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Glycoside Hydrolase Family 27

Known Activitiesα-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); isomalto-dextranase (EC 3.2.1.94); β-L-arabinopyranosidase (EC 3.2.1.88)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; InterPro; PFAM; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (489); Uniprot accession (175); PDB accession (30); 3D entries (10); cryst (1)
Summary
All (329) Archaea (1) Bacteria (137) Eukaryota (190) unclassified (1) Structure (10 - 1 cryst) Characterized (62)
Archaea
Protein NameEC#OrganismGenBankUniprotPDB/3D
 Htur_4675   Haloterrigena turkmenica DSM 5511 ADB63458.1    
Bacteria
Protein NameEC#OrganismGenBankUniprotPDB/3D
 Acid345_3249   Acidobacteria bacterium Ellin345 ABF42250.1 Q1ILK0  
 Acid345_1677   Acidobacteria bacterium Ellin345 ABF40678.1 Q1IR22  
 ACP_0049   Acidobacterium capsulatum ATCC 51196 ACO33663.1    
 ACP_1583   Acidobacterium capsulatum ATCC 51196 ACO34414.1    
 Amir_3106   Actinosynnema mirum DSM 43827 ACU37020.1    
 Amir_3796   Actinosynnema mirum DSM 43827 ACU37676.1    
 Amir_1044   Actinosynnema mirum DSM 43827 ACU35000.1    
 Amir_1665   Actinosynnema mirum DSM 43827 ACU35614.1    
 Amuc_1187   Akkermansia muciniphila ATCC BAA-835 ACD05012.1 B2URC7  
 AMED_1856 (fragment)   Amycolatopsis mediterranei U32 ADJ43666.1    
 AMED_3405   Amycolatopsis mediterranei U32 ADJ45191.1    
 AMED_0853 (GalA)   Amycolatopsis mediterranei U32 ADJ42673.1    
 AMED_6804 (GalA)   Amycolatopsis mediterranei U32 ADJ48528.1    
 AMED_1747 (GalA)   Amycolatopsis mediterranei U32 ADJ43558.1    
 AMED_8989 (fragment)   Amycolatopsis mediterranei U32 ADJ50679.1    
 AMED_8990 (fragment)   Amycolatopsis mediterranei U32 ADJ50680.1    
 AMED_1923 (GalA)   Amycolatopsis mediterranei U32 ADJ43732.1    
 AMED_7386 (GalA)   Amycolatopsis mediterranei U32 ADJ49100.1    
 AMED_7823 (GalA)   Amycolatopsis mediterranei U32 ADJ49531.1    
 AMED_3645 (GalA)   Amycolatopsis mediterranei U32 ADJ45428.1    
 Achl_0056   Arthrobacter chlorophenolicus A6 ACL38059.1 B8H885  
 isomaltodextranase (ImdA) 3.2.1.94 Arthrobacter dextranolyticus T6 BAD34648.1 Q6BE01  
 isomaltodextranase (G2d;Imd) 3.2.1.94 Arthrobacter globiformis T6 BAA06424.1
BAC76886.2		 Q44052
Q7WSN5		 cryst
 BH1870   Bacillus halodurans C-125 BAB05589.1
NP_242736.1		 Q9KBQ5 3CC1[A,B]
 BXY_38430   Bacteriodes xylanisolvens XB1A CBK68793.1    
 BF638R_4272   Bacteroides fragilis 638R CBW24693.1    
 BF638R_0283 (AgL)   Bacteroides fragilis 638R CBW20884.1    
 BF638R_1499   Bacteroides fragilis 638R CBW22036.1    
 BF4189   Bacteroides fragilis NCTC 9343 ATCC 25285 CAH09862.1 Q5L7T7  
 BF0227   Bacteroides fragilis NCTC 9343 ATCC 25285 CAH06003.1 Q5LIM3  
 BF1418   Bacteroides fragilis NCTC 9343 ATCC 25285 CAH07128.1 Q5LFG6  
 BF1485   Bacteroides fragilis YCH46 BAD48236.1    
 BF4391   Bacteroides fragilis YCH46 BAD51129.1    
 BF0271   Bacteroides fragilis YCH46 BAD47020.1    
 BT3592   Bacteroides thetaiotaomicron VPI-5482 AAO78697.1
NP_812503.1		    
 BT3065   Bacteroides thetaiotaomicron VPI-5482 AAO78171.1
NP_811977.1		    
 BT4157   Bacteroides thetaiotaomicron VPI-5482 AAO79262.1
NP_813068.1		    
