Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5538); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (5293) Archaea (1) Bacteria (4848) Eukaryota (404) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | ... | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | ... | 50 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CVN68_12580   Sphingomonas sp. Cra20 ATY32708.1    
 MC45_11420   Sphingomonas taxi ATCC 55669 AIT06881.1    
 Slin_2629   Spirosoma linguale DSM 74 ADB38646.1 D2QHI6  
 Slin_1808   Spirosoma linguale DSM 74 ADB37853.1 D2QR01  
 Slin_1864   Spirosoma linguale DSM 74 ADB37909.1 D2QBN0  
 AWR27_14935   Spirosoma montaniterrae DY10 AQG82511.1    
 CWM47_30485   Spirosoma pollinicola HA7 AUD05793.1    
 SD10_13370   Spirosoma radiotolerans DG5A AKD55743.1    
 neuraminidase   Spirosoma radiotolerans DG5A AKD54406.1    
 EXU85_08310   Spirosoma sp. KCTC 42546 QDK78612.1    
 EXU85_25400   Spirosoma sp. KCTC 42546 QDK81765.1    
 EXU85_19365   Spirosoma sp. KCTC 42546 QDK80650.1    
 Snas_5835   Stackebrandtia nassauensis DSM 44728 ADD45465.1 D3PZ36  
 NCTC5661_01624 (NanB)   Staphylococcus aureus NCTC5661 VED69667.1    
 B5P37_01880   Staphylococcus lutrae ATCC 700373 ARJ50156.1    
 A6M57_9160   Staphylococcus pseudintermedius 063228 ANS90148.1    
 A9I65_09180   Staphylococcus pseudintermedius 081661 ANQ89509.1    
 EW135_05740   Staphylococcus pseudintermedius 49_44 QBG68192.1    
 EW137_01005   Staphylococcus pseudintermedius 51_92 QBG69669.1    
 EW136_04535   Staphylococcus pseudintermedius 53_60 QBG73939.1    
 EW134_09850   Staphylococcus pseudintermedius 53_88 QBG76271.1    
 SPS5912_08930   Staphylococcus pseudintermedius 5912 ASQ51079.1    
 SPSE_1829   Staphylococcus pseudintermedius ED99 ADX77079.1    
 SPSE_1611 (NanB)   Staphylococcus pseudintermedius ED99 ADX76869.1    
 D8L98_12070   Staphylococcus pseudintermedius G3C4 AYG57386.1    
 SPSINT_0694   Staphylococcus pseudintermedius HKU10-03 ADV05223.1    
 A9I66_08810   Staphylococcus pseudintermedius NA45 ANQ82112.1    
 GSP_17150   Staphylococcus pseudintermedius SP79 BBH74521.1    
 neuraminidase   Staphylococcus sciuri FDAARGOS_285 ASE35516.1    
 A7X73_12570   Staphylococcus simulans MR1 AWI02704.1    
 A9958_12680   Staphylococcus simulans MR2 AWG19756.1    
 BI282_12675   Staphylococcus simulans MR3 AVO03208.1    
 BI283_12690   Staphylococcus simulans MR4 AVO06163.1    
 SAMEA4384403_01390 (Nana_2)   Staphylococcus stepanovicii NCTC13839 SNV68384.1    
 Smon_0005   Streptobacillus moniliformis DSM 12112 ACZ00505.1 D1AW29  
 Smon_1211   Streptobacillus moniliformis DSM 12112 ACZ01666.1 D1AVA6  
 CEP89_04210   Streptobacillus moniliformis FDAARGOS_310 AVL43077.1    
 CEP89_05700   Streptobacillus moniliformis FDAARGOS_310 AVL43335.1    
 BQ8897_BM110_01966   Streptococcus agalactiae SIW58426.1    
 BSA_19490   Streptococcus agalactiae 09mas018883 CCW38715.1    
 SAG1932   Streptococcus agalactiae 2603V/R AAN00794.1
NP_688921.1
   
 DKY66_09940   Streptococcus agalactiae 32790-3A QDI66930.1    
 neuraminidase   Streptococcus agalactiae 874391 ASZ02150.1    
 SAK_1891 (partial)   Streptococcus agalactiae A909 ABA45464.1    
 CCZ24_00400   Streptococcus agalactiae B105 AWZ35352.1    
 CDH81_05630   Streptococcus agalactiae B111 AWZ34269.1    
 CDH84_08395   Streptococcus agalactiae B507 AWZ32765.1    
 CDH83_08855   Streptococcus agalactiae B508 AWZ30760.1    
 CDH85_04050   Streptococcus agalactiae B509 AWZ27847.1    
