Activities in Family	Lysozyme (EC 3.2.1.17);
Mechanism	Inverting e
Clan	GH-I
3D Structure Status	lysozyme fold
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Glu
External resources	CAZypedia; PRINTS;
Statistics	GenBank accession (26014); Uniprot accession (23); PDB accession (683); 3D entries (14); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
ABUW_1326		Acinetobacter baumannii AB5075-UW	AKA31074.1		6ET6[A] 1.20
muramidase (SpmX; EM6_0389)	3.2.1.17	Asticcacaulis excentricus M6	BBF79816.1	A0A3G9FZN7	6H9D[A,B,C] 1.90
lysozyme (DLP12;b0555;EO53_15490)	3.2.1.17	Escherichia coli str. K-12 substr. MG1655	AIZ92304.1 AAB40751.1 AAC73656.1 ALI41640.1 AMC97790.1 AUG15343.1 AVI55088.1 AYG20320.1	P78285	4ZPU[A,B,C,D] 2.40
STM3605 (fragment)		Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	AAL22465.1 NP_462506.1		4EVX[A,B] 1.70
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
muramidase (TsCWBD-GH24)	3.2.1.17	Trichophaea saccata CBS804.70	WJZ50377.1		8B2S[A,B] 1.94
Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
endolysin	3.2.1.17	Acinetobacter phage AbTZA1	AZU98615.1		8APP[A,B,C,D] 1.82
endolysin R21		Enterobacteria phage P21			3HDE[B,C,D] 1.95 3HDF[A,B] 1.70 3HDE[A] 1.95
lysozyme (ECTP15_02508;RrrD)	3.2.1.17	Escherichia coli O157 typing phage 15	AKE47249.1	A0A0F6R9G3	7M5I[A,B] 1.71
endolysin		Escherichia phage PBEC131	UNY67723.1		8HP8[A,B,C] 2.40
lysozyme (P22Lyso)	3.2.1.17	Lederbergvirus P22 ATCC 19585-B1	AAA32266.1 AAA88340.1 AAF75040.1 AAM81442.1 BAF80780.1 DAA01040.1 NP_059622.1	A8CGF4 P09963 P09963	2ANV[A,B] 1.04 2ANX[A,B] 1.04
peptidoglycan hydrolase (Gp36;Gp36C;KMV36C)		Pseudomonas phage phiKMV	CAD44227.1		cryst
lysozyme (LysA;Liz;Gp17)	3.2.1.17	Punavirus P1	AAD20630.1 AAQ13989.1 AAQ14097.1 CAA61013.1	Q37875 Q71TF3	1XJT[A] 1.75 1XJU[A,B] 1.07
