Glycoside Hydrolase Family 30 / Subf 8

Activities in Familyendo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (3.2.1.21); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-fucosidase (EC 3.2.1.38); glucosylceramidase (EC 3.2.1.45); β-1,6-glucanase (EC 3.2.1.75); glucuronoarabinoxylan endo-β-1,4-xylanase (EC 3.2.1.136); endo-β-1,6-galactanase (EC:3.2.1.164); [reducing end] β-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (395); Uniprot accession (50); PDB accession (18); 3D entries (6); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 xylanase VI / D (XynD) 3.2.1.8 Aeromonas caviae ME-1 AAB63573.1 O24852   8
 glucuronoarabinoxylan-specific endo-β-1,4-xylanase (XynC) (Xyn30A) 3.2.1.136
3.2.1.8
Bacillus licheniformis SVD1 BAL45490.1     8
 xylanase 5B (Xyn5B) 3.2.1.8 Bacillus sp. BP7 ADM15019.1 E1ACF9   8
 glucuronoxylan xylanohydrolase (feraxanase) / xylanase C (XynC;YnfF;BSU18150) 3.2.1.136
3.2.1.8
Bacillus subtilis subsp. subtilis str. 168 CAA97612.1
AIY93125.1
AQR81806.1
AQR86020.1
CAB13698.1
NP_389697.1
Q45070 3GTN[A,B]
3KL0[A,B,C,D]
3KL3[A,B,C,D]
3KL5[A,B,C,D]
8
 glucuronoxylanase (BoGH30;BACOVA_03432) 3.2.1.136 Bacteroides ovatus ATCC 8483 ZP_02066435.1 A7M005   8
 CGSCsYakCAS_04919 (Xyn30A) 3.2.1.8 Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98597.1 D2KFJ5   8
 xylanase (CAP0119) (Xyn30A) 3.2.1.8 Clostridium acetobutylicum ATCC 824 AAK76864.1
NP_149282.1
Q97TI2 5CXP[A] 8
 endo-β-1,4-xylanase (C7I;CpC7I;CpXyn30A;Cpap_2855) (Xyn30A) 3.2.1.8 Clostridium papyrosolvens DSM 2782 EGD48159.1   4FMV[A] 8
 glucuronoxylanase / glucuronoxylan-specific endo-β-1,4-xylanase (XynA) 3.2.1.136
3.2.1.8
Dickeya chrysanthemi D1 AAB53151.1 Q46961 1NOF[A]
2Y24[A]
8
 endo-β-1,4-xylanase (XynA) 3.2.1.8 Dickeya chrysanthemi P860219 AAL16415.1 Q938A4   8
 xylanase (Xyl2090;MROS_2090) 3.2.1.8 Melioribacter roseus P3M-2 AFN75320.1     8
 glucuronoxylan-specific xylanase (Xyn30D) 3.2.1.136 Paenibacillus barcinonensis BP-23 AEY82463.1   4QAW[A,B,C,D,E,F,G,H] 8
 glucuronoxylan-specific xylanase (Xyn30A) 3.2.1.8 Paenibacillus favisporus CC02-N2 AHA38215.1     8
 xylanase 3 (Xyn3) 3.2.1.8 Paenibacillus sp. W-61 BAA13641.1 P70733   8
 xylanase (GH30A-CE;RUM_18530) (Xyn30A) 3.2.1.8 Ruminococcus champanellensis 18P13 = JCM 17042 CBL17903.1 D4LE58   8
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 xylanase (Mi-Xyl1;Xyl-1) 3.2.1.8 Meloidogyne incognita AAF37276.1 Q9NHE0   8
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