Glycoside Hydrolase Family 20

Activities in Familyβ-hexosaminidase (EC 3.2.1.52); lacto-N-biosidase (EC 3.2.1.140); β-1,6-N-acetylglucosaminidase) (EC 3.2.1.-); β-6-SO3-N-acetylglucosaminidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS; Tay-Sachs Disease;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4682); Uniprot accession (779); PDB accession (79); 3D entries (18); cryst (1)
All (4400) Archaea (4) Bacteria (4073) Eukaryota (312) Viruses (1) unclassified (10) Structure (18 - 1 cryst) Characterized (124)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-N-acetylglucosaminidase (Nag1) (probable fragment)   Paracoccidioides brasiliensis AAL14649.1
AAK94334.1
Q96US2
Q96VZ1
 
 ORF   Passalora fulva 0WU AQA29353.1    
 β-N-acetylhexosaminidase (NagA;Hex;Pen ch 20) 3.2.1.52 Penicillium chrysogenum AAF00010.1
AAP66194.1
AAQ80154.1
Q02352
Q9URR8
 
 β-N-acetylhexosaminidase (Hex;PoHex) 3.2.1.52 Penicillium oxalicum CCF 1959 / CCF 3438 ABY57948.1 E3NYM0  
 β-N-acetylglucosaminidase (Hex;NagA;Pc20g10360)   Penicillium rubens Wisconsin 54-1255 CAP86365.1 B6HFN5  
 Pc22g24800   Penicillium rubens Wisconsin 54-1255 CAP99768.1 B6HR95  
 family 20 glycoside hydrolase (fragment)   Phakopsora pachyrhizi ALL40661.1    
 ORF   Phallusia mammillata CAD57204.1 Q7YTB2  
 WS02743_M24   Picea sitchensis ABR16487.1 B8LLF7  
 chitobiase   Pinctada margaritifera CCE46157.1 H2A0L6  
 0_4885_01 (fragment)   Pinus radiata AEW07550.1    
 0_4885_01 (fragment)   Pinus taeda AFG46549.1
AFG46539.1
AFG46540.1
AFG46541.1
AFG46542.1
AFG46543.1
AFG46544.1
AFG46545.1
AFG46546.1
AFG46547.1
AFG46548.1
AFG46550.1
AFG46551.1
AFG46552.1
AFG46553.1
AFG46554.1
AFG46555.1
   
 Pa_1_9530   Podospora anserina S mat+ CAP69287.1
CDP23307.1
B2AY13  
 DKFZp459O0432   Pongo abelii CAH90623.1 Q5RC84  
 ORF   Portunus trituberculatus AHJ81101.1    
 ORF   Pristhesancus plagipennis AQM58348.1    
 β-hexosaminidase 1 (Hexo1)   Prunus persica AFP90754.1    
 β-hexosaminidase 2 (HEXO2)   Prunus persica AGC00493.1    
 β-hexosaminidase   Pyrus x bretschneideri AGR44467.1    
 Unknown (protein for MGC:94872)   Rattus norvegicus AAH79376.1 Q6AXR4  
 HexA (protein for MGC:95289)   Rattus norvegicus AAH82097.1 Q641X3  
 Unknown (protein for IMAGE:8371290)   Rattus norvegicus AAI58671.1 B0BN37  
 β-N-acetylhexosaminidase   Rhizomucor miehei CAU432 AKU79211.1    
 RHTO0S_01e10858g   Rhodotorula toruloides CECT1137 CDR35951.1    
 RHTO0S_01e15302g   Rhodotorula toruloides CECT1137 CDR36147.1    
 RHTO0S_01e10858g (fragment)   Rhodotorula toruloides CECT1137 CDR35952.1    
 ORF (fragment)   Riptortus pedestris BAN20808.1    
 ORF (fragment)   Riptortus pedestris BAN21503.1    
 β-hexosaminidase beta chain (HexB)   Salmo salar ACI33266.1 B5X1T5  
 β-hexosaminidase alpha chain (HexA)   Salmo salar ACI34159.1 B5X4C8  
 HexA (fragment)   Salmo salar ACI66373.1 B5X6A3  
 PICST_32069   Scheffersomyces stipitis CBS 6054 ABN66755.1
ABN66755.2
   
