Glycoside Hydrolase Family 27

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1384); Uniprot accession (327); PDB accession (46); 3D entries (13); cryst (0)
All (1128) Archaea (1) Bacteria (797) Eukaryota (329) unclassified (1) Structure (13) Characterized (66)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SIRAN8581   Streptomyces iranensis CDR15103.1    
 SIRAN764   Streptomyces iranensis CDR02424.1    
 SIRAN2834   Streptomyces iranensis CDR05905.1    
 Sle_08850   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60348.1    
 SLINC_0473   Streptomyces lincolnensis NRRL 2936 ANS62697.1    
 SLINC_8276   Streptomyces lincolnensis NRRL 2936 ANS70500.1    
 SLIV_36495   Streptomyces lividans TK24 AIJ18174.1    
 SL103_13360   Streptomyces lydicus 103 AOP47112.1    
 SL103_12745   Streptomyces lydicus 103 AOP51157.1    
 BBN63_04780   Streptomyces niveus SCSIO 3406 AQU70669.1    
 SNOD_01840   Streptomyces nodosus ATCC 14899 AJE38935.1    
 SNOUR_34065   Streptomyces noursei ATCC 11455 ANZ20044.1    
 B1H29_32855   Streptomyces pactum ACT12 AQS71042.1    
 BFF78_40730   Streptomyces puniciscabiei TW1S1 AOR36551.1    
 BFF78_05130   Streptomyces puniciscabiei TW1S1 AOR30518.1    
 BFF78_37940   Streptomyces puniciscabiei TW1S1 AOR37584.1    
 M271_02455   Streptomyces rapamycinicus NRRL 5491 AGP52124.1    
 M271_03595   Streptomyces rapamycinicus NRRL 5491 AGP52349.1    
 M271_06760   Streptomyces rapamycinicus NRRL 5491 AGP52976.1    
 M271_14475   Streptomyces rapamycinicus NRRL 5491 AGP54483.1    
 M271_43050   Streptomyces rapamycinicus NRRL 5491 AGP59984.1    
 M271_32050   Streptomyces rapamycinicus NRRL 5491 AGP57836.1    
 TUE45_06955 (Agaa_3)   Streptomyces reticuli CUW32206.1    
 TUE45_06393 (Agaa_2)   Streptomyces reticuli CUW31645.1    
 TUE45_01426 (Agaa_1)   Streptomyces reticuli CUW26714.1    
 SCAB_3891   Streptomyces scabiei 87.22 CBG67596.1 C9YSS1  
 SCAB_44311   Streptomyces scabiei 87.22 CBG71494.1 C9Z7A0  
 A7J05_30895   Streptomyces silaceus ACCC40021 APY89513.1    
 CGL27_41880   Streptomyces sp. 11-1-2 ASR00662.1    
 CGL27_43610   Streptomyces sp. 11-1-2 ASQ98986.1    
 CGL27_34505   Streptomyces sp. 11-1-2 ASQ97466.1    
 CGL27_01315 (fragment)   Streptomyces sp. 11-1-2 ASQ91987.1    
 CGL27_17765   Streptomyces sp. 11-1-2 ASQ94669.1    
 CGL27_46485   Streptomyces sp. 11-1-2 ASQ99481.1    
 SAMN05428941_0341   Streptomyces sp. 2114.2 SDS35916.1    
 SAMN06272775_6259   Streptomyces sp. 2323.1 SOE15337.1    
 SAMN06272775_6123   Streptomyces sp. 2323.1 SOE15193.1    
 SAMN05444521_0734   Streptomyces sp. 3124.6 SHH50113.1    
 SAMN05444521_0934   Streptomyces sp. 3124.6 SHH56056.1    
 SAMN05444521_5974   Streptomyces sp. 3124.6 SHI23977.1    
 SAMN05444521_7950   Streptomyces sp. 3124.6 SHI58199.1    
 GZL_07409   Streptomyces sp. 769 AJC59961.1    
 T261_6922   Streptomyces sp. A02 AJT68524.2
AJT68524.1
   
 T261_7147   Streptomyces sp. A02 AJT68749.1    
 NI25_34100   Streptomyces sp. CCM_MD2014 AIV37935.1    
 AS200_10420   Streptomyces sp. CdTB01 ALV32406.1    