 BT2662   Bacteroides thetaiotaomicron VPI-5482 AAO77769.1
NP_811575.1		    
 BT0065   Bacteroides thetaiotaomicron VPI-5482 AAO75172.1
NP_808978.1		    
 BVU_0640   Bacteroides vulgatus ATCC 8482 ABR38348.1 A6KY34  
 Bcav_0053   Beutenbergia cavernae DSM 12333 ACQ78319.1    
 BAD_1525   Bifidobacterium adolescentis ATCC 15703 BAF40306.1 A1A3M3  
 BDP_2092 (probable fragment)   Bifidobacterium dentium Bd1 ADB10655.1    
 BLD_1538 (GalA3)   Bifidobacterium longum DJO10A ACD98983.1 B3DPC4  
 BL0177   Bifidobacterium longum NCC2705 AAN24032.1
NP_695396.1		    
 BLJ_1911   Bifidobacterium longum subsp. longum JDM301 ADH01334.1    
 BIP_16080 (fragment)   Bifidobacterium pseudocatenulatum D2CA CBK72759.1    
 Bfae_29570   Brachybacterium faecium DSM 4810 ACU86718.1    
 bglu_2g20960   Burkholderia glumae BGR1 ACR32404.1    
 CIY_22650   Butyrivibrio fibrisolvens 16/4 CBK74937.1    
 bpr_I0090   Butyrivibrio proteoclasticus B316 ADL32841.1    
 bpr_I0205   Butyrivibrio proteoclasticus B316 ADL32954.1    
 Caci_6873   Catenulispora acidiphila DSM 44928 ACU75712.1    
 Caci_7918   Catenulispora acidiphila DSM 44928 ACU76741.1    
 Caci_4880   Catenulispora acidiphila DSM 44928 ACU73740.1    
 Caci_5007   Catenulispora acidiphila DSM 44928 ACU73867.1    
 Caci_2554   Catenulispora acidiphila DSM 44928 ACU71472.1    
 Caci_6252   Catenulispora acidiphila DSM 44928 ACU75106.1    
 Caci_6874   Catenulispora acidiphila DSM 44928 ACU75713.1    
 Caci_6974   Catenulispora acidiphila DSM 44928 ACU75804.1    
 Caci_7223   Catenulispora acidiphila DSM 44928 ACU76052.1    
 Caci_4439   Catenulispora acidiphila DSM 44928 ACU73303.1    
 Caci_4641   Catenulispora acidiphila DSM 44928 ACU73502.1    
 Caci_4912   Catenulispora acidiphila DSM 44928 ACU73772.1    
 Cseg_2011   Caulobacter segnis ATCC 21756 ADG10480.1    
 Cseg_1839   Caulobacter segnis ATCC 21756 ADG10312.1    
 Caul_0313   Caulobacter sp. K31 ABZ69450.1 B0T4F0  
 Caul_2129   Caulobacter sp. K31 ABZ71257.1 B0T7R9  
 Caul_2412   Caulobacter sp. K31 ABZ71539.1 B0SVS1  
 Cfla_0456   Cellulomonas flavigena DSM 20109 ADG73371.1    
 Cfla_2742   Cellulomonas flavigena DSM 20109 ADG75628.1    
 CJA_0246 (Aga27A)   Cellvibrio japonicus Ueda107 ACE85287.1 B3PGJ1  
 α-galactosidase 27A (Aga27A) 3.2.1.22 Cellvibrio mixtus ATCC 12120 AAS19696.1 Q6QT41  
 Cpin_5740   Chitinophaga pinensis DSM 2588 ACU63161.1    
 galactosidase (Ccel_1237) (Gal27A) 3.2.1.22 Clostridium cellulolyticum H10 ATCC 35319 ABG76969.1
ACL75593.1		    
 Ccel_1597 (P50)   Clostridium cellulolyticum H10 ATCC 35319 ACL75949.1    
 Clocel_3640   Clostridium cellulovorans 743B ADL53311.1    
 α-galactosidase (AgaA) (Aga27A) 3.2.1.22 Clostridium josui FERM P-9684 BAB83765.1 Q8VV86  
 EUS_25330   Eubacterium siraeum 70/3 CBK97479.1    
 ES1_05550   Eubacterium siraeum V10Sc8a CBL33680.1    
 Fisuc_1773   Fibrobacter succinogenes subsp. succinogenes S85 ACX75366.1
ADL25866.1		    
 Fjoh_4436   Flavobacterium johnsoniae UW101 ABQ07440.1 A5FBH3  
 Fjoh_4947   Flavobacterium johnsoniae UW101 ABQ07946.1 A5FA25  
 Fjoh_3110   Flavobacterium johnsoniae UW101 ABQ06127.1 A5FFA1  
 FRAAL4014   Frankia alni ACN14a CAJ62656.1 Q0RIL2  
 GYMC61_2733   Geobacillus sp. Y412MC61 ACX79315.1    
