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Glycoside Hydrolase Family 33

Activities in FamilyTrans-sialidase (EC 2.4.1.-);
2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-);
Kdo hydrolase (EC 3.2.1.124);
Exo-α-sialidase (EC 3.2.1.18);
Anhydrosialidase (EC 4.2.2.15);
Mechanism Retaining e
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (11064); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0)
Summary
Download GH33 (11058) Taxonomic display Structure (29) Characterized (97)
| 1 | ... | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | ... | 104 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 exo-α-sialidase (NanJ;CPE0553)   Clostridium perfringens str. 13 BAB80259.1
NP_561469.1		    
 exo-α-sialidase (NanI;CPSA;CPE0725) 3.2.1.18 Clostridium perfringens str. 13 BAB80431.1
NP_561641.1		 Q59310
Q8XMG4		 2BF6[A]
2VK5[A]
2VK6[A]
2VK7[A,B]
 neuraminidase   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF57738.1    
 CP523_01750   Clostridium septicum DSM 7534 AYE33273.1    
 sialidase 3.2.1.18 Clostridium septicum NC0054714 CAA44916.1 P29767  
 NH397_10070   Clostridium septicum RMA 8861 USR99847.1    
 EI377_12270   Clostridium septicum VAT12 QAS61444.1    
 Q6375_10245   Clostridium septicum WW106 WLF68367.1    
 GOM42_02925   Clostridium sp. 16K-1-R1 USQ64039.1    
 GOM42_04900   Clostridium sp. 16K-1-R1 USQ64412.1    
 GOM42_03895   Clostridium sp. 16K-1-R1 USQ64221.1    
 neuraminidase   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET85419.1    
 sialidase (NanH;SiaH) 3.2.1.18 Clostridium tertium CAA69951.1 P77848  
 neuraminidase   Cohaesibacter sp. ES.047 SNY92957.1    
 EAV92_22715   Cohnella sp. 18JY8-7 AYQ75794.1    
 KPC83_06470   Collinsella sp. zg1085 QWT17473.1    
 os4_29190   Comamonadaceae bacterium OS-4 BDT73370.1    
 NF681_02595   Comamonadaceae bacterium OTU4NAUVB1 UST52826.1    
 NOX35_19045   Comamonas sp. C11 UUC92363.1    
 SR914_14670   Comamonas testosteroni DSMZ 14576 WQG64474.1    
 O987_20575   Comamonas testosteroni TK102 AIJ48208.1    
 LZ683_19910   Comamonas testosteroni X13 WEE76391.1    
 Cfast33896_21620 (fragment)   Coprobacter fastidiosus JCM 33896 BEG63207.1    
 Cop2CBH44_23460   Coprobacter secundus subsp. similis 2CBH44 BCI63993.1    
 Cop2CBH44_24650   Coprobacter secundus subsp. similis 2CBH44 BCI64112.1    
 CC1_03920   Coprococcus catus GD/7 CBK79325.1    
 SH580_03335   Coraliomargarita sp. J2-16 WPJ96737.1    
 CAQUA_06310 (NedA)   Corynebacterium aquatimens DSM 45632 WJY65967.1    
 CAQU_07700   Corynebacterium aquilae DSM 44791 S-613 APT84974.1    
 CAQU_01300   Corynebacterium aquilae DSM 44791 S-613 APT83930.1    
 CATRI_12955 (NanA)   Corynebacterium atrinae JCM 19266 WJY64636.1    
 H924_11155   Corynebacterium callunae DSM 20147 AGG67659.1    
 CCANI_13545 (NedA) (fragment)   Corynebacterium canis DSM 45402 WJY76508.1    
 CCASEI_03525   Corynebacterium casei LMG S-19264 AHI19285.1    
 CCHOA_05190 (NanA)   Corynebacterium choanae 200CH AZA13443.1    
 SCMU_33940   Corynebacterium cyclohexanicum ATCC 51369 BCT77552.1    
 SCMU_05430   Corynebacterium cyclohexanicum ATCC 51369 BCT74701.1    
 CDES_12030   Corynebacterium deserti GIMN1.010 ALC06756.1    
 NCTC11397BIS_00474   Corynebacterium diphtheriae CAB1042623.1    
 NCTC11397BIS_00258   Corynebacterium diphtheriae CAB1040495.1    
 CD241_0285   Corynebacterium diphtheriae 241 AEX43353.1    
 CD241_0480 (NanH)   Corynebacterium diphtheriae 241 AEX43547.1    
 CD31A_0333   Corynebacterium diphtheriae 31A AEX41018.1    
 CD31A_0540 (NanH)   Corynebacterium diphtheriae 31A AEX41224.1    
 BS112_10690   Corynebacterium diphtheriae B-D-16-78 APM36886.1    
 BS112_09660   Corynebacterium diphtheriae B-D-16-78 APM36707.1    
 CDBH8_0495 (NanH)   Corynebacterium diphtheriae BH8 AEX48020.1    
 CDBH8_0280   Corynebacterium diphtheriae BH8 AEX47805.1    
 B11Q_00514 (NanH)   Corynebacterium diphtheriae BQ11 AWR15220.1    
