Glycoside Hydrolase Family 25

Activities in Familylysozyme (EC 3.2.1.17)
Mechanism Retaining (inferred)
3D Structure Status( β / α ) 5 ( β ) 3 TIM-like
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
External resourcesCAZypedia; PROSITE;
Statistics GenBank accession (5628); Uniprot accession (780); PDB accession (21); 3D entries (12); cryst (0)
All (5410) Archaea (3) Bacteria (5162) Eukaryota (35) Viruses (207) unclassified (3) Structure (12) Characterized (31)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 BA_1060   Bacillus anthracis str. A2012 NP_654420.1  
2H87[nd]
 lysozyme (BA3501;BaGH25c) 3.2.1.17 Bacillus anthracis str. Ames AAP27267.1
NP_845781.1
Q81YN8
2WAG[A] 1.40
 BAS0460   Bacillus anthracis str. Sterne AAT52791.1
AJH44297.1
 
3HMC[A] 1.44
 lyzozyme (SleM) 3.2.1.17 Clostridium perfringens S40 BAA20125.1 O06496
5JIP[A,B] 1.80
 autolytic lysozyme (LytC;spr1431) 3.2.1.17 Streptococcus pneumoniae R6 AAL00235.1 Q8DP07
2WW5[A] 1.61
2WWC[A] 1.75
2WWD[A] β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-α-D-GlcpNAc
2.25
 virulence factor (GhiA;GHIP;SpGHIP;SP_0987)   Streptococcus pneumoniae TIGR4 AAK75106.1  
4FF5[A] 1.86
 lysozyme (Cellosyl) 3.2.1.17 Streptomyces coelicolor MULLER    
1JFX[A] 1.65
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 lysozyme (Afgh25;Afu8g06980) (6622)   Aspergillus fumigatus Af293 EDP48644.1  
2X8R[A,B,C,D,E,F] 1.70
Viruses
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 muramidase / endolysin (Psm;CPR_C0050) 3.2.1.17 Clostridium perfringens SM101 ABG87925.1 Q0SPG7
4KRT[A,B] 1.92
4KRU[A] α-D-GlcpNAc
β-D-GlcpNAc
1.37
 endolysin (Ply40;gp26)   Listeria phage P40 ACI00386.1 B6D7J9
4JZ5[A] 1.10
 lysozyme (Cpl1;Cpl-1) 3.2.1.17 Streptococcus phage Cp-1 AAA32204.1
CAA87744.1
NP_044837.1
P15057
1H09[A] 2.1
1OBA[A] 2.45
2IXU[A] β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-α-D-GlcpNAc
2.28
2IXV[A] β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-α-D-GlcpNAc
1.96
2J8F[A] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc-(1-1)-methyl
1.84
2J8G[A] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc-(1-4)-D-1-deoxy-GlcpNAc
1.69
 lysin (PlyB) 3.2.1.17 unidentified phage BcpI    
2NW0[B] 1.60
2NW0[A] 1.60
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