_01723 (NanH)   Vibrio cholerae E1320 APF68105.1    
 EEL44_12020   Vibrio cholerae E4 AYV09698.1    
 EEL44_12020   Vibrio cholerae E4 AYV09698.1    
 neuraminidase   Vibrio cholerae E506 APF60361.1    
 neuraminidase   Vibrio cholerae E506 APF60361.1    
 CSW01_08950   Vibrio cholerae E7946 ATQ46817.1    
 CSW01_08950   Vibrio cholerae E7946 ATQ46817.1    
 neuraminidase   Vibrio cholerae E9120 APF71815.1    
 neuraminidase   Vibrio cholerae E9120 APF71815.1    
 A6J62_08325   Vibrio cholerae FDAARGOS_223 ARB80595.1    
 A6J62_08325   Vibrio cholerae FDAARGOS_223 ARB80595.1    
 FORC73_1040   Vibrio cholerae FORC_073 AYC05024.1    
 FORC73_1040   Vibrio cholerae FORC_073 AYC05024.1    
 neuraminidase   Vibrio cholerae IEC224 AFC58601.1    
 neuraminidase   Vibrio cholerae IEC224 AFC58601.1    
 VCLMA_A1545   Vibrio cholerae LMA3984-4 AEA78761.1    
 VCLMA_A1545   Vibrio cholerae LMA3984-4 AEA78761.1    
 neuraminidase   Vibrio cholerae M2140 APF75003.1    
 neuraminidase   Vibrio cholerae M2140 APF75003.1    
 neuraminidase (NanH)   Vibrio cholerae M66-2 ACP06029.1 C3LNA3  
 neuraminidase (NanH)   Vibrio cholerae M66-2 ACP06029.1 C3LNA3  
 VCD_002587   Vibrio cholerae MJ-1236 ACQ60753.1 C3NPP4  
 VCD_002587   Vibrio cholerae MJ-1236 ACQ60753.1 C3NPP4  
 MS6_1556   Vibrio cholerae MS6 BAP03211.1    
 MS6_1556   Vibrio cholerae MS6 BAP03211.1    
 N16961_VC01090 (NanH)   Vibrio cholerae N16961 AWA78170.1    
 N16961_VC01090 (NanH)   Vibrio cholerae N16961 AWA78170.1    
 neuraminidase   Vibrio cholerae NCTC5395 APF79274.1    
 neuraminidase   Vibrio cholerae NCTC5395 APF79274.1    
 neuraminidase (fragment)   Vibrio cholerae NCTC9420 APF83226.1    
 neuraminidase (fragment)   Vibrio cholerae NCTC9420 APF83227.1    
 C4E16_06200   Vibrio cholerae O1 biovar El Tor HC1037 AVH51954.1    
 C4E16_06200   Vibrio cholerae O1 biovar El Tor HC1037 AVH51954.1    
 neuraminidase (NanH)   Vibrio cholerae O1 biovar El Tor R-5879 AND74814.1    
 neuraminidase (NanH)   Vibrio cholerae O1 biovar El Tor R-5879 AND74814.1    
 VC1784   Vibrio cholerae O1 biovar El Tor str. N16961 AAF94933.1
NP_231419.1
P0C6E9  
 VC1784   Vibrio cholerae O1 biovar El Tor str. N16961 AAF94933.1
NP_231419.1
P0C6E9  
 neuraminidase (NanH)   Vibrio cholerae O1 str. 2010EL-1786 AET26878.1    
 neuraminidase (NanH)   Vibrio cholerae O1 str. 2010EL-1786 AET26878.1    
 N900_05420   Vibrio cholerae O1 str. KW3 ALJ63797.1    
 N900_05420   Vibrio cholerae O1 str. KW3 ALJ63797.1    
 VC0395_A1381   Vibrio cholerae O395 ABQ19703.1
ACP09894.1
A5F7A4  
 VC0395_A1381   Vibrio cholerae O395 ABQ19703.1
ACP09894.1
A5F7A4  
 NanH   Vibrio cholerae R-13169 AVK79099.1    
 NanH   Vibrio cholerae R-13169 AVK79099.1    
 NanH   Vibrio cholerae R-17917 AVK79100.1    
 NanH   Vibrio cholerae R-17917 AVK79100.1    
 NanH   Vibrio cholerae R-17918 QBJ27575.1    
 NanH   Vibrio cholerae R-17918 QBJ27575.1    
 NanH   Vibrio cholerae R-18252 AVK79101.1    
 NanH   Vibrio cholerae R-18252 AVK79101.1    
 NanH   Vibrio cholerae R-18367 AVK79102.1    
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