Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146); β-glucosidase (EC 3.2.1.21)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (23444); Uniprot accession (1654); PDB accession (204); 3D entries (52); cryst (2)
All (22115) Archaea (80) Bacteria (21479) Eukaryota (523) unclassified (33) Structure (52 - 2 cryst) Characterized (179)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 FGRAMPH1_01T12595   Fusarium graminearum PH-1 SCB65794.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF71940.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72811.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF74591.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79733.1    
 ORF   Fusarium oxysporum f. sp. fragariae BAD89519.1 Q5FBG0  
 FOBC_00489   Fusarium oxysporum Fo47 QKD46514.1    
 FOBC_04576   Fusarium oxysporum Fo47 QKD50538.1    
 FOBC_00776   Fusarium oxysporum Fo47 QKD46795.1    
 FOBC_04440   Fusarium oxysporum Fo47 QKD50402.1    
 FOBC_04592   Fusarium oxysporum Fo47 QKD50554.1    
 FOBC_08950   Fusarium oxysporum Fo47 QKD54841.1    
 FOBC_10762   Fusarium oxysporum Fo47 QKD56624.1    
 FOBC_11455   Fusarium oxysporum Fo47 QKD57317.1    
 FOBC_14800   Fusarium oxysporum Fo47 QKD60619.1    
 FOBC_14656   Fusarium oxysporum Fo47 QKD60479.1    
 FOBC_12089   Fusarium oxysporum Fo47 QKD57951.1    
 ORF   Fusarium sp. IFO 7772 BAD89516.1 Q5FBG3  
 FVRRES_00197   Fusarium venenatum A3/5 CEI63685.1    
 FVRRES_06203   Fusarium venenatum A3/5 CEI61767.1    
 FVRRES_04459 (fragment)   Fusarium venenatum A3/5 CEI60023.1    
 FVRRES_10429   Fusarium venenatum A3/5 CEI70352.1    
 FVRRES_02846   Fusarium venenatum A3/5 CEI66334.1    
 FVRRES_12650   Fusarium venenatum A3/5 CEI39959.1    
 FVRRES_06264   Fusarium venenatum A3/5 CEI61828.1    
 FVRRES_12417   Fusarium venenatum A3/5 CEI39726.1    
 FVRRES_02707   Fusarium venenatum A3/5 CEI66195.1    
 FVRRES_08146   Fusarium venenatum A3/5 CEI68069.1    
 FVRRES_01016   Fusarium venenatum A3/5 CEI64504.1    
 FVRRES_00089   Fusarium venenatum A3/5 CEI63577.1    
 RCJMB04_28l23   Gallus gallus CAG32539.1 Q5ZIA4  
 ORF   Ganoderma boninense VWO95209.1    
 β-glucuronidase (BGLU) (fragment)   Gorilla gorilla AAL56230.1 Q8WNN2  
 β-mannosidase   Gossypium aridum AEN70959.1    
 β-mannosidase   Gossypium armourianum AEN70955.1    
 ManA2   Gossypium barbadense ADZ16125.1    
 ManA2 (fragment)   Gossypium barbadense ADZ16124.1    
 β-mannosidase   Gossypium barbadense var. brasiliense AEN70950.1    
 β-mannosidase (fragment)   Gossypium barbadense var. brasiliense AEN70949.1    
 β-mannosidase   Gossypium barbadense var. peruvianum AEN70952.1    
 β-mannosidase (fragment)   Gossypium barbadense var. peruvianum AEN70951.1    
 β-mannosidase (fragment)   Gossypium darwinii AEN70945.1    
 β-mannosidase   Gossypium darwinii AEN70946.1    
 β-mannosidase   Gossypium davidsonii AEN70957.1    
 β-mannosidase   Gossypium gossypioides AEN70960.1    
 β-mannosidase   Gossypium harknessii AEN70956.1    
 ManA2   Gossypium herbaceum subsp. africanum ADZ16126.1    
 β-mannosidase   Gossypium hirsutum subsp. latifolium AEN70954.1    
 β-mannosidase   Gossypium hirsutum subsp. latifolium AEN70953.1    
 ORF   Gossypium hirsutum TM-1 AAO27794.1
AAK84953.2
ADZ16128.1
ADZ16129.1
Q84XI2
Q93X75
 