tail-associated lysozyme (Gp5)	3.2.1.17	Tequatrovirus T4	AAD42482.1 CAA33749.1 NP_049757.1 QPI17370.1	A0A7S9SVH6 D9IEH9 P16009	1K28[A] 2.90 1PDL[A,B,C] 12.00 1WTH[A] 2.80 2Z6B[A] 3.11
lysozyme E (T4L;T4p123)	3.2.1.17	Tequatrovirus T4	AAD42568.1 CAA28212.1 NP_049736.1	D9IEF7 D9IEF7 P00720	102L[A] 1.74 103L[A] 1.90 104L[A,B] 2.80 107L[A] 1.80 108L[A] 1.80 109L[A] 1.85 110L[A] 1.70 111L[A] 1.80 112L[A] 1.80 113L[A] 1.80 114L[A] 1.80 115L[A] 1.80 118L[A] 1.80 119L[A] 1.65 120L[A] 1.80 122L[A] 1.80 123L[A] 1.80 125L[A] 1.85 126L[A] 1.80 127L[A] 1.85 128L[A] 1.70 129L[A] 1.70 130L[A] 1.70 131L[A] 1.70 137L[A,B] 1.85 138L[A] 1.70 139L[A] 1.70 140L[A] 2.10 141L[A] 2.00 142L[A] 2.00 143L[A] 2.00 144L[A] 2.10 145L[A] 2.00 146L[A] 1.85 147L[A] 2.00 148L[E] β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-α-D-GlcpNAc-(1-4)-GLU 1.90 149L[A] 2.60 150L[A,B,C,D] 2.20 151L[A] 2.20 152L[A] 2.00 155L[A] 1.85 156L[A] 1.80 157L[A] 1.85 158L[A] 1.80 159L[A] 1.80 160L[A] 1.80 161L[A] 1.70 162L[A] 1.80 163L[A] 1.80 164L[A] 1.80 165L[A] 1.75 166L[A] 1.75 167L[A,B] 2.20 168L[A,B,C,D,E] 2.90 169L[A,B,C,D,E] 3.00 170L[A] 2.60 171L[A] 2.50 172L[A] 1.90 173L[A] 1.70 174L[A,B] 2.30 175L[A,B] 2.10 176L[A,B] 2.20 177L[A] 2.50 178L[A] 2.71 179L[A] 2.70 180L[A] 1.75 181L[A] 1.80 182L[A] 1.80 183L[A] 1.80 184L[A] 1.80 185L[A] 1.80 186L[A] 1.80 187L[A] 1.80 188L[A] 1.80 189L[A] 2.50 190L[A] 2.00 191L[A] 1.95 192L[A] 1.90 195L[A] 1.90 196L[A] 2.30 197L[A] 2.10 198L[A] 2.00 199L[A] 1.85 1B6I[A] 1.90 1C60[A] 2.00 1C61[A] 2.00 1C62[A] 2.30 1C63[A] 2.00 1C64[A] 2.00 1C65[A] 2.00 1C66[A] 2.10 1C67[A] 2.20 1C68[A] 2.50 1C69[A] 1.80 1C6A[A] 2.10 1C6B[A] 2.20 1C6C[A] 2.00 1C6D[A] 2.00 1C6E[A] 1.90 1C6F[A] 2.00 1C6G[A] 1.90 1C6H[A] 1.90 1C6I[A] 1.90 1C6J[A] 1.90 1C6K[A] 1.90 1C6L[A] 1.90 1C6M[A] 2.10 1C6N[A] 2.20 1C6P[A] 1.90 1C6Q[A] 1.90 1C6T[A] 2.00 1CTW[A] 2.10 1CU0[A] 2.20 1CU2[A] 1.85 1CU3[A] 2.12 1CU5[A] 2.05 1CU6[A] 2.10 1CUP[A] 1.89 1CUQ[A] 2.05 