 β-hexosaminidase α-chain   Schistosoma japonicum CAX82416.1 C7TXU0  
 ORF   Schistosoma japonicum AAW26910.1
AAP05936.1
Q5DB96
Q86FD9
 
 SJCHGC04173 (fragment)   Schistosoma japonicum AAX26856.2 Q5C0G9  
 Smp_053900   Schistosoma mansoni Puerto Rico CAZ32919.1
CCD79912.1
C4QBS8  
 Smp_134300   Schistosoma mansoni Puerto Rico CAZ29931.1
CCD77137.1
C4Q395  
 sscle_01g003330   Sclerotinia sclerotiorum 1980 UF-70 APA05563.1    
 PIIN_04767   Serendipita indica DSM 11827 CCA70832.1    
 β-hexosaminidase 1 (β-Hex)   Solanum lycopersicum ABY83272.1
ABY83274.1
D3TI69  
 β-hexosaminidase 2   Solanum lycopersicum ABY83273.1    
 β-N-acetylglucosaminidase 3 (HexA;Hex;GlcNAcase3;SfGlcNAcase3) 3.2.1.52 Spodoptera frugiperda ABA27426.1
ABB76926.1
ABY57947.1
Q3LS76  
 β-N-acetylglucosaminidase 2 (HexB;Hex;SfHex) 3.2.1.52 Spodoptera frugiperda ABA27427.1
ABB76925.1
Q3LS75  
 β-N-acetylglucosaminidase 1 (GlcNAcase1;SfGlcNAcase1) 3.2.1.52 Spodoptera frugiperda ABB76924.1 Q2Q1D3  
 lysosomal β-N-acetylglucosaminidase   Spodoptera frugiperda BAN29056.1    
 processing β-N-acetylglucosaminidase (Fdl;SfFDL;Sf-Fdl) 3.2.1.52 Spodoptera frugiperda ACA30398.1 B1P868  
 ORF (fragment)   Spodoptera litura AGV76305.1    
 sr11178.2   Sporisorium reilianum SRZ2 CBQ73971.1    
 sr11983   Sporisorium reilianum SRZ2 CBQ68118.1    
 SPSC_01958   Sporisorium scitamineum SscI8 CDU23329.1    
 SPSC_00491   Sporisorium scitamineum SscI8 CDR87365.1    
 SRAE_X000164400   Strongyloides ratti ED321 Heterogonic CEF59901.1    
 SRAE_2000404900   Strongyloides ratti ED321 Heterogonic CEF69400.1    
 SRAE_1000198200   Strongyloides ratti ED321 Heterogonic CEF63724.1    
 SRAE_2000108200   Strongyloides ratti ED321 Heterogonic CEF66413.1    
 AWJ20_111   Sugiyamaella lignohabitans CBS 10342 ANB11885.1    
 β-N-acetylhexosaminidase (HexB) 3.2.1.52 Sus scrofa CAA63123.1
BAI47712.1
Q29548  
 hexosaminidase A (HexA)   Sus scrofa ACA43012.1 B1PK15  
 β-N-acetylhexosaminidase (HexTF) 3.2.1.52 Talaromyces flavus CCF2686 AEQ33603.1    
 β-hexosaminidase (Bhex) 3.2.1.52 Tetrahymena thermophila CAD55811.1 Q8IEV5  
 MYCTH_2294755   Thermothelomyces thermophila ATCC 42464 AEO53435.1    
 THITE_2121574   Thielavia terrestris NRRL 8126 AEO70312.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55611.1    
 secreted protein   Thraustotheca clavata ATCC 34112 AIG55750.1    
 hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (HexdC)   Tokudaia muenninki BAT46498.1    
 β-N-acetylglucosaminidase (Nag1)   Tribolium castaneum ABQ95982.1 A5YVX3  
 β-N-acetylglucosaminidase (Nag2)   Tribolium castaneum ABQ95983.1 A5YVX4  
