Glycoside Hydrolase Family 20

Activities in Familyβ-hexosaminidase (EC 3.2.1.52); lacto-N-biosidase (EC 3.2.1.140); β-1,6-N-acetylglucosaminidase) (EC 3.2.1.-); β-6-SO3-N-acetylglucosaminidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS; Tay-Sachs Disease;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4551); Uniprot accession (779); PDB accession (79); 3D entries (18); cryst (1)
All (4268) Archaea (4) Bacteria (3943) Eukaryota (310) Viruses (1) unclassified (10) Structure (18 - 1 cryst) Characterized (124)
| 1 | 2 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-N-acetylglucosaminidase (β-chain) / β-hexosaminidase B (HexB) 3.2.1.52 Mus musculus AAA18776.1
AAA74738.1
AAB60667.1
BAE30155.1
BAE34846.1
BAE34877.1
BAE35874.1
BAE40652.1
CAA68781.1
NP_034552.1
P20060
Q3TXR9
 
 N-acetylglucosaminidase 3.2.1.52 Neotyphodium sp. FCB-2004 AAU29327.1 Q643Y1  
 β-N-acetylhexosaminidase (Fdl;OfFDL) 3.2.1.52 Ostrinia furnacalis ADF97235.1 D6PW84  
 β-N-acetylhexosaminidase (Hex1;OfHex1) 3.2.1.52 Ostrinia furnacalis ABI81756.1 Q06GJ0 3NSM[A]
3NSN[A]
3OZO[A]
3OZP[A]
3S6T[A]
3VTR[A]
3WMB[A]
3WMC[A]
 β-N-acetylhexosaminidase (Hex2;OfHEX2) 3.2.1.52 Ostrinia furnacalis ABO65045.1 A4LAF9  
 hexosaminidase 3 (Hex3;OfHex3) 3.2.1.52 Ostrinia furnacalis ABV79901.1 A8IDA5  
 β-N-acetylhexosaminidase (NagA;Hex;Pen ch 20) 3.2.1.52 Penicillium chrysogenum AAF00010.1
AAP66194.1
AAQ80154.1
Q02352
Q9URR8
 
 β-N-acetylhexosaminidase (Hex;PoHex) 3.2.1.52 Penicillium oxalicum CCF 1959 / CCF 3438 ABY57948.1 E3NYM0  
 β-N-acetylglucosaminidase 3 (HexA;Hex;GlcNAcase3;SfGlcNAcase3) 3.2.1.52 Spodoptera frugiperda ABA27426.1
ABB76926.1
ABY57947.1
Q3LS76  
 β-N-acetylglucosaminidase 2 (HexB;Hex;SfHex) 3.2.1.52 Spodoptera frugiperda ABA27427.1
ABB76925.1
Q3LS75  
 β-N-acetylglucosaminidase 1 (GlcNAcase1;SfGlcNAcase1) 3.2.1.52 Spodoptera frugiperda ABB76924.1 Q2Q1D3  
 processing β-N-acetylglucosaminidase (Fdl;SfFDL;Sf-Fdl) 3.2.1.52 Spodoptera frugiperda ACA30398.1 B1P868  
 β-N-acetylhexosaminidase (HexB) 3.2.1.52 Sus scrofa CAA63123.1
BAI47712.1
Q29548  
 β-N-acetylhexosaminidase (HexTF) 3.2.1.52 Talaromyces flavus CCF2686 AEQ33603.1    
 β-hexosaminidase (Bhex) 3.2.1.52 Tetrahymena thermophila CAD55811.1 Q8IEV5  
 β-N-acetylglucosaminidase (Nag2;TRIATDRAFT_41039) 3.2.1.52 Trichoderma atroviride IMI 206040 EHK46127.1    
 β-N-acetylglucosaminidase (Nag1;Nag70;Chit73) 3.2.1.52 Trichoderma atroviride P1 AAB50829.1 P87258  
 β-N-acetylglucosaminidase (Nag2) (fragment) 3.2.1.52 Trichoderma atroviride P1 ABC95196.1 Q0ZLH7  
 exo-chitinase 1 (Exc1) 3.2.1.52 Trichoderma harzianum AAB47060.1 P78738  
 exo-chitinase 2 (Exc2) 3.2.1.52 Trichoderma harzianum AAB47061.1 P78739  
 hexosaminidase (Exc1y) 3.2.1.52 Trichoderma harzianum T-Y CAC85402.1 Q8NIN7  
 hexosaminidase (Exc2y) 3.2.1.52 Trichoderma harzianum T-Y CAC85401.1 Q8NIN6  
 β-N-acetylglucosaminidase (Nag1;TRIREDRAFT_21725) 3.2.1.52 Trichoderma reesei QM6a / RutC30?U3 EGR50812.1    
 exochitinase 2 (Zm.15748;ZmExo2;LOC100280178;ZM_BFb0204B20) 3.2.1.52 Zea mays B73 ACF87335.1
ACG29631.1
ACL54323.1
B4FYZ2  
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