Activities in Sub Family	β-1,6-glucosidase (EC 3.2.1.-); β-glucosidase (EC 3.2.1.21); β-glucosylceramidase (EC 3.2.1.45);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (inferred)
Note	Following St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resources	CAZypedia; Gaucher Disease; PRINTS;
Statistics	GenBank accession (44); Uniprot accession (16); PDB accession (48); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
STM4426 (SrfJ)		Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	AAL23246.1 NP_463287.1		2WNW[A,B] 2.00	1
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
acid β-glucosidase 1 / β-glucocerebrosidase 1 (Gba1;Gba;GC;GCase;LOC82008) (lysosomal)	3.2.1.45	Homo sapiens	AAA35880.1 AAA35873.1 AAA35877.1 AAC51820.1 AAC63056.1 AAH03356.1 AAQ41981.1 AAQ41982.1 AAT13636.1 AAT13637.1 AAV20581.1 AAY03281.1 AAY03324.1 ABL21565.1 ACH14936.1 ACJ92748.1 ACM85831.1 ACM97663.1 AID60277.1 AID60278.1 AID60279.1 AID60280.1 ASU47376.1 BAA02545.1 BAF84600.1 BAG58248.1 BAG60020.1 BAH12898.1 BAH13232.1 BAH13357.1 BAH13365.1 BAH13467.1 BAH13605.1 CAC41172.1 CAC41173.1 CAD12720.1 CAD12721.1 CAE85438.1 CAI95090.1 NP_000148.1 SJX47168.1	A0A068F579 A0A068F658 A0A068F753 A0A068FB60 A0A223PQI4 B2R6A7 B4DHT6 B4DMV8 B7Z6E6 B7Z6S9 B7Z731 B7Z7G9 P04062	1OGS[A,B] 2.0 1Y7V[A,B] <carb_like_INS> 2.40 2F61[A,B] 2.50 2J25[A,B] 2.9 2NSX[A,B,C,D] <carb_like_IFM> 2.11 2NT0[A,B,C,D] D-1-deoxy-GlcpNAc 1.79 2NT1[A,B,C,D] 2.30 2V3D[A,B] <carb_like_NBV> 1.96 2V3E[A,B] <carb_like_NND> 2.00 2V3F[A,B] 1.95 2VT0[A,B] <carb_like_CBU> 2.15 2WCG[A,B] <carb_like_MT5> 2.30 2WKL[A,B] 2.70 2XWD[A,B] <carb_like_LGS> 2.66 2XWE[A,B] <carb_like_AMF> 2.31 3GXD[A,B,C,D] 2.50 3GXF[A,B,C,D] <carb_like_IFM> 2.40 3GXI[A,B,C,D] 1.84 3GXM[A,B,C,D] 2.20 3KE0[A,B] 2.70 3KEH[A,B] 2.80 3RIK[A,B,C,D] <carb_like_3RI> 2.48 3RIL[A,B,C,D] <carb_like_3RK> 2.40 5LVX[A,B,C,D] 2.20 6MOZ[A,B] 2.10 6Q1N[A,B] 2.53 6Q1P[A,B] 2.80 6Q6K[A,B] 1.92 6Q6L[A,B] 1.81 6Q6N[A,B] 1.63 6T13[A,B,C,D] 1.85 6TJJ[AAA,BBB] 6TJK[AAA,BBB] 6TJQ[BBB] 6TN1[AAA] 6YTP[A] 6YTR[A] 6YUT[A] 6YV3[A] 6Z39[A] 6Z3I[A] 7NWV[A,B] 8AWK[A] 8AWR[A] 8AX3[A,B] 8P3E[A,B] 8P41[A,B]	1
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