Glycoside Hydrolase Family 2

Activities in Familyβ-galactosidase (EC 3.2.1.23) ; β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); α-L-arabinofuranosidase (EC 3.2.1.55); mannosylglycoprotein endo-β-mannosidase (EC 3.2.1.152); exo-β-glucosaminidase (EC 3.2.1.165); α-L-arabinopyranosidase (EC 3.2.1.-); β-galacturonidase (EC 3.2.1.-); β-xylosidase (EC 3.2.1.37); β-D-galactofuranosidase (EC 3.2.1.146); β-glucosidase (EC 3.2.1.21)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (23444); Uniprot accession (1654); PDB accession (204); 3D entries (52); cryst (2)
All (22115) Archaea (80) Bacteria (21479) Eukaryota (523) unclassified (33) Structure (52 - 2 cryst) Characterized (179)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Cmaq_1386   Caldivirga maquilingensis IC-167 ABW02212.1 A8M8Z3  
 DSAG12_02537   Candidatus Prometheoarchaeum syntrophicum MK-D1 QEE16707.1    
 DSAG12_00871   Candidatus Prometheoarchaeum syntrophicum MK-D1 QEE15048.1    
 DSAG12_02347   Candidatus Prometheoarchaeum syntrophicum MK-D1 QEE16517.1    
 DSAG12_01762   Candidatus Prometheoarchaeum syntrophicum MK-D1 QEE15935.1    
 HacjB3_16721   Halalkalicoccus jeotgali B3 ADJ16694.1 D8JBP1  
 HacjB3_16966   Halalkalicoccus jeotgali B3 ADJ16743.1 D8JBU0  
 HacjB3_16966   Halalkalicoccus jeotgali B3 ADJ16743.1 D8JBU0  
 EFA46_011175 (fragment)   Halarchaeum sp. CBA1220 QLC34818.1    
 G9465_22090   Haloarcula sp. JP-L23 QIO24993.1    
 HARCEL1_10595   Haloarculaceae archaeon HArcel1 AWB28121.1    
 HUG10_15755   Halobonum sp. Gai3-2 QLG28908.1    
 HUG10_09675   Halobonum sp. Gai3-2 QLG27803.1    
 HUG10_16330   Halobonum sp. Gai3-2 QLG29008.1    
 HUG10_16330   Halobonum sp. Gai3-2 QLG29008.1    
 ABY42_16825 (fragment)   Haloferax gibbonsii ARA6 AKU09508.1    
 Hmuk_3226   Halomicrobium mukohataei DSM 12286 ACV49329.1 C7P4T4  
 LC1Hm_1176 (Lacz2)   Halomicrobium sp. LC1Hm QGA82233.1    
 LC1Hm_0425 (LacZ)   Halomicrobium sp. LC1Hm QGA81489.1    
 LC1Hm_4132 (LacZ)   Halomicrobium sp. LC1Hm QGA84464.1    
 E5139_16015   Halomicrobium sp. ZP60 QCD67168.1    
 Halxa_0469   Halopiger xanaduensis SH-6 AEH39070.1    
 Halxa_3986   Halopiger xanaduensis SH-6 AEH38591.1    
 Halxa_0517   Halopiger xanaduensis SH-6 AEH39116.1    
 Hrd1104_06780   Halorhabdus sp. CBA1104 QGN07028.1    
 HTIA_1885   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ34004.1    
 HTIA_2226   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ34337.1    
 HTIA_1067   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33205.1    
 Huta_2842   Halorhabdus utahensis DSM 12940 ACV13003.1 C7NR78  
 Huta_2111   Halorhabdus utahensis DSM 12940 ACV12278.1 C7NU33  
 Huta_2440   Halorhabdus utahensis DSM 12940 ACV12606.1 C7NMG7  
 HZS54_24185   Halosimplex pelagicum R2 QLH84550.1    
 HZS54_19505   Halosimplex pelagicum R2 QLH83682.1    
 HZS54_13960   Halosimplex pelagicum R2 QLH82658.1    
 HZS54_16360   Halosimplex pelagicum R2 QLH83100.1    
 HZS55_16690   Halosimplex rubrum R27 QLH78826.1    
