Glycoside Hydrolase Family 27

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1562); Uniprot accession (327); PDB accession (47); 3D entries (14); cryst (0)
All (1305) Archaea (1) Bacteria (955) Eukaryota (347) Viruses (1) unclassified (1) Structure (14) Characterized (69)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AOU00_24210   Paenibacillus polymyxa J AOK92664.1    
 PPM_2208 (M1_2499)   Paenibacillus polymyxa M1 CCC85145.1    
 RE92_00805   Paenibacillus polymyxa Sb3-1 AJE49682.1    
 PPSC2_c2450   Paenibacillus polymyxa SC2 ADO56422.1 E3EJD5  
 PPSQR21_022940   Paenibacillus polymyxa SQR-21 SQR21 AHM65939.1    
 PRIO_5005   Paenibacillus riograndensis SBR5 CQR57407.1    
 PRIO_2637   Paenibacillus riograndensis SBR5 CQR55041.1    
 PRIO_1726   Paenibacillus riograndensis SBR5 CQR54109.1    
 PSAB_19400   Paenibacillus sabinae T27 AHV98773.1    
 BBD42_23010   Paenibacillus sp. BIHB4019 ANY69031.1    
 BBD42_17810   Paenibacillus sp. BIHB4019 ANY70802.1    
 DCC85_01765   Paenibacillus sp. CAA11 AWB43082.1    
 H70357_33375   Paenibacillus sp. FSL H7-0357 AIQ21024.1    
 H70737_07485   Paenibacillus sp. FSL H7-0737 AIQ22709.1    
 P40081_13505   Paenibacillus sp. FSL P4-0081 AIQ29066.1    
 P40081_08255   Paenibacillus sp. FSL P4-0081 AIQ28174.1    
 R50345_07770   Paenibacillus sp. FSL R5-0345 AIQ34519.1    
 R50912_07385   Paenibacillus sp. FSL R5-0912 AIQ39871.1    
 R50912_13110   Paenibacillus sp. FSL R5-0912 AIQ40862.1    
 R70723_12535   Paenibacillus sp. FSL R7-0273 AIQ46608.1    
 R70723_08015   Paenibacillus sp. FSL R7-0273 AIQ45829.1    
 R70331_08060   Paenibacillus sp. FSL R7-0331 AIQ51467.1    
 R70331_11980   Paenibacillus sp. FSL R7-0331 AIQ52152.1    
 ASL14_24610   Paenibacillus sp. IHB B 3084 ALP38859.1    
 Pjdr2_3202   Paenibacillus sp. JDR-2 ACT01843.1 C6D1H9  
 Pjdr2_3562   Paenibacillus sp. JDR-2 ACT02195.1 C6D3K2  
 Pjdr2_4264   Paenibacillus sp. JDR-2 ACT02888.1 C6D785  
 Pjdr2_4104   Paenibacillus sp. JDR-2 ACT02733.1 C6D6G0  
 C0638_21560   Paenibacillus sp. lzh-N1 AUO08933.1    
 HPL003_22715   Paenibacillus terrae HPL-003 AET61267.1    
 BS614_18535   Paenibacillus xylanexedens PAMC 22703 APO45824.1    
 BS614_07785   Paenibacillus xylanexedens PAMC 22703 APO43919.1    
 Palpr_1630   Paludibacter propionicigenes WB4 ADQ79771.1 E4T4X7  
 Palpr_1653   Paludibacter propionicigenes WB4 ADQ79794.1 E4T500  
 Palpr_1815   Paludibacter propionicigenes WB4 ADQ79954.1 E4T5G0  
 Palpr_1626   Paludibacter propionicigenes WB4 ADQ79767.1 E4T4X3  
 CI960_12085   Parabacteroides sp. CT06 AST54032.1    
 K788_0002948 (fragment)   Paraburkholderia caribensis MBA4 ALL66697.1    
 C2L64_46520   Paraburkholderia hospita DSM 17164 AUT76140.1    
 C2L64_51555 (fragment)   Paraburkholderia hospita DSM 17164 AUT76582.1    
 AY601_0610   Pedobacter cryoconitis PAMC 27485 AMP97560.1    
 CPT03_12235   Pedobacter ginsengisoli T01R-27 ATP57186.1    
 Phep_0715   Pedobacter heparinus DSM 2366 ACU02937.1 C6Y1G1  
 Phep_1839   Pedobacter heparinus DSM 2366 ACU04047.1 C6XVI1  
 Phep_2885   Pedobacter heparinus DSM 2366 ACU05083.1 C6Y1U1  
 Phep_2887   Pedobacter heparinus DSM 2366 ACU05085.1 C6Y1U3  
 AQ505_17305   Pedobacter sp. PACM 27299 ALL08859.1    
 AQ505_11245   Pedobacter sp. PACM 27299 ALL06016.1    
 BFS30_21025   Pedobacter steynii DX4 AOM79427.1    