 Gbro_3450   Gordonia bronchialis DSM 43247 ACY22644.1    
 Haur_3892   Herpetosiphon aurantiacus ATCC 23779 ABX06526.1 A9AUT8  
 Jden_0514   Jonesia denitrificans DSM 20603 ACV08178.1    
 Krad_3464   Kineococcus radiotolerans SRS30216 ABS04927.1 A6WDN8  
 Micau_3680   Micromonospora aurantiaca ATCC 27029 ADL47206.1    
 MAB_4303   Mycobacterium abscessus CAM64376.1    
 Oter_1363   Opitutus terrae PB90-1 ACB74648.1 B1ZRW9  
 Oter_3220   Opitutus terrae PB90-1 ACB76500.1 B1ZN49  
 Oter_2301   Opitutus terrae PB90-1 ACB75583.1 B1ZQH4  
 Pjdr2_3202   Paenibacillus sp. JDR-2 ACT01843.1    
 Pjdr2_3562   Paenibacillus sp. JDR-2 ACT02195.1    
 Pjdr2_4104   Paenibacillus sp. JDR-2 ACT02733.1    
 Pjdr2_4264   Paenibacillus sp. JDR-2 ACT02888.1    
 Phep_0715   Pedobacter heparinus DSM 2366 ACU02937.1    
 Phep_1839   Pedobacter heparinus DSM 2366 ACU04047.1    
 Phep_2885   Pedobacter heparinus DSM 2366 ACU05083.1    
 Phep_2887   Pedobacter heparinus DSM 2366 ACU05085.1    
 PGN_2032   Porphyromonas gingivalis ATCC 33277 BAG34550.1 B2RMF5  
 PG0085   Porphyromonas gingivalis W83 AAQ65333.1
NP_904434.1		    
 HMPREF0659_A6322   Prevotella melaninogenica ATCC 25845 ADK96067.1    
 PRU_2377   Prevotella ruminicola 23 ADE82935.1    
 Rmar_2597   Rhodothermus marinus DSM 4252 ACY49470.1    
 ROI_10050   Roseburia intestinalis M50/1 CBL08208.1    
 RO1_22250   Roseburia intestinalis XB6B4 CBL12733.1    
 RUM_10930   Ruminococcus sp. 18P13 CBL17246.1    
 Sde_1593 (Agl27A)   Saccharophagus degradans 2-40 ABD80855.1 Q21KC4  
 SACE_7065   Saccharopolyspora erythraea NRRL 2338 CAM06226.1 A4FQA1  
 α-galactosidase (MelA;AgaB2;SACE_3139) 3.2.1.22 Saccharopolyspora erythraea NRRL 2338 AAC99325.1
CAM02417.1		 Q9Z4N5  
 Sked_02790   Sanguibacter keddieii DSM 10542 ACZ20248.1    
 Srot_2765   Segniliparus rotundus DSM 44985 ADG99197.1    
 Acid_0705   Solibacter usitatus Ellin6076 ABJ81706.1 Q02B60  
 Acid_1472   Solibacter usitatus Ellin6076 ABJ82464.1 Q028T8  
 Acid_1588   Solibacter usitatus Ellin6076 ABJ82579.1 Q028H3  
 Acid_2820   Solibacter usitatus Ellin6076 ABJ83806.1 Q023N4  
 dextranase (Dex1)   Sphingobacterium sp. V-54 BAE92747.1 Q1XGE4  
 SJA_C2-02330 (GalA)   Sphingobium japonicum UT26S UT26S (= NBRC 101211) BAI98596.1    
 SAV628 (AgaA1)   Streptomyces avermitilis MA-4680 BAC68338.1
NP_821803.1		    
 SAV1475 (AgaB2)   Streptomyces avermitilis MA-4680 BAC69185.1
NP_822650.1		    
 SAV1077   Streptomyces avermitilis MA-4680 BAC68787.1
NP_822252.1		    
 β-L-arabinopyranosidase (AgaA2;SaArap27A;SAV_2186) (Arap27A) 3.2.1.88 Streptomyces avermitilis MA-4680 BAC69897.1
NP_823362.1		   3A21[A,B]
3A22[A,B]
3A23[A,B]
 SBI_09936   Streptomyces bingchenggensis BCW-1 ADI13054.1    
 SBI_02019   Streptomyces bingchenggensis BCW-1 ADI05140.1    
 SBI_02098   Streptomyces bingchenggensis BCW-1 ADI05219.1    
 SBI_02205   Streptomyces bingchenggensis BCW-1 ADI05326.1    
 SBI_01330   Streptomyces bingchenggensis BCW-1 ADI04451.1    
 SCO0284 or SCF85.12   Streptomyces coelicolor A3(2) CAB54169.1
NP_624613.1		 Q9S2C9  
 α-galactosidase I (α-GalI) (peptide fragment) 3.2.1.22 Streptomyces griseoloalbus      
 SCAB_3891   Streptomyces scabiei 87.22 CBG67596.1    