 NY045_07290   Corynebacterium diphtheriae bv. gravis 1269/21 UWE72648.1    
 NY042_02360   Corynebacterium diphtheriae bv. gravis 14225/20 UWF07528.1    
 NY042_01330   Corynebacterium diphtheriae bv. gravis 14225/20 UWF07348.1    
 NY046_08690   Corynebacterium diphtheriae bv. gravis 1784/21 UWF12305.1    
 NY047_03150   Corynebacterium diphtheriae bv. gravis 2232/21 UWF03876.1    
 NY033_02060   Corynebacterium diphtheriae bv. gravis 2736/18 UWE80005.1    
 NY033_01030   Corynebacterium diphtheriae bv. gravis 2736/18 UWE79823.1    
 NY056_03605   Corynebacterium diphtheriae bv. gravis 3302/22 UWE70367.1    
 NY048_01125   Corynebacterium diphtheriae bv. gravis 3745/21 UWE86165.1    
 NY048_02170   Corynebacterium diphtheriae bv. gravis 3745/21 UWE86338.1    
 NY031_11010   Corynebacterium diphtheriae bv. gravis 453/18 UWE94171.1    
 NY031_00525   Corynebacterium diphtheriae bv. gravis 453/18 UWE94354.1    
 NY034_02365   Corynebacterium diphtheriae bv. gravis 4674/18 UWF24751.1    
 NY034_01330   Corynebacterium diphtheriae bv. gravis 4674/18 UWF24567.1    
 NY049_03840   Corynebacterium diphtheriae bv. gravis 4795/21 UWF09867.1    
 NY041_01030   Corynebacterium diphtheriae bv. gravis 49390/20 UWE82005.1    
 NY041_02065   Corynebacterium diphtheriae bv. gravis 49390/20 UWE82189.1    
 NY037_00525   Corynebacterium diphtheriae bv. gravis 5379/19 UWF20041.1    
 NY037_10970   Corynebacterium diphtheriae bv. gravis 5379/19 UWF19858.1    
 NY029_02360   Corynebacterium diphtheriae bv. gravis 5521/17 UWF18161.1    
 NY029_01325   Corynebacterium diphtheriae bv. gravis 5521/17 UWF17977.1    
 NY043_04195   Corynebacterium diphtheriae bv. gravis 576/21 UWE76040.1    
 NY032_10870   Corynebacterium diphtheriae bv. gravis 5790/18 UWE77369.1    
 NY032_00530   Corynebacterium diphtheriae bv. gravis 5790/18 UWE77556.1    
 NY027_00525   Corynebacterium diphtheriae bv. gravis 6211/17 UWF28853.1    
 NY027_10955   Corynebacterium diphtheriae bv. gravis 6211/17 UWF28669.1    
 NY051_07870   Corynebacterium diphtheriae bv. gravis 648/22 UWE91116.1    
 NY030_02060   Corynebacterium diphtheriae bv. gravis 7072/17 UWF15970.1    
 NY030_01030   Corynebacterium diphtheriae bv. gravis 7072/17 UWF15789.1    
 NY038_02060   Corynebacterium diphtheriae bv. gravis 8259/19 UWF05346.1    
 NY038_01030   Corynebacterium diphtheriae bv. gravis 8259/19 UWF05164.1    
 NY052_09820   Corynebacterium diphtheriae bv. mitis 1251/22 UWF00564.1    
 NY054_08795 (fragment)   Corynebacterium diphtheriae bv. mitis 2102/22 UWE87515.1    
 NY054_08800 (fragment)   Corynebacterium diphtheriae bv. mitis 2102/22 UWE87516.1    
 NY035_04220   Corynebacterium diphtheriae bv. mitis 230/19 UWF22874.1    
 NY035_03190   Corynebacterium diphtheriae bv. mitis 230/19 UWF22691.1    
 NY055_03035   Corynebacterium diphtheriae bv. mitis 2633/22 UWE72282.1    
 NY040_03185   Corynebacterium diphtheriae bv. mitis 38009/20 UWE99214.1    
 NY040_04215   Corynebacterium diphtheriae bv. mitis 38009/20 UWE99398.1    
 NY028_03195   Corynebacterium diphtheriae bv. mitis 6272/17 UWF14467.1    
 NY028_04225   Corynebacterium diphtheriae bv. mitis 6272/17 UWF14102.1    
 NY036_04220   Corynebacterium diphtheriae bv. mitis 632/19 UWF27280.1    
 NY036_03190   Corynebacterium diphtheriae bv. mitis 632/19 UWF27097.1    
 NY044_03695   Corynebacterium diphtheriae bv. mitis 641/21 UWE93145.1    
 NY039_02445   Corynebacterium diphtheriae bv. mitis 824/20 UWE97537.1    
 NY039_01415   Corynebacterium diphtheriae bv. mitis 824/20 UWE96671.1    
 FGA20_02390   Corynebacterium diphtheriae bv. mitis PC0646 QOE67340.1    
 FGA20_01350   Corynebacterium diphtheriae bv. mitis PC0646 QOE67157.1    
 CDC7B_0498 (NanH)   Corynebacterium diphtheriae C7 (beta) AEX66697.1    
 CDC7B_0282   Corynebacterium diphtheriae C7 (beta) AEX66482.1    
 FE375_01690   Corynebacterium diphtheriae CD1005 UJL61906.1    
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