Glycoside Hydrolase Family 30

Known Activitiesglucosylceramidase (EC 3.2.1.45); b-1,6-glucanase (EC 3.2.1.75); b-xylosidase (EC 3.2.1.37); b-fucosidase (EC 3.2.1.38); b-glucosidase (3.2.1.21); endo-b-1,6-galactanase (EC:3.2.1.164)
Mechanism Retaining
ClanGH-A
3D Structure Status(b/a)8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; InterPro; PFAM; PRINTS;
Statistics GenBank accession (548); Uniprot accession (247); PDB accession (31); 3D entries (6); cryst (1)
All (441) Bacteria (384) Eukaryota (55) unclassified (2) Structure (6 - 1 cryst) Characterized (26) Subfamilies (395)
unclassified
Protein Name EC#OrganismGenBankUniprotPDB/3D Subf
 Sequence 236 from patent US 7504120.   unidentified ACP87394.1
ACW02022.1
    8
 Sequence 314 from patent US 7504120.   unidentified ACP87433.1
ACW02061.1
    7




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