Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146);
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (17769); Uniprot accession (1658); PDB accession (167); 3D entries (47); cryst (2)
All (16450) Archaea (53) Bacteria (15982) Eukaryota (382) unclassified (33) Structure (47 - 2 cryst) Characterized (185)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Dbus_chr2Rg1703   Drosophila busckii ALC42124.1    
 CG12582   Drosophila melanogaster AAF52172.2
AAF52171.2
AAF52171.3
AAF52171.4
AAN71636.1
AAX33506.1
AFH06218.1
AGB95624.1
AGB95625.1
NP_649436.2
Q8IGB2
Q9VMY5
 
 CG2135   Drosophila melanogaster AAF57195.1
AAQ22542.1
NP_651893.1
Q9V9T9  
 CG15117   Drosophila melanogaster AAM68434.1
AAF57602.2
AAL39474.1
AAS93746.1
AAX52695.1
ACV88434.1
AEZ68804.1
AHN56394.1
AHN56395.1
AHN56396.1
NP_611395.1
NP_725851.1
A1ZBG9  
 ORF (fragment)   Equus caballus AEP98750.1    
 β-glucuronidase (fragment)   Equus caballus ABO86717.1 A4USH5  
 AW171_hschr74493   Eremothecium sinecaudum ATCC 58844 AMD22455.1    
 β-glucuronidase (GusB) 3.2.1.31 Felis catus AAD01498.1
AAD01499.1
O97524  
 ORF (fragment)   Fusarium fujikuroi BAD89523.2 Q5FBF6  
 FFUJ_00422   Fusarium fujikuroi IMI 58289 CCT62972.1    
 FFUJ_14419   Fusarium fujikuroi IMI 58289 CCT66619.1    
 FFUJ_03676   Fusarium fujikuroi IMI 58289 CCT66634.1    
 FFUJ_07764   Fusarium fujikuroi IMI 58289 CCT68937.1    
 FFUJ_09158   Fusarium fujikuroi IMI 58289 CCT70824.1    
 FFUJ_10234   Fusarium fujikuroi IMI 58289 CCT74191.1    
 FFUJ_10765   Fusarium fujikuroi IMI 58289 CCT74702.1    
 FFUJ_10887   Fusarium fujikuroi IMI 58289 CCT74817.1    
 FFUJ_00085   Fusarium fujikuroi IMI 58289 CCT63282.1    
 ORF   Fusarium graminearum F15 BAD89513.1 Q5FBG6  
 FGRAMPH1_01T05857   Fusarium graminearum PH-1 SCB64422.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF84800.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78036.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF83262.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF87867.1    
 FGRAMPH1_01T12595   Fusarium graminearum PH-1 SCB65794.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF71940.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF72811.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF74591.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF79733.1    
 ORF   Fusarium oxysporum f. sp. fragariae BAD89519.1 Q5FBG0  
 ORF   Fusarium sp. IFO 7772 BAD89516.1 Q5FBG3  
 FVRRES_00197   Fusarium venenatum A3/5 CEI63685.1    
 FVRRES_06203   Fusarium venenatum A3/5 CEI61767.1    
 FVRRES_04459 (fragment)   Fusarium venenatum A3/5 CEI60023.1    
 FVRRES_10429   Fusarium venenatum A3/5 CEI70352.1    
 FVRRES_02846   Fusarium venenatum A3/5 CEI66334.1    
 FVRRES_12650   Fusarium venenatum A3/5 CEI39959.1    
 FVRRES_06264   Fusarium venenatum A3/5 CEI61828.1    
 FVRRES_12417   Fusarium venenatum A3/5 CEI39726.1    
 FVRRES_02707   Fusarium venenatum A3/5 CEI66195.1    
 FVRRES_08146   Fusarium venenatum A3/5 CEI68069.1    
 FVRRES_01016   Fusarium venenatum A3/5 CEI64504.1    
 FVRRES_00089   Fusarium venenatum A3/5 CEI63577.1    
 RCJMB04_28l23   Gallus gallus CAG32539.1 Q5ZIA4  
 β-glucuronidase (BGLU) (fragment)   Gorilla gorilla AAL56230.1 Q8WNN2  
 β-mannosidase   Gossypium aridum AEN70959.1    
 β-mannosidase   Gossypium armourianum AEN70955.1    
 ManA2   Gossypium barbadense ADZ16125.1    