 SCAB_44311   Streptomyces scabiei 87.22 CBG71494.1    
 TERTU_4091   Teredinibacter turnerae T7901 ACR13989.1    
 XALc_1947   Xanthomonas albilineans GPE PC73 CBA16433.1    
Eukaryota
Protein NameEC#OrganismGenBankUniprotPDB/3D
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Acremonium sp. No.413 BAB08149.1 Q9HFB1  
 ORF (fragment)   Aegilops speltoides ACJ06603.1 B6VCK0  
 galactan:galactan galactosyltransferase 1 (GGT-1) 2.4.1.- Ajuga reptans AAR02007.1 Q6TW99  
 α-N-acetylgalactosaminidase (NagAB)   Anoplopoma fimbria ACQ58057.1    
 At3g26380   Arabidopsis thaliana BAB02198.1
NP_189269.1
NP_189269.2		 Q9LIN8  
 At3g56310   Arabidopsis thaliana AAL67017.1
AAM45068.1
CAB87430.1
NP_191190.2		 Q8VXZ7
Q9LYL2		  
 At5g08380   Arabidopsis thaliana AAM13199.1
AAP37856.1
CAC08338.1
NP_196455.1		 Q8RWB9
Q9FT97		  
 At5g08370   Arabidopsis thaliana AAL90902.1
AAM62753.1
AAN18186.1
ABI00031.1
BAH19885.1
CAC08337.1
NP_568193.1		 Q8RX86
Q9FT98		  
 α-galactosidase A (AglA;AFUA_5G13830;Afu5g13830)   Aspergillus fumigatus Af293 EAL91233.1    
 AFUA_6G02560 (Afu6g02560)   Aspergillus fumigatus Af293 EAL85784.1    
 α-galactosidase B (AglB) 3.2.1.22 Aspergillus fumigatus IMI 385708 ACO72591.1    
 α-galactosidase (AN7152.2) 3.2.1.22 Aspergillus nidulans FGSC A4 ABF50881.1
EAA61404.1		    
 AN7624.2   Aspergillus nidulans FGSC A4 ABF50888.1
EAA61810.1		    
 AN0022.2 (fragment)   Aspergillus nidulans FGSC A4 EAA65341.1    
 α-galactosidase B (AglB) 3.2.1.22 Aspergillus niger CBS 120.49 / N400 CAB46229.1 Q9Y865  
 An11g06330   Aspergillus niger CBS 513.88 CAK96935.1 A2QWT3  
 An14g01800   Aspergillus niger CBS 513.88 CAK46492.1 A2R2S6  
 α-N-acetylgalactosaminidase / α-galactosidase (AglA;An06g00170) 3.2.1.22
3.2.1.49		 Aspergillus niger CBS 513.88 CAK44933.1 A2QL72  
 α-galactosidase II (AglB;An02g11150) (Gal27B) 3.2.1.22 Aspergillus niger CBS 513.88 CAK44445.1 A2QEJ9  
 An01g01320   Aspergillus niger CBS 513.88 CAK43504.1 A2Q7N1  
 α-galactosidase A (Ag1A;AglA) 3.2.1.22 Aspergillus niger N402 AAE69559.1
CAA44950.1		 P28351.1  
 AO090003001305   Aspergillus oryzae RIB40 BAE58368.1    
 AO090023000151   Aspergillus oryzae RIB40 BAE58728.1    
 AO090005000217   Aspergillus oryzae RIB40 BAE55309.1    
 α-galactosidase A (Gla) (fragment)   Ateles belzebuth chamek AAD16964.1 O97898  
 α-N-acetylgalactosaminidase   Bombyx mori ABD36218.1 Q2F5Z9  
 α-N-acetylgalactosaminidase (MGC140188;NagA)   Bos taurus AAI14814.1
AAX46465.1		 Q58DH9  
 R07B7.11   Caenorhabditis elegans Bristol N2 CAB00120.1
NP_506031.1		 Q21801  
 α-galactosidase (Pag2)   Carica papaya AAP04002.1 Q84QC9  
 α-galactosidase (fragment)   Cerastium arcticum ABN13605.1 A3EYF9  
 ORF   Chorthippus parallelus CAX20733.1    
 α-galactosidase 3.2.1.22 Coffea arabica AAA33022.1
AAQ77888.1		 Q42656  
 α-galactosidase (Gal1) 3.2.1.22 Coffea arabica CATURRA ROJO T2308 CAI47559.1 Q5DUH8  
 α-galactosidase (Gal1) 3.2.1.22 Coffea canephora 97 CAI47560.1 Q5DUH7  
 acid α-galactosidase 2 3.2.1.22 Cucumis sativus ABC88435.1 Q2HYY3  
 acid α-galactosidase 1   Cucumis sativus ABC55266.1 Q2MK92  
 Sequence 175 from patent US 7071380 (fragment)   Cucurbita ABH99998.1    
