| Activities in Family | endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (3.2.1.21); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-fucosidase (EC 3.2.1.38); glucosylceramidase (EC 3.2.1.45); β-1,6-glucanase (EC 3.2.1.75); glucuronoarabinoxylan endo-β-1,4-xylanase (EC 3.2.1.136); endo-β-1,6-galactanase (EC:3.2.1.164); [reducing end] β-xylosidase (EC 3.2.1.-) |
|---|---|
| Activities in Sub Family | |
| Mechanism | Retaining |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (inferred) |
| Note | Following St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated. |
| External resources | CAZypedia; Gaucher Disease; PRINTS; |
| Statistics | GenBank accession (381); Uniprot accession (64); PDB accession (2); 3D entries (1); cryst (0) |
| Bacteria | ||||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf | ||
| endo-β-1,6-glucanase (BT3312;BT_3312) | 3.2.1.75 | Bacteroides thetaiotaomicron VPI-5482 | AAO78418.1 NP_812224.1 |
Q8A2J3 | 5NGK[A,B,C] 5NGL[A,B,C] |
3 | ||
| endo-β-1,6-glucanase 30B (Sde_2994) (Gly30B) | 3.2.1.75 | Saccharophagus degradans 2-40 | ABD82251.1 | Q21GC8 | 3 | |||
| Eukaryota | ||||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf | ||
| β-1,6-glucanase (Neg1;Afu8g07120;AFUA_8G07120) | 3.2.1.75 | Aspergillus fumigatus Af293 | EAL85472.1 XP_747510.1 |
3 | ||||
| glucan endo-β-1,6-glucosidase (LePus30A) (Pus30A) | 3.2.1.75 | Lentinula edodes H600 | BAK52530.1 | 3 | ||||
| β-1,6-glucanase (Neg1;Neg-1) | 3.2.1.75 | Neurospora crassa IFO6068 | BAB91213.1 | Q7M4T0 | 3 | |||
| β-1,6-glucanase (Neg1;NCU04395.1/29E8.200) | 3.2.1.75 | Neurospora crassa OR74A | CAF06053.1 XP_323748.1 |
Q7M4T0 | 3 | |||
| β-1,6-glucanase (Bgn16.3;P2) | 3.2.1.75 | Trichoderma harzianum | CAC80492.1 ACM42429.1 |
Q8J0I9 | 3 | |||
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