Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6503); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6269) Archaea (1) Bacteria (5793) Eukaryota (431) Viruses (37) unclassified (7) Structure (21) Characterized (97)
| 1 | ... | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | ... | 59 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 PH4a_06185   Proteus hauseri 15H5D-4a QAV22961.1    
 FU796_17750   Proteus mirabilis 1701092 QIF49953.1    
 AOUC001_00795   Proteus mirabilis AOUC-001 AND11465.1    
 CSC16_3584   Proteus mirabilis AR379 AWF40205.1    
 AM356_15420   Proteus mirabilis AR_0029 AWS56137.1    
 AM438_06795   Proteus mirabilis AR_0059 ARA22207.1    
 AM402_02945   Proteus mirabilis AR_0155 ARX33140.1    
 AM403_11785   Proteus mirabilis AR_0156 ASB02300.1    
 AM405_12345   Proteus mirabilis AR_0159 ARX09608.1    
 BB2000_2948   Proteus mirabilis BB2000 AGS61396.1    
 C3Z14_17530   Proteus mirabilis BC11-24 AVA41724.1    
 CLH65_10520   Proteus mirabilis CCUG 70746 AWR59767.1    
 GD587_06905   Proteus mirabilis CRE14IB QFV07007.1    
 FY167_17890   Proteus mirabilis CRPM10 QEK49781.1    
 AOC00_15890   Proteus mirabilis CYPM1 ALE23590.1    
 F4W58_18065   Proteus mirabilis ENT1157 QGM66916.1    
 F4W59_18055   Proteus mirabilis ENT1224 QGM73876.1    
 F4W60_16980   Proteus mirabilis ENT1301 QGM70283.1    
 MC46_018560   Proteus mirabilis FDAARGOS_60 AUT93610.1    
 MC53_010260   Proteus mirabilis FDAARGOS_67 AUU14371.1    
 MC72_016725   Proteus mirabilis FDAARGOS_80 AUU36934.1    
 MC73_000860   Proteus mirabilis FDAARGOS_81 AUU37578.1    
 PMI2938   Proteus mirabilis HI4320 CAR45786.1 B4EZP0  
 F3Y08_15045   Proteus mirabilis K817 QES79069.1    
 GYM49_16455   Proteus mirabilis N18-00201 QHZ90627.1    
 neuraminidase   Proteus mirabilis NCTC4199 VEB90721.1    
 EHQ66_17675   Proteus mirabilis PmBC1123 AZH00241.1    
 G9C79_05940   Proteus mirabilis PmBR607 QIJ52801.1    
 EHQ78_16765   Proteus mirabilis PmSC1111 AZH07226.1    
 EHZ20_13825   Proteus mirabilis S1959 QER01071.1    
 GO498_18495   Proteus mirabilis SCBX1.1 QHA72246.1    
 HF524_17935   Proteus mirabilis STP3 QJB74887.1    
 BG029_00410   Proteus mirabilis T18 ATC76995.1    
 BG257_06685   Proteus mirabilis T21 ATC74312.1    
 FVP19_18605   Proteus mirabilis VAC QEG47301.1    
 G9Q98_17600   Proteus mirabilis XH1568 QIM26502.1    
 G9R00_17515   Proteus mirabilis XH1569 QIM30026.1    
 GTH26_16960   Proteus mirabilis ZA25 QIG03294.1    
 BTA34_15980   Proteus sp. CD3 QEZ93752.1    
 GTK47_03185   Proteus sp. ZN5 QIG04401.1    
 AOB99_15925   Proteus vulgaris CYPV1 ALE26754.1    
 CRN77_04990   Proteus vulgaris FDAARGOS_366 ATM99107.1    
 EGX81_16265   Proteus vulgaris FDAARGOS_556 AYY82339.1    
 neuraminidase   Proteus vulgaris NCTC13145 VTP78538.1    
 EKQ45_20270   Proteus vulgaris PvSC3 QHP78133.1    
 GTH24_19015   Proteus vulgaris ZN3 QIF95859.1    
 GCE65_04130   Pseudactinotalea sp. HY158 QGH68774.1    
 GCE65_13215   Pseudactinotalea sp. HY158 QGH70343.1    
 GCE65_01795   Pseudactinotalea sp. HY158 QGH68382.1    
 GCE65_02115   Pseudactinotalea sp. HY158 QGH68434.1    
 neuraminidase   Pseudactinotalea sp. HY158 QGH68642.1    
 GCE65_03350   Pseudactinotalea sp. HY158 QGH68644.1    
 GCE65_03350   Pseudactinotalea sp. HY158 QGH68644.1    
