Glycoside Hydrolase Family 30

Activities in Familyendo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (3.2.1.21); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-fucosidase (EC 3.2.1.38); glucosylceramidase (EC 3.2.1.45); β-1,6-glucanase (EC 3.2.1.75); glucuronoarabinoxylan endo-β-1,4-xylanase (EC 3.2.1.136); endo-β-1,6-galactanase (EC:3.2.1.164); [reducing end] β-xylosidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (1753); Uniprot accession (263); PDB accession (45); 3D entries (11); cryst (1)
All (1619) Bacteria (1530) Eukaryota (87) unclassified (2) Structure (11 - 1 cryst) Characterized (38)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 16 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 FORMA_09910   Formosa sp. Hel3_A1_48 AOR26160.1     3
 FRAAL0799   Frankia alni ACN14a CAJ59468.1 Q0RSJ4   3
 FRAAL6101   Frankia alni ACN14a CAJ64725.1 Q0RCU9   3
 GEMMAAP_01490   Gemmatimonas phototrophica AP64 AMW06463.1     3
 Gobs_1516   Geodermatophilus obscurus DSM 43160 ADB74242.1 D2SC74   3
 AWC35_19250   Gibbsiella quercinecans FRB97 ATA21302.1     1
 GRFL_0925   Gramella flava JLT2011 APU67649.1     3
 GRFL_2254   Gramella flava JLT2011 APU68978.1     4
 SAMN04488552_1343   Gramella sp. MAR_2010_102 SDR87193.1     3
 AciX8_4163   Granulicella mallensis MP5ACTX8 AEU38443.1     3
 AciX9_3990   Granulicella tundricola MP5ACTX9 ADW71264.1     3
 glucuronoxylanase (YC6258_04184)   Gynuella sunshinyii YC6258 AHM95442.1
AJQ96218.1
    8
 Hoch_6250   Haliangium ochraceum DSM 14365 ACY18721.1 D0LMN4   3
 BST95_07835   Halioglobus japonicus NBRC 107739 AQA20202.1    
 Halhy_1114   Haliscomenobacter hydrossis DSM 1100 AEE49012.1     1
 Halhy_1362   Haliscomenobacter hydrossis DSM 1100 AEE49257.1     3
 HBHAL_1426   Halobacillus halophilus DSM 2266 CCG43797.1     1
 HBHAL_4388 (SrfJ)   Halobacillus halophilus DSM 2266 CCG46728.1     1
 CEH05_16695   Halobacillus halophilus HL2HP6 ASF40702.1     1
 CEH05_02300   Halobacillus halophilus HL2HP6 ASF37999.1     1
 Halha_0266   Halobacteroides halobius DSM 5150 AGB40277.1     1
 BOX17_08890   Halomonas aestuarii Hb3 APE31056.1     1
 Hore_04190   Halothermothrix orenii H 168 ACL69177.1 B8D1V0   1
 AUC43_17120   Hymenobacter sedentarius DG5B ALW86648.1     1
 N008_01825   Hymenobacter sp. APR13 AII50721.1     3
 N008_01835   Hymenobacter sp. APR13 AII50723.1     3
 N008_01840   Hymenobacter sp. APR13 AII50724.1     1
 AM218_09000   Hymenobacter sp. DG25A ALD21329.1     3
 AM218_09005   Hymenobacter sp. DG25A ALD22692.1     1
 PK28_07220   Hymenobacter sp. DG25B AIZ65080.1     1
 A0257_18045   Hymenobacter sp. PAMC 26554 AMR28809.1     4
 A0257_09340   Hymenobacter sp. PAMC 26554 AMR27282.1     1
 A0257_09330   Hymenobacter sp. PAMC 26554 AMR27280.1     3
 A0257_09335   Hymenobacter sp. PAMC 26554 AMR27281.1     3
 AXW84_20235 (fragment)   Hymenobacter sp. PAMC 26628 AMJ67488.1    
 AXW84_01680   Hymenobacter sp. PAMC 26628 AMJ67967.1     3
 AXW84_13085   Hymenobacter sp. PAMC 26628 AMJ66266.1     1
 AXW84_08780   Hymenobacter sp. PAMC 26628 AMJ68094.1     2
 Hsw_1827   Hymenobacter swuensis DY53 AHJ97422.1     1
 Hsw_1828   Hymenobacter swuensis DY53 AHJ97423.1     3
 Hsw_1832   Hymenobacter swuensis DY53 AHJ97427.1     3
 I598_3442   Isoptericola dokdonensis DS-3 ANC32950.1     5
 SAMN04515669_2187   Jiangella sp. DSM 45060 SDS88534.1    
 AOZ06_17340   Kibdelosporangium phytohabitans KLBMP1111 ALG08444.1     3
 ORF   Kibdelosporangium sp. MJ126-NF4 CTQ97110.1     5