 β-mannosidase   Gossypium klotzschianum AEN70958.1    
 β-mannosidase   Gossypium laxum AEN70940.1    
 β-mannosidase   Gossypium lobatum AEN70961.1    
 β-mannosidase   Gossypium mustelinum AEN70944.1    
 β-mannosidase   Gossypium mustelinum AEN70943.1    
 glycosyl hydrolase (Mana2)   Gossypium raimondii ADZ16127.1    
 β-mannosidase   Gossypium schwendimanii AEN70941.1    
 β-mannosidase   Gossypium thurberi AEN70939.1    
 β-mannosidase   Gossypium tomentosum AEN70948.1    
 β-mannosidase (fragment)   Gossypium tomentosum AEN70947.1    
 β-mannosidase   Gossypium trilobum AEN70962.1    
 β-mannosidase   Gossypium turneri AEN70942.1    
 ORF   Hesperocyparis arizonica ATA62824.1    
 ORF   Hesperocyparis bakeri ATA62825.1    
 ORF   Hesperocyparis macrocarpa ATA62826.1    
 β-glucuronidase b (GusB;GUSB) 3.2.1.31 Homo sapiens AAA52561.1
AAH14142.1
AAQ96851.1
AAR75622.1
ABH92596.1
ACH09936.1
ACM86199.1
BAD97126.1
BAG35619.1
BAG61991.1
BAG64768.1
CAC41170.1
NP_000172.1
P08236 1BHG[A,B]
3HN3[A,B,D,E]
 β-mannosidase (ManBA) 3.2.1.25 Homo sapiens AAC39573.1
AAH15743.1
ABS29701.1
BAD93083.1
BAF84287.1
BAG61830.1
O00462  
 EmGFP-LacZ TdTom, partial (Emgfp-lacz-e2f-tdtoM)   Homo sapiens CAA9893810.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56497.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56458.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56481.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56492.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56474.1    
 ORF (GusB)   Ictalurus punctatus AHH39810.1    
 ORF   Juniperus drupacea ATA62827.1    
 ORF   Juniperus flaccida ATA62828.1    
 ORF   Juniperus indica ATA62829.1    
 ORF   Juniperus microsperma ATA62830.1    
 ORF   Juniperus oxycedrus ATA62831.1    
 ORF   Juniperus phoenicea ATA62832.1    
 ORF   Juniperus procera ATA62833.1    
 ORF   Juniperus scopulorum ATA62834.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis CBS 683 QLH93946.1    
 β-galactosidase (Lac4;BgaL) 3.2.1.23 Kluyveromyces lactis CBS2359 AAA35265.1 P00723 3OB8[A,B,C,D]
3OBA[A,B,C,D]
 β-galactosidase (BglKL) 3.2.1.23 Kluyveromyces lactis F61 AHW49176.1    
 β-D-galactosidase, partial (Lac4) (fragment)   Kluyveromyces lactis LMA-437 AEM17344.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis NRRL Y-1118 QLH93941.1    
 β-galactosidase (BgaL;KLLA0B14883g) 3.2.1.23 Kluyveromyces lactis NRRL Y-1140 CAH02587.1 P00723  
 β-galactosidase (Lac4)   Kluyveromyces lactis SM48.7 QLH93947.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-1186 QLH93948.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-1333 QLH93949.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-1339 QLH93951.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-1343 QLH93950.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-1527 QLH93944.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-869 QLH93943.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKM Y-870 QLH93942.1    
 β-galactosidase (Lac4)   Kluyveromyces lactis VKPM Y-3737 QLH93945.1    
 β-galactosidase (Lac4)   Kluyveromyces marxianus CBS 397 QLH93952.1    
 FIM1_1709   Kluyveromyces marxianus CBS4857 QGN15025.1    
 FIM1_2437 (fragment)   Kluyveromyces marxianus CBS4857 QGN15743.1    
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