 α-galactosidase 3.2.1.22 Cyamopsis tetragonoloba AAA72859.1
AAE69558.1
CAA32772.1		 P14749.1  
 Unknown (protein for MGC:101584) (probable fragment)   Danio rerio AAH83209.1
AAI64755.1		 Q5XJT6  
 Unknown (protein for MGC:123333) (fragment)   Danio rerio AAI08079.1 Q32PK7  
 Zgc:123333 protein   Danio rerio AAI39644.1 A4QP41  
 α-galactosidase (DEHA0F28490g) 3.2.1.22 Debaryomyces hansenii CBS767 CAG89932.1    
 CG7997   Drosophila melanogaster AAF58008.2
AAL39572.1
AAM68519.1
NP_611119.1
NP_725571.1		 Q7K127
Q9V7N9		  
 CG5731   Drosophila melanogaster AAF52871.2
AAM29494.1
NP_609354.1		 Q8MYY3
Q9VL27		  
 α-galactosidase / β-L-arabinopyranosidase (FoAp2) 3.2.1.22
3.2.1.88		 Fusarium oxysporum 12S BAH10648.1 B7XH21  
 α-galactosidase / β-L-arabinopyranosidase (FoAp1) 3.2.1.22
3.2.1.88		 Fusarium oxysporum 12S BAH10649.1 B7XH22  
 α-N-acetylgalactosaminidase 3.2.1.49 Gallus gallus AAA16614.1
AAE69554.1		 Q90744 1KTB[A]
1KTC[A]
 α-galactosidase (fragment) 3.2.1.22 Ganoderma lucidum      
 unknown   Glycine max ACU23118.1    
 α-galactosidase 3.2.1.22 Glycine max AAA73963.1
AAR65332.1
ACU23822.1		 Q39811  
 unknown (fragment)   Glycine max ACU20569.1    
 unknown (fragment)   Glycine max ACU20662.1    
 α-galactosidase (Gla) 3.2.1.22 Helianthus annuus BAC66445.1 Q84VQ7  
 ORF (fragment)   Heterocapsa triquetra AAW79376.1 Q5ENL7  
 α-galactosidase A (Gla;α-GAL) 3.2.1.22 Homo sapiens AAA51676.1
AAA52514.1
AAA52559.1
AAB64203.1
AAE66433.1
AAE69556.1
AAH02689.1
AAN92813.1
AAP35510.1
AAQ31818.1
AAQ68716.1
AAQ81221.1
AAY03282.1
AAY71885.1
AAY71886.1
AAY71887.1
AAY71888.1
AAY71889.1
AAY71890.1
AAY71891.1
AAY71892.1
AAY71893.1
AAY71894.1
AAY72531.1
AAY72532.1
AAY72533.1
AAY72534.1
AAY72535.1
AAY72536.1
AAY72537.1
AAY72538.1
AAY72539.1
AAY72540.1
ABE23230.1
ABL16360.1
ABL21591.1
ACH14962.1
ACH14962.1
ACK10792.1
BAA34059.1
BAD96347.1
BAF83784.1
BAG59647.1
CAA29232.1
CAA32617.1
CAB55878.1
CAC09605.1
CAE85447.1
CAV33302.1
NP_000160.1		 P06280.1
Q53Y83		 1R46[A,B]
1R47[A,B]
3GXN[A,B]
3GXP[A,B]
3GXT[A,B]
3HG2[A,B]
3HG3[A,B]
3HG4[A,B]
3HG5[A,B]
3LX9[A,B]
3LXA[A,B]
3LXB[A,B]
3LXC[A,B]
 α-N-acetylgalactosaminidase / α-galactosidase B (bK250D10.5;NagA;α-NAGAL) 3.2.1.22
3.2.1.49		 Homo sapiens AAA36351.1
AAA51677.1
AAA59902.1
AAB06718.1
AAE69555.1
AAH00095.1
ACM80412.1
ACM85401.1
ACM85401.1
CAB41237.1
CAG30413.1
CAX14869.1
CAX14870.1
NP_000253.1		 P17050.2 3H53[A,B]
3H54[A,B]
3H55[A,B]
3IGU[A,B]
 α-galactosidase (fragment)   Hordeum vulgare CAA74161.1 O04943  
 α-galactosidase (fragment)   Hordeum vulgare CAA74160.1 O04944  
 α-galactosidase (Agl1) 3.2.1.22 Hypocrea jecorina   Q92456 1SZN[A]
1T0O[A]
 α-galactosidase 1 (Agl1) 3.2.1.22 Hypocrea jecorina RUTC-30 CAA93244.1 Q92456  
 α-galactosidase 3 (Agl3) 3.2.1.22 Hypocrea jecorina RUTC-30 CAA93246.1 Q92451  
