Glycoside Hydrolase Family 1

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-β-1,4-glucanase (EC 3.2.1.74); 6-phospho-β-galactosidase (EC 3.2.1.85); 6-phospho-β-glucosidase (EC 3.2.1.86); strictosidine β-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin β-glucosidase (EC 3.2.1.117); prunasin β-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine β-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); β-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-β-apiosyl-β-glucosidase (EC 3.2.1.161); ABA-specific β-glucosidase (EC 3.2.1.175); DIMBOA β-glucosidase (EC 3.2.1.182); β-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (18476); Uniprot accession (2276); PDB accession (232); 3D entries (53); cryst (0)
All (16460) Archaea (143) Bacteria (15249) Eukaryota (1026) Viruses (1) unclassified (41) Structure (53) Characterized (336)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 11 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01668.1 E5AEM9  
 hydroxynitrile glucoside-cleaving β-glucosidase (Bglu1;LlBglu1 3.2.1.21 Leucaena leucocephala ABY48758.1
ABI34907.1
ABI34907.2
ABI34907.3
ABY84677.1
B0LJR5  
 ORF (fragment)   Leucaena leucocephala ABK60303.2 A0SXU2  
 unnamed protein product   Linum usitatissimum CBD31903.1    
 cell wall glycosidase (fragment)   Linum usitatissimum ABM64783.1 A2IBG8  
 Klotho (fragment)   Lipotes vexillifer ADZ57971.1    
 β-glucosidase 31, partial (fragment)   Lolium perenne AFA36600.1    
 β-glucosidase, partial (fragment)   Lotus arenarius AGZ83062.1    
 β-glucosidase, partial (fragment)   Lotus burttii AGZ83066.1    
 β-glucosidase, partial (fragment)   Lotus conimbricensis AII26337.1    
 β-glucosidase, partial (fragment)   Lotus corniculatus AII26340.1    
 β-glucosidase, partial (fragment)   Lotus corniculatus AII26339.1    
 β-glucosidase, partial (fragment)   Lotus corniculatus AII26341.1    
 β-glucosidase, partial (fragment)   Lotus corniculatus AII26342.1    
 ORF (fragment)   Lotus drepanocarpus AGZ83063.1    
 β-glucosidase, partial (fragment)   Lotus edulis AII26338.1    
 β-glucosidase, partial (fragment)   Lotus filicaulis AGZ83061.1    
 unknown (fragment)   Lotus japonicus AFK38801.1    
 unknown (fragment)   Lotus japonicus AFK40243.1    
 unknown (fragment)   Lotus japonicus AFK43877.1    
 unknown (fragment)   Lotus japonicus AFK47660.1    
 β-glucosidase (LjBGD10)   Lotus japonicus AGS43007.1    
 β-glucosidase D7 (LjBGD7)   Lotus japonicus ACD65511.1
AFK35989.1
B2ZUU2  
 hydroxynitrile β-glucosidase D2 (LjBGD2) 3.2.1.21 Lotus japonicus ACD65510.1 B2ZUU1  
