Glycoside Hydrolase Family 27

Activities in Familyα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88); galactan:galactan galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1516); Uniprot accession (327); PDB accession (47); 3D entries (14); cryst (0)
All (1258) Archaea (1) Bacteria (911) Eukaryota (344) Viruses (1) unclassified (1) Structure (14) Characterized (69)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ACP_0049   Acidobacterium capsulatum ATCC 51196 ACO33663.1 C1F805  
 ACP_1583   Acidobacterium capsulatum ATCC 51196 ACO34414.1 C1F6S5  
 AHOG_18410 (AgaA)   Actinoalloteichus hoggarensis DSM 45943 ASO21307.1    
 TL08_17380   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS64276.1    
 UA74_20630   Actinoalloteichus sp. ADI127-7 APU16151.1    
 UA75_21125   Actinoalloteichus sp. GBA129-24 APU22214.1    
 BK816_00760 (fragment)   Actinomyces sp. VUL4_3 AOZ72006.1    
 SAMN04489716_4358   Actinoplanes derwentensis DSM 43941 SDT53490.1    
 AFR_29165   Actinoplanes friuliensis DSM 7358 AGZ44094.1    
 AFR_17105   Actinoplanes friuliensis DSM 7358 AGZ41699.1    
 AMIS_28310   Actinoplanes missouriensis 431 BAL88051.1    
 AMIS_29720   Actinoplanes missouriensis 431 BAL88192.1    
 AMIS_27960   Actinoplanes missouriensis 431 BAL88016.1    
 K924_0031   Actinoplanes sp. N902-109 AGL12187.1
AGL16461.1
   
 L083_2615   Actinoplanes sp. N902-109 AGL16125.1    
 L083_3265   Actinoplanes sp. N902-109 AGL16775.1    
 ACWT_2537   Actinoplanes sp. SE50 ATO81952.1    
 ACWT_5905   Actinoplanes sp. SE50 ATO85320.1    
 ACPL_3009   Actinoplanes sp. SE50/110 AEV83904.1
SLL99360.1
   
 ACPL_6037   Actinoplanes sp. SE50/110 AEV86924.1
SLM02731.1
   
 SAMN04489717_0504   Actinopolymorpha singaporensis DSM 22024 SDR77448.1    
 CDG81_12870   Actinopolyspora erythraea YIM 90600 ASU79030.1    
 Amir_1044   Actinosynnema mirum DSM 43827 ACU35000.1 C6WNT1  
 Amir_1665   Actinosynnema mirum DSM 43827 ACU35614.1 C6WBP6  
 Amir_3106   Actinosynnema mirum DSM 43827 ACU37020.1 C6W7Z9  
 Amir_3796   Actinosynnema mirum DSM 43827 ACU37676.1 C6WD57  
 CNX65_08320   Actinosynnema pretiosum X47 ATE53294.1    
 CNX65_05250   Actinosynnema pretiosum X47 ATE52763.1    
 CNX65_18980   Actinosynnema pretiosum X47 ATE55111.1    
 CNX65_15740   Actinosynnema pretiosum X47 ATE54564.1    
 ADH66_02145   Acutalibacter muris KB18 ASB39562.1    
 ATC03_03505   Agromyces aureus AR33 ANJ25942.1    
 PYTT_2502   Akkermansia glycaniphila SEI00660.1    
 Amuc_1187   Akkermansia muciniphila ATCC BAA-835 ACD05012.1 B2URC7  
 A4V05_01595   Akkermansia muciniphila YL44 ANU60237.1
ANU60237.2
ASB35881.1
   
 SAMN04489726_7426   Allokutzneria albata DSM 44149 SDN61428.1    
 A6F68_00806 (Agaa_1)   Altererythrobacter dongtanensis KCTC 22672 ANY19332.1    
 A6F68_00827 (Agaa_2)   Altererythrobacter dongtanensis KCTC 22672 ANY19353.1    
 AXY_13780   Amphibacillus xylanus NBRC 15112 BAM47510.1    
 AXY_21480   Amphibacillus xylanus NBRC 15112 BAM48280.1    
 AJAP_23110   Amycolatopsis japonica MG417-CF17 AIG77475.1    
 AJAP_05700   Amycolatopsis japonica MG417-CF17 AIG74059.1    
 SAMN04489733_2610   Amycolatopsis keratiniphila FH 1893 SDU27354.1    
 B737_3367 (GalA)   Amycolatopsis mediterranei RB AGT84031.1    
 B737_6702 (GalA)   Amycolatopsis mediterranei RB AGT87365.1    
 B737_7275 (GalA)   Amycolatopsis mediterranei RB AGT87936.1    
 B737_0852 (GalA)   Amycolatopsis mediterranei RB AGT81516.1    
 B737_3604 (GalA)   Amycolatopsis mediterranei RB AGT84268.1    
 B737_7707 (GalA)   Amycolatopsis mediterranei RB AGT88368.1    
 B737_1734 (GalA)   Amycolatopsis mediterranei RB AGT82398.1    
 B737_1908 (GalA)   Amycolatopsis mediterranei RB AGT82572.1    
 B737_8854 (GalA) (fragment)   Amycolatopsis mediterranei RB AGT89514.1    
 B737_8855 (fragment)   Amycolatopsis mediterranei RB AGT89515.1    
 B737_1843 (fragment)   Amycolatopsis mediterranei RB AGT82507.1    
 RAM_17320   Amycolatopsis mediterranei S699 AEK41950.1
AFO76903.1
   
