Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5538); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (5293) Archaea (1) Bacteria (4848) Eukaryota (404) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | ... | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | ... | 50 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SL103_07905 (fragment)   Streptomyces lydicus 103 AOP46171.1    
 DDE74_33435   Streptomyces lydicus WYEC 108 AZS76819.1    
 neuraminidase   Streptomyces malaysiensis DSM 4137 ATL86407.1
QDL70019.1
   
 SMALA_6927   Streptomyces malaysiensis DSM 4137 ATL87147.1
QDL69382.1
   
 DNK48_32465   Streptomyces malaysiensis DSM 4137 QDL73269.1
ATL82417.1
   
 BBN63_34045   Streptomyces niveus SCSIO 3406 AQU70446.1    
 BBN63_01630   Streptomyces niveus SCSIO 3406 AQU65158.1    
 SNOD_11480   Streptomyces nodosus ATCC 14899 AJE40603.1    
 neuraminidase   Streptomyces noursei ATCC 11455 ANZ15411.1    
 BC342_02930   Streptomyces pactum KLBMP 5084 AOW85646.1    
 Spa2297_27290   Streptomyces parvulus 2297 ANJ10358.1    
 LK06_009320 (fragment)   Streptomyces pluripotens MUSC 135 ARP70133.1    
 LK07_10435 (fragment)   Streptomyces pluripotens MUSC 137 ASN24392.1    
 Sfla_1120   Streptomyces pratensis ATCC 33331 ADW02574.1 C9NF48  
 SPRI_6322   Streptomyces pristinaespiralis HCCB 10218 ALC24628.1    
 BFF78_29875   Streptomyces puniciscabiei TW1S1 AOR34698.1    
 BFF78_08635   Streptomyces puniciscabiei TW1S1 AOR31101.1    
 BFF78_28390   Streptomyces puniciscabiei TW1S1 AOR34447.1    
 A4E84_11690   Streptomyces qaidamensis S10(2016) AMW10120.1    
 A4E84_33700   Streptomyces qaidamensis S10(2016) AMW14014.1    
 M271_35050   Streptomyces rapamycinicus NRRL 5491 AGP58418.1    
 M271_07500   Streptomyces rapamycinicus NRRL 5491 AGP53120.1    
 neuraminidase   Streptomyces rapamycinicus NRRL 5491 AGP54140.1    
 TUE45_07154 (Neda_3)   Streptomyces reticuli CUW32405.1    
 TUE45_03121 (Neda_2)   Streptomyces reticuli CUW28387.1    
 TUE45_02825 (Neda_1)   Streptomyces reticuli CUW28095.1    
 CTZ40_29530   Streptomyces rimosus WT5260 QDA07275.1    
 CTZ40_06710   Streptomyces rimosus WT5260 QDA03471.1    
 SRO_4931   Streptomyces rochei 7434AN4 BBC96107.1    
 SRO_1359   Streptomyces rochei 7434AN4 BBC92535.1    
 A7J05_25630   Streptomyces silaceus ACCC40021 APY88614.1    
 A7J05_05955   Streptomyces silaceus ACCC40021 APY85328.1    
 CGL27_15120   Streptomyces sp. 11-1-2 ASQ94228.1    
 CGL27_36225   Streptomyces sp. 11-1-2 ASQ97747.1    
 CGL27_41180   Streptomyces sp. 11-1-2 ASQ98581.1    
 SAMN05428941_6626   Streptomyces sp. 2114.2 SDT79140.1    
 SAMN06272775_5075   Streptomyces sp. 2323.1 SOE14111.1    
 SAMN06272775_6207   Streptomyces sp. 2323.1 SOE15281.1    
 SAMN06272775_1119   Streptomyces sp. 2323.1 SOE10071.1    
 SAMN05444521_7759   Streptomyces sp. 3214.6 SHI51548.1    
 ASR50_28895   Streptomyces sp. 4F ALV53033.1    
 neuraminidase   Streptomyces sp. 769 AJC54865.1    
 T261_6984   Streptomyces sp. A02 AJT68586.1    
 neuraminidase   Streptomyces sp. A02 AJT63325.1    
 T261_5894   Streptomyces sp. A02 AJT67510.3
AJT67510.1
AJT67510.2
   
