Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146);
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (17769); Uniprot accession (1658); PDB accession (167); 3D entries (47); cryst (2)
All (16450) Archaea (53) Bacteria (15982) Eukaryota (382) unclassified (33) Structure (47 - 2 cryst) Characterized (185)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF   Leptinotarsa decemlineata AGX25148.1    
 ORF   Leptosphaeria maculans JN3 CBX97149.1 E4ZZN3  
 ORF   Leptosphaeria maculans JN3 CBX99479.1 E5A784  
 ORF   Leptosphaeria maculans JN3 CBY01311.1 E5ADM2  
 ORF   Leptosphaeria maculans JN3 CBY01568.1 E5AEC9  
 ORF (fragment)   Leptosphaeria maculans JN3 CBX93875.1 E4ZRM8  
 ORF   Leptosphaeria maculans JN3 CBX94573.1    
 ORF   Leptosphaeria maculans JN3 CBX98985.1 E5A5U0  
 mannosylglycoprotein endo-β-mannosidase (Ebm) 3.2.1.152 Lilium longiflorum BAD89079.2
BAD89079.1
Q5H7P5  
 β-glucuronidase (GUSB) (fragment)   Macaca mulatta AAV98539.1 Q4G3Z5  
 β-mannosidase precursor, partial (ManbA) (fragment)   Macaca mulatta AFE73803.1    
 β-glucuronidase precursor (GusB)   Macaca mulatta AFE77962.1
AFE77963.1
   
 β-glucuronidase precursor, partial (GusB) (fragment)   Macaca mulatta AFE67511.1    
 β-mannosidase precursor, partial (ManbA) (fragment)   Macaca mulatta AFE69594.1    
 β-glucuronidase precursor (GusB)   Macaca mulatta AFH28819.1
AFH28820.1
   
 MtrDRAFT_AC151426g18v1 (partial)   Medicago truncatula ABP03323.1    
 BN887_06040 (fragment)   Melanopsichium pennsylvanicum 4 CDI51778.1    
 ORF   Microbiota decussata ATA62835.1    
 MICPUN_51444 (fragment)   Micromonas commoda sp. RCC299 ACO68436.1 C1FDQ8  
 β-glucuronidase (GusB;Gus-S) 3.2.1.31 Mus musculus AAA37696.1
AAA37697.1
AAA63307.1
AAA63308.1
AAA63309.1
AAA98623.1
AAH71226.1
AAQ41980.1
BAE23021.1
BAE29265.1
BAE34865.1
BAE35155.1
BAE35384.1
BAE36917.1
CAC41171.1
NP_034498.1
P12265  
 β-mannosidase 3.2.1.25 Mus musculus AAK18177.1
AAH31409.1
BAE24954.1
BAE38715.1
BAE41690.1
NP_081564.1
Q8K2I4
Q99MS1
6DDT[A]
6DDU[A]
 GusB (fragment)   Mus spretus SPRET/EiJ ALX38052.1    
 ORF   Musca domestica ALHF AFP59583.1    
 ORF (fragment)   Musca domestica ALHF AFP64891.1    
 ORF (fragment)   Musca domestica ALHF AFP65047.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99526.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99527.1    
 ORF (fragment)   Mustela putorius furo AES01514.1    
 lysosomal β-glucuronidase (fragment)   Mytilus galloprovincialis ABY60966.1 B0FN51  
 NGATSA_3040200 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69043.1    
 NGATSA_3032100 (fragment)   Nannochloropsis gaditana CCMP526 AFJ69547.1    
 NCU00985.1 (B20J13.350)   Neurospora crassa OR74A CAE76354.1
XP_325165.1
Q7SGD7  
 NCU05956.1   Neurospora crassa OR74A XP_325811.1    
 NCU00810 (BgaD)   Neurospora crassa OR74A DAA35009.1
XP_324990.1
   