 hydroxynitrile β-glucosidase D4 (LjBGD4) 3.2.1.21 Lotus japonicus ACD65509.1
AFK44931.1
B2ZUU0  
 β-glucosidase, partial (fragment)   Lotus krylovii AGZ83064.1    
 β-glucosidase, partial (fragment)   Lotus ornithopodioides AGZ83060.1    
 β-glucosidase, partial (fragment)   Lotus tenuis AGZ83065.1    
 β-glucosidase, partial (fragment)   Lotus tenuis AII26336.1    
 β-glucosidase (fragment)   Lotus tenuis AII26335.1    
 β-glucosidase, partial (fragment)   Lotus weilleri AII26334.1    
 ORF (fragment)   Lumnitzera racemosa AGU71380.1    
 β-glucosidase 3   Lygus lineolaris AHG54239.1    
 β-glucosidase 1   Lygus lineolaris AHG54237.1    
 β-glucosidase 4   Lygus lineolaris AHG54240.1    
 β-glucosidase 5, partial   Lygus lineolaris AHG54241.1    
 β-glucosidase 5b, partial (fragment)   Lygus lineolaris AHG54242.1    
 beta glucosidase 6 (Bglu6)   Lygus lineolaris AOH73347.1    
 ORF (fragment)   Macaca mulatta AFE73622.1    
 ORF (fragment)   Macaca mulatta AFE74118.1    
 β-glucosidase 23   Macrobrachium nipponense AHJ10948.1    
 β-glucosidase (MbmgBG1) 3.2.1.21 Macrotermes barneyi AFD33364.1    
 β-glucosidase (McBG)   Macrotermes carbonarius AGP76179.1    
 ORF   Magnaporthe grisea Y34 AAX07701.1 Q5EMV2  
 MG10189.4   Magnaporthe oryzae 70-15 XP_365969.1    
 MG09738.4   Magnaporthe oryzae 70-15 XP_364893.1 G4NA47  
 β-glucosidase (ASG) 3.2.1.21 Malus domestica AEN94900.1    
 β-D-glucosidase, partial (fragment)   Mangifera indica AJZ77345.1    
 β-glucosidase (linamarase) 3.2.1.21 Manihot esculenta AAB71381.1
CAW42866.1
CAW48569.1
CBC08394.1
CBD21362.1
O24524  
 β-glucosidase A 3.2.1.21 Manihot esculenta CAA64442.1
CAW42870.1
CAW48573.1
CBC08398.1
CBD21366.1
CBG21203.1
Q40283  
 β-glucosidase (linamarase) 3.2.1.21 Manihot esculenta AAB22162.1
CAW42872.1
CAW48575.1
CBC08400.1
CBD21368.1
CBG21204.1
Q41172  
 Klotho (fragment)   Manis pentadactyla AEB78527.1    
 β-glucosidase (fragment)   Medicago sativa AAZ31067.1 Q45R29  
 ORF (fragment)   Medicago sativa AAZ32913.1 Q45NG9  
 Mtc424 (fragment)   Medicago truncatula AAK92453.1 Q94ET2  
 MTYFL_FM_FN_FO1G-N-14   Medicago truncatula ACJ85833.1 B7FM50  
 MTYFL_FM_FN_FO1G-A-7 (fragment)   Medicago truncatula ACJ85633.1
AFK40248.1
B7FLJ9  
 unknown   Medicago truncatula AFK45464.1    
 unknown   Medicago truncatula AFK37869.1    
 unknown (fragment)   Medicago truncatula AFK37966.1    
 unknown (fragment)   Medicago truncatula AFK42730.1    
 unknown (fragment)   Medicago truncatula AFK49164.1    
 MtrDRAFT_AC152499g15v1   Medicago truncatula ABE77795.1
ABO83603.1
ABO83604.1
AFK44109.1
AFK46781.1
   
