Glycoside Hydrolase Family 27

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1384); Uniprot accession (327); PDB accession (46); 3D entries (13); cryst (0)
All (1128) Archaea (1) Bacteria (797) Eukaryota (329) unclassified (1) Structure (13) Characterized (66)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Acid_1472   Candidatus Solibacter usitatus Ellin6076 ABJ82464.1 Q028T8  
 Acid_1588   Candidatus Solibacter usitatus Ellin6076 ABJ82579.1 Q028H3  
 Acid_2820   Candidatus Solibacter usitatus Ellin6076 ABJ83806.1 Q023N4  
 CGC52_01050 (fragment)   Capnocytophaga sp. H2931 ATA74150.1    
 CGC49_01070 (fragment)   Capnocytophaga sp. H4358 ATA72030.1    
 Caci_2554   Catenulispora acidiphila DSM 44928 ACU71472.1 C7PXL9  
 Caci_4439   Catenulispora acidiphila DSM 44928 ACU73303.1 C7PW55  
 Caci_4641   Catenulispora acidiphila DSM 44928 ACU73502.1 C7PY42  
 Caci_4912   Catenulispora acidiphila DSM 44928 ACU73772.1 C7Q336  
 Caci_6873   Catenulispora acidiphila DSM 44928 ACU75712.1 C7Q3E7  
 Caci_7918   Catenulispora acidiphila DSM 44928 ACU76741.1 C7QFG4  
 Caci_4880   Catenulispora acidiphila DSM 44928 ACU73740.1 C7Q1L1  
 Caci_5007   Catenulispora acidiphila DSM 44928 ACU73867.1 C7Q3D1  
 Caci_6252   Catenulispora acidiphila DSM 44928 ACU75106.1 C7QK32  
 Caci_6874   Catenulispora acidiphila DSM 44928 ACU75713.1 C7Q3E8  
 Caci_6974   Catenulispora acidiphila DSM 44928 ACU75804.1 C7Q3N9  
 Caci_7223   Catenulispora acidiphila DSM 44928 ACU76052.1 C7Q739  
 Cseg_1839   Caulobacter segnis ATCC 21756 ADG10312.1 D5VJA3  
 Cseg_2011   Caulobacter segnis ATCC 21756 ADG10480.1 D5VGN7  
 Caul_0313   Caulobacter sp. K31 ABZ69450.1 B0T4F0  
 Caul_2129   Caulobacter sp. K31 ABZ71257.1 B0T7R9  
 Caul_2412   Caulobacter sp. K31 ABZ71539.1 B0SVS1  
 Celf_0438   Cellulomonas fimi ATCC 484 AEE44581.1    
 Celf_3623   Cellulomonas fimi ATCC 484 AEE47731.1    
 Cfla_0456   Cellulomonas flavigena DSM 20109 ADG73371.1 D5UHU7  
 Cfla_2742   Cellulomonas flavigena DSM 20109 ADG75628.1 D5UJJ0  
 Celgi_2554   Cellulomonas gilvus ATCC 13127 AEI13053.1    
 CBP52_12330   Cellulomonas sp. PSBB021 ASR55751.1    
 A5M85_12410   Cellulophaga lytica DAU203 APU11057.1    
 CJA_0246 (Aga27A)   Cellvibrio japonicus Ueda107 ACE85287.1 B3PGJ1  
 α-galactosidase 27A (Aga27A) 3.2.1.22 Cellvibrio mixtus ATCC 12120 AAS19696.1 Q6QT41  
 CBR65_18810   Cellvibrio sp. PSBB006 ARU29319.1    
 CBR65_15165   Cellvibrio sp. PSBB006 ARU28677.1    
 B0D95_16685   Cellvibrio sp. PSBB023 AQT61564.1    
 β-L-arabinopyranosidase (CpArap27;Cpin_5740) 3.2.1.88 Chitinophaga pinensis DSM 2588 ACU63161.1 C7PCU7  
 Cabther_B0051   Chloracidobacterium thermophilum B AEP13059.1    
 CCALI_01466   Chthonomonas calidirosea T49 CCW35282.1    
 CCALI_01571   Chthonomonas calidirosea T49 CCW35387.1    
 AES38_01010   Clavibacter michiganensis subsp. capsici PF008 ALD14007.1    
 α-galactosidase (Ccel_1237) (Gal27A) 3.2.1.22 [Clostridium] cellulolyticum H10 ACL75593.1
ABG76969.1
B8I0L8  
 Ccel_1597 (P50)   [Clostridium] cellulolyticum H10 ACL75949.1 B8I2F6  
 Clocel_3640   Clostridium cellulovorans 743B ADL53311.1 D9SWM9  
 A7L45_08695   Clostridium estertheticum subsp. estertheticum DSM 8809 APC40140.1    
 α-galactosidase (AgaA) (Aga27A) 3.2.1.22 Clostridium josui FERM P-9684 BAB83765.1 Q8VV86  
 Cspa_c41060   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF57859.1    
 CLSAP_38570 (AgaA)   Clostridium saccharoperbutylacetonicum N1-504 AQR96533.1    
