Glycoside Hydrolase Family 25

Known Activitieslysozyme (EC 3.2.1.17)
Mechanism Retaining (inferred)
3D Structure Status( β / α ) 5 ( β ) 3 TIM-like
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
External resourcesCAZypedia; PROSITE;
Statistics GenBank accession (2234); Uniprot accession (779); PDB accession (20); 3D entries (11); cryst (0)
All (2038) Archaea (2) Bacteria (1891) Eukaryota (32) Viruses (110) unclassified (3) Structure (11 ) Characterized (29)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 lysozyme (BA3501;BaGH25c) 3.2.1.17 Bacillus anthracis str. Ames AAP27267.1
NP_845781.1
Q81YN8 2WAG[A]
 bacteriolytic enzyme (PlyPH;BA2805) 3.2.1.17 Bacillus anthracis str. Ames AAP26640.1
NP_845154.1
Q81PJ7  
 lysozyme CH (CAC0554) 3.2.1.17 Clostridium acetobutylicum ATCC 824 AAA23250.1
AAK78533.1
NP_347193.1
P34020  
 lysozyme (CPE1314) 3.2.1.17 Clostridium perfringens str. 13 BAB81020.1
NP_562230.1
O06496  
 N-acetylmuramidase (AtlC;EF1992) 3.2.1.17 Enterococcus faecalis V583 AAO81737.1
AAR58131.1
NP_815667.1
Q833G2  
 N-acetylmuramidase (AtlB;EF0355) 3.2.1.17 Enterococcus faecalis V583 AAO80218.1
NP_814147.1
Q838S8  
 cell wall lytic enzyme (LysA) 3.2.1.17 Lactobacillus fermentum BR11 AAS57574.1 Q64J93  
 lysozyme (LysL) 3.2.1.17 Lactococcus lactis subsp. lactis CAA10710.1 Q9ZEK6  
 autolysin (AtlA) 3.2.1.17 Streptococcus criceti E49 BAH11115.1 B7X9H1  
 autolysin (AmL) 3.2.1.17 Streptococcus mutans C67-1 BAF03559.1 Q0KK88  
 1,4-β-N-acetylmuramidase (LytC) 3.2.1.17 Streptococcus pneumoniae M31 CAA08765.1
AAQ38109.1
AAY71755.1
Q9Z4J8  
 autolytic lysozyme (LytC;spr1431) 3.2.1.17 Streptococcus pneumoniae R6 AAL00235.1 Q8DP07 2WW5[A]
2WWC[A]
2WWD[A]
 lysozyme (Cellosyl) 3.2.1.17 Streptomyces coelicolor MULLER     1JFX[A]
 lysozyme CH / M1 3.2.1.17 Streptomyces globisporus AAA26687.1 P25310  
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 lysozyme (AN6470.2) 3.2.1.17 Aspergillus nidulans FGSC A4 EAA58492.1
ABF50879.1
C8V058
Q5AZ10
 
 lysozyme CH 3.2.1.17 Chalara sp.   P00721  
 lysozyme 1 (EHI_199110) 3.2.1.17 Entamoeba histolytica HM-1:IMSS EAL47908.1
CAA60916.1
   
Viruses
Protein Name EC#OrganismGenBankUniprotPDB/3D
 muramidase / endolysin (Psm;CPR_C0050) 3.2.1.17 Clostridium perfringens SM101 ABG87925.1 Q0SPG7 4KRT[A,B]
4KRU[A]
 endolysin (Mur-LH) 3.2.1.17 Lactobacillus helveticus phage f-0303 AAQ06663.1 Q71JA9  
 endolysin (Mur) 3.2.1.17 Lactobacillus phage LL-H AAC00557.1 Q38359  
 lysozyme CH 3.2.1.17 Lactobacillus phage mv1 AAA32264.1 P33486  
 lysin (Lys) 3.2.1.17 Lactobacillus phage phiadh CAB52540.1
NP_050170.1
Q38317  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 lysozyme 3.2.1.17 Leuconostoc phage 10MC AAD02486.1 Q9ZXB5  
 peptidoglycan endolysin 3.2.1.17 Streptococcus phage B30 AAN28166.2 Q8HA43  
 lysozyme (Cpl1;Cpl-1) 3.2.1.17 Streptococcus phage Cp-1 AAA32204.1
CAA87744.1
NP_044837.1
P15057 1H09[A]
1OBA[A]
2IXU[A]
2IXV[A]
2J8F[A]
2J8G[A]
 lysozyme (Cpl-7) 3.2.1.17 Streptococcus phage CP-7 AAA72844.1 P19385  
 lysozyme 3.2.1.17 Streptococcus phage CP-9 AAA72845.1 P19386  
 lysin (PlyB) 3.2.1.17 unidentified phage BcpI     2NW0[B]
2NW0[A]
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Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2014-10-14 © Copyright 1998-2014
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