 α-galactosidase   Lachancea cidri AAA35280.1 Q99172  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 2861 BAD26713.1 Q6F3P6  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 4104 BAD26714.1 Q6F3P8  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 4566 BAD26715.1 Q6F3P5  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 4568 BAD26716.1 Q6F3P6  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 4569 BAD26717.1 Q6F3P5  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 4570 BAD26718.1 Q6F3P4  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 4798 BAD26719.1 Q6F3P4  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 4799 BAD26720.1 Q6F3P4  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 4800 BAD26721.1 Q6F3P4  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 4801 BAD26722.1 Q6F3P4  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 5828 BAD26723.1 Q6F3P6  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri CBS 6545 BAD26724.1 Q6F3P5  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 6546 BAD26725.1 Q6F3N7  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 6547 BAD26726.1 Q6F3N5  
 α-galactosidase (MelK) (possible fragment)   Lachancea kluyveri CBS 6548 BAD26727.1 Q6F3N5  
 α-galactosidase (MELk) (fragment)   Lachancea kluyveri CBS 6626 BAD26728.1 Q6F3N5  
 α-galactosidase (MELk4) (fragment)   Lachancea kluyveri IFO 10847 BAB18272.1 Q9HGJ7  
 α-galactosidase (MELk5) (fragment)   Lachancea kluyveri IFO 10848 BAB18273.1 Q9HGJ6  
 α-galactosidase (MELk1) (fragment)   Lachancea kluyveri IFO 1685 BAB16832.1 Q9HGK0  
 α-galactosidase (MELk2) (fragment)   Lachancea kluyveri IFO 1811 BAB16833.1 Q9HGJ9  
 α-galactosidase (MELk3) (fragment)   Lachancea kluyveri IFO 1892 BAB16834.1 Q9HGJ8  
 α-galactosidase (MelK) (fragment)   Lachancea kluyveri NBRC 10955 BAD26712.1 Q6F3P4  
 α-galactosidase (MELth1)   Lachancea thermotolerans NBRC 10066 BAE93465.1 Q1MW33  
 α-galactosidase (MELth2)   Lachancea thermotolerans NBRC 10067 BAE93466.1 Q1MW32  
 α-N-acetylgalactosaminidase (NagAB)   Lepeophtheirus salmonis Pacific form ACO11760.1    
 MG09805.4   Magnaporthe grisea 70-15 EAA53842.1
XP_364960.1		    
 MG09989.4   Magnaporthe grisea 70-15 EAA49825.1
XP_365144.1		    
 MG05620.4   Magnaporthe grisea 70-15 XP_360246.1    
 MG04658.4   Magnaporthe grisea 70-15 EAA50899.1
XP_362213.1		    
 MtrDRAFT_AC149210g12v2   Medicago truncatula ABD32283.2
ABO80215.1		 Q2HU62  
 MTYFL_FM_FN_FO1G-H-16   Medicago truncatula ACJ85800.1 B7FM17  
 MtrDRAFT_AC164249g26v1 or MtrDRAFT_AC153004g1v1   Medicago truncatula ABE26636.1
ABE26636.2
ABE87553.1		    
 MtrDRAFT_AC138580g35v1   Medicago truncatula ABE81161.1
ABE81161.2		    
 α-N-acetylgalactosaminidase (NagA) 3.2.1.49 Mus musculus AAC28851.1
AAH21631.1
AAL87527.1
AAL87528.1
BAC36620.1
BAE21730.1
BAE31642.1
CAA11703.1
NP_032695.2		 Q9QWR8
Q9QWR8.2		  
 α-galactosidase A (Gls;Agl) (lysosomal) 3.2.1.22 Mus musculus AAA74453.1
AAA96749.1
AAB47244.1
AAC52583.1
AAC52584.1
AAH09021.1
BAC30508.1
BAC35819.1
BAE26260.1
BAE37692.1
BAE38627.1
BAE38657.1
CAM19136.1
CAM19137.1
NP_038491.1		 P51569
Q8BGZ6		  
 Os10g0492900   Oryza sativa Japonica Group AAG13536.1
AAP54408.1
BAF26849.1
NP_922121.1		 Q9FWV8  
 α-galactosidase III (Os07g0679300) 3.2.1.22 Oryza sativa Japonica Group BAC79549.1
BAD31216.1
BAF22553.1
BAG94006.1		 Q7XIV4  
 Os01g0518500   Oryza sativa Japonica Group BAB91950.1
BAD73696.1
BAF05117.1
BAG90573.1		 Q5QLK3  
 α-galactosidase II (Os07g0452100) 3.2.1.22 Oryza sativa Japonica Group BAC55816.1
BAC84411.1
BAF21463.1		 Q0D6R0  
 α-galactosidase I (Os10g0493600) 3.2.1.22 Oryza sativa Japonica Group AAM92832.1
