Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146); β-glucosidase (EC 3.2.1.21)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (23444); Uniprot accession (1654); PDB accession (204); 3D entries (52); cryst (2)
All (22115) Archaea (80) Bacteria (21479) Eukaryota (523) unclassified (33) Structure (52 - 2 cryst) Characterized (179)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 KLMA_30009   Kluyveromyces marxianus DMKU3-1042 BAO39304.1    
 β-galactosidase 3.2.1.23 Kluyveromyces marxianus DSM5418 AAS18310.1 Q6QTF4  
 KMAR_30002   Kluyveromyces marxianus NBRC 1777 BAP70807.1    
 LSAL_LOCUS14137 (fragment)   Lactuca saligna CAB4085929.1    
 LSAL_LOCUS11464 (fragment)   Lactuca saligna CAB4083093.1    
 LSAL_LOCUS11414 (fragment)   Lactuca saligna CAB4083040.1    
 LSAL_LOCUS26450 (fragment)   Lactuca saligna CAB4098966.1    
 LSAL_LOCUS39918 (fragment)   Lactuca saligna CAB4113270.1    
 LSAL_LOCUS41794   Lactuca saligna CAB4115255.1    
 LSAL_LOCUS36684 (fragment)   Lactuca saligna CAB4109807.1    
 LSINAPIS_LOCUS3459   Leptidea sinapis VUY90622.1    
 LSINAPIS_LOCUS427   Leptidea sinapis VUY86578.1    
 ORF   Leptinotarsa decemlineata AGX25148.1    
 ORF   Leptosphaeria maculans JN3 CBX97149.1 E4ZZN3  
 ORF   Leptosphaeria maculans JN3 CBX99479.1 E5A784  
 ORF   Leptosphaeria maculans JN3 CBY01311.1 E5ADM2  
 ORF   Leptosphaeria maculans JN3 CBY01568.1 E5AEC9  
 ORF (fragment)   Leptosphaeria maculans JN3 CBX93875.1 E4ZRM8  
 ORF   Leptosphaeria maculans JN3 CBX94573.1    
 ORF   Leptosphaeria maculans JN3 CBX98985.1 E5A5U0  
 mannosylglycoprotein endo-β-mannosidase (Ebm) 3.2.1.152 Lilium longiflorum BAD89079.2
BAD89079.1
Q5H7P5  
 β-glucuronidase (GUSB) (fragment)   Macaca mulatta AAV98539.1 Q4G3Z5  
 β-mannosidase precursor, partial (ManbA) (fragment)   Macaca mulatta AFE73803.1    
 β-glucuronidase precursor (GusB)   Macaca mulatta AFE77962.1
AFE77963.1
   
 β-glucuronidase precursor, partial (GusB) (fragment)   Macaca mulatta AFE67511.1    
 β-mannosidase precursor, partial (ManbA) (fragment)   Macaca mulatta AFE69594.1    
 β-glucuronidase precursor (GusB)   Macaca mulatta AFH28819.1
AFH28820.1
   
 Mp_5g08290   Marchantia polymorpha subsp. ruderalis Tak-1 BBN11008.1    
 Mp_6g04460   Marchantia polymorpha subsp. ruderalis Tak-1 BBN13547.1    
 MtrDRAFT_AC151426g18v1 (partial)   Medicago truncatula ABP03323.1    
 BN887_06040 (fragment)   Melanopsichium pennsylvanicum 4 CDI51778.1    
 G6M90_00g094760 (UidA)   Metarhizium brunneum 4556 QLI73958.1    
 G6M90_00g025880   Metarhizium brunneum 4556 QLI64588.1    
 G6M90_00g073920 (LacZ)   Metarhizium brunneum 4556 QLI71253.1    
 G6M90_00g035710 (Lac4) (fragment)   Metarhizium brunneum 4556 QLI68281.1    
 G6M90_00g066260 (Gls93)   Metarhizium brunneum 4556 QLI69913.1    
 G6M90_00g015540 (MndB)   Metarhizium brunneum 4556 QLI66193.1    
 ORF   Microbiota decussata ATA62835.1    
 MICPUN_51444 (fragment)   Micromonas commoda sp. RCC299 ACO68436.1 C1FDQ8  
 β-glucuronidase (GusB;Gus-S) 3.2.1.31 Mus musculus AAA37696.1
AAA37697.1
AAA63307.1
AAA63308.1
AAA63309.1
AAA98623.1
AAH71226.1
AAQ41980.1
BAE23021.1
BAE29265.1
BAE34865.1
BAE35155.1
BAE35384.1
BAE36917.1
CAC41171.1
NP_034498.1
P12265  
 β-mannosidase 3.2.1.25 Mus musculus AAK18177.1
AAH31409.1
BAE24954.1
BAE38715.1
BAE41690.1
NP_081564.1
Q8K2I4
Q99MS1
6DDT[A]
6DDU[A]
 GusB (fragment)   Mus spretus SPRET/EiJ ALX38052.1    
 ORF   Musca domestica ALHF AFP59583.1    
 ORF (fragment)   Musca domestica ALHF AFP64891.1    
 ORF (fragment)   Musca domestica ALHF AFP65047.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99526.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99527.1    
 ORF (fragment)   Mustela putorius furo AES01514.1    
 lysosomal β-glucuronidase (fragment)   Mytilus galloprovincialis ABY60966.1 B0FN51  
 NGATSA_3040200 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69043.1    
 NGATSA_3032100 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69547.1    
 NCU00985.1 (B20J13.350)   Neurospora crassa OR74A CAE76354.1
XP_325165.1
Q7SGD7  
 NCU05956.1   Neurospora crassa OR74A XP_325811.1    
 NCU00810 (BgaD)   Neurospora crassa OR74A DAA35009.1
XP_324990.1
   
