Glycoside Hydrolase Family 25

Activities in Familylysozyme (EC 3.2.1.17)
Mechanism Retaining (inferred)
3D Structure Status( β / α ) 5 ( β ) 3 TIM-like
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
External resourcesCAZypedia; PROSITE;
Statistics GenBank accession (14082); Uniprot accession (92); PDB accession (23); 3D entries (14); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 lysozyme (BA3501;BaGH25c) 3.2.1.17 pubmed
Bacillus anthracis str. Ames AAP27267.1
NP_845781.1
A0A3P1U4Q1
A0A6L7H2K3
Q81YN8
2WAG[A]
 bacteriolytic enzyme (PlyPH;BA2805) 3.2.1.17 pubmed
Bacillus anthracis str. Ames AAP26640.1
NP_845154.1
A0A2P0HFC3
A0A6L8NZR3
Q81PJ7
 
 lysozyme CH/muramidase (CAC0554) 3.2.1.17 pubmed
Clostridium acetobutylicum ATCC 824 AAA23250.1
AAK78533.1
NP_347193.1
P34020  
 lyzozyme (SleM) 3.2.1.17 pubmed
Clostridium perfringens S40 BAA20125.1 O06496 5JIP[A,B]
 lysozyme (CPE1314) 3.2.1.17 pubmed
Clostridium perfringens str. 13 BAB81020.1
NP_562230.1
I1SBA5
O06496
 
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 pubmed
Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
Q833G2  
 N-acetylmuramidase (AtlB;EF0355) 3.2.1.17 pubmed
Enterococcus faecalis V583 AAO80218.1
NP_814147.1
Q838S8  
 lysozyme (LysL) 3.2.1.17 pubmed
Lactococcus lactis subsp. lactis CAA10710.1 Q9ZEK6  
 cell wall lytic enzyme (LysA) 3.2.1.17 pubmed
Limosilactobacillus fermentum BR11 AAS57574.1 Q64J93  
 autolysin (AtlA) 3.2.1.17 pubmed
Streptococcus criceti E49 BAH11115.1 B7X9H1  
 autolysin (AmL) 3.2.1.17 pubmed
Streptococcus mutans C67-1 BAF03559.1 Q0KK88  
 β-1,4-N-acetylmuramidase (LytC) 3.2.1.17 pubmed
Streptococcus pneumoniae M31 CAA08765.1
AAQ38109.1
AAY71755.1
Q9Z4J8  
 autolytic lysozyme (LytC;spr1431) 3.2.1.17 pubmed
Streptococcus pneumoniae R6 AAL00235.1 Q8DP07 2WW5[A]
2WWC[A]
2WWD[A]
 lysozyme (Cellosyl) 3.2.1.17 pubmed
Streptomyces coelicolor MULLER     1JFX[A]
 lysozyme CH / M1 3.2.1.17 doi
Streptomyces globisporus AAA26687.1 P25310  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 GH25 muramidase 3.2.1.17 doi
Arcopilus cupreus QNJ46215.1 A0A7S6K784  
 GH25 muramidase 3.2.1.17 doi
Ascobolus sp. QNJ46252.1 A0A7S6G7K8  
 GH25 muramidase 3.2.1.17 doi
Ascobolus sp. QNJ46241.1 A0A7S6G7X6  
 GH25 muramidase 3.2.1.17 doi
Aspergillus deflectus QNJ46212.1 A0A7S6K3Z8  
 GH25 muramidase 3.2.1.17 doi
Aspergillus inflatus QNJ46248.1 A0A7S6G7I7  
 lysozyme (AN6470.2) 3.2.1.17 pubmed
Aspergillus nidulans FGSC A4 EAA58492.1
ABF50879.1
A0A1U8QG74
C8V058
G5EAV9
Q5AZ10
 