1CV0[A] 2.12 1CV1[A] 2.10 1CV3[A] 1.80 1CV4[A] 1.90 1CV5[A] 1.87 1CV6[A] 1.90 1CVK[A] 1.80 1CX6[A] 2.01 1CX7[A] 1.94 1D2W[A] 1.89 1D2Y[A] 2.06 1D3F[A] 2.05 1D3J[A] 1.97 1D3M[A] 2.12 1D3N[A] 2.00 1D9W[A] 1.91 1DYA[A] 1.90 1DYB[A] 1.75 1DYC[A] 2.10 1DYD[A] 2.10 1DYE[A] 1.80 1DYF[A] 1.90 1DYG[A] 2.10 1EPY[A] 1.85 1G06[A] 1.85 1G07[A] 1.70 1G0G[A] 1.90 1G0J[A] 1.80 1G0K[A] 1.85 1G0L[A] 1.80 1G0M[A] 1.70 1G0P[A] 1.80 1G0Q[A] 1.80 1JOZ[A] 1.80 1JQU[A,B,C,D] 2.60 1JTM[A] 1.90 1JTN[A,B] 2.30 1KNI[A] 1.70 1KS3[A] 2.16 1KW5[A] 1.75 1KW7[A] 1.89 1KY0[A] 1.97 1KY1[A] 2.05 1L00[A] 1.90 1L01[A] 1.70 1L02[A] 1.70 1L03[A] 1.70 1L04[A] 1.70 1L05[A] 1.70 1L06[A] 1.70 1L07[A] 1.70 1L08[A] 1.70 1L09[A] 1.70 1L0J[A] 1.98 1L0K[A] 2.02 1L10[A] 1.70 1L11[A] 1.70 1L12[A] 1.70 1L13[A] 1.70 1L15[A] 1.70 1L16[A] 1.70 1L17[A] 1.70 1L18[A] 1.70 1L19[A] 1.70 1L20[A] 1.85 1L21[A] 1.85 1L22[A] 1.70 1L23[A] 1.70 1L24[A] 1.70 1L25[A] 1.80 1L26[A] 1.70 1L27[A] 1.80 1L28[A] 1.90 1L29[A] 1.70 1L30[A] 1.70 1L31[A] 1.80 1L32[A] 1.70 1L33[A] 1.70 1L34[A] 1.90 1L35[A] 1.80 1L36[A] 1.70 1L37[A] 1.85 1L38[A] 1.80 1L39[A] 1.85 1L40[A] 1.85 1L41[A] 1.75 1L42[A] 1.80 1L43[A] 1.80 1L44[A] 1.70 1L45[A] 1.70 1L46[A] 1.70 1L47[A] 1.70 1L48[A] 1.70 1L49[A] 1.80 1L50[A] 1.85 1L51[A] 1.90 1L52[A] 1.70 1L53[A] 1.85 1L54[A] 1.90 1L55[A] 1.90 1L56[A] 1.80 1L57[A] 1.90 1L58[A] 1.65 1L59[A] 1.75 1L60[A] 1.70 1L61[A] 1.80 1L62[A] 1.70 1L63[A] 1.75 1L64[A] 1.90 1L65[A] 1.70 1L66[A] 1.70 1L67[A] 1.90 1L68[A] 1.70 1L69[A] 1.90 1L70[A] 1.90 1L71[A] 1.85 1L72[A] 1.85 1L73[A] 1.85 1L74[A] 1.70 1L75[A] 1.90 1L76[A] 1.90 1L77[A] 2.05 1L79[A] 1.90 1L80[A] 1.80 1L81[A] 2.00 1L82[A] 2.10 1L83[A] 1.70 1L84[A] 1.90 1L85[A] 2.00 1L86[A] 1.80 1L87[A] 1.80 1L88[A] 1.85 1L89[A] 1.90 1L90[A] 1.75 1L91[A] 1.80 1L92[A] 1.70 1L93[A] 1.80 1L94[A] 1.80 1L95[A] 2.00 1L96[A] 2.00 1L97[A,B] 2.00 1L98[A] 1.80 1L99[A] 1.95 1LGU[A] 