 B7C62_00265   Kitasatospora albolonga YIM 101047 ARF70850.1     3
 B6264_03180   Kitasatospora aureofaciens DM-1 ARF78052.1     5
 KSE_67260   Kitasatospora setae KM-6054 BAJ32484.1 E4N2V0   3
 Kfla_7049   Kribbella flavida DSM 17836 ADB36037.1 D2Q526   3
 Kfla_5264   Kribbella flavida DSM 17836 ADB34278.1 D2PL23   3
 KALB_2205   Kutzneria albida DSM 43870 AHH95574.1     3
 KALB_2434   Kutzneria albida DSM 43870 AHH95802.1    
 Cphy_0858   Lachnoclostridium phytofermentans ISDg ABX41244.1 A9KLB5   1
 Cphy_3404   Lachnoclostridium phytofermentans ISDg ABX43757.1 A9KTC7   1
 A6F60_03730   Lactobacillus brevis 100D8 ARQ92860.1    
 A6F60_05325   Lactobacillus brevis 100D8 ARQ93153.1     2
 LVIS_2226 (LcGUS30)   Lactobacillus brevis ATCC 367 ABJ65276.1 Q03NE6  
 L747_12945   Lactobacillus brevis BSO 464 AJA80589.1    
 LVISKB_2298 (LcGUS30)   Lactobacillus brevis KB290 BAN07933.1    
 LVISKB_0246   Lactobacillus brevis KB290 BAN05881.1     2
 A6F53_00780   Lactobacillus brevis NPS-QW-145 ANN47870.1    
 A6F53_02580   Lactobacillus brevis NPS-QW-145 ANN48190.1     2
 S101174_02419 (SrfJ)   Lactobacillus brevis SRCM101174 ARW23224.1    
 β-glucuronidase (LcGUS30) 3.2.1.31 Lactobacillus brevis subsp. coagulans FERM BP-4693 BAO73305.1    
 AZI11_12260   Lactobacillus brevis TMW 1.2108 ARN93610.1    
 AZI12_12290   Lactobacillus brevis TMW 1.2111 ARN96192.1    
 AZI09_00755   Lactobacillus brevis TMW 1.2112 ARN89199.1    
 AZI10_00750   Lactobacillus brevis TMW 1.2113 ARN96782.1    
 LBUCD034_0428   Lactobacillus buchneri CD034 AFR99527.1     2
 Lbuc_0391   Lactobacillus buchneri NRRL B-30929 AEB72663.1     2
 BGL52_00215   Lactobacillus casei LC5 ARY90263.1    
 LOOC260_120960   Lactobacillus hokkaidonensis JCM 18461 BAP86602.1    
 ABN16_04035   Lactobacillus koreensis 26-25 AKP64244.1     2
 A0F16_12750   Lactobacillus rhamnosus ASCC 290 AMQ04274.1    
 LRHK_53   Lactobacillus rhamnosus ATCC 8530 AER62912.1    
 LC705_00049   Lactobacillus rhamnosus Lc 705 CAR88888.1 C7TFA4  
 LOCK900_0053   Lactobacillus rhamnosus LOCK900 AGP69913.1    
 LOCK908_0052   Lactobacillus rhamnosus LOCK908 AGP72739.1    
 BGK71_00235   Lactobacillus rhamnosus LR5 ASX15918.1    
 BVH57_00555   Lactobacillus rhamnosus Pen ARD31009.1    
 LZ3411_0284   Lactobacillus zymae ACA-DC 3411 SMS13334.1    
 Lbys_0833   Leadbetterella byssophila DSM 17132 ADQ16581.1 E4RQL5   4
 SAMN04515680_3041   Leifsonia sp. 21MFCrub1.1 SEB07469.1    
 BBK82_35940 (fragment)   Lentzea guizhouensis DHS C013 ANZ40597.1     5
 BBK82_30440   Lentzea guizhouensis DHS C013 ANZ43149.1     5
 BBK82_39035   Lentzea guizhouensis DHS C013 ANZ41092.1     3
 BBK82_39030   Lentzea guizhouensis DHS C013 ANZ41091.1     3
 BBK82_39515   Lentzea guizhouensis DHS C013 ANZ41165.1     5
 BJI69_06150   Luteibacter rhizovicinus LJ96T APG06384.1     3
 VV02_13560   Luteipulveratus mongoliensis MN07-A0370 AKU16655.1     3
 Mahau_1803   Mahella australiensis 50-1 BON AEE96984.1    
 BTR34_08075   Maribacter sp. T28 APQ17286.1     3
 ALGA_2732   Marinifilaceae bacterium SPP2 BAX81044.1     1
 ALGA_4300   Marinifilaceae bacterium SPP2 BAX82590.1     1
 ALGA_4294   Marinifilaceae bacterium SPP2 BAX82584.1     1
 ALGA_3446   Marinifilaceae bacterium SPP2 BAX81744.1     2
 ALGA_2498   Marinifilaceae bacterium SPP2 BAX80820.1     2
 AM586_18495   Massilia sp. WG5 ALK99704.1     3
 AM586_18485   Massilia sp. WG5 ALK99703.1     1
 MROS_0117   Melioribacter roseus P3M-2 AFN73361.1     1
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