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Glycoside Hydrolase Family 2

Known Activitiesβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; InterPro; PFAM; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (3065); Uniprot accession (1572); PDB accession (83); 3D entries (13); cryst (1)
Summary
All (2468) Archaea (33) Bacteria (2264) Eukaryota (164) unclassified (7) Structure (13 - 1 cryst) Characterized (123)
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 ALNC14_117850 (Alnc14c309g10482)   Albugo laibachii Nc14 CCA25641.1    
 β-mannosidase (AkMnsD)   Aplysia kurodai BAL43431.1    
 At1g09010/F7G19.12 (mannosylglycoprotein endo-β-mannosidase; AtEBM) 3.2.1.152 Arabidopsis thaliana AAB70407.1
AAK76608.1
AAM14288.1
AEE28382.1
BAD15284.1
NP_172375.1
NP_563833.1		 O04029
Q75W54		  
 At3g54440/T14E10_10   Arabidopsis thaliana AAM10327.1
AEE79230.1
AEE79231.1
AEE79232.1
BAD95157.1
BAE98865.1
CAB77564.1
NP_680128.1		 Q8RWQ2
Q9M1I3		  
 ORF   Ascaris suum ADY43651.1    
 ORF (fragment)   Ascaris suum ADY44885.1    
 β-mannosidase (ManB) (probable frameshift) 3.2.1.25 Aspergillus aculeatus F-50 BAA29029.1 O74168  
 ANIA_01107 (AN1107.2) (fragment)   Aspergillus nidulans FGSC A4 CBF88126.1
EAA66225.1		 C8VTE0  
 AN2395.2   Aspergillus nidulans FGSC A4 EAA64506.1 C8VNQ2  
 AN6388.2   Aspergillus nidulans FGSC A4 EAA58410.1 C8V0P8  
 AN5361.2   Aspergillus nidulans FGSC A4 EAA62521.1 C8VGR3  
 AN3200.2   Aspergillus nidulans FGSC A4 EAA62925.1 C8VIB0  
 β-mannosidase (AN3368.2) 3.2.1.25 Aspergillus nidulans FGSC A4 ABF50864.1
EAA63336.1		    
 AN2824.2   Aspergillus nidulans FGSC A4 EAA63395.1 C8VJG7  
 AN3201.2   Aspergillus nidulans FGSC A4 ABF50859.1
EAA62926.1		 C8VIA9  
 ANIA_01742 (AN1742.2)   Aspergillus nidulans FGSC A4 CBF85479.1
EAA64028.1		 C8VP45  
 AN2463.2   Aspergillus nidulans FGSC A4 EAA64169.1 C8VP83  
 β-mannosidase (MndA) (Mnd2A) 3.2.1.25 Aspergillus niger CBS 120.49 / N400 CAB63902.1 Q9UUZ3  
 An01g01260   Aspergillus niger CBS 513.88 CAK36851.1 A2Q7M5  
 An01g06630   Aspergillus niger CBS 513.88 CAK43782.1 A2Q948  
 An02g00610   Aspergillus niger CBS 513.88 CAK96276.1 A2QBM9  
 An05g02410   Aspergillus niger CBS 513.88 CAK44902.1 A2QL36  
 An11g06540 (MndA) 3.2.1.25 Aspergillus niger CBS 513.88 CAK96951.1 A2QWU9  
 An12g01850   Aspergillus niger CBS 513.88 CAK48467.1
CAV33671.1		 A2QYN2  
 AO090005000740   Aspergillus oryzae RIB40 BAE55770.1    
 AO090001000556   Aspergillus oryzae RIB40 BAE57065.1    
 AO090003001410   Aspergillus oryzae RIB40 BAE58464.1    
 AO090023000053   Aspergillus oryzae RIB40 BAE58640.1    
 AO090012000389   Aspergillus oryzae RIB40 BAE60574.1    
 AO090038000009 (probable fragment)   Aspergillus oryzae RIB40 BAE63869.1    
 AO090010000208   Aspergillus oryzae RIB40 BAE66106.1    
 exo-β-glucosaminidase (Csx) 3.2.1.165 Aspergillus sp. CJ22-326 ACO94980.1 C3U4R9  
 β-glucuronidase   Aspergillus terreus AEP39213.1    
 β-glucuronidase   Aspergillus ustus AEK69352.1    
 β-mannosidase 3.2.1.25 Bos taurus AAC48460.1
AAD39352.1
AAE16437.1
AAI47901.1
NP_776812.1		 Q29444
Q9TTG6		  
 Unknown (protein for MGC:155160)   Bos taurus AAI33416.1 A3KMY8  
