Glycoside Hydrolase Family 30 / Subf 3

Activities in Familyendo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (3.2.1.21); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-fucosidase (EC 3.2.1.38); glucosylceramidase (EC 3.2.1.45); β-1,6-glucanase (EC 3.2.1.75); glucuronoarabinoxylan endo-β-1,4-xylanase (EC 3.2.1.136); endo-β-1,6-galactanase (EC:3.2.1.164); [reducing end] β-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (420); Uniprot accession (64); PDB accession (2); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 endo-β-1,6-glucanase (BT3312;BT_3312) 3.2.1.75 Bacteroides thetaiotaomicron VPI-5482 AAO78418.1
NP_812224.1
Q8A2J3 5NGK[A,B,C]
5NGL[A,B,C]
3
 endo-β-1,6-glucanase 30B (Sde_2994) (Gly30B) 3.2.1.75 Saccharophagus degradans 2-40 ABD82251.1 Q21GC8   3
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 β-1,6-glucanase (Neg1;Afu8g07120;AFUA_8G07120) 3.2.1.75 Aspergillus fumigatus Af293 EAL85472.1
XP_747510.1
    3
 glucan endo-β-1,6-glucosidase (LePus30A) (Pus30A) 3.2.1.75 Lentinula edodes H600 BAK52530.1     3
 β-1,6-glucanase (Neg1;Neg-1) 3.2.1.75 Neurospora crassa IFO6068 BAB91213.1 Q7M4T0   3
 β-1,6-glucanase (Neg1;NCU04395.1/29E8.200) 3.2.1.75 Neurospora crassa OR74A CAF06053.1
XP_323748.1
Q7M4T0   3
 β-1,6-glucanase (Bgn16.3;P2) 3.2.1.75 Trichoderma harzianum CAC80492.1
ACM42429.1
Q8J0I9   3
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