 RAM_37970   Amycolatopsis mediterranei S699 AEK46061.1
AFO80808.1
   
 RAM_09755   Amycolatopsis mediterranei S699 AEK40441.1
AFO75443.1
   
 RAM_08870   Amycolatopsis mediterranei S699 AEK40264.1
AFO75269.1
   
 RAM_40210   Amycolatopsis mediterranei S699 AEK46509.1
AFO81240.1
   
 RAM_34915   Amycolatopsis mediterranei S699 AEK45456.1
AFO80237.1
   
 RAM_18540   Amycolatopsis mediterranei S699 AEK42194.1
AFO77140.1
   
 RAM_46110 (fragment)   Amycolatopsis mediterranei S699 AEK47687.1
AFO82385.1
   
 RAM_09420 (fragment)   Amycolatopsis mediterranei S699 AEK40374.1
AFO75378.1
   
 RAM_46115 (fragment)   Amycolatopsis mediterranei S699 AEK47688.1
AFO82386.1
   
 AMES_0851 (GalA)   Amycolatopsis mediterranei S699 AFO74387.1
AEK39363.1
   
 AMED_0853 (GalA)   Amycolatopsis mediterranei U32 ADJ42673.1 D8I272  
 AMED_1747 (GalA)   Amycolatopsis mediterranei U32 ADJ43558.1 D8HNK7  
 AMED_1923 (GalA)   Amycolatopsis mediterranei U32 ADJ43732.1 D8HQM1  
 AMED_3645 (GalA)   Amycolatopsis mediterranei U32 ADJ45428.1 D8I8U0  
 AMED_6804 (GalA)   Amycolatopsis mediterranei U32 ADJ48528.1 D8I1Z0  
 AMED_7386 (GalA)   Amycolatopsis mediterranei U32 ADJ49100.1 D8I9D3  
 AMED_7823 (GalA)   Amycolatopsis mediterranei U32 ADJ49531.1 D8HQA7  
 AMED_1856 (fragment)   Amycolatopsis mediterranei U32 ADJ43666.1 D8HPN6  
 AMED_3405   Amycolatopsis mediterranei U32 ADJ45191.1 D8I5V2  
 AMED_8989 (fragment)   Amycolatopsis mediterranei U32 ADJ50679.1 D8HKQ2  
 AMED_8990 (fragment)   Amycolatopsis mediterranei U32 ADJ50680.1 D8HKQ3  
 SD37_07195   Amycolatopsis orientalis B-37 ANN15464.1    
 SD37_36940   Amycolatopsis orientalis B-37 ANN20630.1    
 SD37_31500   Amycolatopsis orientalis B-37 ANN19698.1    
 SD37_20615   Amycolatopsis orientalis B-37 ANN17814.1    
 AORI_3230 (GalA)   Amycolatopsis orientalis HCCB10007 AGM05815.1    
 CU254_08365   Amycolatopsis sp. AA4 ATY10474.1    
 CU254_25995   Amycolatopsis sp. AA4 ATY13495.1    
 BKN51_26690   Amycolatopsis sp. BJA-103 AUI61406.1    
 BKN51_08560   Amycolatopsis sp. BJA-103 AUI58265.1    
 Alphα-galactosidase precursor (Var3)   Amycolatopsis sp. DEM30355 AUO14844.1    
 BEQ56_10620 (fragment)   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43887.1    
 A9P82_02800   Arachidicoccus sp. BS20 ANI90574.1    
 A9P82_04630   Arachidicoccus sp. BS20 ANI88636.1    
 AS189_18460 (fragment)   Arthrobacter alpinus ERGS4:06 ALO68114.1    
 isomaltodextranase (ImdA) 3.2.1.94 Arthrobacter dextranolyticus T6 BAD34648.1 Q6BE01  
 isomalto-dextranase (G2d;Imd) 3.2.1.94 Arthrobacter globiformis T6 BAC76886.2
BAA06424.1
Q44052
Q7WSN5
5AWO[A]
5AWP[A]
5AWQ[A]
 MB46_00265   Arthrobacter sp. A3 ALV44177.1    
 Astex_1018   Asticcacaulis excentricus CB 48 ADU12699.1 C5SFM3  
 Astex_2589   Asticcacaulis excentricus CB 48 ADU14234.1 C5SKS3  
 Astex_3319   Asticcacaulis excentricus CB 48 ADU14953.1 C5SLI3  
 Astex_3509   Asticcacaulis excentricus CB 48 ADU15139.1 C5SKZ0  
 SAMN04489747_2047   Auraticoccus monumenti MON 2.2 SDD91531.1    
 AM592_18810   Bacillus gobiensis FJAT-4402 ALC83375.1    
 BH1870   Bacillus halodurans C-125 BAB05589.1
NP_242736.1
Q9KBQ5 3CC1[A,B]
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