AAO85428.1
AAP54412.1
ABB47819.1
BAB12570.1
BAF26853.1
NP_922125.1		 Q9FXT4
Q9FXT4.1		 1UAS[A]
 α-N-acetylgalactosaminidase (NagA)   Ovis aries ACB87536.1 B2LSM7  
 Pc21g14820   Penicillium chrysogenum Wisconsin 54-1255 CAP96379.1 B6HIL7  
 α-galactosidase (aGal) 3.2.1.22 Penicillium purpurogenum 618 BAA22992.1 O13295  
 α-galactosidase I (Agl1;AglI) 3.2.1.22 Penicillium simplicissimum VTT-D-78090 CAA08915.1 O94221  
 α-galactosidase III (AgalIII) (peptide fragment) 3.2.1.22 Penicillium simplicissimum VTT-D-78090      
 α-galactosidase (fragment)   Petunia x hybrida AAQ82455.1 Q6UAY5  
 α-galactosidase (AgalB) 3.2.1.22 Phanerochaete chrysosporium ME446 AAG24511.1 Q9HFZ9  
 α-galactosidase (AgalA) 3.2.1.22 Phanerochaete chrysosporium ME446 AAG24510.1 Q9HG00  
 α-galactosidase 3.2.1.22 Phaseolus vulgaris AAA73964.1
AAR65334.1		 Q41100  
 WS02719_G07 (fragment)   Picea sitchensis ABR16121.1 B8LKE1  
 unknown (WS02810_D08)   Picea sitchensis ABK24468.1 A9NV07  
 unknown (WS02910_M11)   Picea sitchensis ABK24922.1 A9NWB1  
 unknown (WS0294_N01)   Picea sitchensis ABK25009.1
ABR17777.1		 A9NWJ8  
 WS0285_J03   Picea sitchensis ABR17992.1 B8LQR2  
 unknown   Picea sitchensis ADE77708.1    
 α-galactosidase 1 (Gal1) 3.2.1.22 Pisum sativum CAF34023.1 Q5ZP79  
 unnamed protein product   Podospora anserina S mat+ CAP71790.1 B2B3V4  
 unnamed protein product   Podospora anserina S mat+ CAP65080.1 B2AM92  
 Unknown (protein for MGC:95262)   Rattus norvegicus AAH82084.1 Q66H12  
 ORF (fragment)   Rimicaris exoculata ACR78680.1    
 α-galactosidase (Mel) (fragment)   Saccharomyces bayanus CBS 380 AAQ17217.1 Q6WN36  
 galactosidase / melibiase   Saccharomyces carlsbergensis AAA34770.1    
 α-galactosidase (MEL) 3.2.1.22 Saccharomyces carlsbergensis NCYC396 AAA34769.1 Q03647  
 α-galactosidase 1 (Mel1) 3.2.1.22 Saccharomyces cerevisiae AAD41358.1
AAE69557.1
CAA26888.1		 P04824.1 3LRK[A]
3LRL[A]
3LRM[A,B,C,D]
 α-galactosidase 2 (Mel2) 3.2.1.22 Saccharomyces cerevisiae CAA85737.1 P41945  
 α-galactosidase 5 (Mel5) 3.2.1.22 Saccharomyces cerevisiae CAA85740.1 P41946  
 α-galactosidase 6 (Mel6) 3.2.1.22 Saccharomyces cerevisiae CAA85739.1 P41947  
 α-galactosidase (MEL)   Saccharomyces cerevisiae NCYC686 AAL07760.1 Q96UV4  
 α-galactosidase (MELj) 3.2.1.22 Saccharomyces mikatae IFO 1816 CAA64760.1 Q11129  
 α-galactosidase (MELp) 3.2.1.22 Saccharomyces paradoxus 61-248 CAA64759.1 Q09187  
 α-galactosidase (Mel) (fragment)   Saccharomyces pastorianus CBS 1538 AAQ17218.1 Q6WN35  
 BT072612 (fragment)   Salmo salar ACN60308.1    
 α-N-acetylgalactosaminidase (NagaB) (fragment)   Salmo salar ACI33826.1 B5X3E5  
 AgaL   Salmo salar ACN10914.1    
 NagaB   Salmo salar ACN10976.1    
 ORF   Salvia miltiorrhiza AAU86897.1 Q5XTZ3  
 SJCHGC03011 (fragment)   Schistosoma japonicum AAX25683.2 Q5C3U2  
 α-N-acetylgalactosaminidase (NagA)   Schistosoma japonicum AAW26732.1
CAX70041.1
CAX70042.1
CAX70043.1		 Q5DBS4  
 unknown (fragment)   Schistosoma japonicum AAX25755.1
AAX25755.2		 Q5C3M0  
 Smp_170830 (fragment)   Schistosoma mansoni CAY17473.1    
 Smp_089270 (fragment)   Schistosoma mansoni CAY17474.1    
 Smp_170840 (fragment)   Schistosoma mansoni CAY17475.1    
