Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5863); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (5623) Archaea (1) Bacteria (5166) Eukaryota (415) Viruses (35) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | ... | 53 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GBSCOH1_1727   Streptococcus agalactiae COH1 CDN67193.1    
 BB161_10290   Streptococcus agalactiae CUGBS591 ASA80531.1    
 CUGBS08_01861 (Nana_2)   Streptococcus agalactiae CU_GBS_08 AMQ15409.1    
 CUGBS98_01797 (Nana_2)   Streptococcus agalactiae CU_GBS_98 AMQ17400.1    
 A6J82_03365   Streptococcus agalactiae FDAARGOS_254 ARC44456.1    
 EGX82_07260   Streptococcus agalactiae FDAARGOS_512 AYZ23620.1    
 FOB77_05485   Streptococcus agalactiae FDAARGOS_669 QET35145.1    
 FOB78_10765   Streptococcus agalactiae FDAARGOS_670 QET54644.1    
 A9256_09310   Streptococcus agalactiae FWL1402 ANR97840.1    
 AOY37_09505   Streptococcus agalactiae GBS ST-1 ALP88339.1    
 AV644_09270   Streptococcus agalactiae GBS-M002 APS25822.1    
 DK41_10055   Streptococcus agalactiae GBS1-NY AIK72457.1    
 DK42_10410   Streptococcus agalactiae GBS2-NM AIK74589.1    
 DX05_10030   Streptococcus agalactiae GBS6 AIK76564.1    
 GBS85147_1819   Streptococcus agalactiae GBS85147 AKI58240.1    
 A964_1791 (Neu1)   Streptococcus agalactiae GD201008-001 AFS46548.1    
 GX064_09090   Streptococcus agalactiae GX064 AKU00746.1    
 SAH002_09620   Streptococcus agalactiae H002 AKU04382.1    
 SAHN016_09170   Streptococcus agalactiae HN016 AKT96870.1    
 SAGS_1996 (Nana_2)   Streptococcus agalactiae HU-GS5823 BBG33677.1    
 MSA_20180   Streptococcus agalactiae ILRI005 CCW40873.1    
 SAIL_19510   Streptococcus agalactiae ILRI112 CCW42962.1    
 NCTC11930_00283 (Nana_2)   Streptococcus agalactiae NCTC11930 SQF30124.1    
 NCTC13947_00325 (Nana_1)   Streptococcus agalactiae NCTC13947 VEJ27040.1    
 NCTC13949_01869 (Nana_2)   Streptococcus agalactiae NCTC13949 VEJ13613.1    
 NCTC8184_00434 (Nana_1)   Streptococcus agalactiae NCTC8184 VED64464.1    
 NCTC8187_01868 (Nana_2)   Streptococcus agalactiae NCTC8187 SQG27151.1    
 Gbs1919   Streptococcus agalactiae NEM316 CAD47578.1
NP_736353.1
   
 EN72_10135   Streptococcus agalactiae NGBS061 AIF87430.1    
 AMM49_09330   Streptococcus agalactiae NGBS128 AMD33094.1    
 AMR84_09690   Streptococcus agalactiae NGBS357 AOF51826.1    
 EN73_09225   Streptococcus agalactiae NGBS572 AIF89367.1    
 DLM82_09790   Streptococcus agalactiae PLGBS13 QDK30916.1    
 DSN71_09450   Streptococcus agalactiae S73 AXC18157.1    
 SaSA375_1644 (fragment)   Streptococcus agalactiae SA375 AUP38884.1    
 SaSA375_1645 (fragment)   Streptococcus agalactiae SA375 AUP38885.1    
 SaSA623_1643 (fragment)   Streptococcus agalactiae SA623 AUP40620.1    
 SaSA623_1644 (fragment)   Streptococcus agalactiae SA623 AUP40621.1    
 SaSA627_1645 (fragment)   Streptococcus agalactiae SA627 AUP42348.1    
 SaSA627_1644 (fragment)   Streptococcus agalactiae SA627 AUP42347.1    
 B2G84_09740   Streptococcus agalactiae Sag158 AQY27133.1    
 DY328_02910   Streptococcus agalactiae Sag27 AXO11217.1    
 B1H24_10200   Streptococcus agalactiae Sag37 AQY25110.1    
 AMD29_09470   Streptococcus agalactiae SG-M1 ALB16795.1    
 BB194_09675   Streptococcus agalactiae SG-M158 ASA84642.1    
 BB197_09675   Streptococcus agalactiae SG-M163 ASA82588.1    
 BB164_10280   Streptococcus agalactiae SG-M25 ASA90889.1    
 BB268_09675   Streptococcus agalactiae SG-M29 ASA88743.1    
 BB165_09520   Streptococcus agalactiae SG-M4 ASA99746.1    
 BB313_09670   Streptococcus agalactiae SG-M50 ASA86689.1    
 BB162_09670   Streptococcus agalactiae SG-M6 ASA95066.1    
