Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5863); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (5623) Archaea (1) Bacteria (5166) Eukaryota (415) Viruses (35) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | ... | 53 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CDO26_32785   Sinorhizobium meliloti M270 ASP89313.1    
 CDO27_29905   Sinorhizobium meliloti Rm41 ASP82894.1    
 BN406_06513   Sinorhizobium meliloti Rm41 CCM72795.1    
 DU99_32555   Sinorhizobium meliloti RMO17 AIM03892.1    
 SMRU11_11270   Sinorhizobium meliloti RU11/001 ARS69155.1    
 SM11_pD1447   Sinorhizobium meliloti SM11 AEH84279.1    
 CDO28_31335   Sinorhizobium meliloti T073 ASP76368.1    
 CDO29_25455   Sinorhizobium meliloti USDA1021 ASP69406.1    
 CDO30_26180   Sinorhizobium meliloti USDA1106 ASP63026.1    
 CDO31_32085   Sinorhizobium meliloti USDA1157 ASP56521.1    
 SS05631_b56710   Sinorhizobium sp. CCBAU 05631 ASY59763.1    
 BSY16_5469   Sinorhizobium sp. RAC02 AOF93952.1    
 CA265_10530   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS40061.1    
 CA265_08490   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS39685.1    
 CA265_04850   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS39041.1    
 neuraminidase   Sphingobacterium daejeonense NCTC13534 VTP88824.1    
 NCTC13534_05174 (fragment)   Sphingobacterium daejeonense NCTC13534 VTQ06975.1    
 neuraminidase (fragment)   Sphingobacterium daejeonense NCTC13534 VTQ07360.1    
 neuraminidase (fragment)   Sphingobacterium daejeonense NCTC13534 VTQ07356.1    
 NCTC13534_05173 (NedA) (fragment)   Sphingobacterium daejeonense NCTC13534 VTQ06971.1    
 neuraminidase   Sphingobacterium mizutaii NCTC12149 SNV41454.1    
 SAMEA4412673_03723 (Neda_2)   Sphingobacterium mizutaii NCTC12149 SNV61629.1    
 E2P86_15505   Sphingobacterium psychroaquaticum SJ-25 QBQ42474.1    
 E2P86_07210   Sphingobacterium psychroaquaticum SJ-25 QBQ40946.1    
 Sph21_1902   Sphingobacterium sp. 21 ADZ78462.1    
 Sph21_2317   Sphingobacterium sp. 21 ADZ78871.1    
 Sph21_4294   Sphingobacterium sp. 21 ADZ80817.1    
 Sph21_4587   Sphingobacterium sp. 21 ADZ81102.1    
 Sph21_4589   Sphingobacterium sp. 21 ADZ81104.1    
 Sph21_5174   Sphingobacterium sp. 21 ADZ81663.1    
 BV902_25750   Sphingobacterium sp. B29 APU99302.1    
 BV902_06650   Sphingobacterium sp. B29 APU96056.1    
 BV902_05075   Sphingobacterium sp. B29 APU95785.1    
 E3D81_00315   Sphingobacterium sp. CZ-2 QBR10704.1    
 E3D81_00320   Sphingobacterium sp. CZ-2 QBR10705.1    
 E3D81_09360   Sphingobacterium sp. CZ-2 QBR12354.1    
 E3D81_00305   Sphingobacterium sp. CZ-2 QBR10702.1    
 KO02_01165   Sphingobacterium sp. ML3W AIM35425.1    
 BN1088_1433106   Sphingobacterium sp. PM2-P1-29 CDT04528.1    
 BN1088_1433637   Sphingobacterium sp. PM2-P1-29 CDT10302.1    
 neuraminidase   Sphingobacterium thalpophilum NCTC11429 VTR38936.1    
 neuraminidase   Sphingobacterium thalpophilum NCTC11429 VTR31576.1    
 NCTC11429_04303 (Neda_4)   Sphingobacterium thalpophilum NCTC11429 VTR51280.1    
 NCTC11429_02646 (Neda_2)   Sphingobacterium thalpophilum NCTC11429 VTR42139.1    
 TS85_22700   Sphingomonas hengshuiensis WHSC-8 AJP74009.1    
 BJP26_06150   Sphingomonas melonis TY AOW23209.1    
 CP552_13380   Sphingomonas melonis ZJ26 ATI56644.1    
 DRN02_016510   Sphingomonas paucimobilis AIMST S2 QBE93421.1    