1.90 1LGW[A] 1.85 1LGX[A] 1.90 1LI2[A] 2.00 1LI3[A] 1.85 1LI6[A] 2.00 1LLH[A] 1.80 1LPY[A] 1.65 1LW9[A] 1.45 1LWG[A] 1.70 1LWK[A] 2.10 1LYD[A] 2.00 1LYE[A] 1.80 1LYF[A] 1.80 1LYG[A] 1.80 1LYH[A] 1.70 1LYI[A] 2.00 1LYJ[A] 1.80 1NHB[A] 1.80 1OV5[A] 2.10 1OV7[A] 2.00 1OVH[A] 1.95 1OVJ[A] 2.00 1OVK[A] 2.10 1OWY[A] 1.90 1OWZ[A] 1.90 1P2L[A] 1.58 1P2R[A] 1.58 1P37[A] 1.57 1P46[A] 1.67 1P56[A] 1.80 1P5C[A,B,C,D] 2.50 1P64[A] 1.62 1P6Y[A] 1.54 1P7S[A] 1.50 1QS5[A] 2.50 1QS9[A] 1.85 1QSB[A] 1.80 1QSQ[A] 1.90 1QT3[A] 1.85 1QT4[A] 2.10 1QT5[A] 1.80 1QT6[A] 1.90 1QT7[A] 1.80 1QT8[A] 1.90 1QTB[A] 1.90 1QTC[A] 2.50 1QTD[A] 2.50 1QTH[A,B] 1.90 1QTV[A] 2.30 1QTZ[A] 2.00 1QUD[A] 1.75 1QUG[A] 1.90 1QUH[A] 1.85 1QUO[A] 1.90 1SWY[A] 1.06 1SWZ[A] 1.06 1SX2[A] 1.06 1SX7[A] 1.06 1T6H[A] 2.01 1T8A[A] 2.00 1T97[A,B] 2.70 1TLA[A] 2.00 1XEP[A] 1.55 1ZUR[A] 1.60 1ZWN[A] 1.80 1ZYT[A] 1.70 200L[A] 1.95 201L[A,B] 2.00 205L[A] 2.10 206L[A] 1.75 209L[A] 2.70 210L[A] 1.89 211L[A] 1.70 212L[A] 1.76 213L[A] 2.13 214L[A] 1.89 215L[A] 1.96 216L[A,B] 2.10 217L[A] 1.70 218L[A] 2.05 219L[A] 1.66 220L[A] 1.85 221L[A] 1.70 222L[A] 1.90 223L[A] 1.90 224L[A] 1.85 225L[A] 1.90 226L[A] 1.80 227L[A] 2.00 228L[A] 1.90 229L[A] 1.80 230L[A] 1.90 231L[A] 2.50 232L[A] 1.73 233L[A] 1.90 234L[A] 1.90 235L[A] 1.90 236L[A] 1.90 237L[A] 1.70 238L[A] 1.80 239L[A] 1.80 240L[A] 1.75 241L[A] 1.70 242L[A] 1.80 243L[A] 1.75 244L[A] 1.70 245L[A] 1.80 246L[A] 1.80 247L[A] 1.75 248L[A] 1.90 249L[A] 1.90 250L[A] 1.80 251L[A] 2.60 252L[A] 2.10 253L[A] 2.00 254L[A] 1.90 255L[A] 1.80 256L[A] 1.80 257L[A] 1.90 258L[A] 1.80 259L[A] 1.92 260L[A] 1.80 261L[A] 2.50 262L[A,B] 2.50 2A4T[A] 1.70 2B6T[A] 2.10 2B6W[A] 2.20 2B6X[A] 2.11 2B6Y[A] 2.40 2B6Z[A] 2.40 2B70[A] 2.40 2B72[A] 2.10 2B73[A] 2.15 2B74[A] 2.10 2B75[A] 2.10 2B7W[A,B,C,D] 3.00 2B7X[A,B,C,D] 3.00 2CUU[A] 1.75 2F2Q[A] 1.45 2F32[A] 1.80 2F47[A] 1.70 2HUK[A] 