 HME7025_00167   Pseudarcicella sp. HME7025 AWL08050.1    
 HME7025_00157   Pseudarcicella sp. HME7025 AWL08040.1    
 HME7025_01831 (Neu1)   Pseudarcicella sp. HME7025 AWL09682.1    
 Achl_1110   Pseudarthrobacter chlorophenolicus A6 ACL39102.1 B8HE67  
 Achl_3384   Pseudarthrobacter chlorophenolicus A6 ACL41341.1 B8HGS5  
 Achl_3385 (possible fragment)   Pseudarthrobacter chlorophenolicus A6 ACL41342.1 B8HGS6  
 SAMN04489743_3829   Pseudarthrobacter equi IMMIB L-1606 SDT59708.1    
 SAMN04489743_3828   Pseudarthrobacter equi IMMIB L-1606 SDT59691.1    
 neuraminidase   Pseudarthrobacter equi IMMIB L-1606 SDT00114.1    
 Asphe3_10870   Pseudarthrobacter phenanthrenivorans Sphe3 ADX72270.1    
 NIBR502770_15570   Pseudarthrobacter sp. NIBRBAC000502770 QDG89746.1    
 NIBR502771_07795   Pseudarthrobacter sp. NIBRBAC000502771 QDG62225.1    
 NIBR502771_07790   Pseudarthrobacter sp. NIBRBAC000502771 QDG62224.1    
 NIBR502772_03360   Pseudarthrobacter sp. NIBRBAC000502772 QDG65381.1    
 AU252_07450   Pseudarthrobacter sulfonivorans Ar51 ALV41009.1    
 AU252_09175   Pseudarthrobacter sulfonivorans Ar51 ALV41299.1    
 G6O69_16105   Pseudenhygromyxa sp. WMMC2535 QII80051.1    
 PSHAb0159   Pseudoalteromonas haloplanktis TAC125 CAI89205.1 Q3ID24  
 PTRA_b0222   Pseudoalteromonas translucida KMM 520 ALS34740.1    
 FSB84_27470   Pseudobacter ginsenosidimutans Gsoil 221 QEC45249.1    
 FSB84_27475   Pseudobacter ginsenosidimutans Gsoil 221 QEC45250.1    
 neuraminidase   Pseudoclostridium thermosuccinogenes DSM 5807 AUS95056.1    
 CDO33_07960   Pseudoclostridium thermosuccinogenes DSM 5807 AUS96375.1    
 G5B38_15590 (fragment)   Pseudohalocynthiibacter aestuariivivens RR4-35 QIE46829.1    
 CSC28_2469   Pseudomonas aeruginosa AR441 AWE90993.1    
 CSB93_3686 (fragment)   Pseudomonas aeruginosa AR_0356 AVK04142.1    
 NCTC13718_00943 (NedA)   Pseudomonas aeruginosa NCTC13718 SQG57602.1    
 UYA_00555   Pseudomonas alcaliphila JAB1 APU28273.1    
 B5U27_19605   Pseudomonas amygdali pv. lachrymans NM002 ARA82101.1    
 B5U27_10180   Pseudomonas amygdali pv. lachrymans NM002 ARA80402.1    
 PLA107_019575   Pseudomonas amygdali pv. lachrymans str. M301315 AXH57252.1    
 PLA107_011310   Pseudomonas amygdali pv. lachrymans str. M301315 AXH55833.1    
 BKM19_020580   Pseudomonas amygdali pv. morsprunorum R15244 AVB15706.1    
 BKM19_020535   Pseudomonas amygdali pv. morsprunorum R15244 AVB15697.1    
 PSYTB_18775   Pseudomonas amygdali pv. tabaci str. ATCC 11528 QED85570.1    
 PSYTB_18830   Pseudomonas amygdali pv. tabaci str. ATCC 11528 QED85581.1    
 A7J50_4862   Pseudomonas antarctica PAMC 27494 ANF88206.1    
 neuraminidase   Pseudomonas asplenii ATCC 23835 SDT30534.1    
 N015_18340   Pseudomonas asturiensis CC1524 QHF04261.1    
 BKM03_20100   Pseudomonas avellanae R2leaf AVB21274.1    
 neuraminidase   Pseudomonas azotoformans LMG 21611 SDN95636.1    
 FKZ69_27090   Pseudomonas azotoformans P45A QDH67506.1    
 AYR47_01420   Pseudomonas azotoformans S4 AMN77063.1    
 PCPL58_1787   Pseudomonas cerasi CZT28243.1    
 PCPL58_1777   Pseudomonas cerasi CZT28233.1    
 PL963_01818   Pseudomonas cerasi SOS18312.1    
 PL963_01828   Pseudomonas cerasi SOS18333.1    
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