 β-N-acetylglucosaminidase (Nag3)   Tribolium castaneum ABQ95984.1 A5YVX5  
 β-N-acetylglucosaminidase (Fdl)   Tribolium castaneum ABQ95985.1 A5YVX6  
 N-acetyl-β-D-glucosaminidase (Nag1)   Trichoderma atroviride ATCC 74015 AAT70229.1 Q6IYG0  
 N-acetyl-β-D-glucosaminidase (Nag1)   Trichoderma atroviride ATCC 74016 AAT42222.1 Q6IYG0  
 N-acetyl-β-D-glucosaminidase (Nag1)   Trichoderma atroviride ATCC 74018 AAT70228.1 Q6IYG0  
 β-N-acetylglucosaminidase (Nag2;TRIATDRAFT_41039) 3.2.1.52 Trichoderma atroviride IMI 206040 EHK46127.1    
 β-N-acetylglucosaminidase (Nag1;Nag70;Chit73) 3.2.1.52 Trichoderma atroviride P1 AAB50829.1 P87258  
 β-N-acetylglucosaminidase (Nag2) (fragment) 3.2.1.52 Trichoderma atroviride P1 ABC95196.1 Q0ZLH7  
 β-N-acetylglucosaminidase (Nag)   Trichoderma hamatum GD12 AEM46056.1    
 exo-chitinase 1 (Exc1) 3.2.1.52 Trichoderma harzianum AAB47060.1 P78738  
 exo-chitinase 2 (Exc2) 3.2.1.52 Trichoderma harzianum AAB47061.1 P78739  
 hexosaminidase (Exc1y) 3.2.1.52 Trichoderma harzianum T-Y CAC85402.1 Q8NIN7  
 hexosaminidase (Exc2y) 3.2.1.52 Trichoderma harzianum T-Y CAC85401.1 Q8NIN6  
 TRIREDRAFT_23346 (Nag2)   Trichoderma reesei QM6a EGR44872.1    
 β-N-acetylglucosaminidase (Nag1;TRIREDRAFT_21725) 3.2.1.52 Trichoderma reesei QM6a / RutC30?U3 EGR50812.1    
 exochitinase (ExoChi)   Trichoderma saturnisporum ADB89218.1 D3JTC5  
 Nag1   Trichoderma virens AAL78815.1
AAL84700.1
ACJ09606.1
Q8TFA8  
 chitobiase (Nag2)   Trichoderma virens AAL84701.1 Q8TG95  
 β-N-acetylglucosaminidase (Nag1)   Trichoderma virens T.v.223 AFD36224.1    
 β-N-acetylhexosaminidase (Nag2)   Trichoderma virens T.v.223 AFD36225.1    
 β-N-acetylglucosaminidase   Trichoplusia ni AAL82580.1
ABH09730.1
ABH09731.1
Q8T4N1  
 fused lobes (FdL)   Trichoplusia ni ACV89845.1 D3GGI7  
 TRAES_3BF032000090CFD_c1   Triticum aestivum CDM85418.1    
 UBRO_05562   Ustilago bromivora UB2112 SAM83458.1    
 UBRO_01069   Ustilago bromivora UB2112 SAM59527.1    
 exochitinase   Ustilago maydis UM521 CAC59704.1
CAC41659.1
Q96VD9
Q96VF2
 
 VIGAN_08011600 (Vigan.08g011600)   Vigna angularis var. angularis BAT93601.1    
 VIGAN_07197900 (Vigan.07g197900)   Vigna angularis var. angularis BAT93082.1    
 VIGAN_07200800 (Vigan.07g200800)   Vigna angularis var. angularis BAT93106.1    
 VIGAN_04018100 (Vigan.04g018100) (fragment)   Vigna angularis var. angularis BAT83080.1    
 VITISV_034316   Vitis vinifera CAN76146.1 A5AX89  
 Unknown (IMAGE:8821228)   Xenopus laevis AAI59343.1
AEJ87970.1
B0JZW3  
 ORF LOC548664 (fragment)   Xenopus tropicalis AAI18694.1 Q0VFU8  
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