 GT95_09720   Streptococcus agalactiae C001 ASI66881.1    
 W903_1868   Streptococcus agalactiae CNCTC 10/84 AIX05533.1    
 GBSCOH1_1727   Streptococcus agalactiae COH1 CDN67193.1    
 BB161_10290   Streptococcus agalactiae CUGBS591 ASA80531.1    
 CUGBS08_01861 (Nana_2)   Streptococcus agalactiae CU_GBS_08 AMQ15409.1    
 CUGBS98_01797 (Nana_2)   Streptococcus agalactiae CU_GBS_98 AMQ17400.1    
 A6J82_03365   Streptococcus agalactiae FDAARGOS_254 ARC44456.1    
 EGX82_07260   Streptococcus agalactiae FDAARGOS_512 AYZ23620.1    
 A9256_09310   Streptococcus agalactiae FWL1402 ANR97840.1    
 AOY37_09505   Streptococcus agalactiae GBS ST-1 ALP88339.1    
 AV644_09270   Streptococcus agalactiae GBS-M002 APS25822.1    
 DK41_10055   Streptococcus agalactiae GBS1-NY AIK72457.1    
 DK42_10410   Streptococcus agalactiae GBS2-NM AIK74589.1    
 DX05_10030   Streptococcus agalactiae GBS6 AIK76564.1    
 GBS85147_1819   Streptococcus agalactiae GBS85147 AKI58240.1    
 A964_1791 (Neu1)   Streptococcus agalactiae GD201008-001 AFS46548.1    
 GX064_09090   Streptococcus agalactiae GX064 AKU00746.1    
 SAH002_09620   Streptococcus agalactiae H002 AKU04382.1    
 SAHN016_09170   Streptococcus agalactiae HN016 AKT96870.1    
 SAGS_1996 (Nana_2)   Streptococcus agalactiae HU-GS5823 BBG33677.1    
 MSA_20180   Streptococcus agalactiae ILRI005 CCW40873.1    
 SAIL_19510   Streptococcus agalactiae ILRI112 CCW42962.1    
 NCTC11930_00283 (Nana_2)   Streptococcus agalactiae NCTC11930 SQF30124.1    
 NCTC13947_00325 (Nana_1)   Streptococcus agalactiae NCTC13947 VEJ27040.1    
 NCTC13949_01869 (Nana_2)   Streptococcus agalactiae NCTC13949 VEJ13613.1    
 NCTC8184_00434 (Nana_1)   Streptococcus agalactiae NCTC8184 VED64464.1    
 NCTC8187_01868 (Nana_2)   Streptococcus agalactiae NCTC8187 SQG27151.1    
 Gbs1919   Streptococcus agalactiae NEM316 CAD47578.1
NP_736353.1
   
 EN72_10135   Streptococcus agalactiae NGBS061 AIF87430.1    
 AMM49_09330   Streptococcus agalactiae NGBS128 AMD33094.1    
 AMR84_09690   Streptococcus agalactiae NGBS357 AOF51826.1    
 EN73_09225   Streptococcus agalactiae NGBS572 AIF89367.1    
 DLM82_09790   Streptococcus agalactiae PLGBS13 QDK30916.1    
 DSN71_09450   Streptococcus agalactiae S73 AXC18157.1    
 SaSA375_1644 (fragment)   Streptococcus agalactiae SA375 AUP38884.1    
 SaSA375_1645 (fragment)   Streptococcus agalactiae SA375 AUP38885.1    
 SaSA623_1643 (fragment)   Streptococcus agalactiae SA623 AUP40620.1    
 SaSA623_1644 (fragment)   Streptococcus agalactiae SA623 AUP40621.1    
 SaSA627_1645 (fragment)   Streptococcus agalactiae SA627 AUP42348.1    
 SaSA627_1644 (fragment)   Streptococcus agalactiae SA627 AUP42347.1    
 B2G84_09740   Streptococcus agalactiae Sag158 AQY27133.1    
 DY328_02910   Streptococcus agalactiae Sag27 AXO11217.1    
 B1H24_10200   Streptococcus agalactiae Sag37 AQY25110.1    
 AMD29_09470   Streptococcus agalactiae SG-M1 ALB16795.1    
 BB194_09675   Streptococcus agalactiae SG-M158 ASA84642.1    
 BB197_09675   Streptococcus agalactiae SG-M163 ASA82588.1    
 BB164_10280   Streptococcus agalactiae SG-M25 ASA90889.1    
 BB268_09675   Streptococcus agalactiae SG-M29 ASA88743.1    
 BB165_09520   Streptococcus agalactiae SG-M4 ASA99746.1    
 BB313_09670   Streptococcus agalactiae SG-M50 ASA86689.1    
 BB162_09670   Streptococcus agalactiae SG-M6 ASA95066.1    
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