 EES41_21150 (NedA)   Streptomyces sp. ADI95-16 AYV29221.1    
 C4J65_29800   Streptomyces sp. CB09001 AXL92020.1    
 C4J65_31815   Streptomyces sp. CB09001 AXL92354.1    
 NI25_34220   Streptomyces sp. CCM_MD2014 AIV37956.1    
 AS200_10380   Streptomyces sp. CdTB01 ALV38485.1    
 AS200_29915   Streptomyces sp. CdTB01 ALV35791.1    
 AS200_31520   Streptomyces sp. CdTB01 ALV36071.1    
 ABE83_13020   Streptomyces sp. CFMR 7 ALC27916.1    
 neuraminidase   Streptomyces sp. CMB-StM0423 AUH43077.1    
 CXR04_30015   Streptomyces sp. CMB-StM0423 AUH43847.1    
 AA958_27020   Streptomyces sp. CNQ-509 AKH85286.1    
 AA958_04495   Streptomyces sp. CNQ-509 AKH81573.1    
 neuraminidase   Streptomyces sp. CNQ-509 AKH82377.1    
 SFR_6663   Streptomyces sp. FR-008 ALM43278.1    
 C1703_10640 (Neda1)   Streptomyces sp. Go-475 AXE85460.1    
 C1703_33275 (Neda2)   Streptomyces sp. Go-475 AXE89910.1    
 D1J63_32895   Streptomyces sp. KPB2 AZM79219.1    
 CFP59_02439 (Neda_1)   Streptomyces sp. M56 AUA10340.1    
 CFP59_01742   Streptomyces sp. M56 AUA09652.1    
 CFP59_06452 (Neda_2)   Streptomyces sp. M56 AUA14274.1    
 EJ357_13195   Streptomyces sp. MK-45 AZQ34322.1    
 EJ357_15115   Streptomyces sp. MK-45 AZQ34644.1    
 EJ357_01525   Streptomyces sp. MK-45 AZQ32299.1    
 EJ357_39230   Streptomyces sp. MK-45 AZQ38742.1    
 STRMOE7_31410   Streptomyces sp. MOE7 ARH94053.1    
 STRMOE7_07000   Streptomyces sp. MOE7 ARH90086.1    
 DKG71_12975   Streptomyces sp. NEAU-S7GS2 AWN26925.1    
 DKG71_36330   Streptomyces sp. NEAU-S7GS2 AWN32487.1    
 F750_5720   Streptomyces sp. PAMC 26508 AGJ58149.1    
 QR97_03235   Streptomyces sp. PBH53 AKN68959.1    
 QR97_07950   Streptomyces sp. PBH53 AKN69768.1    
 QR97_13920   Streptomyces sp. PBH53 AKN70764.1    
 FNV59_21225   Streptomyces sp. RLB1-8 QDO60332.1    
 FNV59_19430   Streptomyces sp. RLB1-8 QDO60028.1    
 FNV59_42780   Streptomyces sp. RLB1-8 QDO63946.1    
 FNV58_21865   Streptomyces sp. RLB1-9 QDN98310.1    
 FNV58_20050   Streptomyces sp. RLB1-9 QDN98009.1    
 FNV58_43795   Streptomyces sp. RLB1-9 QDO01967.1    
 FNV62_19285   Streptomyces sp. RLB3-17 QDO40030.1    
 FNV62_17500   Streptomyces sp. RLB3-17 QDO39733.1    
 FNV62_41900   Streptomyces sp. RLB3-17 QDO43783.1    
 FNV60_18985   Streptomyces sp. RLB3-5 QDO50092.1    
 FNV60_40530   Streptomyces sp. RLB3-5 QDO53701.1    
 FNV60_17185   Streptomyces sp. RLB3-5 QDO49787.1    
 FNV61_20200   Streptomyces sp. RLB3-6 QDN87642.1    
 FNV61_43535   Streptomyces sp. RLB3-6 QDN91475.1    
 FNV61_18290   Streptomyces sp. RLB3-6 QDN87328.1    
 FNV64_43915   Streptomyces sp. S1A1-7 QDN81578.1    
 FNV64_22245   Streptomyces sp. S1A1-7 QDN77966.1    
 FNV66_42050   Streptomyces sp. S1D4-14 QDN71246.1    
 FNV66_18935   Streptomyces sp. S1D4-14 QDN67378.1    
 FNV66_20730   Streptomyces sp. S1D4-14 QDN67679.1    
 FNV67_19340   Streptomyces sp. S1D4-20 QDN57203.1    
 FNV67_21535   Streptomyces sp. S1D4-20 QDN57582.1    
 FNV67_43200   Streptomyces sp. S1D4-20 QDN61192.1    
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