 AS200_40885   Streptomyces sp. CdTB01 ALV37727.1    
 AS200_38445   Streptomyces sp. CdTB01 ALV38988.1    
 AS200_04770   Streptomyces sp. CdTB01 ALV38369.1    
 AA958_01970   Streptomyces sp. CNQ-509 AKH81139.1    
 AA958_29905   Streptomyces sp. CNQ-509 AKH85740.1    
 B1K54_31000   Streptomyces sp. fd1-xmd AQT76935.1    
 M444_06680   Streptomyces sp. Mg1 AKL69829.1    
 STRMOE7_07355   Streptomyces sp. MOE7 ARH95140.1    
 STRMOE7_06640   Streptomyces sp. MOE7 ARH90028.1    
 QR97_19620   Streptomyces sp. PBH53 AKN71716.1    
 QR97_23530   Streptomyces sp. PBH53 AKN72345.1    
 QR97_32570   Streptomyces sp. PBH53 AKN73833.1    
 A4E84_21635   Streptomyces sp. S10(2016) AMW11872.1    
 B6R96_05975   Streptomyces sp. Sge12 ARE78787.1    
 SACTE_6011   Streptomyces sp. SirexAA-E AEN13791.1    
 SAMN05216371_1142   Streptomyces sp. TLI_053 SDT03378.1    
 SAMN05216371_1141   Streptomyces sp. TLI_053 SDT03332.1    
 BSL84_28910   Streptomyces sp. TN58 APU44770.1    
 SVTN_36345   Streptomyces vietnamensis GIM4.0001 AJF70206.1    
 Strvi_2248   Streptomyces violaceusniger Tu 4113 AEM81975.1    
 Strvi_3740   Streptomyces violaceusniger Tu 4113 AEM83404.1    
 Strvi_4333   Streptomyces violaceusniger Tu 4113 AEM83982.1    
 Strvi_5822   Streptomyces violaceusniger Tu 4113 AEM85332.1    
 Strvi_7924   Streptomyces violaceusniger Tu 4113 AEM87247.1    
 TERTU_4091   Teredinibacter turnerae T7901 ACR13989.1 C5BUE6  
 Terro_1771   Terriglobus roseus DSM 18391 AFL88067.1    
 Terro_4303   Terriglobus roseus DSM 18391 AFL90500.1    
 SAMN05444167_2796   Terriglobus roseus GAS232 SDF60734.1    
 SAMN05444167_3716   Terriglobus roseus GAS232 SDF92564.1    
 SAMN05444167_0756   Terriglobus roseus GAS232 SDE89736.1    
 AciPR4_1545   Terriglobus saanensis SP1PR4 ADV82366.1 E1N696  
 AciPR4_1700   Terriglobus saanensis SP1PR4 ADV82507.1 E1MXY3  
 AciPR4_4094   Terriglobus saanensis SP1PR4 ADV84842.1 E1MZ30  
 THTE_2109   Thermogutta terrifontis R1 ASV74711.1    
 melibiase, partial (fragment)   uncultured bacterium AMJ34093.1    
 ORF (fragment)   uncultured bacterium AMJ33835.1    
 Unknown Function, partial (fragment)   uncultured bacterium APO29964.1    
 GH27   uncultured bacterium AQQ75132.1    
 α-galactosidase (GHF31)   uncultured bacterium AGG23327.1    
 ORF (fragment)   uncultured bacterium AIA19270.1    
 α-galactosidase   uncultured bacterium AZ_40 AKA59483.1    
 ORF   uncultured bacterium Contig13 AHF24669.1    
 ORF   uncultured bacterium G2_7 AEW47968.1    
 SPPYR_0566   uncultured Sphingopyxis sp. SBV31686.1    
 CMV30_05145   Verrucomicrobia bacterium HZ-65 ATC63388.1    
 CMV30_15700 (fragment)   Verrucomicrobia bacterium HZ-65 ATC66187.1    
 IMCC26134_08915   Verrucomicrobia bacterium IMCC26134 AKC82865.1    
 VAB18032_19530   Verrucosispora maris AB-18-032 AEB45008.1    
 BME96_15605   Virgibacillus halodenitrificans PDB-F2 APC49532.1    
 XALc_1947   Xanthomonas albilineans GPE PC73 CBA16433.1    
 zobellia_3523   Zobellia galactanivorans DsiJT CAZ97661.1    
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