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Glycoside Hydrolase Family 23

Activities in FamilyChitinase (EC 3.2.1.14);
Lysozyme (EC 3.2.1.17);
Peptidoglycan lytic transglycosylase / peptidoglycan lyase (EC 4.2.2.29);
Mechanism Unknown e
3D Structure Statuslysozyme fold
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
NoteCorresponds to family 1 of the peptidoglycan lytic transglycosylases described by N.T. Blackburn and A.J. Clarke (2001) J. Mol. Evol. 52, 78-84; Note that 'peptidoglycan lytic transglycosylases' cleave peptidoglycan without intervention of a water molecule.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (127144); Uniprot accession (57); PDB accession (88); 3D entries (21); cryst (0)
Summary
Download GH23 (125873) Taxonomic display Structure (21) Characterized (33)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 DM_29   Erwinia phage vB_EamM_Deimos-Minion ANH52127.1    
 DESERTFOX_29   Erwinia phage vB_EamM_Desertfox AUG86137.1    
 EARLPHILLIPIV_215   Erwinia phage vB_EamM_EarlPhillipIV ANZ49064.1    
 EARLPHILLIPIV_185   Erwinia phage vB_EamM_EarlPhillipIV ANZ49034.1    
 HUXLEY_251   Erwinia phage vB_EamM_Huxley ANZ49333.1    
 JOAD_104   Erwinia phage vB_EamM_Joad ASU03811.1    
 KWAN_223   Erwinia phage vB_EamM_Kwan ANZ49575.1    
 KWAN_265   Erwinia phage vB_EamM_Kwan ANZ49617.1    
 MADMEL_29   Erwinia phage vB_EamM_MadMel AUG86457.1    
 MORTIMER_29   Erwinia phage vB_EamM_Mortimer AUG86778.1    
 PARSHIK_252   Erwinia phage vB_EamM_Parshik ANZ50161.1    
 PHOBOS_221   Erwinia phage vB_EamM_Phobos ANZ50411.1    
 PHOBOS_192   Erwinia phage vB_EamM_Phobos ANZ50382.1    
 RAY_29   Erwinia phage vB_EamM_RAY ANH51810.1    
 RISINGSUN_104   Erwinia phage vB_EamM_RisingSun ASU03566.1    
 SIMMY50_30   Erwinia phage vB_EamM_Simmy50 ANH51492.1    
 SPECIALG_29   Erwinia phage vB_EamM_Special G ANJ64839.1    
 STRATTON_220   Erwinia phage vB_EamM_Stratton ANZ50645.1    
 STRATTON_261   Erwinia phage vB_EamM_Stratton ANZ50686.1    
 TROPICALSUN_33   Erwinia phage vB_EamM_TropicalSun QEG13823.1    
 Y3_301   Erwinia phage vB_EamM_Y3 ARW58941.1    
 YOLOSWAG_297   Erwinia phage vB_EamM_Yoloswag AQT28766.1    
 internal virion protein D   Erwinia phage vB_EamP-L1 AEJ81509.1    
 ORF   Erwinia phage vB_Ea_2910A WAK44498.1    
 WELLINGTON_222   Erwinia phage Wellington AXF51348.1    
 WELLINGTON_265   Erwinia phage Wellington AXF51391.1    
 AS5_0046 (16)   Escherichia phage 13a ACF15927.1    
 1721_39   Escherichia phage 172-1 AJW61403.1    
 LXB_041 (16)   Escherichia phage 285P ACV32486.1    
 internal (core) protein   Escherichia phage 4E8 WJJ57305.1    
 protein inside capsid D   Escherichia phage 64795_ec1 ANM45763.1    
 APCJM32_29   Escherichia phage APC_JM3.2 ATN92735.1    
 peptidoglycan lytic exotransglycosylase   Escherichia phage AV103 WPK33031.1    
 internal (core) protein   Escherichia phage AV128 WPK38498.1    
 AS7_0045 (16)   Escherichia phage BA14 ACF15769.1    
 1302_0034   Escherichia phage C130_2 AXC34344.1    
 internal virion protein   Escherichia phage C5 AYD80208.1    
 car1b_043 (fragment)   Escherichia phage Carena WPJ67456.1    
 bas66_0048   Escherichia phage CarlSpitteler Bas68 QXV76843.1    
 internal virion protein D   Escherichia phage CICC 80001 AIM41098.1    
 internal (core) protein   Escherichia phage E20-1 UYE89925.1    
 internal virion protein D   Escherichia phage Ebrios AVJ51924.1    
 internal (core) protein   Escherichia phage ECA2 ANN86231.1    
