Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (14087); Uniprot accession (1659); PDB accession (131); 3D entries (31); cryst (2)
All (12797) Archaea (49) Bacteria (12399) Eukaryota (331) unclassified (18) Structure (31 - 2 cryst) Characterized (157)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-glucuronidase (GusB;Gus-S) 3.2.1.31 Mus musculus AAA37696.1
AAA37697.1
AAA63307.1
AAA63308.1
AAA63309.1
AAA98623.1
AAH71226.1
AAQ41980.1
BAE23021.1
BAE29265.1
BAE34865.1
BAE35155.1
BAE35384.1
BAE36917.1
CAC41171.1
NP_034498.1
P12265  
 β-mannosidase 3.2.1.25 Mus musculus AAK18177.1
AAH31409.1
BAE24954.1
BAE38715.1
BAE41690.1
NP_081564.1
Q8K2I4
Q99MS1
 
 GusB (fragment)   Mus spretus SPRET/EiJ ALX38052.1    
 ORF   Musca domestica ALHF AFP59583.1    
 ORF (fragment)   Musca domestica ALHF AFP64891.1    
 ORF (fragment)   Musca domestica ALHF AFP65047.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99526.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99527.1    
 ORF (fragment)   Mustela putorius furo AES01514.1    
 lysosomal β-glucuronidase (fragment)   Mytilus galloprovincialis ABY60966.1 B0FN51  
 NGATSA_3040200 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69043.1    
 NGATSA_3032100 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69547.1    
 NCU00985.1 (B20J13.350)   Neurospora crassa OR74A CAE76354.1
XP_325165.1
Q7SGD7  
 NCU05956.1   Neurospora crassa OR74A XP_325811.1    
 NCU00810 (BgaD)   Neurospora crassa OR74A DAA35009.1
XP_324990.1
   
 NCU09042.1   Neurospora crassa OR74A XP_331434.1 Q7S2T3  
 NCU00890.1   Neurospora crassa OR74A XP_325070.1 Q7SFE1  
 Os01g0952600   Oryza sativa Japonica Group BAD87855.1
BAB64698.1
BAF07335.1
BAS76255.1
BAS76256.1
NP_914661.1
Q5JKZ9  
 Os05g0391500   Oryza sativa Japonica Group BAF17358.1
AAV31255.1
BAS93852.1
Q0DIG5  
 OSTLU_119488   Ostreococcus lucimarinus CCE9901 ABO94678.1 A4RT31  
 Ot07g03490   Ostreococcus tauri OTTH0595 CAL54622.1 Q014Q7  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens DSM1215 AAV91787.1 Q5MJY0  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens RPK AAV91785.1 Q5MJY2  
 Pc12g11750   Penicillium rubens Wisconsin 54-1255 CAP80802.1 B6GXQ4  
 Pc12g13420   Penicillium rubens Wisconsin 54-1255 CAP80969.1 B6GZU1  
 Pc16g06840   Penicillium rubens Wisconsin 54-1255 CAP93354.1
CAV33708.1
B6H7F7  
 Pc16g06900   Penicillium rubens Wisconsin 54-1255 CAP93360.1 B6H7G3  
 Pc21g13810   Penicillium rubens Wisconsin 54-1255 CAP96278.1
CAV33710.1
B6HNQ6  
 Pc22g14540   Penicillium rubens Wisconsin 54-1255 CAP98742.1 B6HUZ1  
 WS02759_M23 (fragment)   Picea sitchensis ABR16858.1 B8LMH8  
 Pa_5_10470   Podospora anserina S mat+ CAP65831.1
CDP30306.1
B2APB4  
 unnamed protein product   Podospora anserina S mat+ CAP59820.1
CDP22463.1
B2A9R0  
 Pa_1_5180 (BgaD)   Podospora anserina S mat+ DAA35011.1
CAP60205.1
CDP22846.1
B2AAU3  
 unnamed protein product   Podospora anserina S mat+ CAP61774.1
CDP28114.1
B2AEA8  
 unnamed protein product   Podospora anserina S mat+ CAP66718.1
CDP28453.1
B2ARE0  
 Pa_1_18330   Podospora anserina S mat+ CAP67962.1
CDP24221.1
B2AU89  
 unnamed protein product   Podospora anserina S mat+ CAP70161.1
CDP26753.1
B2AZW1  
 DKFZp468F089   Pongo abelii CAH91050.1 Q5RB10  
 DKFZp459E0319   Pongo abelii CAH92009.1 Q5R5N6  
 DKFZp469C0414   Pongo abelii CAH92930.1 Q5R5N6  
 DKFZp468F187   Pongo abelii CAH90241.1 Q5RDB6  
 β-glucuronidase (BGLU) (fragment)   Pongo pygmaeus AAL56231.1 Q8WNN1  
 ORF (fragment)   Pristhesancus plagipennis ATU82730.1    
 Unknown (protein for MGC:116230)   Rattus norvegicus AAH99094.1
AAI11711.1
Q4FZV0  
 β-glucuronidase (GusB;Gus) 3.2.1.31 Rattus norvegicus AAA41228.1
AAP86274.1
CAA68705.1
NP_058711.1
P06760
Q7TPJ3
 
 RHTO0S_07e08790g   Rhodotorula toruloides CECT1137 CDR43143.1    
 PICST_30036   Scheffersomyces stipitis CBS 6054 ABN64540.1
ABN64540.2
   