 MtrDRAFT_AC152499g17v1 + MtrDRAFT_AC152499g16v1   Medicago truncatula ABE77796.1
ABE77797.1
ABE77797.2
ACJ85625.1
   
 MtrDRAFT_AC133864g31v1   Medicago truncatula ABE79403.1 G7IZC8  
 MtrDRAFT_AC140721g1v1 (fragment)   Medicago truncatula ABE79608.1    
 MtrDRAFT_AC140022g25v1 or MtrDRAFT_AC156629g15v1   Medicago truncatula ABE80355.1
ABE80355.2
ABE86381.1
ABE86381.2
AFK35893.1
G7KKR4  
 MtrDRAFT_AC146567g28v1   Medicago truncatula ABE90952.1 G7JHH4  
 MtrDRAFT_AC146574g18v1   Medicago truncatula ABO81445.1
ABE90582.1
   
 β-glucosidase G1 (MtrDRAFT_AC138016g10v1)   Medicago truncatula ABE80780.1
ABW76286.1
A8TVQ0  
 MtrDRAFT_AC138016g14v1   Medicago truncatula ABE80784.1    
 MtrDRAFT_AC156629g4v1   Medicago truncatula ABE86378.1    
 MtrDRAFT_AC156629g9v1   Medicago truncatula ABE86373.1 G7KKS5  
 MtrDRAFT_AC150786g22v1   Medicago truncatula ABE85996.1    
 MtrDRAFT_AC150786g6v1 + MtrDRAFT_AC150786g11v1   Medicago truncatula ABE85992.1
ABE85993.1
   
 MtrDRAFT_AC161032g2v1   Medicago truncatula ABE85054.1
ABE84996.1
G7IF65  
 MtrDRAFT_AC161032g11v1   Medicago truncatula ABE85051.1
ABO83962.1
ABO83963.1
   
 MtrDRAFT_AC124959g23v1   Medicago truncatula ABE83886.1 G7I6K4  
 MtrDRAFT_AC146785g42v2 (fragment)   Medicago truncatula ABO81808.1    
 β-glucosidase G2   Medicago truncatula ABW76287.1
ACJ85659.1
A8TVQ5  
 β-glucosidase G3   Medicago truncatula ABW76288.1 A8TVQ9  
 β-glucosidase G4   Medicago truncatula ABW76289.1 A8TVR1  
 klotho (KL) (fragment)   Mesoplodon densirostris ADZ53998.1    
 GH1 β-glucosidase (BG)   Microcerotermes annandalei APM84101.1    
 β-glucosidase   Microtermes sp. KAY-2015 AKV16372.1    
 GNLVRS01_PISO0H17541g (Piso0_003675)   Millerozyma farinosa CBS 7064 CCE81321.1    
 GNLVRS01_PISO0G17540g (Piso0_003675)   Millerozyma farinosa CBS 7064 CCE80556.1    
 GNLVRS01_PISO0D13159g (Piso0_001200)   Millerozyma farinosa CBS 7064 CCE79159.1    
 GNLVRS01_PISO0C13092g (Piso0_001200)   Millerozyma farinosa CBS 7064 CCE78573.1    
 β-klotho, partial   Mirounga angustirostris BAR43364.1    
 strictosidine β-D-glucosidase, partial (SgD) (fragment)   Mitragyna speciosa AFB70991.1    
 Klotho (fragment)   Moschus moschiferus ADZ57982.1    
 KLPH   Mus musculus AAM77699.1
AAH30631.1
BAC35414.1
NP_665834.1
Q8BPR1
Q8K1F9
Q8K2M9
 
 klotho (β-glucuronidase and sialidase activity) (KL) 3.2.1.18
3.2.1.31
Mus musculus AAQ41830.1
AAI38260.1
BAA23381.1
BAA25308.1
BAE22211.1
CAC42188.1
NP_038851.1
O35082  
 klotho (β-glucuronidase and sialidase activity) (KL) 3.2.1.18
3.2.1.31
Mus musculus AAQ41830.1
AAI38260.1
BAA23381.1
BAA25308.1
CAC42188.1
NP_038851.1
O35082  
 klotho (secreted)   Mus musculus BAA25307.1
AAQ41831.1
BAA25309.1
CAC42187.1
O35082  
 lactase-phlorizin hydrolase (Lct;LPH)   Mus musculus NP_001074547.1
BAE34332.1
Q3TZ78  
 lactase-phlorizin hydrolase (Lct;LPH)   Mus musculus NP_001074547.1
AAU95234.1
BAE34332.1
Q3TZ78
Q5XLR9
 
 β-Klotho (KLb;β-KL)   Mus musculus AAK28704.1
AAL01648.1
NP_112457.1
B2RQN8
Q920J2
Q99N32
 
 β-Klotho (KLb;β-KL)   Mus musculus AAK28704.1
AAK28705.1
AAL01648.1
AGO86320.1
NP_112457.1
B2RQN8
Q920J2
Q99N31
Q99N32
 
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