 glycoside hydrolase family 2 protein (Bofut4_p088120.1)   Botryotinia fuckeliana CCD50749.1    
 glycoside hydrolase family 2 protein (Bofut4_p148680.1)   Botryotinia fuckeliana CCD56258.1    
 endo-β-mannosidase (Ebm) 3.2.1.152 Brassica oleracea BAE97370.1 Q14U56  
 C33G3.4   Caenorhabditis elegans Bristol N2 CAB01737.1
NP_510342.1		 Q93324  
 Y105E8B.n   Caenorhabditis elegans Bristol N2 CAB60857.2
CAC70111.1
NP_493548.1		 Q95Q32  
 CD36_27860   Candida dubliniensis CD36 CAX39789.1 B9WL84  
 CPAR2_801130   Candida parapsilosis CDC317 CCE41561.1    
 β-glucuronidase (GusB) 3.2.1.31 Canis lupus familiaris AAC48809.1 O18835.1  
 β-mannosidase 3.2.1.25 Capra hircus (MANBA) AAC48665.1 Q95327  
 β-glucuronidase (GusB) 3.2.1.31 Chlorocebus aethiops AAC34593.1 O77695.1  
 EGA (peptide fragment) (Gls2A)   Chrysosporium lucknowense      
 β-Gal (fragment)   Citrus medica CAP40294.1 A9J6N5  
 β-glucuronidase (GuS) (fragment)   Cynomys ludovicianus ABP87904.1 A4ZYQ9  
 ORF   Danio rerio AAH45360.1
AAH65988.1
NP_956453.1		 Q7ZVY7  
 CT573103.7-001 (probable fragment)   Danio rerio CAN88744.1 A5WW06  
 DEHA0E10021g   Debaryomyces hansenii CBS767 CAG87955.1    
 DEHA0G26345g   Debaryomyces hansenii CBS767 CAG91142.1    
 unknown   Dendroctonus ponderosae AEE63051.1    
 unknown   Dendroctonus ponderosae AEE61968.1    
 dd_03023   Dictyostelium discoideum AX4 AAM33758.1
AAO52199.1		 Q86A04  
 CG12582   Drosophila melanogaster AAF52171.2
AAF52172.2
AAN71636.1
AAX33506.1
NP_649436.2		 Q8IGB2
Q9VMY5		  
 CG2135   Drosophila melanogaster AAF57195.1
AAQ22542.1
NP_651893.1		 Q9V9T9  
 CG15117   Drosophila melanogaster AAF57602.2
AAL39474.1
AAM68434.1
AAS93746.1
AAX52695.1
ACV88434.1
NP_611395.1
NP_725851.1		 A1ZBG9  
 intracellular β-galactosidase BglD (BglD)   Emericella nidulans WG355 (Wageningen, NL) ADM36015.1    
 β-glucuronidase (fragment)   Equus caballus ABO86717.1 A4USH5  
 β-glucuronidase (GusB) 3.2.1.31 Felis catus AAD01498.1
AAD01499.1		 O97524.1  
 ORF   Fusarium oxysporum f. sp. fragariae BAD89519.1 Q5FBG0  
 ORF   Fusarium sp. IFO 7772 BAD89516.1 Q5FBG3  
 RCJMB04_28l23   Gallus gallus CAG32539.1 Q5ZIA4  
 ORF (fragment)   Gibberella fujikuroi BAD89523.2 Q5FBF6  
 ORF   Gibberella zeae F15 BAD89513.1 Q5FBG6  
 β-glucuronidase (BGLU) (fragment)   Gorilla gorilla AAL56230.1 Q8WNN2  
 ManA2   Gossypium barbadense ADZ16125.1    
 ManA2 (fragment)   Gossypium barbadense ADZ16124.1    
 ManA2   Gossypium herbaceum subsp. africanum ADZ16126.1    
 ORF   Gossypium hirsutum TM-1 AAK84953.2
AAO27794.1
ADZ16128.1
ADZ16129.1		 Q84XI2
Q93X75		  
 glycosyl hydrolase (Mana2)   Gossypium raimondii ADZ16127.1    
 β-glucuronidase b (GusB) 3.2.1.31 Homo sapiens AAA52561.1
AAH14142.1
AAQ96851.1
AAR75622.1
ABH92596.1
ACH09936.1
ACM86199.1
BAD97126.1
BAG35619.1
BAG61991.1
BAG64768.1
CAC41170.1
NP_000172.1		 P08236.2 1BHG[A,B]
3HN3[A,B,D,E]
 β-mannosidase (ManBA) 3.2.1.25 Homo sapiens AAC39573.1
AAH15743.1
ABS29701.1
BAD93083.1
BAF84287.1
BAG61830.1		 O00462.3  
 exo-β-glucosaminidase (Gls93) 3.2.1.165 Hypocrea jecorina PC-3-7 BAD99604.1 Q4R1C4 cryst
 β-mannosidase (5475) 3.2.1.25 Hypocrea jecorina Z12      
