Glycoside Hydrolase Family 27

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1483); Uniprot accession (327); PDB accession (46); 3D entries (13); cryst (0)
All (1225) Archaea (1) Bacteria (879) Eukaryota (343) Viruses (1) unclassified (1) Structure (13) Characterized (68)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AQ505_11245   Pedobacter sp. PACM 27299 ALL06016.1    
 BFS30_21025   Pedobacter steynii DX4 AOM79427.1    
 PSMK_08660   Phycisphaera mikurensis NBRC 102666 BAM03025.1    
 L21SP3_02304 (AgaA)   Phycisphaerae bacterium L21-RPul-D3 AQQ10471.1    
 STSP2_00372 (Agaa_1)   Phycisphaerae bacterium ST-NAGAB-D1 AQT67229.1    
 STSP2_02148 (Agaa_2)   Phycisphaerae bacterium ST-NAGAB-D1 AQT68970.1    
 STSP2_02617 (Agaa_3)   Phycisphaerae bacterium ST-NAGAB-D1 AQT69427.1    
 STSP1_01036 (AgaA)   Phycisphaerae bacterium ST-PulAB-D4 ARN56648.1    
 BWO91_09610   Plantibacter flavus 251 AQX82132.1    
 CW731_00480   Polaribacter sp. ALD11 AUC83853.1    
 CW731_00370   Polaribacter sp. ALD11 AUC83833.1    
 LPB03_10260   Polaribacter vadi LPB0003 AOW17813.1    
 α-galactosidase (AgaA)   Pontibacter sp. HJ8 AME17654.1    
 PGF_00020000   Porphyromonas gingivalis 381 ALJ26412.1    
 PGA7_00000800   Porphyromonas gingivalis A7436 AKV63328.1    
 PGS_00019270   Porphyromonas gingivalis A7A1-28 ALO30584.1    
 PGJ_00000730   Porphyromonas gingivalis AJW4 ALA92716.1    
 PGN_2032   Porphyromonas gingivalis ATCC 33277 BAG34550.1
AUR49317.1
B2RMF5  
 EG14_01910   Porphyromonas gingivalis HG66 AIJ34887.1    
 CS059_03780   Porphyromonas gingivalis KCOM 2796 ATS02196.1    
 CS374_04770   Porphyromonas gingivalis KCOM 2798 ATS04365.1    
 CS387_07250   Porphyromonas gingivalis KCOM 2799 ATS06777.1    
 CS388_05270   Porphyromonas gingivalis KCOM 2800 ATS08483.1    
 CS543_01865   Porphyromonas gingivalis KCOM 2801 ATS09734.1    
 CS544_06160   Porphyromonas gingivalis KCOM 2802 ATR90698.1    
 CS545_00110   Porphyromonas gingivalis KCOM 2803 ATR91632.1    
 CS546_06405   Porphyromonas gingivalis KCOM 2804 ATR94682.1    
 CS548_01525   Porphyromonas gingivalis KCOM 2805 ATR95878.1    
 CS550_09660   Porphyromonas gingivalis KCOM 3001 ATR99387.1    
 CS549_04565   Porphyromonas gingivalis KCOM 3131 ATS00409.1    
 CF002_0363 (MelA)   Porphyromonas gingivalis TDC 60 AUR47560.1    
 PGTDC60_0363   Porphyromonas gingivalis TDC60 BAK24532.1    
 CF003_0085 (MelA)   Porphyromonas gingivalis W83 AUR45827.1    
 PG0085   Porphyromonas gingivalis W83 AAQ65333.1
NP_904434.1
Q7MXS5  
 Prede_1403   Prevotella dentalis DSM 3688 AGB28718.1    
 HMPREF9137_0438   Prevotella denticola F0289 AEA20682.1    
 ADJ77_07260   Prevotella fusca JCM 17724 AKU69569.1    
 CRM71_07595   Prevotella jejuni CD3_33 AUI55170.1    
 CRM71_07730   Prevotella jejuni CD3_33 AUI55194.1    
 HMPREF0659_A6322   Prevotella melaninogenica ATCC 25845 ADK96067.1 D9RSZ1  
 ADK96222.1   Prevotella melaninogenica ATCC 25845 ADK96222.1    
 CEP85_06955   Prevotella melaninogenica FDAARGOS_306 ASE17827.1    
 CEP85_06700   Prevotella melaninogenica FDAARGOS_306 ASE17782.1    
 PMEL1_01319   Prevotella melaninogenica GAI 07411 BBA29384.1    
 PMEL1_01281   Prevotella melaninogenica GAI 07411 BBA29349.1    
 PRU_2377   Prevotella ruminicola 23 ADE82935.1 D5EVX6  
 HMPREF9420_1550   Prevotella salivae DSM 15606 EFV04299.1    
 AXF22_02475   Prevotella scopos JCM 17725 ANR72383.1    