 PSMK_08660   Phycisphaera mikurensis NBRC 102666 BAM03025.1    
 L21SP3_02304 (AgaA)   Phycisphaerae bacterium L21-RPul-D3 AQQ10471.1    
 STSP2_00372 (Agaa_1)   Phycisphaerae bacterium ST-NAGAB-D1 AQT67229.1    
 STSP2_02148 (Agaa_2)   Phycisphaerae bacterium ST-NAGAB-D1 AQT68970.1    
 STSP2_02617 (Agaa_3)   Phycisphaerae bacterium ST-NAGAB-D1 AQT69427.1    
 STSP1_01036 (AgaA)   Phycisphaerae bacterium ST-PulAB-D4 ARN56648.1    
 C6W10_17535 (fragment)   Plantactinospora sp. BB1 AVT41574.1    
 C6W10_18085   Plantactinospora sp. BB1 AVT38034.1    
 C6361_22580 (fragment)   Plantactinospora sp. BC1 AVT34709.1    
 C6361_28840   Plantactinospora sp. BC1 AVT32805.1    
 C6361_01335   Plantactinospora sp. BC1 AVT28359.1    
 BWO91_09610   Plantibacter flavus 251 AQX82132.1    
 CW731_00480   Polaribacter sp. ALD11 AUC83853.1    
 CW731_00370   Polaribacter sp. ALD11 AUC83833.1    
 LPB03_10260   Polaribacter vadi LPB0003 AOW17813.1    
 α-galactosidase (AgaA)   Pontibacter sp. HJ8 AME17654.1    
 PGF_00020000   Porphyromonas gingivalis 381 ALJ26412.1    
 PGA7_00000800   Porphyromonas gingivalis A7436 AKV63328.1    
 PGS_00019270   Porphyromonas gingivalis A7A1-28 ALO30584.1    
 PGJ_00000730   Porphyromonas gingivalis AJW4 ALA92716.1    
 PGN_2032   Porphyromonas gingivalis ATCC 33277 BAG34550.1
AUR49317.1
B2RMF5  
 EG14_01910   Porphyromonas gingivalis HG66 AIJ34887.1    
 CS059_03780   Porphyromonas gingivalis KCOM 2796 ATS02196.1    
 CS374_04770   Porphyromonas gingivalis KCOM 2798 ATS04365.1    
 CS387_07250   Porphyromonas gingivalis KCOM 2799 ATS06777.1    
 CS388_05270   Porphyromonas gingivalis KCOM 2800 ATS08483.1    
 CS543_01865   Porphyromonas gingivalis KCOM 2801 ATS09734.1    
 CS544_06160   Porphyromonas gingivalis KCOM 2802 ATR90698.1    
 CS545_00110   Porphyromonas gingivalis KCOM 2803 ATR91632.1    
 CS546_06405   Porphyromonas gingivalis KCOM 2804 ATR94682.1    
 CS548_01525   Porphyromonas gingivalis KCOM 2805 ATR95878.1    
 CS550_09660   Porphyromonas gingivalis KCOM 3001 ATR99387.1    
 CS549_04565   Porphyromonas gingivalis KCOM 3131 ATS00409.1    
 CF002_0363 (MelA)   Porphyromonas gingivalis TDC 60 AUR47560.1    
 PGTDC60_0363   Porphyromonas gingivalis TDC60 BAK24532.1    
 CF003_0085 (MelA)   Porphyromonas gingivalis W83 AUR45827.1    
 PG0085   Porphyromonas gingivalis W83 AAQ65333.1
NP_904434.1
Q7MXS5  
 Prede_1403   Prevotella dentalis DSM 3688 AGB28718.1    
 HMPREF9137_0438   Prevotella denticola F0289 AEA20682.1    
 ADJ77_07260   Prevotella fusca JCM 17724 AKU69569.1    
 CRM71_07595   Prevotella jejuni CD3_33 AUI55170.1    
 CRM71_07730   Prevotella jejuni CD3_33 AUI55194.1    
 HMPREF0659_A6322   Prevotella melaninogenica ATCC 25845 ADK96067.1 D9RSZ1  
 ADK96222.1   Prevotella melaninogenica ATCC 25845 ADK96222.1    
 CEP85_06955   Prevotella melaninogenica FDAARGOS_306 ASE17827.1    
 CEP85_06700   Prevotella melaninogenica FDAARGOS_306 ASE17782.1    
 PMEL1_01319   Prevotella melaninogenica GAI 07411 BBA29384.1    
 PMEL1_01281   Prevotella melaninogenica GAI 07411 BBA29349.1    
 PRU_2377   Prevotella ruminicola 23 ADE82935.1 D5EVX6  
 HMPREF9420_1550   Prevotella salivae DSM 15606 EFV04299.1    
 AXF22_02475   Prevotella scopos JCM 17725 ANR72383.1    
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