 Clo1100_0192   Clostridium sp. BNL1100 AEY64483.1    
 Clo1100_0917   Clostridium sp. BNL1100 AEY65174.1    
 Clo1100_1931   Clostridium sp. BNL1100 AEY66126.1    
 CSTERLE_08105   [Clostridium] stercorarium subsp. leptospartum DSM 9219 ANX01536.1    
 Cst_c16870   [Clostridium] stercorarium subsp. stercorarium DSM 8532 AGI39682.1
AGC68671.1
   
 CSTERTH_08205   [Clostridium] stercorarium subsp. thermolacticum DSM 2910 ANW99008.1    
 CPter291_4451   Collimonas pratensis Ter291 AMP16677.1    
 CPter91_4517   Collimonas pratensis Ter91 AMP06824.1    
 A9D14_04555   Croceicoccus marinus E4A9 ARU15583.1    
 A9D14_16550   Croceicoccus marinus E4A9 ARU17926.1    
 B7495_01920   Cryobacterium sp. LW097 ASD23813.1    
 Deipe_0778   Deinococcus peraridilitoris DSM 19664 AFZ66354.1    
 AAM4_2286   Desulfitobacterium hafniense CED92118.1    
 FH5T_07615   Draconibacterium orientale FH5 AHW59502.1    
 HY57_08620   Dyella japonica A8 AIF47330.1    
 HY57_08625   Dyella japonica A8 AIF47331.1    
 CH75_13760   Dyella jiangningensis SBZ 3-12 AHX14143.1    
 ATSB10_27610   Dyella thiooxydans ATSB10 AND70215.1    
 BBD28_01340   Elizabethkingia anophelis 0422 AQW89382.1    
 BBD31_13750   Elizabethkingia anophelis 3375 AQW98889.1    
 EAAG1_018450   Elizabethkingia anophelis Ag1 ATC41746.1    
 CMV40_18450   Elizabethkingia anophelis AR4-6 ATC49099.1    
 CMV41_18450   Elizabethkingia anophelis AR6-8 ATC45423.1    
 A2T72_02125   Elizabethkingia anophelis CSID_3000521207 AMX53154.1    
 A2T74_02125   Elizabethkingia anophelis CSID_3015183678 AMR40231.1    
 A2T59_02125   Elizabethkingia anophelis CSID_3015183681 AMX56620.1    
 A4C56_02125   Elizabethkingia anophelis CSID_3015183684 AMX46864.1    
 AYC66_10900   Elizabethkingia anophelis E6809 AQX51156.1    
 AYC67_10575   Elizabethkingia anophelis F3543 AQX90912.1    
 A6J37_09115   Elizabethkingia anophelis FDAARGOS_198 ASV78763.1    
 M876_05325   Elizabethkingia anophelis FMS-007 AKH93987.1    
 BD94_1396   Elizabethkingia anophelis NUHP1 AIL45171.1    
 BAZ09_018235   Elizabethkingia anophelis R26 ATC38067.1    
 BBD32_14675   Elizabethkingia endophytica F3201 AQX02611.1    
 BBD30_18570   Elizabethkingia endophytica JM-87 AQW96031.1    
 AYC65_10295   Elizabethkingia genomosp. 3 str. G0146 AQX85376.1    
 BBD34_16330   Elizabethkingia genomosp. 4 str. G4123 AQX10100.1    
 BBD33_14140   Elizabethkingia meningoseptica G4076 AQX06326.1    
 BBD35_16390   Elizabethkingia meningoseptica G4120 AQX14345.1    
 B5G46_14135   Elizabethkingia meningoseptica KC1913 AQX49125.1    
 VO54_01136 (AgaA)   Elizabethkingia miricola BM10 AJW62618.1    
 Emtol_3305   Emticicia oligotrophica DSM 17448 AFK04434.1    
 Emtol_3307   Emticicia oligotrophica DSM 17448 AFK04436.1    
 ECBG_01578   Enterococcus casseliflavus EC20 EEV39309.1    
 AL523_07400   Enterococcus gallinarum FDAARGOS_163 AMG49608.1    
 CO692_10270   Enterococcus gallinarum FDAARGOS_375 ATF72455.1    
 EUS_25330   [Eubacterium] siraeum 70/3 CBK97479.1 D4JWL0  
 ES1_05550   [Eubacterium] siraeum V10Sc8a CBL33680.1 D4MIU7  
 FAES_4801   Fibrella aestuarina BUZ 2 CCH02800.1    
 Fisuc_1773 / FSU_2272   Fibrobacter succinogenes subsp. succinogenes S85 ACX75366.1
ADL25866.1
C9RS30  
 FLA_2823   Filimonas lacunae NBRC 104114 BAV06803.1    
 FLA_5529   Filimonas lacunae NBRC 104114 BAV09480.1    
 FLA_6374   Filimonas lacunae NBRC 104114 BAV10312.1    
 OP10G_1040   Fimbriimonas ginsengisoli Gsoil 348 AIE84408.1    
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