 exo-β-glucosaminidase (Gls1)   Hypocrea virens ACN62417.1 C0LRA7  
 β-galactosidase (Lac4;BgaL) 3.2.1.23 Kluyveromyces lactis CBS2359 AAA35265.1 P00723.2 3OB8[A,B,C,D]
3OBA[A,B,C,D]
 β-galactosidase (BgaL;KLLA0B14883g) 3.2.1.23 Kluyveromyces lactis NRRL Y-1140 CAH02587.1    
 β-galactosidase 3.2.1.23 Kluyveromyces marxianus DSM5418 AAS18310.1 Q6QTF4  
 ORF   Leptosphaeria maculans v23.1.3 CBX97149.1 E4ZZN3  
 ORF   Leptosphaeria maculans v23.1.3 CBX99479.1 E5A784  
 ORF   Leptosphaeria maculans v23.1.3 CBY01311.1 E5ADM2  
 ORF   Leptosphaeria maculans v23.1.3 CBY01568.1 E5AEC9  
 ORF (fragment)   Leptosphaeria maculans v23.1.3 CBX93875.1 E4ZRM8  
 ORF   Leptosphaeria maculans v23.1.3      
 ORF   Leptosphaeria maculans v23.1.3 CBX98985.1 E5A5U0  
 mannosylglycoprotein endo-β-mannosidase (Ebm) 3.2.1.152 Lilium longiflorum BAD89079.1
BAD89079.2		 Q5H7P5  
 β-glucuronidase (GUSB) (fragment)   Macaca mulatta AAV98539.1 Q4G3Z5  
 MG05890.4   Magnaporthe grisea 70-15 XP_369574.1    
 MG05864.4   Magnaporthe grisea 70-15 XP_369600.1    
 MG00583.4   Magnaporthe grisea 70-15 XP_368661.1    
 MG09664.4   Magnaporthe grisea 70-15 XP_364819.1 Q2KHA3  
 MG08964.4   Magnaporthe grisea 70-15 XP_364119.1    
 MG01178.4   Magnaporthe grisea 70-15 XP_363252.1    
 MtrDRAFT_AC151426g18v1 (possible fragment)   Medicago truncatula ABP03323.1    
 MICPUN_51444 (fragment)   Micromonas sp. RCC299 ACO68436.1 C1FDQ8  
 β-glucuronidase (GusB;Gus-S) 3.2.1.31 Mus musculus AAA37696.1
AAA37697.1
AAA63307.1
AAA63308.1
AAA63309.1
AAA98623.1
AAH71226.1
AAQ41980.1
BAE23021.1
BAE29265.1
BAE34865.1
BAE35155.1
BAE35384.1
BAE36917.1
CAC41171.1
NP_034498.1		 P12265.1  
 β-mannosidase 3.2.1.25 Mus musculus AAH31409.1
AAK18177.1
BAE24954.1
BAE38715.1
BAE41690.1
NP_081564.1		 Q8K2I4
Q99MS1		  
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99526.1    
 glucuronidase, beta, partial (fragment)   Mustela putorius furo AER99527.1    
 ORF (fragment)   Mustela putorius furo AES01514.1    
 MYCTH_90655   Myceliophthora thermophila ATCC 42464 AEO53082.1    
 MYCTH_2295445   Myceliophthora thermophila ATCC 42464 AEO53731.1    
 MYCTH_2094324   Myceliophthora thermophila ATCC 42464 AEO59187.1    
 MYCTH_2307767   Myceliophthora thermophila ATCC 42464 AEO59435.1    
 MYCTH_54601   Myceliophthora thermophila ATCC 42464 AEO60310.1    
 MYCTH_114497   Myceliophthora thermophila ATCC 42464 AEO54508.1    
 MYCTH_40111 (fragment)   Myceliophthora thermophila ATCC 42464 AEO55648.1    
 lysosomal β-glucuronidase (fragment)   Mytilus galloprovincialis ABY60966.1 B0FN51  
 NCU00985.1 (B20J13.350)   Neurospora crassa OR74A CAE76354.1
XP_325165.1		 Q7SGD7  
 NCU05956.1   Neurospora crassa OR74A XP_325811.1    
 NCU00810.1   Neurospora crassa OR74A XP_324990.1    
 NCU09042.1   Neurospora crassa OR74A XP_331434.1    
 NCU00890.1   Neurospora crassa OR74A XP_325070.1    
 Os01g0952600   Oryza sativa Japonica Group BAB64698.1
BAD87855.1
BAF07335.1
NP_914661.1		 Q5JKZ9  
 Os05g0391500   Oryza sativa Japonica Group AAV31255.1
BAF17358.1		 Q0DIG5  
 OSTLU_119488   Ostreococcus lucimarinus CCE9901 ABO94678.1 A4RT31  