 NCU09042.1   Neurospora crassa OR74A XP_331434.1 Q7S2T3  
 NCU00890.1   Neurospora crassa OR74A XP_325070.1 Q7SFE1  
 Os01g0952600   Oryza sativa Japonica Group BAD87855.1
BAB64698.1
BAF07335.1
BAS76255.1
BAS76256.1
NP_914661.1
Q5JKZ9  
 Os05g0391500   Oryza sativa Japonica Group BAF17358.1
AAV31255.1
BAS93852.1
Q0DIG5  
 OSTLU_119488   Ostreococcus lucimarinus CCE9901 ABO94678.1 A4RT31  
 Ot07g03490   Ostreococcus tauri OTTH0595 CAL54622.1 Q014Q7  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens DSM1215 AAV91787.1 Q5MJY0  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens RPK AAV91785.1 Q5MJY2  
 Pc12g11750   Penicillium rubens Wisconsin 54-1255 CAP80802.1 B6GXQ4  
 Pc12g13420   Penicillium rubens Wisconsin 54-1255 CAP80969.1 B6GZU1  
 Pc16g06840   Penicillium rubens Wisconsin 54-1255 CAP93354.1
CAV33708.1
B6H7F7  
 Pc16g06900   Penicillium rubens Wisconsin 54-1255 CAP93360.1 B6H7G3  
 Pc21g13810   Penicillium rubens Wisconsin 54-1255 CAP96278.1
CAV33710.1
B6HNQ6  
 Pc22g14540   Penicillium rubens Wisconsin 54-1255 CAP98742.1 B6HUZ1  
 WS02759_M23 (fragment)   Picea sitchensis ABR16858.1 B8LMH8  
 Pa_5_10470   Podospora anserina S mat+ CAP65831.1
CDP30306.1
B2APB4  
 unnamed protein product   Podospora anserina S mat+ CAP59820.1
CDP22463.1
B2A9R0  
 Pa_1_5180 (BgaD)   Podospora anserina S mat+ DAA35011.1
CAP60205.1
CDP22846.1
B2AAU3  
 unnamed protein product   Podospora anserina S mat+ CAP61774.1
CDP28114.1
B2AEA8  
 unnamed protein product   Podospora anserina S mat+ CAP66718.1
CDP28453.1
B2ARE0  
 Pa_1_18330   Podospora anserina S mat+ CAP67962.1
CDP24221.1
B2AU89  
 unnamed protein product   Podospora anserina S mat+ CAP70161.1
CDP26753.1
B2AZW1  
 PODCO_105180   Podospora comata VBB71888.1    
 PODCO_101480   Podospora comata VBB71464.1    
 PODCO_118330   Podospora comata VBB73406.1    
 PODCO_407810 (fragment)   Podospora comata VBB80072.1    
 PODCO_302620   Podospora comata VBB76852.1    
 PODCO_510470   Podospora comata VBB82149.1    
 DKFZp468F089   Pongo abelii CAH91050.1 Q5RB10  
 DKFZp459E0319   Pongo abelii CAH92009.1 Q5R5N6  
 DKFZp469C0414   Pongo abelii CAH92930.1 Q5R5N6  
 DKFZp468F187   Pongo abelii CAH90241.1 Q5RDB6  
 β-glucuronidase (BGLU) (fragment)   Pongo pygmaeus AAL56231.1 Q8WNN1  
 ORF (fragment)   Pristhesancus plagipennis ATU82730.1    
 Prudu_005395   Prunus dulcis BBG96555.1    
 PoMZ_13435   Pyricularia oryzae QBZ66458.1    
 PoMZ_05265   Pyricularia oryzae QBZ63581.1    
 PoMZ_11590   Pyricularia oryzae QBZ62704.1    
 PoMZ_00748   Pyricularia oryzae QBZ55844.1    
 PoMZ_03421   Pyricularia oryzae QBZ58468.1    
 PoMZ_00812   Pyricularia oryzae QBZ55906.1    
 PoMZ_08737   Pyricularia oryzae QBZ61779.1    
 PoMZ_03538   Pyricularia oryzae QBZ58582.1    
 MG05890.4   Pyricularia oryzae 70-15 XP_369574.1 G4N3Y7  
 MG05864.4   Pyricularia oryzae 70-15 XP_369600.1 G4N3R3  
 MG00583.4   Pyricularia oryzae 70-15 XP_368661.1 G4NBB5  
 MG09664.4   Pyricularia oryzae 70-15 XP_364819.1 Q2KHA3  
 MG08964.4   Pyricularia oryzae 70-15 XP_364119.1 G4MW41  
 MGG_13801   Pyricularia oryzae 70-15 XP_003710906.1    
 MGG_01178   Pyricularia oryzae 70-15 XP_003714062.1
XP_363252.1
   
 MGG_13610   Pyricularia oryzae 70-15 XP_003717495.1    
 Unknown (protein for MGC:116230)   Rattus norvegicus AAH99094.1
AAI11711.1
Q4FZV0  
 β-glucuronidase (GusB;Gus) 3.2.1.31 Rattus norvegicus AAA41228.1
AAP86274.1
CAA68705.1
NP_058711.1
P06760
Q7TPJ3
 
 RHTO0S_07e08790g   Rhodotorula toruloides CECT1137 CDR43143.1    
 PICST_30036   Scheffersomyces stipitis CBS 6054 ABN64540.1
ABN64540.2
   
 PICST_43820   Scheffersomyces stipitis CBS 6054 ABN65300.2
ABN65300.1
   
 SJCHGC07237 (fragment)   Schistosoma japonicum AAX25842.2 Q5C3D3  
 Smp_137150   Schistosoma mansoni Puerto Rico CAZ30440.1
CCD79187.1
C4Q4Q9  
 sscle_05g045850   Sclerotinia sclerotiorum 1980 UF-70 APA09815.1    
 sscle_12g091670 (fragment)   Sclerotinia sclerotiorum 1980 UF-70 APA14397.1    
 SMAX5B_004065   Scophthalmus maximus AWP00424.1    
 SMAX5B_009121   Scophthalmus maximus AWP16047.1    
 β-glucuronidase (Gus) 3.2.1.31 Scopulariopsis sp. RP38.3 AAV91788.1 Q5MJX9  
 PIIN_00917   Serendipita indica DSM 11827 CCA67082.1    
 PIIN_01338   Serendipita indica DSM 11827 CCA67509.1    
 ORF (fragment)   Spodoptera litura AGV76307.1    
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