 AXF22_02200   Prevotella scopos JCM 17725 ANR72335.1    
 HMPREF0669_01846   Prevotella sp. oral taxon 299 str. F0039 EFC70149.2    
 Achl_0056   Pseudarthrobacter chlorophenolicus A6 ACL38059.1 B8H885  
 SAMN04489743_0354   Pseudarthrobacter equi IMMIB L-1606 SDS56950.1    
 Pedsa_2573   Pseudopedobacter saltans DSM 12145 ADY53117.1    
 Pedsa_3616   Pseudopedobacter saltans DSM 12145 ADY54145.1    
 B1209_27615   Raoultella planticola GODA AUV56146.1    
 BTZ20_3734   Rhodococcus sp. MTM3W5.2 AQA24889.1    
 Rmar_2597   Rhodothermus marinus DSM 4252 ACY49470.1 D0MFY1  
 Rhom172_2613   Rhodothermus marinus SG0.5JP17-172 AEN74501.1    
 RHOM_06015   Roseburia hominis A2-183 AEN96322.1    
 ROI_10050   Roseburia intestinalis M50/1 CBL08208.1 D4KMV6  
 RO1_22250   Roseburia intestinalis XB6B4 CBL12733.1 D4KZE3  
 TH63_14920   Rufibacter sp. DG31D AKQ46624.1    
 DC20_05270   Rufibacter tibetensis strain 1351 ALI98494.1    
 A4V00_06820   Ruminiclostridium sp. KB18 ANU53764.1    
 Rumal_1055   Ruminococcus albus 7 = DSM 20455 ADU21581.1 E0L9A8  
 Rumal_1567   Ruminococcus albus 7 = DSM 20455 ADU22068.1 E0L9E5  
 RUM_10930   Ruminococcus champanellensis 18P13 = JCM 17042 CBL17246.1 D4LCA1  
 Runsl_4212   Runella slithyformis DSM 19594 AEI50556.1    
 Sde_1593 (Agl27A)   Saccharophagus degradans 2-40 ABD80855.1 Q21KC4  
 α-galactosidase (MelA;AgaB2;SACE_3139) 3.2.1.22 Saccharopolyspora erythraea NRRL 2338 AAC99325.1
CAM02417.1
Q9Z4N5  
 SACE_7065   Saccharopolyspora erythraea NRRL 2338 CAM06226.1 A4FQA1  
 Sked_02790   Sanguibacter keddieii DSM 10542 ACZ20248.1 D1BJJ2  
 NIES4073_07040 (AgaA)   Scytonema sp. NIES-4073 BAZ19831.1    
 Srot_2765   Segniliparus rotundus DSM 44985 ADG99197.1 D6ZD10  
 SAMEA4384070_04176 (AgaA)   Serratia ficaria NCTC12148 SNW05075.1    
 SA2016_1227   Sinomonas atrocyanea KCTC 3377 AMM31909.1    
 Solca_0509   Solitalea canadensis DSM 3403 AFD05641.1    
 Solca_1514   Solitalea canadensis DSM 3403 AFD06589.1    
 Solca_2503   Solitalea canadensis DSM 3403 AFD07538.1    
 SOCE26_058160   Sorangium cellulosum So ce26 AUX44352.1    
 CA265_04030   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS38891.1    
 BV902_06600   Sphingobacterium sp. B29 APU99637.1    
 dextranase (Dex1)   Sphingobacterium sp. V-54 BAE92747.1 Q1XGE4  
 SJA_C2-02330 (GalA)   Sphingobium japonicum UT26S UT26S (= NBRC 101211) BAI98596.1 D4Z7X7  
 BSY17_1069   Sphingobium sp. RAC03 AOF95996.1    
 BSY17_3561   Sphingobium sp. RAC03 AOF94897.1    
 TZ53_09690   Sphingobium sp. YBL2 AJR23954.1    
 YGS_C2P0907   Sphingobium sp. YG1 BBD02893.1    
 YGS_C2P1185   Sphingobium sp. YG1 BBD03171.1    
 YGS_C1P1482   Sphingobium sp. YG1 BBD00227.1    
 A6768_12780   Sphingobium yanoikuyae S72 ATI80778.1    
 A6768_14170   Sphingobium yanoikuyae S72 ATI81009.1    
 BV87_20105   Sphingobium yanoikuyae SHJ ATP20458.1    
 TS85_13070   Sphingomonas hengshuiensis WHSC-8 AJP72510.1    
 AWL63_00260   Sphingomonas panacis DCY99 AOH82646.1    
 AWL63_05190   Sphingomonas panacis DCY99 AOH83452.1    
 AWL63_16455   Sphingomonas panacis DCY99 AOH85298.1    
 NX02_07590   Sphingomonas sanxanigenens DSM 19645 = NX02 AHE53243.1    
 NX02_16900   Sphingomonas sanxanigenens DSM 19645 = NX02 AHE55058.1    
 CVN68_05985   Sphingomonas sp. Cra20 ATY34451.1    
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