 soluble lytic murein transglycosylase   Escherichia phage ECML-117 AFO10488.1    
 ECML606-1_000011   Escherichia phage ECML-606-1 WCD43962.1    
 ECML606-1_000023   Escherichia phage ECML-606-1 WCD43974.1    
 ECO71P1_00058 (VII)   Escherichia phage ECO71P1 WAX14121.1    
 ORF   Escherichia phage Ecp_YSF WMM91810.1    
 internal virion protein D   Escherichia phage EG1 ATW57754.1    
 catalytic lytic transglycosylase   Escherichia phage EK010 BCG45025.1    
 ORF   Escherichia phage EP335 AVZ45103.1    
 bas67_0047   Escherichia phage ErnstBeyeler Bas67 QXV78440.1    
 ES17_21   Escherichia phage ES17 QPL11066.1    
 F13_0062   Escherichia phage F13 WAQ79348.1    
 soluble lytic murein transglycosylase   Escherichia phage FEC19 AYD85487.1    
 flopper_39   Escherichia phage flopper QHR68781.1    
 internal virion protein   Escherichia phage FS2B UAG58404.1    
 HZ2R8_37   Escherichia phage HZ2R8 AUV62661.1    
 internal core protein   Escherichia phage IME267 QYC96899.1    
 bas65_0049   Escherichia phage JacobBurckhardt Bas65 QXV80674.1    
 ORF   Escherichia phage JB01 QOV06365.1    
 bas64_0050   Escherichia phage JeanTinguely Bas64 QXV80899.1    
 JL22_gp022 (SiT)   Escherichia phage JL22 UOL50990.1    
 internal virion protein D   Escherichia phage K30 AEH41054.1    
 ECBP2_0020   Escherichia phage KBNP135 AFR52053.1    
 ECBP3_0020   Escherichia phage KBNP1711 AHI60797.1    
 phiL_022   Escherichia phage LAMP AUM57603.1    
 LL2_043   Escherichia phage LL2 AXY85361.1    
 Mangalitsa_068   Escherichia phage Mangalitsa QEG07870.1    
 CPT_Mansfield_045   Escherichia phage Mansfield QEG09870.1    
 ORF   Escherichia phage MLP1 UEN68347.1    
 protein inside capsid D   Escherichia phage MLP3 UEN68525.1    
 MN03_00028   Escherichia phage MN03 QIN95696.1    
 MN05_00015   Escherichia phage MN05 QIN96080.1    
 PSH1131_009   Escherichia phage myPSH1131 AVQ10014.1    
 PSH2311_015   Escherichia phage myPSH2311 AVP40112.1    
 internal virion protein   Escherichia phage N13 AYD80252.1    
 internal virion protein   Escherichia phage N30 AYD80162.1    
 protein inside capsid D   Escherichia phage NC-A QBG78754.1    
 internal virion protein   Escherichia phage O18-011 BCG45077.1    
 PLNCDLJO_00035 (SiT)   Escherichia phage P1 UYD72437.1    
 internal virion protein with endolysin domain   Escherichia phage P151 WVW36876.1    
 ZD95_41   Escherichia phage P1723 QKM75970.1    
 P483_4   Escherichia phage P483 AJF40439.1    
 P694_49   Escherichia phage P694 AJF40529.1    
 CPT_Paul_020   Escherichia phage Paul QEG08116.1    
 internal (core) protein   Escherichia phage pEC-N1203-2Af.1 WIW36227.1    
 internal (core) protein   Escherichia phage PGN6866 QKL16994.1    
 PGT2_g00039   Escherichia phage PGT2 ATS92457.1    
 internal virion protein with endolysin domain   Escherichia phage PGX1 WGL32443.1    
 Sit   Escherichia phage phi456 WNL49372.1    
 putative tail fiber   Escherichia phage phiEcoM-GJ1 ABR68774.1    
 ORF   Escherichia phage phiEc_1 BEH83398.1    
 phiKT_00022   Escherichia phage phiKT AEZ65105.1    
 ORF   Escherichia phage PhiV-1 QLF85792.1    
 peptidoglycan lytic exotransglycosylase   Escherichia phage pO103 WMM35704.1    
 tail tube initiator protein   Escherichia phage PO103-1 UTQ80263.1    
 peptidoglycan lytic exotransglycosylase   Escherichia phage pO111 WMM35718.1    
 lytic transglycosylase   Escherichia phage Rac-SA53 ALP46865.1    
 transglycosylase   Escherichia phage SDYTW1-F1-2-2_3 WNL49186.1    
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