 BRX40_04735   Sphingomonas sp. ABOJV APR51829.1    
 CVN68_12580   Sphingomonas sp. Cra20 ATY32708.1    
 MC45_11420   Sphingomonas taxi ATCC 55669 AIT06881.1    
 Slin_2629   Spirosoma linguale DSM 74 ADB38646.1 D2QHI6  
 Slin_1808   Spirosoma linguale DSM 74 ADB37853.1 D2QR01  
 Slin_1864   Spirosoma linguale DSM 74 ADB37909.1 D2QBN0  
 AWR27_14935   Spirosoma montaniterrae DY10 AQG82511.1    
 CWM47_30485   Spirosoma pollinicola HA7 AUD05793.1    
 SD10_13370   Spirosoma radiotolerans DG5A AKD55743.1    
 neuraminidase   Spirosoma radiotolerans DG5A AKD54406.1    
 EXU85_08310   Spirosoma sp. KCTC 42546 QDK78612.1    
 EXU85_25400   Spirosoma sp. KCTC 42546 QDK81765.1    
 EXU85_19365   Spirosoma sp. KCTC 42546 QDK80650.1    
 Snas_5835   Stackebrandtia nassauensis DSM 44728 ADD45465.1 D3PZ36  
 NCTC5661_01624 (NanB)   Staphylococcus aureus NCTC5661 VED69667.1    
 B5P37_01880   Staphylococcus lutrae ATCC 700373 ARJ50156.1    
 A6M57_9160   Staphylococcus pseudintermedius 063228 ANS90148.1    
 A9I65_09180   Staphylococcus pseudintermedius 081661 ANQ89509.1    
 EW135_05740   Staphylococcus pseudintermedius 49_44 QBG68192.1    
 EW137_01005   Staphylococcus pseudintermedius 51_92 QBG69669.1    
 EW136_04535   Staphylococcus pseudintermedius 53_60 QBG73939.1    
 EW134_09850   Staphylococcus pseudintermedius 53_88 QBG76271.1    
 SPS5912_08930   Staphylococcus pseudintermedius 5912 ASQ51079.1    
 SPSE_1829   Staphylococcus pseudintermedius ED99 ADX77079.1    
 SPSE_1611 (NanB)   Staphylococcus pseudintermedius ED99 ADX76869.1    
 D8L98_12070   Staphylococcus pseudintermedius G3C4 AYG57386.1    
 SPSINT_0694   Staphylococcus pseudintermedius HKU10-03 ADV05223.1    
 A9I66_08810   Staphylococcus pseudintermedius NA45 ANQ82112.1    
 GSP_17150   Staphylococcus pseudintermedius SP79 BBH74521.1    
 neuraminidase   Staphylococcus sciuri FDAARGOS_285 ASE35516.1    
 A7X73_12570   Staphylococcus simulans MR1 AWI02704.1    
 A9958_12680   Staphylococcus simulans MR2 AWG19756.1    
 BI282_12675   Staphylococcus simulans MR3 AVO03208.1    
 BI283_12690   Staphylococcus simulans MR4 AVO06163.1    
 SAMEA4384403_01390 (Nana_2)   Staphylococcus stepanovicii NCTC13839 SNV68384.1    
 Smon_0005   Streptobacillus moniliformis DSM 12112 ACZ00505.1 D1AW29  
 Smon_1211   Streptobacillus moniliformis DSM 12112 ACZ01666.1 D1AVA6  
 CEP89_04210   Streptobacillus moniliformis FDAARGOS_310 AVL43077.1    
 CEP89_05700   Streptobacillus moniliformis FDAARGOS_310 AVL43335.1    
 BQ8897_BM110_01966   Streptococcus agalactiae SIW58426.1    
 BSA_19490   Streptococcus agalactiae 09mas018883 CCW38715.1    
 SAG1932   Streptococcus agalactiae 2603V/R AAN00794.1
NP_688921.1
   
 DKY66_09940   Streptococcus agalactiae 32790-3A QDI66930.1    
 neuraminidase   Streptococcus agalactiae 874391 ASZ02150.1    
 SAK_1891 (partial)   Streptococcus agalactiae A909 ABA45464.1    
 CCZ24_00400   Streptococcus agalactiae B105 AWZ35352.1    
 CDH81_05630   Streptococcus agalactiae B111 AWZ34269.1    
 CDH84_08395   Streptococcus agalactiae B507 AWZ32765.1    
 CDH83_08855   Streptococcus agalactiae B508 AWZ30760.1    
 CDH85_04050   Streptococcus agalactiae B509 AWZ27847.1    
 GT95_09720   Streptococcus agalactiae C001 ASI66881.1    
 W903_1868   Streptococcus agalactiae CNCTC 10/84 AIX05533.1    
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