2.00 2HUL[A] 1.80 2HUM[A,B] 2.35 2IGC[A] 1.40 2L78[A] 2.00 2LC9[A] NMR 2LCB[A] NMR 2LZM[A] 1.70 2NTG[A] 1.40 2NTH[A] 1.80 2NZB[A] 1.64 2NZK[A] 1.80 2NZN[A] 1.68 2O4W[A] 1.90 2O79[A] 1.80 2OE4[X] 2.10 2OE7[X] 2.10 2OE9[X] 2.01 2OEA[X] 2.01 2OTY[X] 1.83 2OTZ[X] 2.07 2OU0[X] 1.94 2OU8[A] 1.80 2OU9[A] 1.55 2Q9D[A] 1.40 2Q9E[A,B,C] 2.10 2QAR[C,F] 2.40 2QB0[B,D] 2.56 2RAY[X] 1.80 2RAZ[X] 1.64 2RB0[X] 1.84 2RB1[X] 1.70 2RB2[X] 1.46 2RBN[A] 1.29 2RBO[A] 1.29 2RBP[A] 1.47 2RBQ[A] 1.63 2RBR[A] 1.43 2RBS[A] 1.56 2RH1[A] α-D-Glcp-(1-4)-β-D-Glcp 2.40 3C7W[A] 1.77 3C7Y[A] 1.95 3C7Z[A] 1.67 3C80[A] 1.99 3C81[A] 1.85 3C82[A] 1.68 3C83[A] 1.84 3C8Q[A] 1.64 3C8R[A] 1.80 3C8S[A] 1.68 3CDO[A,B,C,D] 1.87 3CDQ[A] 1.68 3CDR[A] 1.70 3CDT[A] 1.63 3CDV[A] 1.73 3D4S[A] 2.80 3DKE[X] 1.25 3DMV[A] 1.65 3DMX[A] 1.80 3DMZ[A] 2.00 3DN0[A] 1.80 3DN1[A] 1.80 3DN2[A] 1.80 3DN3[A] 1.80 3DN4[A] 1.80 3DN6[A] 1.80 3DN8[A] 1.70 3DNA[A] 1.70 3EML[A] 2.60 3F8V[A] 1.08 3F9L[A] 1.19 3FA0[A] 1.09 3FAD[A] 1.20 3FI5[A,B,C,D] 1.53 3G3V[A] 2.10 3G3W[A] 2.30 3G3X[A] 1.80 3GUI[A] 1.45 3GUJ[A] 1.60 3GUK[A,B] 1.85 3GUL[A,B] 2.07 3GUM[A,B] 2.24 3GUN[A,B] 1.50 3GUO[A,B] 2.16 3GUP[A,B] 1.50 3HH3[A] 1.25 3HH4[A] 1.25 3HH5[A] 1.25 3HH6[A] 1.25 3HT6[A] 1.59 3HT7[A] 1.70 3HT8[A] 1.60 3HT9[A] 2.02 3HTB[A] 1.81 3HTD[A] 1.40 3HTF[A] 1.85 3HTG[A] 1.26 3HU8[A] 1.80 3HU9[A] 1.46 3HUA[A] 1.40 3HUK[A] 1.29 3HUQ[A] 1.45 3HWL[A] 1.80 3JR6[A,B,C,D] 3.00 3K2R[A] 1.50 3L2X[A] 1.80 3L64[A] 1.90 3LZM[A] 1.70 3NY8[A] 2.84 3ODU[A,B] 2.50 3OE0[A] 2.90 3OE6[A] 3.20 3OE8[A,B,C] 3.10 3OE9[A,B] 3.10 3P0G[A] 3.50 3PBL[A,B] α-D-Glcp-(1-4)-β-D-Glcp 2.89 3PDS[A] 3.50 3QAK[A] 2.71 3RUN[A] α-L-2-deoxy-Fucp3N-(1-2)-β-D-Glcp-(1-1)-<non_carb> 1.40 3RZE[A] 3.10 3SB5[A,B,C,D] 2.46 3SB6[A,B] 2.70 3SB7[A,B] 2.70 3SB8[A,B,C] 2.65 3SB9[A,B] 2.45 3SBA[A,B,C,D,E,F] 2.75 3SBB[C] 1.43 3UON[A] β-D-Glcp 3.00 3V2W[A] 3.35 3V2Y[A] 2.80 3VW7[A] 2.20 