 Smp_179260 (possible fragment)   Schistosoma mansoni CAZ37305.1    
 Smp_179260 (possible fragment)   Schistosoma mansoni CAZ37305.1    
 Smp_089290   Schistosoma mansoni CAY17477.1    
 Smp_179250 (fragment)   Schistosoma mansoni CAZ37304.1    
 Smp_186710 (fragment)   Schistosoma mansoni CAZ38188.1    
 α-galactosidase (Mel1;SPAC869.07c) 3.2.1.22 Schizosaccharomyces pombe 972h- CAB60017.1
NP_595012.1		 Q9URZ0  
 ORF (fragment)   Secale cereale ACJ06604.1 B6VCK1  
 unnamed protein product   Senna occidentalis CAA03733.1    
 α-galactosidase (LeaGal) 3.2.1.22 Solanum lycopersicum AAF04591.1
AAG16693.1		 Q9FUR8
Q9SP05		  
 α-galactosidase A   Sus scrofa ACD67895.1
ACD67896.1		    
 α-N-acetylgalactosaminidase (NagA)   Sus scrofa ACA43013.1 B1PK16  
 Agal   Takifugu rubripes CAC44626.1 Q90WL7  
 α-galactosidase (Gal1)   Talaromyces emersonii ABU94728.1 A7XZT2  
 α-galactosidase (peptide fragments) 3.2.1.22 Thermomyces lanuginosus IMI 158749      
 α-galactosidase (MELt) 3.2.1.22 Torulaspora delbrueckii BAA86883.1 Q9UVD6  
 Sequence 107403 from patent US 7214786   Triticum aestivum ABT19933.1    
 Sequence 105792 from patent US 7214786   Triticum aestivum ABT18322.1    
 ORF (fragment)   Triticum monococcum ACJ06602.1 B6VCJ9  
 ORF (fragment)   Triticum urartu ACJ06601.1 B6VCJ8  
 α-galactosidase I (GalI;UvGalI) 3.2.1.22 Umbelopsis vinacea     3A5V[A]
 α-galactosidase II 3.2.1.22 Umbelopsis vinacea BAA33931.1 O93816  
 α-galactosidase 3.2.1.22 Umbelopsis vinacea AAB35252.2 Q02402  
 α-N-acetylgalactosaminidase I (peptide fragment) 3.2.1.49 uncultured eukaryote (squid)      
 α-N-acetylgalactosaminidase II (peptide fragment) 3.2.1.49 uncultured eukaryote (squid)      
 VITISV_041251   Vitis vinifera CAN81856.1 A5C5Q1  
 VITISV_043596   Vitis vinifera CAN75523.1 A5ACL5  
 VITISV_001661 (fragment)   Vitis vinifera CAN75822.1 A5AM08  
 VITISV_000962   Vitis vinifera CAN66885.1 A5ALZ9  
 Unknown (protein for IMAGE:7874727)   Xenopus (Silurana) tropicalis AAI22060.1
AAI54864.1		 A8WGV2  
 LOC100145767 protein   Xenopus (Silurana) tropicalis AAI61735.1 B1WBF4  
 Unknown (protein for MGC:81044)   Xenopus laevis AAH71089.1 Q6GR44  
 Unknown (protein for MGC:130872)   Xenopus laevis AAI06338.1 Q3KQ87  
 Unknown (protein for IMAGE:5156001)   Xenopus laevis AAH72931.1 Q6GQ17  
 unknown (probable fragment)   Zea mays ACG46467.1    
 unknown   Zea mays ACG27087.1 B6SQF4  
 unknown (fragment)   Zea mays ACG34083.1    
 unknown   Zea mays ACG38718.1 B6TNN5  
 unknown (ZM_BFb0086O11)   Zea mays B73 ACF80887.1 B4FFJ4  
 unknown (ZM_BFc0121L19)   Zea mays B73 ACF88218.1 B4FA27  
 unknown (ZM_BFc0169O05)   Zea mays B73 ACF88364.1 B4G1X1  
 unknown   Zea mays B73 ACN31209.1
ACR34399.1		    
 unknown (ZM_BFb0345J15)   Zea mays B73 ACF83970.1 B4F9X0  
 unknown (ZM_BFc0123C14) (fragment)   Zea mays B73 ACF78685.1 B4F992  
 unknown (ZM_BFc0061B12)   Zea mays B73 ACF78913.1 B4F9X0  
 unknown (ZM_BFc0036L21)   Zea mays B73 ACF78970.1
ACN34719.1		 B4FA27  
 α-galactosidase (MELr) 3.2.1.22 Zygosaccharomyces mrakii IFO 1835 BAA99555.1 Q9P4V4  
unclassified
Protein NameEC#OrganismGenBankUniprotPDB/3D
 MedDCM-OCT-S04-C188-cds6 / ENSANGP00000020847   uncultured organism MedDCM-OCT-S04-C188 ADD95732.1