 NCU09042.1   Neurospora crassa OR74A XP_331434.1 Q7S2T3  
 NCU00890.1   Neurospora crassa OR74A XP_325070.1 Q7SFE1  
 Os01g0952600   Oryza sativa Japonica Group BAD87855.1
BAB64698.1
BAF07335.1
BAS76255.1
BAS76256.1
NP_914661.1
Q5JKZ9  
 Os05g0391500   Oryza sativa Japonica Group BAF17358.1
AAV31255.1
BAS93852.1
Q0DIG5  
 OSTLU_119488   Ostreococcus lucimarinus CCE9901 ABO94678.1 A4RT31  
 Ot07g03490   Ostreococcus tauri OTTH0595 CAL54622.1 Q014Q7  
 AMS68_003500   Peltaster fructicola LNHT1506 QIW97982.1    
 AMS68_003460   Peltaster fructicola LNHT1506 QIW97942.1    
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens DSM1215 AAV91787.1 Q5MJY0  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens RPK AAV91785.1 Q5MJY2  
 Pc12g11750   Penicillium rubens Wisconsin 54-1255 CAP80802.1 B6GXQ4  
 Pc12g13420   Penicillium rubens Wisconsin 54-1255 CAP80969.1 B6GZU1  
 Pc16g06840   Penicillium rubens Wisconsin 54-1255 CAP93354.1
CAV33708.1
B6H7F7  
 Pc16g06900   Penicillium rubens Wisconsin 54-1255 CAP93360.1 B6H7G3  
 Pc21g13810   Penicillium rubens Wisconsin 54-1255 CAP96278.1
CAV33710.1
B6HNQ6  
 Pc22g14540   Penicillium rubens Wisconsin 54-1255 CAP98742.1 B6HUZ1  
 β-mannosidase (ManbA)   Phallusia mammillata CAB3263609.1    
 ORF   Phallusia mammillata CAB3251424.1    
 WS02759_M23 (fragment)   Picea sitchensis ABR16858.1 B8LMH8  
 Pa_5_10470   Podospora anserina S mat+ CAP65831.1
CDP30306.1
B2APB4  
 unnamed protein product   Podospora anserina S mat+ CAP59820.1
CDP22463.1
B2A9R0  
 Pa_1_5180 (BgaD)   Podospora anserina S mat+ DAA35011.1
CAP60205.1
CDP22846.1
B2AAU3  
 unnamed protein product   Podospora anserina S mat+ CAP61774.1
CDP28114.1
B2AEA8  
 unnamed protein product   Podospora anserina S mat+ CAP66718.1
CDP28453.1
B2ARE0  
 Pa_1_18330   Podospora anserina S mat+ CAP67962.1
CDP24221.1
B2AU89  
 unnamed protein product   Podospora anserina S mat+ CAP70161.1
CDP26753.1
B2AZW1  
 PODCO_105180   Podospora comata VBB71888.1    
 PODCO_101480   Podospora comata VBB71464.1    
 PODCO_118330   Podospora comata VBB73406.1    
 PODCO_407810 (fragment)   Podospora comata VBB80072.1    
 PODCO_302620   Podospora comata VBB76852.1    
 PODCO_510470   Podospora comata VBB82149.1    
 DKFZp468F089   Pongo abelii CAH91050.1 Q5RB10  
 DKFZp459E0319   Pongo abelii CAH92009.1 Q5R5N6  
 DKFZp469C0414   Pongo abelii CAH92930.1 Q5R5N6  
 DKFZp468F187   Pongo abelii CAH90241.1 Q5RDB6  
 β-glucuronidase (BGLU) (fragment)   Pongo pygmaeus AAL56231.1 Q8WNN1  
 ORF (fragment)   Pristhesancus plagipennis ATU82730.1    
 Prudu_005395   Prunus dulcis BBG96555.1    
 PoMZ_13435   Pyricularia oryzae QBZ66458.1    
 PoMZ_05265   Pyricularia oryzae QBZ63581.1    
 PoMZ_11590   Pyricularia oryzae QBZ62704.1    
 PoMZ_00748   Pyricularia oryzae QBZ55844.1    
 PoMZ_03421   Pyricularia oryzae QBZ58468.1    
 PoMZ_00812   Pyricularia oryzae QBZ55906.1    
 PoMZ_08737   Pyricularia oryzae QBZ61779.1    
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