Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146);
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (17769); Uniprot accession (1658); PDB accession (167); 3D entries (47); cryst (2)
All (16450) Archaea (53) Bacteria (15982) Eukaryota (382) unclassified (33) Structure (47 - 2 cryst) Characterized (185)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-galactosidase (LacZ)   Transcriptional reporter pASE222 AFV61209.1    
 ORF   uncultured organism ADD61837.1 D9ZET3  
 ORF   uncultured organism ADD61403.1
ADD62008.1
D9ZDJ9  
 ORF   uncultured organism ADD61823.1 D9ZER9  
 ORF   uncultured organism ADD61508.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02537.1    
 GH2, Betα-galactosidase   uncultured organism VDS02705.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02457.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02485.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02701.1    
 GH2_5, Betα-galactosidase   uncultured organism VDS02704.1    
 GH2, Betα-galactosidase   uncultured organism VDS02461.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02712.1    
 GH2_5, Betα-galactosidase   uncultured organism VDS02507.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02512.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02582.1    
 GH2_5, Betα-galactosidase   uncultured organism VDS02460.1    
 GH2_m2, Betα-mannosidase   uncultured organism VDS02562.1    
 GH2_5, Betα-galactosidase   uncultured organism VDS02717.1    
 ORF (1_11)   uncultured organism AGU09728.1    
 ORF   uncultured organism AGU10257.1    
 ORF   uncultured organism AGU10259.1    
 ORF   uncultured organism AGU10784.1    
 ORF   uncultured organism AGU11236.1    
 ORF (1_19)   uncultured organism AGU09732.1    
 ORF (fragment)   uncultured organism AGU11376.1    
 ORF   uncultured organism AGU11378.1    
 β-galactosidase   uncultured organism AIB09473.1    
 ORF   uncultured prokaryote CRY95609.1    
 ORF (fragment)   uncultured prokaryote CRY95232.1    
 Sequence 25560 from patent US 7504490.   unidentified ACP93342.1    
 ORF   unidentified 6NCW_A    
 Sequence 8 from patent US 7148407   unidentified ABN17154.1    
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