 BB159_09705   Streptococcus agalactiae SG-M8 ASA93016.1    
 CWQ22_09215   Streptococcus agalactiae SGEHI2015-107 ATZ83650.1    
 CWQ23_09330   Streptococcus agalactiae SGEHI2015-113 ATZ90122.1    
 CWQ20_09480   Streptococcus agalactiae SGEHI2015-25 ATZ85654.1    
 CWQ21_09785   Streptococcus agalactiae SGEHI2015-95 ATZ92169.1    
 RDF_1823   Streptococcus agalactiae SS1 AKI96238.1    
 DNK17_01865   Streptococcus agalactiae TFJ0901 AZL55248.1    
 BBP08_10290   Streptococcus agalactiae WC1535 AOQ21565.1    
 YM001_09075   Streptococcus agalactiae YM001 AKT98804.1    
 neuraminidase (Nana_2)   Streptococcus australis NCTC5338 VTS72320.1    
 SAMEA5186854_01848 (NanB)   Streptococcus canis B700072 VTR80708.1    
 SEQ_1612   Streptococcus equi subsp. equi 4047 CAW94606.1 C0MAP0  
 SE071780_01638   Streptococcus equi subsp. equi ATCC 39506 ASB97227.1    
 NCTC12091_01449 (Nana_2)   Streptococcus equi subsp. equi NCTC12091 VED85992.1    
 NCTC9682_01705 (Nana_2)   Streptococcus equi subsp. equi NCTC9682 VEH34625.1    
 SeseC_01852   Streptococcus equi subsp. zooepidemicus ATCC 35246 AEJ25722.1    
 Q426_01975   Streptococcus equi subsp. zooepidemicus CY AIA68611.1    
 SZO_05310   Streptococcus equi subsp. zooepidemicus H70 CAW98510.1    
 Sez_1425 (NanA)   Streptococcus equi subsp. zooepidemicus MGCS10565 ACG62759.1 B4U442  
 NCTC11606_01420 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC11606 SQF54428.1    
 NCTC11824_01433 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC11824 SQG17617.1    
 NCTC11854_01901 (Nana_2) (fragment)   Streptococcus equi subsp. zooepidemicus NCTC11854 VTP93991.1    
 NCTC11854_01903 (Nana_3) (fragment)   Streptococcus equi subsp. zooepidemicus NCTC11854 VTP94001.1    
 NCTC11854_01902 (fragment)   Streptococcus equi subsp. zooepidemicus NCTC11854 VTP93997.1    
 NCTC12090_01514 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC12090 SQF06020.1    
 NCTC4675_01456 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC4675 VTS32517.1    
 NCTC6176_01454 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC6176 SQF82073.1    
 NCTC6180_00298 (Nana_1)   Streptococcus equi subsp. zooepidemicus NCTC6180 VEF05361.1    
 NCTC7022_01491 (Nana_2)   Streptococcus equi subsp. zooepidemicus NCTC7022 SQE96358.1    
 BMF34_09145   Streptococcus iniae 89353 APD32625.1    
 neuraminidase (NeuA) (fragment)   Streptococcus iniae DGX07 AMW63819.1    
 CTW00_00337 (Nana_2)   Streptococcus iniae FP5228 ATX38579.1    
 D5R92_04480   Streptococcus iniae GX005 AYB01718.1    
 DQ08_09165   Streptococcus iniae ISET0901 AHY16600.1    
 DW64_09145   Streptococcus iniae ISNO AHY18466.1    
 neuraminidase (NanA)   Streptococcus iniae QMA0248 ASL35592.1    
 K710_1941   Streptococcus iniae SF1 AGM99689.1    
 D5R90_05890   Streptococcus iniae YM011 AYB03796.1    
 SI82_09135   Streptococcus iniae YSFST01-82 AJG26732.1    
 sialidase 3.2.1.18 Streptococcus intermedius ATCC 27335 BAJ15290.1 E0CZJ4  
 neuraminidase (NanA)   Streptococcus intermedius B196 AGU75433.1    
 neuraminidase (NanA)   Streptococcus intermedius C270 AGU77248.1    
 A6J72_05350   Streptococcus intermedius FDAARGOS_233 AVH83551.1    
 SCIM_0012 (NanA)   Streptococcus intermedius JTH08 BAM22666.1    
 RN88_09240   Streptococcus intermedius KCOM 1545 ALF28645.1    
 neuraminidase (Nana_1)   Streptococcus intermedius NCTC11324 SQH51041.1    
 SITYG_00150 (NanA)   Streptococcus intermedius TYG1620 BAW16002.1    
 SAMEA4412692_01537 (NanB) (fragment)   Streptococcus merionis NCTC13788 SNU89542.1    
 smi_0601 (NanA)   Streptococcus mitis B6 CBJ21850.1 D3H7K8  
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