 ManA2 (fragment)   Gossypium barbadense ADZ16124.1    
 β-mannosidase   Gossypium barbadense var. brasiliense AEN70950.1    
 β-mannosidase (fragment)   Gossypium barbadense var. brasiliense AEN70949.1    
 β-mannosidase   Gossypium barbadense var. peruvianum AEN70952.1    
 β-mannosidase (fragment)   Gossypium barbadense var. peruvianum AEN70951.1    
 β-mannosidase (fragment)   Gossypium darwinii AEN70945.1    
 β-mannosidase   Gossypium darwinii AEN70946.1    
 β-mannosidase   Gossypium davidsonii AEN70957.1    
 β-mannosidase   Gossypium gossypioides AEN70960.1    
 β-mannosidase   Gossypium harknessii AEN70956.1    
 ManA2   Gossypium herbaceum subsp. africanum ADZ16126.1    
 β-mannosidase   Gossypium hirsutum subsp. latifolium AEN70954.1    
 β-mannosidase   Gossypium hirsutum subsp. latifolium AEN70953.1    
 ORF   Gossypium hirsutum TM-1 AAO27794.1
AAK84953.2
ADZ16128.1
ADZ16129.1
Q84XI2
Q93X75
 
 β-mannosidase   Gossypium klotzschianum AEN70958.1    
 β-mannosidase   Gossypium laxum AEN70940.1    
 β-mannosidase   Gossypium lobatum AEN70961.1    
 β-mannosidase   Gossypium mustelinum AEN70944.1    
 β-mannosidase   Gossypium mustelinum AEN70943.1    
 glycosyl hydrolase (Mana2)   Gossypium raimondii ADZ16127.1    
 β-mannosidase   Gossypium schwendimanii AEN70941.1    
 β-mannosidase   Gossypium thurberi AEN70939.1    
 β-mannosidase   Gossypium tomentosum AEN70948.1    
 β-mannosidase (fragment)   Gossypium tomentosum AEN70947.1    
 β-mannosidase   Gossypium trilobum AEN70962.1    
 β-mannosidase   Gossypium turneri AEN70942.1    
 ORF   Hesperocyparis arizonica ATA62824.1    
 ORF   Hesperocyparis bakeri ATA62825.1    
 ORF   Hesperocyparis macrocarpa ATA62826.1    
 β-glucuronidase b (GusB;GUSB) 3.2.1.31 Homo sapiens AAA52561.1
AAH14142.1
AAQ96851.1
AAR75622.1
ABH92596.1
ACH09936.1
ACM86199.1
BAD97126.1
BAG35619.1
BAG61991.1
BAG64768.1
CAC41170.1
NP_000172.1
P08236 1BHG[A,B]
3HN3[A,B,D,E]
 β-mannosidase (ManBA) 3.2.1.25 Homo sapiens AAC39573.1
AAH15743.1
ABS29701.1
BAD93083.1
BAF84287.1
BAG61830.1
O00462  
 ORF   Hypocrella siamensis MTCC 10142 ANH56497.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56458.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56481.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56492.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56474.1    
 ORF (GusB)   Ictalurus punctatus AHH39810.1    
 ORF   Juniperus drupacea ATA62827.1    
 ORF   Juniperus flaccida ATA62828.1    
 ORF   Juniperus indica ATA62829.1    
 ORF   Juniperus microsperma ATA62830.1    
 ORF   Juniperus oxycedrus ATA62831.1    
 ORF   Juniperus phoenicea ATA62832.1    
 ORF   Juniperus procera ATA62833.1    
 ORF   Juniperus scopulorum ATA62834.1    
 β-galactosidase (Lac4;BgaL) 3.2.1.23 Kluyveromyces lactis CBS2359 AAA35265.1 P00723 3OB8[A,B,C,D]
3OBA[A,B,C,D]
 β-galactosidase (BglKL) 3.2.1.23 Kluyveromyces lactis F61 AHW49176.1    
 β-D-galactosidase, partial (Lac4) (fragment)   Kluyveromyces lactis LMA-437 AEM17344.1    
 β-galactosidase (BgaL;KLLA0B14883g) 3.2.1.23 Kluyveromyces lactis NRRL Y-1140 CAH02587.1 P00723  
 KLMA_30009   Kluyveromyces marxianus DMKU3-1042 BAO39304.1    
 β-galactosidase 3.2.1.23 Kluyveromyces marxianus DSM5418 AAS18310.1 Q6QTF4  
 KMAR_30002   Kluyveromyces marxianus NBRC 1777 BAP70807.1    
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