 GH25 muramidase 3.2.1.17 doi
Aspergillus sp. QNJ46219.1 A0A7S6G7I4  
 GH25 muramidase 3.2.1.17 doi
Blackwellomyces cardinalis QNJ46231.1 A0A7S6K8D4  
 lysozyme CH 3.2.1.17 pubmed
Chalara sp.   P00721  
 GH25 muramidase 3.2.1.17 doi
Clonostachys rossmaniae QNJ46247.1 A0A7S6G7X5  
 GH25 muramidase 3.2.1.17 doi
Coniochaeta sp. QNJ46234.1 A0A7S6G7I9  
 GH25 muramidase 3.2.1.17 doi
Coniothyrium sp. QNJ46242.1 A0A7S6K403  
 GH25 muramidase 3.2.1.17 doi
Cordyceps farinosa QNJ46225.1 A0A7S6G7J0  
 GH25 muramidase 3.2.1.17 doi
Curreya sp. QNJ46240.1 A0A7S6G7J7  
 GH25 muramidase 3.2.1.17 doi
Daldinia fissa QNJ46235.1 A0A7S6G7S9  
 GH25 muramidase 3.2.1.17 doi
Deconica coprophila QNJ46222.1 A0A7S6G7J2  
 lysozyme 1 (EHI_199110) 3.2.1.17 pubmed
Entamoeba histolytica HM-1:IMSS EAL47908.1
CAA60916.1
C4LWV6
Q27650
 