4ARJ[A,B] 2.59 4DAJ[A,B,C,D] 3.40 4DJH[A,B] 2.90 4DKL[A] 2.80 4E97[A,B] 1.30 4EJ4[A] 3.40 4EKP[A,B] 1.64 4EKQ[A,B] 1.54 4EKR[A,B] 1.49 4EKS[A,B] 1.64 4EPI[A] 1.74 4EXM[A,B,C,D] 2.60 4GBR[B] 3.99 4GRV[A] 2.80 4HTT[A,B] 6.80 4I7J[A,B] 1.67 4I7K[A,B] 1.72 4I7L[A,B] 1.52 4I7M[A,B] 1.48 4I7N[A,B] 1.58 4I7O[A,B] 1.73 4I7P[A,B] 1.60 4I7Q[A,B] 1.58 4I7R[A,B] 1.52 4I7S[A,B] 1.69 4I7T[A,B] 1.55 4IAP[A,B] 2.30 4K5Y[A,B,C] 2.98 4LDE[A] 2.79 4LDL[A] 3.10 4LDO[A] 3.20 4LZM[A] 1.70 4N9N[A,B] 2.90 4OO9[A] 2.60 4PHU[A] 2.33 4PJZ[A] 1.87 4PK0[A] 2.30 4PLA[A] 2.77 4QKX[A] 3.30 4RWS[A] 3.10 4S0W[A,B] 2.12 4U14[A] 3.57 4U15[A,B] 2.80 4U16[A,B] 3.70 4W51[A] 1.45 4W52[A] 1.50 4W53[A] 1.56 4W54[A] 1.79 4W55[A] 1.64 4W56[A] 1.63 4W57[A] 1.68 4W58[A] 1.80 4W59[A] 1.39 4W8F[A,B] 3.54 4WTV[A,B] 1.90 4XEE[A] 2.90 4XES[A] 2.60 4YC4[A] 2.58 4YX7[C,F] 2.00 4YXA[C,F] 2.35 4YXC[A] 2.30 5CXV[A] 2.70 5D5A[A] α-D-Glcp-(1-4)-β-D-Glcp 2.48 5D5B[A] α-D-Glcp-(1-4)-β-D-Glcp 3.80 5DGY[A,B,C,D] 7.70 5DSG[A,B] 2.60 5EE7[A] 2.50 5EUT[A] 2.80 5EWX[A,B] 2.60 5G27[A] 1.61 5I0N[A] 2.28 5I14[A,B] 1.75 5JDT[A] 1.00 5JGN[A] 1.53 5JGR[A] 1.46 5JGU[A] 1.47 5JGV[A] 1.73 5JGX[A] 1.53 5JGZ[A] 1.53 5JWS[A] 1.65 5JWT[A] 1.41 5KGR[A] 1.47 5KHZ[A] 1.49 5KI1[A] 1.46 5KI2[A] 1.50 5KI3[A] 1.65 5KI8[A] 1.55 5KIG[A] 1.50 5KII[A] 1.56 5KIM[A] 1.50 5KIO[A] 1.63 5LWO[A] 1.18 5LZM[A] 1.80 5NDD[A] 2.80 5NDZ[A] 3.60 5V7D[A] 1.35 5V7E[A] 1.36 5V7F[A] 1.65 5V83[A] 2.00 5V86[A] 1.37 5V88[A] 1.60 5VEW[A,B] 2.70 5VEX[A,B] 3.00 5VNQ[A] 2.20 5VNR[A] 1.63 5XEZ[A,B] 3.00 5XF1[A,B] 3.19 5XPE[A] 1.65 5XPF[A] 1.04 6LZM[A] 1.80 6PGY[A] 2.00 6U0B[A] 1.95 6U0C[A] 2.00 6U0E[A] 2.11 6U0F[A] 2.05 6V51[A] 1.50 7DWS[A,B,C] 2.80 7LOA[A] 1.07 7LOB[A] 1.10 7LOC[A] 1.16 7LOD[A] 1.02 7LOE[A] 1.01 7LOF[A] 1.05 7LOJ[A] 1.50 7LX6[A] 1.05 7LX7[A] 1.05 7LX8[A] 1.03 7LX9[A] 1.19 7LZM[A] 1.80
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