Glycoside Hydrolase Family 30 / Subf 7

Activities in Sub Familyxylanase cleaving 4-Me-GlcA or GlcA-substituted xylan (EC 3.2.1.-);[reducing end] b-xylosidase (EC 3.2.1.-);non-reducing end-specific xylobiohydrolase (EC 3.2.1.-);xylan b-1,4-xylosidase (EC 3.2.1.37);endo-b-1,4-xylanase (EC 3.2.1.8)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (104); Uniprot accession (6); PDB accession (7); 3D entries (4); cryst (1)
Eukaryota
Protein Name EC# OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
Subf
 bifunctional endo-glucuronoxylanase and exo-xylobiohydrolase (TcXyn30B) 3.2.1.8 Talaromyces cellulolyticus CF-2612   A0A4V8H018
A0A510NXC4
6IUJ[B] 2.25
6KRL[A] 1.60
6KRN[A] α-D-GlcpA4Me-(1-2)-β-D-Xylp-(1-4)-β-D-Xylp
1.65
6IUJ[A] 2.25
7
 TCE0_039f12750 3.2.1.8 Talaromyces cellulolyticus Y-94 GAM40414.1 A0A6N4SL16
6M5Z[A] 1.65
7
 endo-β-1,4-xylanase (TtXyn30A; MYCTH_38558) 3.2.1.8
3.2.1.-
Thermothelomyces thermophilus ATCC 42464 AEO55025.1
G2Q1N4.1
 
7NCX[A]
7O0E[A] α-D-GlcpA4Me-(1-2)-β-D-Xylp-(1-4)-β-D-Xylp
1.85
7
 exo-xylanase IV (Xyn4;XYN IV) 3.2.1.- Trichoderma reesei Rut C30 AAP64786.1
AAV25955.1
 
cryst    
7
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