 Ot07g03490   Ostreococcus tauri OTTH0595 CAL54622.1 Q014Q7  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens DSM1215 AAV91787.1 Q5MJY0  
 β-glucuronidase (Gus) 3.2.1.31 Penicillium canescens RPK AAV91785.1 Q5MJY2  
 Pc12g11750   Penicillium chrysogenum Wisconsin 54-1255 CAP80802.1 B6GXQ4  
 Pc12g13420   Penicillium chrysogenum Wisconsin 54-1255 CAP80969.1 B6GZU1  
 Pc16g06840   Penicillium chrysogenum Wisconsin 54-1255 CAP93354.1
CAV33708.1		 B6H7F7  
 Pc16g06900   Penicillium chrysogenum Wisconsin 54-1255 CAP93360.1 B6H7G3  
 Pc21g13810   Penicillium chrysogenum Wisconsin 54-1255 CAP96278.1
CAV33710.1		 B6HNQ6  
 Pc22g14540   Penicillium chrysogenum Wisconsin 54-1255 CAP98742.1 B6HUZ1  
 β-glucuronidase (PguS) 3.2.1.31 Penicillium purpurogenum LI-3 ABU68712.1 A7XS03  
 WS02759_M23 (fragment)   Picea sitchensis ABR16858.1 B8LMH8  
 PICST_30036   Pichia stipitis CBS 6054 ABN64540.1
ABN64540.2		    
 PICST_43820   Pichia stipitis CBS 6054 ABN65300.1
ABN65300.2		    
 PIIN_00917   Piriformospora indica CCA67082.1    
 PIIN_01338   Piriformospora indica CCA67509.1    
 unnamed protein product   Podospora anserina S mat+ CAP59820.1 B2A9R0  
 unnamed protein product   Podospora anserina S mat+ CAP60205.1 B2AAU3  
 unnamed protein product   Podospora anserina S mat+ CAP61774.1 B2AEA8  
 Pa_5_10470   Podospora anserina S mat+ CAP65831.1 B2APB4  
 unnamed protein product   Podospora anserina S mat+ CAP66718.1 B2ARE0  
 unnamed protein product   Podospora anserina S mat+ CAP67962.1 B2AU89  
 unnamed protein product   Podospora anserina S mat+ CAP70161.1 B2AZW1  
 DKFZp468F089   Pongo abelii CAH91050.1 Q5RB10  
 DKFZp459E0319   Pongo abelii CAH92009.1 Q5R5N6  
 DKFZp469C0414   Pongo abelii CAH92930.1 Q5R5N6  
 DKFZp468F187   Pongo abelii CAH90241.1 Q5RDB6  
 β-glucuronidase (BGLU) (fragment)   Pongo pygmaeus AAL56231.1 Q8WNN1  
 Unknown (protein for MGC:116230)   Rattus norvegicus AAH99094.1
AAI11711.1		 Q4FZV0  
 β-glucuronidase (GusB;Gus) 3.2.1.31 Rattus norvegicus AAA41228.1
AAP86274.1
CAA68705.1
NP_058711.1		 P06760.1
Q7TPJ3		  
 SJCHGC07237 (fragment)   Schistosoma japonicum AAX25842.2 Q5C3D3  
 Smp_137150   Schistosoma mansoni CAZ30440.1
CCD79187.1		 C4Q4Q9  
 β-glucuronidase (Gus) 3.2.1.31 Scopulariopsis sp. RP38.3 AAV91788.1 Q5MJX9  
 sr13138   Sporisorium reilianum SRZ2 CBQ72430.1    
 β-glucuronidase (GusB)   Sus scrofa AAZ03639.1 Q4FAT7  
 THITE_2110051   Thielavia terrestris NRRL 8126 AEO64183.1    
 THITE_2110638   Thielavia terrestris NRRL 8126 AEO64472.1    
 THITE_2112614   Thielavia terrestris NRRL 8126 AEO65527.1    
 THITE_2046339   Thielavia terrestris NRRL 8126 AEO66261.1    
 THITE_2049779   Thielavia terrestris NRRL 8126 AEO67616.1    
 THITE_2120695   Thielavia terrestris NRRL 8126 AEO69937.1    
 THITE_124733   Thielavia terrestris NRRL 8126 AEO71826.1    
 THITE_2109377 (fragment)   Thielavia terrestris NRRL 8126 AEO63777.1    
 β-galactosidase   Trichomonas vaginalis ABL07608.1 A1E4C9  
 VITISV_002311   Vitis vinifera CAN82620.1 A5AVM0  
 Unknown (protein for MGC:82825)   Xenopus laevis AAH78052.1 Q6DCI1  




Last update: 2012-01-31 © Copyright 1998-2012
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