 PICST_43820   Scheffersomyces stipitis CBS 6054 ABN65300.2
ABN65300.1
   
 SJCHGC07237 (fragment)   Schistosoma japonicum AAX25842.2 Q5C3D3  
 Smp_137150   Schistosoma mansoni Puerto Rico CAZ30440.1
CCD79187.1
C4Q4Q9  
 sscle_05g045850   Sclerotinia sclerotiorum 1980 UF-70 APA09815.1    
 sscle_12g091670 (fragment)   Sclerotinia sclerotiorum 1980 UF-70 APA14397.1    
 SMAX5B_004065   Scophthalmus maximus AWP00424.1    
 SMAX5B_009121   Scophthalmus maximus AWP16047.1    
 β-glucuronidase (Gus) 3.2.1.31 Scopulariopsis sp. RP38.3 AAV91788.1 Q5MJX9  
 PIIN_00917   Serendipita indica DSM 11827 CCA67082.1    
 PIIN_01338   Serendipita indica DSM 11827 CCA67509.1    
 ORF (fragment)   Spodoptera litura AGV76307.1    
 SRS1_13138   Sporisorium reilianum f. sp. reilianum SRS1_H2-8 SJX62291.1    
 sr13138   Sporisorium reilianum SRZ2 CBQ72430.1    
 SPSC_05930   Sporisorium scitamineum SscI8 CDU25759.1    
 SPSC_03919   Sporisorium scitamineum SscI8 CDR88258.1    
 SRAE_2000082500   Strongyloides ratti ED321 Heterogonic CEF66155.1    
 SRAE_2000069700   Strongyloides ratti ED321 Heterogonic CEF66024.1    
 AWJ20_1966   Sugiyamaella lignohabitans CBS 10342 ANB14378.1    
 AWJ20_1932   Sugiyamaella lignohabitans CBS 10342 ANB13633.1    
 AWJ20_2544   Sugiyamaella lignohabitans CBS 10342 ANB14927.1    
 β-glucuronidase (GusB)   Sus scrofa AAZ03639.1 Q4FAT7  
 MYCTH_90655 (Man9)   Thermothelomyces thermophila ATCC 42464 AEO53082.1    
 MYCTH_2295445   Thermothelomyces thermophila ATCC 42464 AEO53731.1    
 MYCTH_2094324   Thermothelomyces thermophila ATCC 42464 AEO59187.1    
 MYCTH_2307767   Thermothelomyces thermophila ATCC 42464 AEO59435.1    
 MYCTH_54601   Thermothelomyces thermophila ATCC 42464 AEO60310.1    
 MYCTH_114497   Thermothelomyces thermophila ATCC 42464 AEO54508.1    
 MYCTH_40111   Thermothelomyces thermophila ATCC 42464 AEO55648.1    
 β-mannosidase (Man9;bMann9) 3.2.1.25 Thermothelomyces thermophila C1 AFJ59925.1 I2C092  
 THITE_2110051   Thielavia terrestris NRRL 8126 AEO64183.1    
 THITE_2110638   Thielavia terrestris NRRL 8126 AEO64472.1    
 THITE_2112614   Thielavia terrestris NRRL 8126 AEO65527.1    
 THITE_2046339   Thielavia terrestris NRRL 8126 AEO66261.1    
 THITE_2049779   Thielavia terrestris NRRL 8126 AEO67616.1    
 THITE_2120695   Thielavia terrestris NRRL 8126 AEO69937.1    
 THITE_124733   Thielavia terrestris NRRL 8126 AEO71826.1    
 THITE_2109377   Thielavia terrestris NRRL 8126 AEO63777.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55460.1    
 β-mannosidase (ThMan2A) (Man2A)   Trichoderma harzianum IOC-3844 AID21733.1   4CVU[A]
4UOJ[A,B]
 exo-β-glucosaminidase (Gls93) 3.2.1.165 Trichoderma reesei PC-3-7 BAD99604.1 Q4R1C4 cryst
 exo-β-glucosaminidase (Gls1)   Trichoderma virens ACN62417.1 C0LRA7  
 β-galactosidase   Trichomonas vaginalis ABL07608.1 A1E4C9  
 TRAES_3BF136000070CFD_c1   Triticum aestivum CDM84253.1    
 β-galactosidase   Tritrichomonas foetus ARM19942.1    
 UBRO_16798   Ustilago bromivora UB2112 SAM74999.1    
 UBRO_03214   Ustilago bromivora UB2112 SAM81680.1    
 VIGAN_08171100 (Vigan.08g171100)   Vigna angularis var. angularis BAT95051.1    
 VIGAN_06019100 (Vigan.06g019100)   Vigna angularis var. angularis BAT89274.1    
 VIGAN_05149200 (Vigan.05g149200)   Vigna angularis var. angularis BAT88054.1    
 VITISV_002311   Vitis vinifera CAN82620.1 A5AVM0  
 glycoside hydrolase family 2 protein   Xanthophyllomyces dendrorhous CED84166.1    
 Unknown (protein for MGC:82825)   Xenopus laevis AAH78052.1 Q6DCI1  
 ZT1A5_G6342   Zymoseptoria tritici ST99CH_1A5 SMY24900.1    
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