 GH25 muramidase 3.2.1.17 doi
Flammulina velutipes KACC42780 QNJ46237.1 A0A7S6G7K2  
 GH25 muramidase 3.2.1.17 doi
Gelasinospora cratophora QNJ46256.1 A0A7S6G7Y0  
 GH25 muramidase 3.2.1.17 doi
Hamigera paravellanea QNJ46238.1 A0A7S6G7I8  
 GH25 muramidase 3.2.1.17 doi
Hypholoma polytrichi QNJ46260.1 A0A7S6K794  
 GH25 muramidase 3.2.1.17 doi
Hypoxylon sp. QNJ46254.1 A0A7S6K8W7  
 GH25 muramidase 3.2.1.17 doi
Hypoxylon sp. QNJ46255.1 A0A7S6G7K5  
 GH25 muramidase 3.2.1.17 doi
Lecanicillium sp. QNJ46224.1 A0A7S6K8V9  
 GH25 muramidase 3.2.1.17 doi
Lecanicillium sp. QNJ46223.1 A0A7S6G7H9  
 GH25 muramidase 3.2.1.17 doi
Lecanicillium sp. QNJ46227.1 A0A7S6K400  
 GH25 muramidase 3.2.1.17 doi
Malbranchea flava QNJ46229.1 A0A7S6G7W8  
 GH25 muramidase 3.2.1.17 doi
Metapochonia bulbillosa QNJ46239.1 A0A7S6K8W3  
 GH25 muramidase 3.2.1.17 doi
Metarhizium sp. QNJ46249.1 A0A7S6G7J9  
 GH25 muramidase 3.2.1.17 doi
Mucoromycotina sp. QNJ46253.1 A0A7S6G7K0  
 GH25 muramidase 3.2.1.17 doi
Onygena equina QNJ46220.1 A0A7S6G7S4  
 GH25 muramidase 3.2.1.17 doi
Paecilomyces sp. (in: Hypocreales) QNJ46217.1 A0A7S6G7W1  
 GH25 muramidase 3.2.1.17 doi
Paecilomyces sp. (in: Hypocreales) QNJ46218.1 A0A7S6G7H1  
 GH25 muramidase 3.2.1.17 doi
Paracremonium inflatum QNJ46245.1 A0A7S6K789  
 GH25 muramidase 3.2.1.17 doi
Parengyodontium album QNJ46230.1 A0A7S6K785  
 GH25 muramidase 3.2.1.17 doi
Penicillium citrinum QNJ46221.1 A0A7S6G7I3  
 GH25 muramidase 3.2.1.17 doi
Penicillium sp. QNJ46228.1 A0A7S6K840  
 GH25 muramidase 3.2.1.17 doi
Podospora bulbillosa QNJ46214.1 A0A7S6G7V7  
 GH25 muramidase 3.2.1.17 doi
Poronia punctata QNJ46210.1 A0A7S6G7I2  
 GH25 muramidase 3.2.1.17 doi
Poronia punctata QNJ46209.1 A0A7S6K8V3  
 GH25 muramidase 3.2.1.17 doi
Purpureocillium lilacinum QNJ46232.1 A0A179GAU8  
 GH25 muramidase 3.2.1.17 doi
Pycnidiophora sp. QNJ46213.1 A0A7S6K835  
 GH25 muramidase 3.2.1.17 doi
Rhizomucor pusillus QNJ46208.1 A0A7S6G7H2  
 GH25 muramidase 3.2.1.17 doi
Rosellinia sp. QNJ46236.1 A0A7S6G7J1  
 GH25 muramidase 3.2.1.17 doi
Simplicillium obclavatum QNJ46250.1 A0A7S6G7T6  
 GH25 muramidase 3.2.1.17 doi
Sodiomyces alcalophilus JCM 7366 QNJ46261.1 A0A7S6K8E4 6ZM8[A]
 GH25 muramidase 3.2.1.17 doi
Sporormia fimetaria QNJ46216.1 A0A7S6K8C8  
 GH25 muramidase 3.2.1.17 doi
Stropharia semiglobata QNJ46257.1 A0A7S6K406  
 GH25 muramidase 3.2.1.17 doi
Stropharia semiglobata QNJ46258.1 A0A7S6K850  
 GH25 muramidase 3.2.1.17 doi
Stropharia semiglobata QNJ46259.1 A0A7S6G7Y2  
 GH25 muramidase 3.2.1.17 doi
Thermoascus aurantiacus QNJ46251.1 A0A7S6G7K1  
 GH25 muramidase 3.2.1.17 doi
Thermomucor indicae-seudaticae QNJ46226.1 A0A7S6G7W7  
 GH25 muramidase 3.2.1.17 doi
Trichobolus zukalii QNJ46207.1 A0A7S6G7I6 6ZMV[A,B]
 GH25 muramidase 3.2.1.17 doi
Umbelopsis westeae QNJ46233.1 A0A7S6G7H8  
 GH25 muramidase 3.2.1.17 doi
Westerdykella sp. QNJ46244.1 A0A7S6G7X7  
 GH25 muramidase 3.2.1.17 doi
Xylariaceae sp. QNJ46246.1 A0A7S6K8D9  
 GH25 muramidase 3.2.1.17 doi
Yunnania penicillata QNJ46243.1 A0A7S6K843  
 GH25 muramidase 3.2.1.17 doi
Zopfiella sp. QNJ46211.1 A0A7S6G7W5  
Viruses
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 lysin (PlyB) 3.2.1.17 pubmed
Bacteriophage sp. BcpI     2NW0[B]
2NW0[A]
 endolysin (CTP1L;phiCTP1_gp29) 3.2.1.17 pubmed
Clostridium phage phiCTP1 ADL40330.1 D9ZNF3 5A6S[A]
 muramidase / endolysin (Psm;CPR_C0050) 3.2.1.17 pubmed
Clostridium perfringens SM101 ABG87925.1 Q0SPG7 4KRT[A,B]
4KRU[A]
 endolysin (Mur-LH) 3.2.1.17 pubmed
Lactobacillus phage f-0303 AAQ06663.1 Q71JA9  
 endolysin (Mur) 3.2.1.17 pubmed
Lactobacillus phage LL-H AAC00557.1 Q38359  
 lysozyme CH 3.2.1.17 pubmed
Lactobacillus phage mv1 AAA32264.1 P33486  
 lysin (Lys) 3.2.1.17 pubmed
Lactobacillus phage phiadh CAB52540.1
NP_050170.1
Q38317  
 endolysin (Lyb5) 3.2.1.17 pubmed
Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 peptidoglycan endolysin 3.2.1.17 pubmed
Streptococcus phage B30 AAN28166.2 Q8HA43  
 lysozyme / endolysin / muramidase (Cpl-7;Cpl7) 3.2.1.17 pubmed
Streptococcus phage CP-7 AAA72844.2
CDS43823.1
A0A068YG91
P19385
 
 lysozyme 3.2.1.17 pubmed
Streptococcus phage CP-9 AAA72845.1 P19386  
 lysozyme (Cpl1;Cpl-1) 3.2.1.17 pubmed
Streptococcus phage Cp1 AAA32204.1
CAA87744.1
NP_044837.1
P15057 1H09[A]
1OBA[A]
2IXU[A]
2IXV[A]
2J8F[A]
2J8G[A]
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