 HZS55_20715   Halosimplex rubrum R27 QLH79565.1    
 HZS55_14530   Halosimplex rubrum R27 QLH80013.1    
 HZS55_14505   Halosimplex rubrum R27 QLH78432.1    
 HZS55_12505   Halosimplex rubrum R27 QLH78071.1    
 HZS55_14520   Halosimplex rubrum R27 QLH78435.1    
 HZS55_14515   Halosimplex rubrum R27 QLH78434.1    
 HALLA_03270   Halostagnicola larsenii XH-48 AHG01421.1    
 HALLA_04610   Halostagnicola larsenii XH-48 AHG01687.1    
 HALLA_21085   Halostagnicola larsenii XH-48 AHG02402.1    
 HALLA_01275   Halostagnicola larsenii XH-48 AHG01958.1    
 HALLA_01275   Halostagnicola larsenii XH-48 AHG01958.1    
 HYG82_17150   Haloterrigena sp. YPL8 QLG50451.1    
 HYG82_04175   Haloterrigena sp. YPL8 QLG48099.1    
 Htur_4671   Haloterrigena turkmenica DSM 5511 ADB63454.1 D2S257  
 Htur_3122   Haloterrigena turkmenica DSM 5511 ADB61987.1 D2RZ19  
 Htur_3896   Haloterrigena turkmenica DSM 5511 ADB62754.1 D2S057  
 Htur_3903   Haloterrigena turkmenica DSM 5511 ADB62761.1 D2S064  
 Htur_4208   Haloterrigena turkmenica DSM 5511 ADB63029.1 D2S0Y2  
 Htur_4492   Haloterrigena turkmenica DSM 5511 ADB63303.1 D2S1Q6  
 Htur_3909   Haloterrigena turkmenica DSM 5511 ADB62765.1 D2S068  
 Htur_3909   Haloterrigena turkmenica DSM 5511 ADB62765.1 D2S068  
 Igag_0371   Ignisphaera aggregans DSM 17230 ADM27213.1 E0SR64  
 HYG81_17960   Natrinema sp. YPL30 YPL13 QLK25936.1    
 HYG81_17960   Natrinema sp. YPL30 YPL13 QLK25936.1    
 GCU68_19945   Natronorubrum aibiense 7-3 QFU84781.1    
 GCU68_19970   Natronorubrum aibiense 7-3 QFU84786.1    
 β-glucuronidase (GusB;Ssol98_010100007956) 3.2.1.31 Saccharolobus solfataricus 98/2 AET42956.1    
 SULC_0815   Saccharolobus solfataricus 98/2 SULC AKA75879.1    
 SSOP1_3131   Saccharolobus solfataricus P1 SAI86685.1    
 SSO3036 (GusB)   Saccharolobus solfataricus P2 AAK43138.1
NP_344348.1
Q97UI1  
 SULZ_04210   Saccharolobus solfataricus SUL120 AZF83365.1    
 SULA_0815   Saccharolobus solfataricus SULA AKA78571.1    
 SULB_0817   Saccharolobus solfataricus SULB AKA73181.1    
 L593_05990   Salinarchaeum sp. Harcht-Bsk1 AGN01147.1    
 HS1genome_1664   Sulfodiicoccus acidiphilus HS-1 BBD73275.1    
 SiH_2259   Sulfolobus islandicus HVE10/4 ADX83600.1    
 LD85_2610   Sulfolobus islandicus L.D.8.5 ADB88228.1 D2PFW2  
 LS215_2491   Sulfolobus islandicus L.S.2.15 ACP36452.1 C3ML50  
 SiL_2168   Sulfolobus islandicus LAL14/1 AGJ63609.1    
 M1425_2319   Sulfolobus islandicus M.14.25 ACP39050.1 C3MSA7  
 M1627_2398   Sulfolobus islandicus M.16.27 ACP56255.1 C3N1M8  
 M164_2321   Sulfolobus islandicus M.16.4 ACR42920.1 C4KKQ8  
 SiRe_2206   Sulfolobus islandicus REY15A ADX86260.1    
 YG5714_2459   Sulfolobus islandicus Y.G.57.14 ACP46701.1 C3NAA8  
 YN1551_0450   Sulfolobus islandicus Y.N.15.51 ACP47611.1 C3NL97  
 GFS03_12495   Sulfolobus sp. E5-1-F QGA55331.1    
 GZ1D1_24 (LacZ)   uncultured archaeon GZfos1D1 AAU82837.1 Q64CP0  
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